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The map label for this gene is ubiB [H]

Identifier: 91786765

GI number: 91786765

Start: 886307

End: 887860

Strand: Direct

Name: ubiB [H]

Synonym: Bpro_0863

Alternate gene names: 91786765

Gene position: 886307-887860 (Clockwise)

Preceding gene: 91786764

Following gene: 91786766

Centisome position: 17.04

GC content: 62.29

Gene sequence:

>1554_bases
ATGACCCGGGTGTTCAGGGGCGGGTTCATCGTTTGGACCGTGCTTCGCTTCGGCCTCGACGAACTGGTGTTGTCCAGCTT
CGAAAAGCCGTGGATCCGCCGGTTGACCCGCATCGTCTCGCTGGGGCGCAACCTGAGCGCTCCCCGTGGCGCCCGTCTTC
GCGAGGCACTGGAAGCGCTGGGGCCCATCTTCGTCAAGTTCGGGCAGGTGATGTCCACACGGCGCGACCTGCTGCCGCCC
GACATCGCCGATGAGCTGGCGCGCCTGCAGGACCGGGTGCCACCCTTTGAATCGTCGGTGGCCGTTGCCATCATCGAAAA
GGCGTTTGGCCGGCCCCTGGACCGTATATTCGCGACGTTTGAGCACACCCCCGTGGCCAGCGCGTCGATTGCCCAGGTTC
ACTTTGCGACGCTGCACGACGGCCGTGAAGTGGCAGTCAAGGTATTGCGCCCCAACATGCTGCCCGCGATCGAGAAAGAC
CTCGCGCTCATGCACATGATGGCCGGCTGGGTGGAAGGCGCATCCGCCGATGGCAAGCGCCTCAAGCCGCGCGAAGTGGT
AGCCGAGTTTGACAAATACCTGCACGACGAGCTCGACTTGCTGCGTGAGGCCGCCAATGCGGCGCAACTGCGCCGGAACA
TGCAGGACCTCAATCTCGTCATGATCCCGGAAATGTTCTGGGACTACTGCATGCCCGATGTCATGGTGATGGAGCGCATG
AAGGGGGTGCCCATCGGCCAGAGCCAGCGCCTGCGCGACGCCAGCGTGGACATGAAGAAGCTGGCTCGCGACGGCGTCAC
CATTTTCTTCACGCAGGTGTTCCGCGATGGCTTTTTTCATGCCGACATGCACCCGGGCAATATTCAGGTCAGCCTGGCCC
CGGACACCTTCGGGCGCTATATTTCGCTGGATTTCGGCATCGTGGGCACGCTCACAGAGGTGGACAAGGAGTATCTGGCG
CACAACTTCAGCGCTTTCTTCCAGCGCGACTACAAGCGCGTTGCCGAACTGCATCTGGAGTCCGGCTGGGTGCCCGCCAC
CACCCGTGTGGACGAGCTGGAAGCCGCCATTCGCGCCTGCTGCGAGCCGTATTTCGACCGGCCGCTCAAGGAAATCTCGC
TGGGCCTGGTGCTGATGCGCCTGTTCCAGACCTCGCGCCGTTTCCACGTGGAAATTCAGCCGCAACTGGTCCTGCTGCAA
AAAACCCTGCTCAATATCGAAGGGCTGGGGCGCGAACTGGATCCCGAACTTGACCTCTGGAGCACGGCCAAGCCTTTTCT
TGAAAAATGGATGCTGGAGCAGGTGGGCCCCGAAAAATTGCTGGCCCAGCTCAAGGCCGAGGCCCCGGCCTATGCCAAGC
TGCTGCCCGTGCTGCCGCGCCTGCTGGCCCAGTACCTCAAAGGGCCGTCAGGGCCGAGCCGCCGCGACCTGGAAGCCCTG
CTGGCCGAACAAAAGCGCACCAACAAACTGCTGCAAAGCCTGATCTACGGTGGTTTGGGCTTTGTGCTGGGCCTGATTGC
CATGCAACTGCTGCTGCGGGTCCGTATTTTTTGA

Upstream 100 bases:

>100_bases
CACCGCTGTCCCCGTCCTCATCTTCCCCTTCATCCCCTACCTCATCTCCCACTTCATCCGCAGCGTCCGGTTCCTCCCCG
GATGCCGCGAAGGCTTCTGC

Downstream 100 bases:

>100_bases
CGCCGGCCCGAGCCGGCTGCCGCACAGGTCCGAACGCTGTGGGTCTCCCCGCCCGTTTGCCTTGAAGTTGGCGGCAACGC
CTATAATTGAAGGTTTTGCA

Product: putative ubiquinone biosynthesis protein UbiB

Products: 2-octaprenyl-6-hydroxyphenol [C]

Alternate protein names: NA

Number of amino acids: Translated: 517; Mature: 516

Protein sequence:

>517_residues
MTRVFRGGFIVWTVLRFGLDELVLSSFEKPWIRRLTRIVSLGRNLSAPRGARLREALEALGPIFVKFGQVMSTRRDLLPP
DIADELARLQDRVPPFESSVAVAIIEKAFGRPLDRIFATFEHTPVASASIAQVHFATLHDGREVAVKVLRPNMLPAIEKD
LALMHMMAGWVEGASADGKRLKPREVVAEFDKYLHDELDLLREAANAAQLRRNMQDLNLVMIPEMFWDYCMPDVMVMERM
KGVPIGQSQRLRDASVDMKKLARDGVTIFFTQVFRDGFFHADMHPGNIQVSLAPDTFGRYISLDFGIVGTLTEVDKEYLA
HNFSAFFQRDYKRVAELHLESGWVPATTRVDELEAAIRACCEPYFDRPLKEISLGLVLMRLFQTSRRFHVEIQPQLVLLQ
KTLLNIEGLGRELDPELDLWSTAKPFLEKWMLEQVGPEKLLAQLKAEAPAYAKLLPVLPRLLAQYLKGPSGPSRRDLEAL
LAEQKRTNKLLQSLIYGGLGFVLGLIAMQLLLRVRIF

Sequences:

>Translated_517_residues
MTRVFRGGFIVWTVLRFGLDELVLSSFEKPWIRRLTRIVSLGRNLSAPRGARLREALEALGPIFVKFGQVMSTRRDLLPP
DIADELARLQDRVPPFESSVAVAIIEKAFGRPLDRIFATFEHTPVASASIAQVHFATLHDGREVAVKVLRPNMLPAIEKD
LALMHMMAGWVEGASADGKRLKPREVVAEFDKYLHDELDLLREAANAAQLRRNMQDLNLVMIPEMFWDYCMPDVMVMERM
KGVPIGQSQRLRDASVDMKKLARDGVTIFFTQVFRDGFFHADMHPGNIQVSLAPDTFGRYISLDFGIVGTLTEVDKEYLA
HNFSAFFQRDYKRVAELHLESGWVPATTRVDELEAAIRACCEPYFDRPLKEISLGLVLMRLFQTSRRFHVEIQPQLVLLQ
KTLLNIEGLGRELDPELDLWSTAKPFLEKWMLEQVGPEKLLAQLKAEAPAYAKLLPVLPRLLAQYLKGPSGPSRRDLEAL
LAEQKRTNKLLQSLIYGGLGFVLGLIAMQLLLRVRIF
>Mature_516_residues
TRVFRGGFIVWTVLRFGLDELVLSSFEKPWIRRLTRIVSLGRNLSAPRGARLREALEALGPIFVKFGQVMSTRRDLLPPD
IADELARLQDRVPPFESSVAVAIIEKAFGRPLDRIFATFEHTPVASASIAQVHFATLHDGREVAVKVLRPNMLPAIEKDL
ALMHMMAGWVEGASADGKRLKPREVVAEFDKYLHDELDLLREAANAAQLRRNMQDLNLVMIPEMFWDYCMPDVMVMERMK
GVPIGQSQRLRDASVDMKKLARDGVTIFFTQVFRDGFFHADMHPGNIQVSLAPDTFGRYISLDFGIVGTLTEVDKEYLAH
NFSAFFQRDYKRVAELHLESGWVPATTRVDELEAAIRACCEPYFDRPLKEISLGLVLMRLFQTSRRFHVEIQPQLVLLQK
TLLNIEGLGRELDPELDLWSTAKPFLEKWMLEQVGPEKLLAQLKAEAPAYAKLLPVLPRLLAQYLKGPSGPSRRDLEALL
AEQKRTNKLLQSLIYGGLGFVLGLIAMQLLLRVRIF

Specific function: Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis [H]

COG id: COG0661

COG function: function code R; Predicted unusual protein kinase

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC1 family. UbiB subfamily [H]

Homologues:

Organism=Homo sapiens, GI40254938, Length=290, Percent_Identity=31.0344827586207, Blast_Score=136, Evalue=5e-32,
Organism=Homo sapiens, GI41393593, Length=270, Percent_Identity=28.5185185185185, Blast_Score=119, Evalue=7e-27,
Organism=Homo sapiens, GI217035081, Length=226, Percent_Identity=32.7433628318584, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI32261307, Length=314, Percent_Identity=29.2993630573248, Blast_Score=108, Evalue=9e-24,
Organism=Homo sapiens, GI27363457, Length=282, Percent_Identity=26.5957446808511, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI217416386, Length=222, Percent_Identity=29.2792792792793, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI34147522, Length=216, Percent_Identity=28.7037037037037, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI2367309, Length=516, Percent_Identity=50.3875968992248, Blast_Score=478, Evalue=1e-136,
Organism=Caenorhabditis elegans, GI17559152, Length=254, Percent_Identity=27.1653543307087, Blast_Score=108, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI32565180, Length=288, Percent_Identity=26.3888888888889, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6325148, Length=453, Percent_Identity=26.4900662251656, Blast_Score=123, Evalue=6e-29,
Organism=Saccharomyces cerevisiae, GI6323282, Length=256, Percent_Identity=26.171875, Blast_Score=76, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6321319, Length=223, Percent_Identity=26.0089686098655, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24662575, Length=246, Percent_Identity=30.8943089430894, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI22024280, Length=251, Percent_Identity=29.0836653386454, Blast_Score=116, Evalue=5e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004147
- InterPro:   IPR011009
- InterPro:   IPR010232 [H]

Pfam domain/function: PF03109 ABC1 [H]

EC number: NA

Molecular weight: Translated: 58702; Mature: 58570

Theoretical pI: Translated: 8.74; Mature: 8.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRVFRGGFIVWTVLRFGLDELVLSSFEKPWIRRLTRIVSLGRNLSAPRGARLREALEAL
CCCEECCHHHHHHHHHHCHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
GPIFVKFGQVMSTRRDLLPPDIADELARLQDRVPPFESSVAVAIIEKAFGRPLDRIFATF
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCHHHHHHHH
EHTPVASASIAQVHFATLHDGREVAVKVLRPNMLPAIEKDLALMHMMAGWVEGASADGKR
CCCCCCCHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCC
LKPREVVAEFDKYLHDELDLLREAANAAQLRRNMQDLNLVMIPEMFWDYCMPDVMVMERM
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHCCHHHHHHHHH
KGVPIGQSQRLRDASVDMKKLARDGVTIFFTQVFRDGFFHADMHPGNIQVSLAPDTFGRY
CCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCE
ISLDFGIVGTLTEVDKEYLAHNFSAFFQRDYKRVAELHLESGWVPATTRVDELEAAIRAC
EEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
CEPYFDRPLKEISLGLVLMRLFQTSRRFHVEIQPQLVLLQKTLLNIEGLGRELDPELDLW
HHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHCCCCCCCCCCCC
STAKPFLEKWMLEQVGPEKLLAQLKAEAPAYAKLLPVLPRLLAQYLKGPSGPSRRDLEAL
CCHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
LAEQKRTNKLLQSLIYGGLGFVLGLIAMQLLLRVRIF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TRVFRGGFIVWTVLRFGLDELVLSSFEKPWIRRLTRIVSLGRNLSAPRGARLREALEAL
CCEECCHHHHHHHHHHCHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
GPIFVKFGQVMSTRRDLLPPDIADELARLQDRVPPFESSVAVAIIEKAFGRPLDRIFATF
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCHHHHHHHH
EHTPVASASIAQVHFATLHDGREVAVKVLRPNMLPAIEKDLALMHMMAGWVEGASADGKR
CCCCCCCHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCC
LKPREVVAEFDKYLHDELDLLREAANAAQLRRNMQDLNLVMIPEMFWDYCMPDVMVMERM
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHCCHHHHHHHHH
KGVPIGQSQRLRDASVDMKKLARDGVTIFFTQVFRDGFFHADMHPGNIQVSLAPDTFGRY
CCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCE
ISLDFGIVGTLTEVDKEYLAHNFSAFFQRDYKRVAELHLESGWVPATTRVDELEAAIRAC
EEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
CEPYFDRPLKEISLGLVLMRLFQTSRRFHVEIQPQLVLLQKTLLNIEGLGRELDPELDLW
HHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHCCCCCCCCCCCC
STAKPFLEKWMLEQVGPEKLLAQLKAEAPAYAKLLPVLPRLLAQYLKGPSGPSRRDLEAL
CCHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
LAEQKRTNKLLQSLIYGGLGFVLGLIAMQLLLRVRIF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2 2-octaprenylphenol; O2 [C]

Specific reaction: 2 2-octaprenylphenol + O2 = 2 2-octaprenyl-6-hydroxyphenol [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA