Click here to switch to the map view.

The map label for this gene is galE [H]

Identifier: 89256723

GI number: 89256723

Start: 1360796

End: 1361815

Strand: Reverse

Name: galE [H]

Synonym: FTL_1430

Alternate gene names: 89256723

Gene position: 1361815-1360796 (Counterclockwise)

Preceding gene: 89256724

Following gene: 89256722

Centisome position: 71.83

GC content: 34.8

Gene sequence:

>1020_bases
ATGAATAAAAAAATCTTAGTAACAGGTGGTGTAGGCTATATAGGTAGTCATACAGTGGTAGAACTTCTTGATAGAGATTA
TCAAGTTGTGGTGGTAGATAATCTTTCAAATAGCAAAGTATCTGTAATAGACAGGGTTAAAAAAATCACAAATAAAGATT
TTGATTTTTATCAGCTAGACCTTTTAGGTAAAGCTAAGCTAACAAAAGTTTTTCAAGAGCATGATATTTATGCTGTAATT
CATTTTGCTGGCTTTAAAGCTGTAGGTGAGAGTGTTGAAAAACCGTTAGAGTATTATCATAACAATATCCAAGGTACACT
AAACTTACTTGAGCTAATGCAAGAGTATAAAGTTTATAATTTTGTCTTTAGTTCATCAGCGACTGTATATGGGATGAATA
ATAAACCACCCTTTACAGAAGATATGCCTCTAAGTACAACTAACCCATACGGTGCAACTAAGCTAATGTTAGAAGACATT
TTGCGAGATTTGCAAAATGCTAATAATAATTTTAATATTACATGTCTTAGATATTTTAATCCAGTCGGAGCCCATAGTAG
TGGGATGATAGGAGAGGATCCACAGGGTATACCTAATAACCTCATGCCTTATGTCGCGCAAGTAGGTGCTGGTAAACTAG
CTAAACTTAGTATCTTTGGTGGTGACTATGAGACTATAGATGGTACGGGAGTGAGAGACTATATACATGTTGTAGATTTA
GCAATAGGTCATATATTAGCGTTAGAAAAATTATCACAAGATAAGCCTAGCTGGAGAGCTTATAATCTTGGTTCTGGAAA
TGGCTATTCTGTATTAGAGATTGTCAAAGCTTATCAAAAAGCCCTAGGTAAAGAGATTCCATATCAGATAGTAGCTAGGA
GAACCGGTGATATTGCAGCGAGTTTTGCTGATGTTGCCAAGGCTAAAAGAGAGTTGGGTTTTGAGACACAAAAGACTATA
GATGATATTTGTGATGATATGCTTAAATGGCAAAAGTACGCAAAAGAGAATAATATCTAG

Upstream 100 bases:

>100_bases
GTTATTGCTATGAAAATTTTGCGACTATTTATAAAAACTAAAGAGCAATCTCAAGCAAGTTTTGTAGAGAAAAAACACAA
AAACTATACAGAGTATATTT

Downstream 100 bases:

>100_bases
AAAATGAAAATCTTACATGTGTTTAAGTCATTTTATCCATATACTTATGGTGGTATAGAGAAGTTTATACATGAGCTATC
GATTGCTACGGCTAAAAAGT

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MNKKILVTGGVGYIGSHTVVELLDRDYQVVVVDNLSNSKVSVIDRVKKITNKDFDFYQLDLLGKAKLTKVFQEHDIYAVI
HFAGFKAVGESVEKPLEYYHNNIQGTLNLLELMQEYKVYNFVFSSSATVYGMNNKPPFTEDMPLSTTNPYGATKLMLEDI
LRDLQNANNNFNITCLRYFNPVGAHSSGMIGEDPQGIPNNLMPYVAQVGAGKLAKLSIFGGDYETIDGTGVRDYIHVVDL
AIGHILALEKLSQDKPSWRAYNLGSGNGYSVLEIVKAYQKALGKEIPYQIVARRTGDIAASFADVAKAKRELGFETQKTI
DDICDDMLKWQKYAKENNI

Sequences:

>Translated_339_residues
MNKKILVTGGVGYIGSHTVVELLDRDYQVVVVDNLSNSKVSVIDRVKKITNKDFDFYQLDLLGKAKLTKVFQEHDIYAVI
HFAGFKAVGESVEKPLEYYHNNIQGTLNLLELMQEYKVYNFVFSSSATVYGMNNKPPFTEDMPLSTTNPYGATKLMLEDI
LRDLQNANNNFNITCLRYFNPVGAHSSGMIGEDPQGIPNNLMPYVAQVGAGKLAKLSIFGGDYETIDGTGVRDYIHVVDL
AIGHILALEKLSQDKPSWRAYNLGSGNGYSVLEIVKAYQKALGKEIPYQIVARRTGDIAASFADVAKAKRELGFETQKTI
DDICDDMLKWQKYAKENNI
>Mature_339_residues
MNKKILVTGGVGYIGSHTVVELLDRDYQVVVVDNLSNSKVSVIDRVKKITNKDFDFYQLDLLGKAKLTKVFQEHDIYAVI
HFAGFKAVGESVEKPLEYYHNNIQGTLNLLELMQEYKVYNFVFSSSATVYGMNNKPPFTEDMPLSTTNPYGATKLMLEDI
LRDLQNANNNFNITCLRYFNPVGAHSSGMIGEDPQGIPNNLMPYVAQVGAGKLAKLSIFGGDYETIDGTGVRDYIHVVDL
AIGHILALEKLSQDKPSWRAYNLGSGNGYSVLEIVKAYQKALGKEIPYQIVARRTGDIAASFADVAKAKRELGFETQKTI
DDICDDMLKWQKYAKENNI

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=339, Percent_Identity=53.9823008849557, Blast_Score=378, Evalue=1e-105,
Organism=Homo sapiens, GI56118217, Length=339, Percent_Identity=53.9823008849557, Blast_Score=378, Evalue=1e-105,
Organism=Homo sapiens, GI189083684, Length=339, Percent_Identity=53.9823008849557, Blast_Score=378, Evalue=1e-105,
Organism=Homo sapiens, GI7657641, Length=278, Percent_Identity=26.6187050359712, Blast_Score=89, Evalue=8e-18,
Organism=Homo sapiens, GI193211614, Length=257, Percent_Identity=28.4046692607004, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI8393516, Length=257, Percent_Identity=28.4046692607004, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI42516563, Length=318, Percent_Identity=23.5849056603774, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI1786974, Length=330, Percent_Identity=54.5454545454545, Blast_Score=370, Evalue=1e-104,
Organism=Escherichia coli, GI48994969, Length=363, Percent_Identity=26.1707988980716, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1788353, Length=367, Percent_Identity=26.158038147139, Blast_Score=86, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI71982038, Length=339, Percent_Identity=49.8525073746313, Blast_Score=337, Evalue=4e-93,
Organism=Caenorhabditis elegans, GI71982035, Length=336, Percent_Identity=49.4047619047619, Blast_Score=335, Evalue=2e-92,
Organism=Caenorhabditis elegans, GI115532424, Length=338, Percent_Identity=26.3313609467456, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17568069, Length=343, Percent_Identity=24.4897959183673, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6319493, Length=337, Percent_Identity=54.0059347181009, Blast_Score=362, Evalue=1e-101,
Organism=Drosophila melanogaster, GI19923002, Length=335, Percent_Identity=52.5373134328358, Blast_Score=360, Evalue=1e-100,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040
- InterPro:   IPR008089 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 37847; Mature: 37847

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKKILVTGGVGYIGSHTVVELLDRDYQVVVVDNLSNSKVSVIDRVKKITNKDFDFYQLD
CCCCEEEECCCCCCCHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCEEEEE
LLGKAKLTKVFQEHDIYAVIHFAGFKAVGESVEKPLEYYHNNIQGTLNLLELMQEYKVYN
ECCHHHHHHHHHHCCEEEEEEEHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
FVFSSSATVYGMNNKPPFTEDMPLSTTNPYGATKLMLEDILRDLQNANNNFNITCLRYFN
EEEECCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEECC
PVGAHSSGMIGEDPQGIPNNLMPYVAQVGAGKLAKLSIFGGDYETIDGTGVRDYIHVVDL
CCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHH
AIGHILALEKLSQDKPSWRAYNLGSGNGYSVLEIVKAYQKALGKEIPYQIVARRTGDIAA
HHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHCCCHHHH
SFADVAKAKRELGFETQKTIDDICDDMLKWQKYAKENNI
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNKKILVTGGVGYIGSHTVVELLDRDYQVVVVDNLSNSKVSVIDRVKKITNKDFDFYQLD
CCCCEEEECCCCCCCHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCEEEEE
LLGKAKLTKVFQEHDIYAVIHFAGFKAVGESVEKPLEYYHNNIQGTLNLLELMQEYKVYN
ECCHHHHHHHHHHCCEEEEEEEHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
FVFSSSATVYGMNNKPPFTEDMPLSTTNPYGATKLMLEDILRDLQNANNNFNITCLRYFN
EEEECCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEECC
PVGAHSSGMIGEDPQGIPNNLMPYVAQVGAGKLAKLSIFGGDYETIDGTGVRDYIHVVDL
CCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHH
AIGHILALEKLSQDKPSWRAYNLGSGNGYSVLEIVKAYQKALGKEIPYQIVARRTGDIAA
HHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHCCCHHHH
SFADVAKAKRELGFETQKTIDDICDDMLKWQKYAKENNI
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8978088; 8969509; 9384377 [H]