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The map label for this gene is coaD

Identifier: 89256634

GI number: 89256634

Start: 1265890

End: 1266378

Strand: Reverse

Name: coaD

Synonym: FTL_1330

Alternate gene names: 89256634

Gene position: 1266378-1265890 (Counterclockwise)

Preceding gene: 89256635

Following gene: 89256633

Centisome position: 66.79

GC content: 32.52

Gene sequence:

>489_bases
ATGAATAAGATAGCAATTTATCCAGGTACTTTTGACCCAATTACCAATGGTCATGTTGATCTAGTAGAGCGTGCATTAAA
TATCTTTGATGAAATAGTTGTTGCAGTATCTACAGCTTATGGTAAAAATACTCTTTTTGATATTCGTATCAGAGAGCAAA
TGATAAAAGAAGTATTCAAAGATAATCAAAGGGTCAAAGTTGTAAGCTTTCAGGGTCTACTTGTTGATACAGCAGTCAAA
CATAATGCTTGTGCTATAGTTAGAGGTCTCAGAGCAGTATCTGATTTTGATTATGAATTTCAGATGTCAAGTATGAATAA
TAAATTAAACAGTGATATTCAAACTATATTCTTAACTCCGAGTGAGAAGTTTTCATGTATTTCCTCGACATTAGTTAGGG
CTGTAGCGATACATAATTATAAGCGTGTTGATGAGTTTGTACCTGAATGTGTCTTTCGTGAGATAAAGCTTAAATATTCT
AAGGAATAA

Upstream 100 bases:

>100_bases
ATAAAGTTGATGTAGTAATGGTTTTTGATCCGCCATGGAATTCAGAAATGATGACTGAAGCTGCTAAGTTAGAGTTAGGT
TTATTTTAGTAATTTAGCTT

Downstream 100 bases:

>100_bases
AATTATGGCATTATTAATTACTGATGAATGTATTAATTGTGATATTTGTGAGCCTGAATGCCCTAATGAGGCAATATCAC
AAGGTGAAGAGTATTATGAG

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT

Number of amino acids: Translated: 162; Mature: 162

Protein sequence:

>162_residues
MNKIAIYPGTFDPITNGHVDLVERALNIFDEIVVAVSTAYGKNTLFDIRIREQMIKEVFKDNQRVKVVSFQGLLVDTAVK
HNACAIVRGLRAVSDFDYEFQMSSMNNKLNSDIQTIFLTPSEKFSCISSTLVRAVAIHNYKRVDEFVPECVFREIKLKYS
KE

Sequences:

>Translated_162_residues
MNKIAIYPGTFDPITNGHVDLVERALNIFDEIVVAVSTAYGKNTLFDIRIREQMIKEVFKDNQRVKVVSFQGLLVDTAVK
HNACAIVRGLRAVSDFDYEFQMSSMNNKLNSDIQTIFLTPSEKFSCISSTLVRAVAIHNYKRVDEFVPECVFREIKLKYS
KE
>Mature_162_residues
MNKIAIYPGTFDPITNGHVDLVERALNIFDEIVVAVSTAYGKNTLFDIRIREQMIKEVFKDNQRVKVVSFQGLLVDTAVK
HNACAIVRGLRAVSDFDYEFQMSSMNNKLNSDIQTIFLTPSEKFSCISSTLVRAVAIHNYKRVDEFVPECVFREIKLKYS
KE

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family

Homologues:

Organism=Escherichia coli, GI1790065, Length=160, Percent_Identity=41.25, Blast_Score=140, Evalue=4e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAD_FRAT1 (Q14IN9)

Other databases:

- EMBL:   AM286280
- RefSeq:   YP_666737.1
- ProteinModelPortal:   Q14IN9
- SMR:   Q14IN9
- STRING:   Q14IN9
- GeneID:   4200270
- GenomeReviews:   AM286280_GR
- KEGG:   ftf:FTF0581
- eggNOG:   COG0669
- HOGENOM:   HBG288308
- OMA:   VRQIAAM
- PhylomeDB:   Q14IN9
- ProtClustDB:   PRK00168
- BioCyc:   FTUL393115:FTF0581-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00151
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PRINTS:   PR01020
- TIGRFAMs:   TIGR01510
- TIGRFAMs:   TIGR00125

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.3

Molecular weight: Translated: 18518; Mature: 18518

Theoretical pI: Translated: 8.05; Mature: 8.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKIAIYPGTFDPITNGHVDLVERALNIFDEIVVAVSTAYGKNTLFDIRIREQMIKEVFK
CCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHC
DNQRVKVVSFQGLLVDTAVKHNACAIVRGLRAVSDFDYEFQMSSMNNKLNSDIQTIFLTP
CCCEEEEEEECCEEEHHHHCCCHHHHHHHHHHHHCCCCEEEHHHHCCCCCCCEEEEEECC
SEKFSCISSTLVRAVAIHNYKRVDEFVPECVFREIKLKYSKE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNKIAIYPGTFDPITNGHVDLVERALNIFDEIVVAVSTAYGKNTLFDIRIREQMIKEVFK
CCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHC
DNQRVKVVSFQGLLVDTAVKHNACAIVRGLRAVSDFDYEFQMSSMNNKLNSDIQTIFLTP
CCCEEEEEEECCEEEHHHHCCCHHHHHHHHHHHHCCCCEEEHHHHCCCCCCCEEEEEECC
SEKFSCISSTLVRAVAIHNYKRVDEFVPECVFREIKLKYSKE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA