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The map label for this gene is erpA [H]

Identifier: 89256820

GI number: 89256820

Start: 1465067

End: 1465417

Strand: Reverse

Name: erpA [H]

Synonym: FTL_1536

Alternate gene names: 89256820

Gene position: 1465417-1465067 (Counterclockwise)

Preceding gene: 89256821

Following gene: 89256819

Centisome position: 77.29

GC content: 36.75

Gene sequence:

>351_bases
ATGAGTGAAGTAGTTCAAAGCGTTGATCCGATAAACTTTACAGAAGCCGCTTCTTTAAAGGTTAAAGAACTAATTGAAGA
GGAGGGTGATAATTCTCTTAGCCTTAGAGTATACATCACCGGTGGGGGCTGTTCTGGGTTTCAATATGCTTTTGCTTTTG
ATAATGAAGTAAAAGAAGATGATATGGTTATTACTAAAAATGGTGTTCGCCTTTTGGTAGATTCTATGAGTTTTCAGTAC
TTGGTTGGTGCTGATGTTGACTACAAAGATGATGTCGAAGGTGCATACTTTGTAATTAGAAATCCAAATGCGAAAACTAC
TTGTGGCTGTGGTTCATCTTTTTCTGTATAA

Upstream 100 bases:

>100_bases
AAACTAACTCGTTAGTAGAAGGTCAAGGATTAGAAGTTTTAGTTCAAAATATCGATAGAGGTGGTAGAGTTAAACTTTCT
CTTGTAGCGAGGTAATTATT

Downstream 100 bases:

>100_bases
TTATCACAAGTGTATTTAAATAAAAATCTTATGAAAATTGCTAATTTTGAAGTAGGAAATGGTAAGCCATTTTTCTTAAT
GTCTGGTCCTTGTGTCATTG

Product: iron-sulfur cluster insertion protein ErpA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 116; Mature: 115

Protein sequence:

>116_residues
MSEVVQSVDPINFTEAASLKVKELIEEEGDNSLSLRVYITGGGCSGFQYAFAFDNEVKEDDMVITKNGVRLLVDSMSFQY
LVGADVDYKDDVEGAYFVIRNPNAKTTCGCGSSFSV

Sequences:

>Translated_116_residues
MSEVVQSVDPINFTEAASLKVKELIEEEGDNSLSLRVYITGGGCSGFQYAFAFDNEVKEDDMVITKNGVRLLVDSMSFQY
LVGADVDYKDDVEGAYFVIRNPNAKTTCGCGSSFSV
>Mature_115_residues
SEVVQSVDPINFTEAASLKVKELIEEEGDNSLSLRVYITGGGCSGFQYAFAFDNEVKEDDMVITKNGVRLLVDSMSFQYL
VGADVDYKDDVEGAYFVIRNPNAKTTCGCGSSFSV

Specific function: Required for insertion of 4Fe-4S clusters for at least ispG [H]

COG id: COG0316

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesB/iscA family [H]

Homologues:

Organism=Homo sapiens, GI160420328, Length=107, Percent_Identity=39.2523364485981, Blast_Score=86, Evalue=9e-18,
Organism=Homo sapiens, GI52426768, Length=106, Percent_Identity=30.188679245283, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1786351, Length=107, Percent_Identity=63.5514018691589, Blast_Score=148, Evalue=9e-38,
Organism=Escherichia coli, GI1788877, Length=106, Percent_Identity=33.9622641509434, Blast_Score=70, Evalue=4e-14,
Organism=Escherichia coli, GI1787974, Length=106, Percent_Identity=29.2452830188679, Blast_Score=67, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71998452, Length=108, Percent_Identity=37.037037037037, Blast_Score=82, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI25146411, Length=114, Percent_Identity=28.9473684210526, Blast_Score=72, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI193209025, Length=106, Percent_Identity=29.2452830188679, Blast_Score=70, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6323001, Length=82, Percent_Identity=39.0243902439024, Blast_Score=73, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24649697, Length=83, Percent_Identity=42.1686746987952, Blast_Score=79, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24642263, Length=114, Percent_Identity=29.8245614035088, Blast_Score=72, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000361
- InterPro:   IPR016092
- InterPro:   IPR017870
- InterPro:   IPR023063 [H]

Pfam domain/function: PF01521 Fe-S_biosyn [H]

EC number: NA

Molecular weight: Translated: 12658; Mature: 12527

Theoretical pI: Translated: 3.98; Mature: 3.98

Prosite motif: PS01152 HESB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEVVQSVDPINFTEAASLKVKELIEEEGDNSLSLRVYITGGGCSGFQYAFAFDNEVKED
CCCHHHHCCCCCCCCCCCHHHHHHHHHCCCCEEEEEEEEECCCCCCEEEEEEECCCCCCC
DMVITKNGVRLLVDSMSFQYLVGADVDYKDDVEGAYFVIRNPNAKTTCGCGSSFSV
CEEEECCCEEEEEECCCEEEEEECCCCCCCCCCEEEEEEECCCCCCEECCCCCCCC
>Mature Secondary Structure 
SEVVQSVDPINFTEAASLKVKELIEEEGDNSLSLRVYITGGGCSGFQYAFAFDNEVKED
CCHHHHCCCCCCCCCCCHHHHHHHHHCCCCEEEEEEEEECCCCCCEEEEEEECCCCCCC
DMVITKNGVRLLVDSMSFQYLVGADVDYKDDVEGAYFVIRNPNAKTTCGCGSSFSV
CEEEECCCEEEEEECCCEEEEEECCCCCCCCCCEEEEEEECCCCCCEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA