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The map label for this gene is hisC [H]

Identifier: 91786707

GI number: 91786707

Start: 831400

End: 832476

Strand: Direct

Name: hisC [H]

Synonym: Bpro_0805

Alternate gene names: 91786707

Gene position: 831400-832476 (Clockwise)

Preceding gene: 91786706

Following gene: 91786708

Centisome position: 15.99

GC content: 62.12

Gene sequence:

>1077_bases
ATGACCGCGCTGGACCCGAAGTTCAAACAGCTGATTCGCCAGGACGTGCAGTCCATGCATGCCTATGCCATTCAGGACTC
CGTTGGCATGGTCAAGCTCGATGCAATGGAGAACCCGTATCGGCTGCCGGCCGCGTTGCAGGCCCATCTCGGGCAGCGGC
TGGGCGCGCTGGCGCTGAATCGCTACCCTGACGGCCGCGTCAACGACCTGCGCCAGGCCCTGGCAGACTACGCCCGGATG
CCAGAAGGCTTTGACATCATGCTGGGCAACGGCTCGGACGAGCTGATTTCGCTGCTGGCCATGGCCTGCGACGTGCCGGG
CGGCTCCATCCTGGCGCCGCTGCCGGGCTTTGTGATGTACGGCATGAGCGCACAGCTGCAGGGCCTCAAGTTCACGGGTG
TGCCGCTCACGGCTGACTTTGAGCTCGACGAAGCCGCCATGCTGGCCGCCATCGCCGAGCACCGGCCGTCCATCATTTAC
CTGGCCTACCCGAACAACCCCACCGCCAACCTGTGGGACGATACCGTCATTGAGAAAATCATCACCGCAGCGCCCGGTCT
GGTGGTGATGGACGAGGCCTACCAGCCGTTTTCCAGCAAAAGCTATATCGACCGCATTGCCAGGCACAGCCATGTGCTGC
TGATGCGCACCCTCAGCAAGTTTGGGCTGGCCGGCGTGCGCATTGGCTACATGATGGGCCCGAAGGCCCTGATTGCCGAG
ATCGACAAGGTGCGCCCGCCCTACAACATCAGTGTGCTCAATTACGAGTGCGCGCTGTTTGCGCTGGAGCACCGGGAAGT
GTTCGCCGAGCAGGCCGCGGCCGTGGTCGCGCAGCGCACCATGCTGCTGGACGCGCTGGCGGCCATGAAGGGCGTCAAGG
CCTGGAAAAGCGACGCCAACATGATCCTGGTGCGGGTCCCGGATGCGGCCAAAACCTTTGAAGGCATGAAGTCGCGCCAT
GTGCTGGTCAAAAACGTTTCTAAAATGCATCCATTGCTGGCCAATTGTTTGCGCCTGACCGTCGGCACCGCGGACGAGAA
TACGCAAATGCTGGCGGCGCTTGAAAAATCCCTATGA

Upstream 100 bases:

>100_bases
GCAGGATTGCCGCTGAACTGGCCTACGGCGAAGGTCTGCAGGCGCATGCCCGCGCCGCCGAGATGCGCCTGCACACCGTA
CCCGATATGAAAGTGACCAA

Downstream 100 bases:

>100_bases
CCACCCCTTCCACTGCTCCGACCCCGGCCCCGCGCAAGGCGGAAGTCTCGCGCAACACCGCCGAGACCCAGATCACCGTC
AAGCTCAACCTGGACGGCAC

Product: histidinol-phosphate aminotransferase

Products: NA

Alternate protein names: Imidazole acetol-phosphate transaminase [H]

Number of amino acids: Translated: 358; Mature: 357

Protein sequence:

>358_residues
MTALDPKFKQLIRQDVQSMHAYAIQDSVGMVKLDAMENPYRLPAALQAHLGQRLGALALNRYPDGRVNDLRQALADYARM
PEGFDIMLGNGSDELISLLAMACDVPGGSILAPLPGFVMYGMSAQLQGLKFTGVPLTADFELDEAAMLAAIAEHRPSIIY
LAYPNNPTANLWDDTVIEKIITAAPGLVVMDEAYQPFSSKSYIDRIARHSHVLLMRTLSKFGLAGVRIGYMMGPKALIAE
IDKVRPPYNISVLNYECALFALEHREVFAEQAAAVVAQRTMLLDALAAMKGVKAWKSDANMILVRVPDAAKTFEGMKSRH
VLVKNVSKMHPLLANCLRLTVGTADENTQMLAALEKSL

Sequences:

>Translated_358_residues
MTALDPKFKQLIRQDVQSMHAYAIQDSVGMVKLDAMENPYRLPAALQAHLGQRLGALALNRYPDGRVNDLRQALADYARM
PEGFDIMLGNGSDELISLLAMACDVPGGSILAPLPGFVMYGMSAQLQGLKFTGVPLTADFELDEAAMLAAIAEHRPSIIY
LAYPNNPTANLWDDTVIEKIITAAPGLVVMDEAYQPFSSKSYIDRIARHSHVLLMRTLSKFGLAGVRIGYMMGPKALIAE
IDKVRPPYNISVLNYECALFALEHREVFAEQAAAVVAQRTMLLDALAAMKGVKAWKSDANMILVRVPDAAKTFEGMKSRH
VLVKNVSKMHPLLANCLRLTVGTADENTQMLAALEKSL
>Mature_357_residues
TALDPKFKQLIRQDVQSMHAYAIQDSVGMVKLDAMENPYRLPAALQAHLGQRLGALALNRYPDGRVNDLRQALADYARMP
EGFDIMLGNGSDELISLLAMACDVPGGSILAPLPGFVMYGMSAQLQGLKFTGVPLTADFELDEAAMLAAIAEHRPSIIYL
AYPNNPTANLWDDTVIEKIITAAPGLVVMDEAYQPFSSKSYIDRIARHSHVLLMRTLSKFGLAGVRIGYMMGPKALIAEI
DKVRPPYNISVLNYECALFALEHREVFAEQAAAVVAQRTMLLDALAAMKGVKAWKSDANMILVRVPDAAKTFEGMKSRHV
LVKNVSKMHPLLANCLRLTVGTADENTQMLAALEKSL

Specific function: Histidine biosynthesis; seventh step. [C]

COG id: COG0079

COG function: function code E; Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788332, Length=357, Percent_Identity=31.3725490196078, Blast_Score=139, Evalue=4e-34,
Organism=Saccharomyces cerevisiae, GI6322075, Length=382, Percent_Identity=29.0575916230367, Blast_Score=133, Evalue=6e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR005861
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.9 [H]

Molecular weight: Translated: 39201; Mature: 39070

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTALDPKFKQLIRQDVQSMHAYAIQDSVGMVKLDAMENPYRLPAALQAHLGQRLGALALN
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHC
RYPDGRVNDLRQALADYARMPEGFDIMLGNGSDELISLLAMACDVPGGSILAPLPGFVMY
CCCCCHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHCCCCCCEECCCCHHHHH
GMSAQLQGLKFTGVPLTADFELDEAAMLAAIAEHRPSIIYLAYPNNPTANLWDDTVIEKI
CCCHHCCCEEEECCCEEECCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHH
ITAAPGLVVMDEAYQPFSSKSYIDRIARHSHVLLMRTLSKFGLAGVRIGYMMGPKALIAE
HHHCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHCCHHHHHHH
IDKVRPPYNISVLNYECALFALEHREVFAEQAAAVVAQRTMLLDALAAMKGVKAWKSDAN
HHHCCCCCEEEEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
MILVRVPDAAKTFEGMKSRHVLVKNVSKMHPLLANCLRLTVGTADENTQMLAALEKSL
EEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure 
TALDPKFKQLIRQDVQSMHAYAIQDSVGMVKLDAMENPYRLPAALQAHLGQRLGALALN
CCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHC
RYPDGRVNDLRQALADYARMPEGFDIMLGNGSDELISLLAMACDVPGGSILAPLPGFVMY
CCCCCHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHCCCCCCEECCCCHHHHH
GMSAQLQGLKFTGVPLTADFELDEAAMLAAIAEHRPSIIYLAYPNNPTANLWDDTVIEKI
CCCHHCCCEEEECCCEEECCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHH
ITAAPGLVVMDEAYQPFSSKSYIDRIARHSHVLLMRTLSKFGLAGVRIGYMMGPKALIAE
HHHCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHCCHHHHHHH
IDKVRPPYNISVLNYECALFALEHREVFAEQAAAVVAQRTMLLDALAAMKGVKAWKSDAN
HHHCCCCCEEEEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
MILVRVPDAAKTFEGMKSRHVLVKNVSKMHPLLANCLRLTVGTADENTQMLAALEKSL
EEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA