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The map label for this gene is coaE [H]

Identifier: 91786746

GI number: 91786746

Start: 867221

End: 867844

Strand: Direct

Name: coaE [H]

Synonym: Bpro_0844

Alternate gene names: 91786746

Gene position: 867221-867844 (Clockwise)

Preceding gene: 91786745

Following gene: 91786747

Centisome position: 16.68

GC content: 65.06

Gene sequence:

>624_bases
ATGCCCTTCGCAGCCCAGCGTATCGGACTGACTGGCGGCATAGGCAGCGGCAAGAGTACGGTGGCCCGCCTGCTGGTGGG
ACGGGGCGCAACGCTGGTCGATGCAGACGCCATCGCCCGTCAGGTGACGGCGCCTGGAGGCGCTGCCATCAACGAAATCG
CCCGCCAGTTTGGAAGCGCCGCCCTCACGGCCAGCGGGGCCATGGACCGTGACCGGATGCGTCTGCTTGCCTTCAACGAC
CCGGCAGTCAGGCGGCAGCTGGAGGCCATCATCCACCCCTTGGTGAGCCAGGAAAGCTCGCGGCAGTACAGCCAAGCCGC
GCAGGCGGGCAGTTCATGCATCGTTTTTGATATTCCCTTGCTGGTCGAGTCGGGGCGCTGGCGGCAGCAGCTGGACCGGG
TTCTGGTGGTGGACTGCAGCGAAGCCACCCAGATCGCCCGGGTCATGGCCCGCGAACTCGGGCGCAGCGGCTGGACGCGT
GAAGTTGTTGAAAAAATAATCGATGGGCAGGCCAGCCGCGCGCAGCGGCTGGGGGCAGCCGATATCTGCATCTATAACGA
TGGCCTGTCTCTTGAAGCCCTTGGCTTGCAGGTGGCACAGCTTGCAAGCCGCTTCGGGCTATGA

Upstream 100 bases:

>100_bases
GGCGGTTACGTGCCGTTTGGCCCTTTCCTGGCGGGTGCGGGATTTACCGCCATGGTGTTCGGGCCTCAATCGATTCTGCA
GTTTGTGGGTTTGTGATGCC

Downstream 100 bases:

>100_bases
TGCGCAGACAAGCATTCCCCATGAAGTTGACGAAAATAGCGCTGTGATTCTTTACGAGTATCCTTTTAACGAACGCATAC
GCACCTATTTGCGCCTGGAG

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 207; Mature: 206

Protein sequence:

>207_residues
MPFAAQRIGLTGGIGSGKSTVARLLVGRGATLVDADAIARQVTAPGGAAINEIARQFGSAALTASGAMDRDRMRLLAFND
PAVRRQLEAIIHPLVSQESSRQYSQAAQAGSSCIVFDIPLLVESGRWRQQLDRVLVVDCSEATQIARVMARELGRSGWTR
EVVEKIIDGQASRAQRLGAADICIYNDGLSLEALGLQVAQLASRFGL

Sequences:

>Translated_207_residues
MPFAAQRIGLTGGIGSGKSTVARLLVGRGATLVDADAIARQVTAPGGAAINEIARQFGSAALTASGAMDRDRMRLLAFND
PAVRRQLEAIIHPLVSQESSRQYSQAAQAGSSCIVFDIPLLVESGRWRQQLDRVLVVDCSEATQIARVMARELGRSGWTR
EVVEKIIDGQASRAQRLGAADICIYNDGLSLEALGLQVAQLASRFGL
>Mature_206_residues
PFAAQRIGLTGGIGSGKSTVARLLVGRGATLVDADAIARQVTAPGGAAINEIARQFGSAALTASGAMDRDRMRLLAFNDP
AVRRQLEAIIHPLVSQESSRQYSQAAQAGSSCIVFDIPLLVESGRWRQQLDRVLVVDCSEATQIARVMARELGRSGWTRE
VVEKIIDGQASRAQRLGAADICIYNDGLSLEALGLQVAQLASRFGL

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=145, Percent_Identity=36.551724137931, Blast_Score=105, Evalue=2e-23,
Organism=Homo sapiens, GI191252795, Length=145, Percent_Identity=36.551724137931, Blast_Score=105, Evalue=2e-23,
Organism=Homo sapiens, GI110227607, Length=152, Percent_Identity=28.9473684210526, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI110227605, Length=152, Percent_Identity=28.9473684210526, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI110227603, Length=152, Percent_Identity=28.9473684210526, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI110227601, Length=152, Percent_Identity=28.9473684210526, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI205277394, Length=152, Percent_Identity=28.9473684210526, Blast_Score=73, Evalue=2e-13,
Organism=Escherichia coli, GI1786292, Length=198, Percent_Identity=41.9191919191919, Blast_Score=133, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17554944, Length=190, Percent_Identity=32.1052631578947, Blast_Score=109, Evalue=8e-25,
Organism=Saccharomyces cerevisiae, GI6320402, Length=189, Percent_Identity=29.6296296296296, Blast_Score=78, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24644728, Length=187, Percent_Identity=30.4812834224599, Blast_Score=98, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24658602, Length=156, Percent_Identity=30.7692307692308, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 22032; Mature: 21900

Theoretical pI: Translated: 8.92; Mature: 8.92

Prosite motif: PS01294 COAE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFAAQRIGLTGGIGSGKSTVARLLVGRGATLVDADAIARQVTAPGGAAINEIARQFGSA
CCCCCHHCCCCCCCCCCHHHHHHHHHCCCCCEECHHHHHHHHCCCCCHHHHHHHHHHCCH
ALTASGAMDRDRMRLLAFNDPAVRRQLEAIIHPLVSQESSRQYSQAAQAGSSCIVFDIPL
HHHHCCCCCHHHEEEEEECCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEEEHHH
LVESGRWRQQLDRVLVVDCSEATQIARVMARELGRSGWTREVVEKIIDGQASRAQRLGAA
HHCCCCHHHHHCCEEEEECHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHCCCC
DICIYNDGLSLEALGLQVAQLASRFGL
EEEEECCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PFAAQRIGLTGGIGSGKSTVARLLVGRGATLVDADAIARQVTAPGGAAINEIARQFGSA
CCCCHHCCCCCCCCCCHHHHHHHHHCCCCCEECHHHHHHHHCCCCCHHHHHHHHHHCCH
ALTASGAMDRDRMRLLAFNDPAVRRQLEAIIHPLVSQESSRQYSQAAQAGSSCIVFDIPL
HHHHCCCCCHHHEEEEEECCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEEEHHH
LVESGRWRQQLDRVLVVDCSEATQIARVMARELGRSGWTREVVEKIIDGQASRAQRLGAA
HHCCCCHHHHHCCEEEEECHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHCCCC
DICIYNDGLSLEALGLQVAQLASRFGL
EEEEECCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA