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The map label for this gene is manD [H]

Identifier: 91212557

GI number: 91212557

Start: 3505694

End: 3506848

Strand: Direct

Name: manD [H]

Synonym: UTI89_C3566

Alternate gene names: 91212557

Gene position: 3505694-3506848 (Clockwise)

Preceding gene: 91212556

Following gene: 91212558

Centisome position: 69.2

GC content: 57.92

Gene sequence:

>1155_bases
ATGTCCGGTCGAGGAAGGAATATGACACACGTTCTGCGCGCCAGAAGGCTGCTGACTGAAGAGGGATGGCTCGATGACCA
TCAGTTGCGTATTGCTGACGGTGTAATCGCAGCAATCGAACCGATTCCAGTGGGCGTGACTGAACGCGATGCGGAACTGC
TCTGTCCCGCTTACATCGACACCCATGTACACGGTGGTGCGGGCGTTGATGTAATGGATGACGCGCCGGATGTGCTCGAC
AAGCTGGCAATGCACAAAGCACGCGAAGGTGTCGGCAGTTGGTTACCGACCACCGTAACCGCGCCGCTTAATACCATTCA
TGCGGCGCTGGAACGTATTGCTCAACGTTGCCAACGCGGCGGACCTGGTGCGCAAGTGCTGGGGAGTTATCTCGAAGGAC
CGTACTTCACGCCGCAGAATAAAGGCGCGCATCCACCGGAGCTGTTCCGCGAGCTGGAAATTGCCGAGCTGGATCAATTG
ATTGCCGTTTCTCAGCATACCTTGCGCGTGGTGGCGCTGGCACCGGAAAAAGAAGGGGCATTGCAGGCCATCCGCCATCT
TAAACAGCAAAACGTACGGGTGATGCTGGGGCATAGCGCGGCGACCTGGCAACAAACCCGTGCCGCGTTTGATGCTGGTG
CCGACGGCCTGGTGCATTGCTATAACGGGATGACAGGTTTACATCACCGCGAACCGGGAATGGTTGGCGCGGGATTAACA
GACAAGCGCGCCTGGCTGGAACTGATAGCCGATGGTCATCATGTACATCCGGCGGCAATGTCGCTCTGTTGTTGCTGTGC
GAAAGAGAGGATCGTACTGATCACCGACGCGATGCAGGCAGCCGGGATGCCGGATGGTCACTATACGTTATGTGGTGAAG
AAGTGCAGATGCGCGGTGGCGTTGTCCGTACCGCGTCCGGTGGGCTGGCGGGCAGTACGCTGTCTGTCGATGCGGCAGTG
CGCAACATGGTCGAGTTGACGGGCGTAACGCCTGCGGAAGCCATCCATATGGCGTCGCTGCATCCGGCGCGAATGCTGGG
TGTTGATGGTGTTCTGGGATCGCTTAAACCGGGCAAACGCGCCAGCGTCGTTGCGCTGGATAGCGGGCTGCATGTGCAAC
AAATCTGGATTCAGGGTCAATTAGCTTCGTTTTGA

Upstream 100 bases:

>100_bases
GCGAAGGGTTAAGCGGTGAAGAGTTCCGTGTGCAGGCGCTGGAGTGTGGACACCGTGGGCTGACCAGTCTGGTGGACGAG
TTAGGCCGCTGCCATGAAGA

Downstream 100 bases:

>100_bases
TGGTTTGCTCCTTTATTAGGCCTTCACTTCCCCCGTAAGGCCTTCTTTTTCTTTCGTTTTGATCTGTGCAGCGGTGTCGG
ATGCGACGCTAATGCGTCTT

Product: putative N-acetylgalctosamine-6-phosphate deacetylase

Products: NA

Alternate protein names: GlcNAc 6-P deacetylase [H]

Number of amino acids: Translated: 384; Mature: 383

Protein sequence:

>384_residues
MSGRGRNMTHVLRARRLLTEEGWLDDHQLRIADGVIAAIEPIPVGVTERDAELLCPAYIDTHVHGGAGVDVMDDAPDVLD
KLAMHKAREGVGSWLPTTVTAPLNTIHAALERIAQRCQRGGPGAQVLGSYLEGPYFTPQNKGAHPPELFRELEIAELDQL
IAVSQHTLRVVALAPEKEGALQAIRHLKQQNVRVMLGHSAATWQQTRAAFDAGADGLVHCYNGMTGLHHREPGMVGAGLT
DKRAWLELIADGHHVHPAAMSLCCCCAKERIVLITDAMQAAGMPDGHYTLCGEEVQMRGGVVRTASGGLAGSTLSVDAAV
RNMVELTGVTPAEAIHMASLHPARMLGVDGVLGSLKPGKRASVVALDSGLHVQQIWIQGQLASF

Sequences:

>Translated_384_residues
MSGRGRNMTHVLRARRLLTEEGWLDDHQLRIADGVIAAIEPIPVGVTERDAELLCPAYIDTHVHGGAGVDVMDDAPDVLD
KLAMHKAREGVGSWLPTTVTAPLNTIHAALERIAQRCQRGGPGAQVLGSYLEGPYFTPQNKGAHPPELFRELEIAELDQL
IAVSQHTLRVVALAPEKEGALQAIRHLKQQNVRVMLGHSAATWQQTRAAFDAGADGLVHCYNGMTGLHHREPGMVGAGLT
DKRAWLELIADGHHVHPAAMSLCCCCAKERIVLITDAMQAAGMPDGHYTLCGEEVQMRGGVVRTASGGLAGSTLSVDAAV
RNMVELTGVTPAEAIHMASLHPARMLGVDGVLGSLKPGKRASVVALDSGLHVQQIWIQGQLASF
>Mature_383_residues
SGRGRNMTHVLRARRLLTEEGWLDDHQLRIADGVIAAIEPIPVGVTERDAELLCPAYIDTHVHGGAGVDVMDDAPDVLDK
LAMHKAREGVGSWLPTTVTAPLNTIHAALERIAQRCQRGGPGAQVLGSYLEGPYFTPQNKGAHPPELFRELEIAELDQLI
AVSQHTLRVVALAPEKEGALQAIRHLKQQNVRVMLGHSAATWQQTRAAFDAGADGLVHCYNGMTGLHHREPGMVGAGLTD
KRAWLELIADGHHVHPAAMSLCCCCAKERIVLITDAMQAAGMPDGHYTLCGEEVQMRGGVVRTASGGLAGSTLSVDAAVR
NMVELTGVTPAEAIHMASLHPARMLGVDGVLGSLKPGKRASVVALDSGLHVQQIWIQGQLASF

Specific function: N-acetylgalactosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Homo sapiens, GI21361513, Length=415, Percent_Identity=33.2530120481928, Blast_Score=191, Evalue=7e-49,
Organism=Homo sapiens, GI224922791, Length=415, Percent_Identity=33.0120481927711, Blast_Score=186, Evalue=2e-47,
Organism=Escherichia coli, GI1786892, Length=380, Percent_Identity=32.6315789473684, Blast_Score=183, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI17553768, Length=387, Percent_Identity=29.7157622739018, Blast_Score=156, Evalue=2e-38,
Organism=Drosophila melanogaster, GI19920392, Length=389, Percent_Identity=30.8483290488432, Blast_Score=181, Evalue=9e-46,
Organism=Drosophila melanogaster, GI281361140, Length=402, Percent_Identity=30.5970149253731, Blast_Score=176, Evalue=2e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR003764
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.1.25 [H]

Molecular weight: Translated: 41028; Mature: 40896

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGRGRNMTHVLRARRLLTEEGWLDDHQLRIADGVIAAIEPIPVGVTERDAELLCPAYID
CCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCEEEEECCCCCCCCCCCHHHCCHHHHH
THVHGGAGVDVMDDAPDVLDKLAMHKAREGVGSWLPTTVTAPLNTIHAALERIAQRCQRG
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCC
GPGAQVLGSYLEGPYFTPQNKGAHPPELFRELEIAELDQLIAVSQHTLRVVALAPEKEGA
CCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHCEEEEEEECCCCCHH
LQAIRHLKQQNVRVMLGHSAATWQQTRAAFDAGADGLVHCYNGMTGLHHREPGMVGAGLT
HHHHHHHHHCCCEEEECCCHHHHHHHHHHHHCCCCCCEEHHCCCCCCCCCCCCCEECCCC
DKRAWLELIADGHHVHPAAMSLCCCCAKERIVLITDAMQAAGMPDGHYTLCGEEVQMRGG
HHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEECCHHHCCCCCCCEEECCHHHHHCCC
VVRTASGGLAGSTLSVDAAVRNMVELTGVTPAEAIHMASLHPARMLGVDGVLGSLKPGKR
EEEECCCCCCCCEEEHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHCCCHHHCCCCCCCC
ASVVALDSGLHVQQIWIQGQLASF
EEEEEECCCCEEEEEEEECCCCCC
>Mature Secondary Structure 
SGRGRNMTHVLRARRLLTEEGWLDDHQLRIADGVIAAIEPIPVGVTERDAELLCPAYID
CCCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCEEEEECCCCCCCCCCCHHHCCHHHHH
THVHGGAGVDVMDDAPDVLDKLAMHKAREGVGSWLPTTVTAPLNTIHAALERIAQRCQRG
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCC
GPGAQVLGSYLEGPYFTPQNKGAHPPELFRELEIAELDQLIAVSQHTLRVVALAPEKEGA
CCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHCEEEEEEECCCCCHH
LQAIRHLKQQNVRVMLGHSAATWQQTRAAFDAGADGLVHCYNGMTGLHHREPGMVGAGLT
HHHHHHHHHCCCEEEECCCHHHHHHHHHHHHCCCCCCEEHHCCCCCCCCCCCCCEECCCC
DKRAWLELIADGHHVHPAAMSLCCCCAKERIVLITDAMQAAGMPDGHYTLCGEEVQMRGG
HHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEECCHHHCCCCCCCEEECCHHHHHCCC
VVRTASGGLAGSTLSVDAAVRNMVELTGVTPAEAIHMASLHPARMLGVDGVLGSLKPGKR
EEEECCCCCCCCEEEHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHCCCHHHCCCCCCCC
ASVVALDSGLHVQQIWIQGQLASF
EEEEEECCCCEEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969210 [H]