The gene/protein map for NC_007880 is currently unavailable.
Definition Francisella tularensis subsp. holarctica LVS chromosome, complete genome.
Accession NC_007880
Length 1,895,994

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The map label for this gene is fabG [H]

Identifier: 89256563

GI number: 89256563

Start: 1190603

End: 1191310

Strand: Direct

Name: fabG [H]

Synonym: FTL_1245

Alternate gene names: 89256563

Gene position: 1190603-1191310 (Clockwise)

Preceding gene: 89256562

Following gene: 89256564

Centisome position: 62.8

GC content: 32.63

Gene sequence:

>708_bases
ATGTCTAATAGAATTGTTTTAATTACAGGTGCCACAAAAGGAATTGGATTAGCTACAAGCTTATATTTAAATAATCAAGG
ATGGCAAGTTATTGGAATAGCGAGATCATATATTGATAATTTCCCCGGAGAGTTGTTTTTATGTGACTTAGCTAATGAAG
AACAAACTGCCTCTACACTCATTCAAATAAATGAGATTCATGGATGTCCAGATGCAATTATTAATAATGTTGGAATAGCT
ATTCCAGAACCTTTGGGAAAAATTTCTATTTCAGCACTTAATGACGTCTATAATTTAAATGTTAGAAGTGCTGTACAAGT
ATCACAGTTTTTTATTGAAAAAATGAAACTAAAAGAACAATGCAAAATTGTTAATATTGCAAGTAGAGCTATCTTTGGAG
TTAAAAATCTTACAAGTTATTCCGCTGCAAAATCTGCTTTGGTTGGATGTACTAAAACTTGGGCTCTAGAGCTTGCTAAG
TATGGAATATGTGTAAATGCTATAGCTCCGGGTTCAGTAGATACTGAATTATTTAGAAAAACTAGACCTATTGGTAGTAG
TGAAGAAAAAGAAGTTTTAGATTCTATTCCTATGATGCGTATAGGGAAGCCTGAAGAAATAGCTGCAACAATAGCTTTCT
TATTATCAAACGAAGCATCTTTTATCATAGGACAAGTCATTTGTGTTGACGGTGGTGGAAGTTTATAA

Upstream 100 bases:

>100_bases
CAGAGTCTGATTATGTCTATAAAGAGAATTGGTTCTCAGATCATGCACCATTAACTATTAATTATGATTATGAGGTTTAA
TCTACCAAGGAGCTCTTAAA

Downstream 100 bases:

>100_bases
CAATGTACTATATTTATGTATTCTCAGGTTTGCCAGGAATAGGCAAAACAACTTTAGCTAAACAATTAGCTCAAGTTATA
CCTAATACGGCATACTTTAG

Product: short chain dehydrogenase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 235; Mature: 234

Protein sequence:

>235_residues
MSNRIVLITGATKGIGLATSLYLNNQGWQVIGIARSYIDNFPGELFLCDLANEEQTASTLIQINEIHGCPDAIINNVGIA
IPEPLGKISISALNDVYNLNVRSAVQVSQFFIEKMKLKEQCKIVNIASRAIFGVKNLTSYSAAKSALVGCTKTWALELAK
YGICVNAIAPGSVDTELFRKTRPIGSSEEKEVLDSIPMMRIGKPEEIAATIAFLLSNEASFIIGQVICVDGGGSL

Sequences:

>Translated_235_residues
MSNRIVLITGATKGIGLATSLYLNNQGWQVIGIARSYIDNFPGELFLCDLANEEQTASTLIQINEIHGCPDAIINNVGIA
IPEPLGKISISALNDVYNLNVRSAVQVSQFFIEKMKLKEQCKIVNIASRAIFGVKNLTSYSAAKSALVGCTKTWALELAK
YGICVNAIAPGSVDTELFRKTRPIGSSEEKEVLDSIPMMRIGKPEEIAATIAFLLSNEASFIIGQVICVDGGGSL
>Mature_234_residues
SNRIVLITGATKGIGLATSLYLNNQGWQVIGIARSYIDNFPGELFLCDLANEEQTASTLIQINEIHGCPDAIINNVGIAI
PEPLGKISISALNDVYNLNVRSAVQVSQFFIEKMKLKEQCKIVNIASRAIFGVKNLTSYSAAKSALVGCTKTWALELAKY
GICVNAIAPGSVDTELFRKTRPIGSSEEKEVLDSIPMMRIGKPEEIAATIAFLLSNEASFIIGQVICVDGGGSL

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI7705925, Length=241, Percent_Identity=30.7053941908714, Blast_Score=102, Evalue=4e-22,
Organism=Homo sapiens, GI109715829, Length=244, Percent_Identity=31.1475409836066, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI32483357, Length=248, Percent_Identity=26.2096774193548, Blast_Score=96, Evalue=2e-20,
Organism=Homo sapiens, GI40254992, Length=241, Percent_Identity=27.8008298755187, Blast_Score=90, Evalue=1e-18,
Organism=Homo sapiens, GI15277342, Length=259, Percent_Identity=28.1853281853282, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI19923817, Length=252, Percent_Identity=28.1746031746032, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI59889578, Length=207, Percent_Identity=28.5024154589372, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI66933014, Length=143, Percent_Identity=35.6643356643357, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI4503301, Length=189, Percent_Identity=30.1587301587302, Blast_Score=78, Evalue=6e-15,
Organism=Homo sapiens, GI5031737, Length=244, Percent_Identity=27.8688524590164, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI126723750, Length=249, Percent_Identity=24.4979919678715, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI7657478, Length=192, Percent_Identity=28.6458333333333, Blast_Score=71, Evalue=9e-13,
Organism=Homo sapiens, GI10190704, Length=249, Percent_Identity=26.1044176706827, Blast_Score=65, Evalue=5e-11,
Organism=Escherichia coli, GI1787335, Length=238, Percent_Identity=32.3529411764706, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1786812, Length=244, Percent_Identity=31.1475409836066, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1789208, Length=248, Percent_Identity=32.6612903225806, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1788459, Length=248, Percent_Identity=30.6451612903226, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI2367175, Length=250, Percent_Identity=30.8, Blast_Score=91, Evalue=5e-20,
Organism=Escherichia coli, GI1790717, Length=246, Percent_Identity=26.8292682926829, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI87082100, Length=252, Percent_Identity=28.1746031746032, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1787905, Length=246, Percent_Identity=29.6747967479675, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI87082160, Length=169, Percent_Identity=31.9526627218935, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI2367365, Length=234, Percent_Identity=23.5042735042735, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1789057, Length=199, Percent_Identity=25.6281407035176, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1789378, Length=259, Percent_Identity=26.2548262548263, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1786701, Length=183, Percent_Identity=29.5081967213115, Blast_Score=65, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI115534694, Length=249, Percent_Identity=31.7269076305221, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17562910, Length=272, Percent_Identity=32.3529411764706, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17560676, Length=250, Percent_Identity=30, Blast_Score=100, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI17560332, Length=263, Percent_Identity=31.5589353612167, Blast_Score=97, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI17531453, Length=266, Percent_Identity=28.9473684210526, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17559104, Length=270, Percent_Identity=28.1481481481481, Blast_Score=94, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI17562904, Length=270, Percent_Identity=29.2592592592593, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17555706, Length=247, Percent_Identity=30.7692307692308, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI193204405, Length=261, Percent_Identity=28.735632183908, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI25147288, Length=248, Percent_Identity=28.6290322580645, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17562906, Length=261, Percent_Identity=29.1187739463602, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17562908, Length=261, Percent_Identity=29.5019157088123, Blast_Score=90, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17538486, Length=268, Percent_Identity=28.7313432835821, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17538480, Length=264, Percent_Identity=29.5454545454545, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI71994604, Length=248, Percent_Identity=29.0322580645161, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17544670, Length=264, Percent_Identity=26.5151515151515, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17561402, Length=249, Percent_Identity=29.3172690763052, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17551412, Length=268, Percent_Identity=29.1044776119403, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71994600, Length=250, Percent_Identity=28, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17560220, Length=261, Percent_Identity=28.735632183908, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17565030, Length=275, Percent_Identity=28.3636363636364, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17560150, Length=267, Percent_Identity=27.3408239700375, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17562990, Length=265, Percent_Identity=26.7924528301887, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17563726, Length=265, Percent_Identity=28.6792452830189, Blast_Score=74, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI72000259, Length=268, Percent_Identity=27.6119402985075, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17536025, Length=252, Percent_Identity=26.1904761904762, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17538182, Length=251, Percent_Identity=26.2948207171315, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17561272, Length=197, Percent_Identity=27.9187817258883, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=185, Percent_Identity=27.027027027027, Blast_Score=70, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6323882, Length=249, Percent_Identity=28.1124497991968, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24639444, Length=250, Percent_Identity=30.4, Blast_Score=99, Evalue=2e-21,
Organism=Drosophila melanogaster, GI23397609, Length=252, Percent_Identity=30.1587301587302, Blast_Score=99, Evalue=2e-21,
Organism=Drosophila melanogaster, GI21357041, Length=251, Percent_Identity=29.4820717131474, Blast_Score=95, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24643142, Length=246, Percent_Identity=29.2682926829268, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI28571526, Length=254, Percent_Identity=29.9212598425197, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24644339, Length=248, Percent_Identity=28.6290322580645, Blast_Score=87, Evalue=7e-18,
Organism=Drosophila melanogaster, GI21355319, Length=247, Percent_Identity=27.1255060728745, Blast_Score=85, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24644337, Length=171, Percent_Identity=33.3333333333333, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24648693, Length=247, Percent_Identity=26.3157894736842, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21355889, Length=247, Percent_Identity=26.3157894736842, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21356301, Length=201, Percent_Identity=28.3582089552239, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 25240; Mature: 25108

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MSNRIVLITGATKGIGLATSLYLNNQGWQVIGIARSYIDNFPGELFLCDLANEEQTASTL
CCCCEEEEECCCCCCCEEEEEEECCCCCEEEEEEHHHHHCCCCCEEEEECCCCHHHHHHH
IQINEIHGCPDAIINNVGIAIPEPLGKISISALNDVYNLNVRSAVQVSQFFIEKMKLKEQ
EEEECCCCCHHHHHHCCCCCCCCCCCCEEHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
CKIVNIASRAIFGVKNLTSYSAAKSALVGCTKTWALELAKYGICVNAIAPGSVDTELFRK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCEEEEECCCCCCCHHHHHH
TRPIGSSEEKEVLDSIPMMRIGKPEEIAATIAFLLSNEASFIIGQVICVDGGGSL
HCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCC
>Mature Secondary Structure 
SNRIVLITGATKGIGLATSLYLNNQGWQVIGIARSYIDNFPGELFLCDLANEEQTASTL
CCCEEEEECCCCCCCEEEEEEECCCCCEEEEEEHHHHHCCCCCEEEEECCCCHHHHHHH
IQINEIHGCPDAIINNVGIAIPEPLGKISISALNDVYNLNVRSAVQVSQFFIEKMKLKEQ
EEEECCCCCHHHHHHCCCCCCCCCCCCEEHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
CKIVNIASRAIFGVKNLTSYSAAKSALVGCTKTWALELAKYGICVNAIAPGSVDTELFRK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCEEEEECCCCCCCHHHHHH
TRPIGSSEEKEVLDSIPMMRIGKPEEIAATIAFLLSNEASFIIGQVICVDGGGSL
HCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]