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The map label for this gene is kdsA [H]

Identifier: 89256819

GI number: 89256819

Start: 1464209

End: 1465036

Strand: Reverse

Name: kdsA [H]

Synonym: FTL_1535

Alternate gene names: 89256819

Gene position: 1465036-1464209 (Counterclockwise)

Preceding gene: 89256820

Following gene: 89256818

Centisome position: 77.27

GC content: 36.47

Gene sequence:

>828_bases
ATGAAAATTGCTAATTTTGAAGTAGGAAATGGTAAGCCATTTTTCTTAATGTCTGGTCCTTGTGTCATTGAATCTGAGCA
AATGGCGATGGATACTGCTGGATATCTTGCTGAGGTAACTAAGGATCTTGGAATAAATTTTGTTTATAAGTCATCTTTTG
ATAAAGCAAATCGCTCATCTATAAATAGCTTTAGAGGGCTAGGTGTAGATAAAGGTCTTGAAATTTTGGCTAAGGTCAAA
AAGACTTATAATGTGCCTGTCGTTACAGATGTCCATGAAGATACACCCTTTGCTGAGGTTGCTGAAGTTGTTGATGTATT
ACAAATTCCTGCTTTTTTATGCCGTCAAACAAACTTTATTCTTGAGGTCTGTAAGCAAGGAAAACCTGTAAATATCAAAA
AGGGTCAGTTTCTTGCACCTTGGGATATGCAGCATGTAGTAACAAAAGCTAAATCTACAGGCAATGAGCAGATTATGGTT
TGCGAAAGAGGTGTAAGCTTTGGTTATAATAATCTAGTTTCAGATATGCGTTCACTTGAGATTATGAAAGCTACAGGATG
TCCGGTAGTATTTGATGCTACTCATTCAGTGCAATTACCAGGAGGACAAGGTAGTTCTTCTGGTGGGCAGAGAGAGTTTG
TACCAGTTTTATCAAAAGCAGCTATGGCTGTTGGTATAGATGGACTTTTTATGGAAACTCATCCAAATCCTGATGAGGCA
AAAAGTGATGGACCTAATTCGTTCCCAATGTATAAAATAAAAGAATTTTTAAGTTTGCTAAAAGAGCTTGATCATTTAGT
AAAAAGTCAACCAAAGACAGAACTATAG

Upstream 100 bases:

>100_bases
TGCATACTTTGTAATTAGAAATCCAAATGCGAAAACTACTTGTGGCTGTGGTTCATCTTTTTCTGTATAATTATCACAAG
TGTATTTAAATAAAAATCTT

Downstream 100 bases:

>100_bases
GGCATAAATAATGGCTGGTAAAGGCGATGTTTTTATAATAGGTATAGTTGGTGGTTCTGGTTCTGGTAAAACATTATTTT
CAAATGCTATCATCAAAAAA

Product: 2-dehydro-3-deoxyphosphooctonate aldolase

Products: NA

Alternate protein names: 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase; KDO-8-phosphate synthase; KDO 8-P synthase; KDOPS; Phospho-2-dehydro-3-deoxyoctonate aldolase [H]

Number of amino acids: Translated: 275; Mature: 275

Protein sequence:

>275_residues
MKIANFEVGNGKPFFLMSGPCVIESEQMAMDTAGYLAEVTKDLGINFVYKSSFDKANRSSINSFRGLGVDKGLEILAKVK
KTYNVPVVTDVHEDTPFAEVAEVVDVLQIPAFLCRQTNFILEVCKQGKPVNIKKGQFLAPWDMQHVVTKAKSTGNEQIMV
CERGVSFGYNNLVSDMRSLEIMKATGCPVVFDATHSVQLPGGQGSSSGGQREFVPVLSKAAMAVGIDGLFMETHPNPDEA
KSDGPNSFPMYKIKEFLSLLKELDHLVKSQPKTEL

Sequences:

>Translated_275_residues
MKIANFEVGNGKPFFLMSGPCVIESEQMAMDTAGYLAEVTKDLGINFVYKSSFDKANRSSINSFRGLGVDKGLEILAKVK
KTYNVPVVTDVHEDTPFAEVAEVVDVLQIPAFLCRQTNFILEVCKQGKPVNIKKGQFLAPWDMQHVVTKAKSTGNEQIMV
CERGVSFGYNNLVSDMRSLEIMKATGCPVVFDATHSVQLPGGQGSSSGGQREFVPVLSKAAMAVGIDGLFMETHPNPDEA
KSDGPNSFPMYKIKEFLSLLKELDHLVKSQPKTEL
>Mature_275_residues
MKIANFEVGNGKPFFLMSGPCVIESEQMAMDTAGYLAEVTKDLGINFVYKSSFDKANRSSINSFRGLGVDKGLEILAKVK
KTYNVPVVTDVHEDTPFAEVAEVVDVLQIPAFLCRQTNFILEVCKQGKPVNIKKGQFLAPWDMQHVVTKAKSTGNEQIMV
CERGVSFGYNNLVSDMRSLEIMKATGCPVVFDATHSVQLPGGQGSSSGGQREFVPVLSKAAMAVGIDGLFMETHPNPDEA
KSDGPNSFPMYKIKEFLSLLKELDHLVKSQPKTEL

Specific function: Synthesis Of Kdo 8-P Which Is Required For Lipid A Maturation And Cellular Growth. [C]

COG id: COG2877

COG function: function code M; 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsA family [H]

Homologues:

Organism=Escherichia coli, GI1787466, Length=270, Percent_Identity=46.6666666666667, Blast_Score=263, Evalue=1e-71,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006269 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.55 [H]

Molecular weight: Translated: 30118; Mature: 30118

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIANFEVGNGKPFFLMSGPCVIESEQMAMDTAGYLAEVTKDLGINFVYKSSFDKANRSS
CCCCCEECCCCCEEEEECCCEEEECHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHH
INSFRGLGVDKGLEILAKVKKTYNVPVVTDVHEDTPFAEVAEVVDVLQIPAFLCRQTNFI
HHHHHCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LEVCKQGKPVNIKKGQFLAPWDMQHVVTKAKSTGNEQIMVCERGVSFGYNNLVSDMRSLE
HHHHHCCCCCCCCCCCEECCCCHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHH
IMKATGCPVVFDATHSVQLPGGQGSSSGGQREFVPVLSKAAMAVGIDGLFMETHPNPDEA
HHHCCCCCEEEECCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCC
KSDGPNSFPMYKIKEFLSLLKELDHLVKSQPKTEL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKIANFEVGNGKPFFLMSGPCVIESEQMAMDTAGYLAEVTKDLGINFVYKSSFDKANRSS
CCCCCEECCCCCEEEEECCCEEEECHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHH
INSFRGLGVDKGLEILAKVKKTYNVPVVTDVHEDTPFAEVAEVVDVLQIPAFLCRQTNFI
HHHHHCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LEVCKQGKPVNIKKGQFLAPWDMQHVVTKAKSTGNEQIMVCERGVSFGYNNLVSDMRSLE
HHHHHCCCCCCCCCCCEECCCCHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHH
IMKATGCPVVFDATHSVQLPGGQGSSSGGQREFVPVLSKAAMAVGIDGLFMETHPNPDEA
HHHCCCCCEEEECCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCC
KSDGPNSFPMYKIKEFLSLLKELDHLVKSQPKTEL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA