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The map label for this gene is nadA [H]

Identifier: 89256683

GI number: 89256683

Start: 1319886

End: 1320911

Strand: Reverse

Name: nadA [H]

Synonym: FTL_1390

Alternate gene names: 89256683

Gene position: 1320911-1319886 (Counterclockwise)

Preceding gene: 89256684

Following gene: 89256682

Centisome position: 69.67

GC content: 35.58

Gene sequence:

>1026_bases
ATGTTAAACAAAAAACTTATAAAAGATAAGATATCACAAGCTAGACAAGAATTACCTAGTTTGAAAATTAAAGATACTGA
AAAACAACAATATATGCGGGAAATTCAGGAGTTATTAGAACAAAATAATGCTTGTTTGGTAGCGCATTATTATGTTGATG
CAGAAATTCAAGAATTAGCTGAGAAAACTGGTGGATTTGTCGGTGATTCGCTTGCTATGGCGAAGTTTGGCTTAGAAAGC
AGCTGTGACACTTTAGTAGTTGCAGGAGTTAGATTTATGGGTGATTCCGCTAAGATTTTGAATCCCGAGAAAAAAATTCT
AATGCCAACTCTAGAAGCAGAGTGTTCGCTAGATTTAAGTTGTAGTAATGATGAGTTCAAAAAGTTTATAGAAGCTAATC
CTGATAGAGAAGTTGTGGTTTATGTCAATACAGCAGCAGAGATTAAAGCTCTAGCTGATTGGACAGTAACATCATCCAAT
GCTTTGGAGATTTGTTCACATCTACACAAGCAAGGTAAAAAGCTACTTTGGGGACCTGATAGATTTCTTGGTGATTGGAT
TGCTAAGCAAACTGGTGCAGATATGTTGCTGTATGACGGTAGTTGTATAGTACATGAGGAGTTTAAAGCTCAAGCGCTAG
ATGATTTAATACTAGAACATCCAGATGCTGCAGTTTTAGTACATCCTGAATCACCAGCAGAAATTATCAAAAGAGCAGAT
GCAGTTGGTTCAACATCTCAACTAATAGCAGCAAGCCAAAGACTTAGCAATACAAAATTTATTGTTGCTACAGATACGGG
TGTATTTTATAAAATGAAACAGCTATCACCACATAAAGAGTTTATCCCAGCGCCTACTGCTGGTCGTGGTGCAACATGTC
AATCATGTGCAAAATGCCCTTGGATGAAACTAAATCAACTTAAAAATCTAAAAGATTGTTTAATTAATCAGACTAACGAA
ATATTTATTGATGAAGAAGTAAGACAAAAGGCGCTTATCCCATTAAATAGGATGATAAATTTCTAG

Upstream 100 bases:

>100_bases
ATTATCTGCTGGTTAACGATGATTTTAGCCAGTCATTAGAACAATTATGTAAATATTTCGAACAAAATATCCAAAGTTAA
AGGCTAAGGAGAACATTTGG

Downstream 100 bases:

>100_bases
GAAATAGTATGGCTGATGTGATGTTGAATACTGACCAAATTAACAAAGTTCCCAATGATATTATTACAAGACTAGTTAGA
GAGTCTTTGGCAGAAGATAT

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 341; Mature: 341

Protein sequence:

>341_residues
MLNKKLIKDKISQARQELPSLKIKDTEKQQYMREIQELLEQNNACLVAHYYVDAEIQELAEKTGGFVGDSLAMAKFGLES
SCDTLVVAGVRFMGDSAKILNPEKKILMPTLEAECSLDLSCSNDEFKKFIEANPDREVVVYVNTAAEIKALADWTVTSSN
ALEICSHLHKQGKKLLWGPDRFLGDWIAKQTGADMLLYDGSCIVHEEFKAQALDDLILEHPDAAVLVHPESPAEIIKRAD
AVGSTSQLIAASQRLSNTKFIVATDTGVFYKMKQLSPHKEFIPAPTAGRGATCQSCAKCPWMKLNQLKNLKDCLINQTNE
IFIDEEVRQKALIPLNRMINF

Sequences:

>Translated_341_residues
MLNKKLIKDKISQARQELPSLKIKDTEKQQYMREIQELLEQNNACLVAHYYVDAEIQELAEKTGGFVGDSLAMAKFGLES
SCDTLVVAGVRFMGDSAKILNPEKKILMPTLEAECSLDLSCSNDEFKKFIEANPDREVVVYVNTAAEIKALADWTVTSSN
ALEICSHLHKQGKKLLWGPDRFLGDWIAKQTGADMLLYDGSCIVHEEFKAQALDDLILEHPDAAVLVHPESPAEIIKRAD
AVGSTSQLIAASQRLSNTKFIVATDTGVFYKMKQLSPHKEFIPAPTAGRGATCQSCAKCPWMKLNQLKNLKDCLINQTNE
IFIDEEVRQKALIPLNRMINF
>Mature_341_residues
MLNKKLIKDKISQARQELPSLKIKDTEKQQYMREIQELLEQNNACLVAHYYVDAEIQELAEKTGGFVGDSLAMAKFGLES
SCDTLVVAGVRFMGDSAKILNPEKKILMPTLEAECSLDLSCSNDEFKKFIEANPDREVVVYVNTAAEIKALADWTVTSSN
ALEICSHLHKQGKKLLWGPDRFLGDWIAKQTGADMLLYDGSCIVHEEFKAQALDDLILEHPDAAVLVHPESPAEIIKRAD
AVGSTSQLIAASQRLSNTKFIVATDTGVFYKMKQLSPHKEFIPAPTAGRGATCQSCAKCPWMKLNQLKNLKDCLINQTNE
IFIDEEVRQKALIPLNRMINF

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=317, Percent_Identity=58.3596214511041, Blast_Score=399, Evalue=1e-112,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 38047; Mature: 38047

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNKKLIKDKISQARQELPSLKIKDTEKQQYMREIQELLEQNNACLVAHYYVDAEIQELA
CCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEECHHHHHHH
EKTGGFVGDSLAMAKFGLESSCDTLVVAGVRFMGDSAKILNPEKKILMPTLEAECSLDLS
HHHCCCCCCHHHHHHHCCCCCCCHHEEHHHHHCCCCCHHCCCCHHEEEEECCCCCCEEEC
CSNDEFKKFIEANPDREVVVYVNTAAEIKALADWTVTSSNALEICSHLHKQGKKLLWGPD
CCCHHHHHHHHCCCCCEEEEEEECHHHHHHHHCEEECCCCHHHHHHHHHHCCCEEECCCH
RFLGDWIAKQTGADMLLYDGSCIVHEEFKAQALDDLILEHPDAAVLVHPESPAEIIKRAD
HHHHHHHHHHCCCCEEEECCCEEEEHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHH
AVGSTSQLIAASQRLSNTKFIVATDTGVFYKMKQLSPHKEFIPAPTAGRGATCQSCAKCP
CCCCHHHHHHHHHHCCCCEEEEEECCCCEEEEHHCCCCHHCCCCCCCCCCCCHHHHHCCC
WMKLNQLKNLKDCLINQTNEIFIDEEVRQKALIPLNRMINF
CHHHHHHHHHHHHHCCCCCCEEECHHHHHHHHCCHHHHCCC
>Mature Secondary Structure
MLNKKLIKDKISQARQELPSLKIKDTEKQQYMREIQELLEQNNACLVAHYYVDAEIQELA
CCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEECHHHHHHH
EKTGGFVGDSLAMAKFGLESSCDTLVVAGVRFMGDSAKILNPEKKILMPTLEAECSLDLS
HHHCCCCCCHHHHHHHCCCCCCCHHEEHHHHHCCCCCHHCCCCHHEEEEECCCCCCEEEC
CSNDEFKKFIEANPDREVVVYVNTAAEIKALADWTVTSSNALEICSHLHKQGKKLLWGPD
CCCHHHHHHHHCCCCCEEEEEEECHHHHHHHHCEEECCCCHHHHHHHHHHCCCEEECCCH
RFLGDWIAKQTGADMLLYDGSCIVHEEFKAQALDDLILEHPDAAVLVHPESPAEIIKRAD
HHHHHHHHHHCCCCEEEECCCEEEEHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHH
AVGSTSQLIAASQRLSNTKFIVATDTGVFYKMKQLSPHKEFIPAPTAGRGATCQSCAKCP
CCCCHHHHHHHHHHCCCCEEEEEECCCCEEEEHHCCCCHHCCCCCCCCCCCCHHHHHCCC
WMKLNQLKNLKDCLINQTNEIFIDEEVRQKALIPLNRMINF
CHHHHHHHHHHHHHCCCCCCEEECHHHHHHHHCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA