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The map label for this gene is shiA [H]

Identifier: 89256527

GI number: 89256527

Start: 1156139

End: 1156597

Strand: Reverse

Name: shiA [H]

Synonym: FTL_1206

Alternate gene names: 89256527

Gene position: 1156597-1156139 (Counterclockwise)

Preceding gene: 89256530

Following gene: 89256526

Centisome position: 61.0

GC content: 35.08

Gene sequence:

>459_bases
TTGCTTACAAATATTGGTGGAATGTTAGAATTTTATGACTTTGTCATATTTGGTATGTTTGCTATCGTGCTTGGTAAAAC
ATTTTTCCCTACCGAAGGCTCGCCAGCATTGCAAGCACTTTCTGCATTTACAGTTTTTGCTGTTGGATACTTTGCTAGAC
CATTTGGTGGAATTATTTTTGGTCATATAGGTGATAAATATGGACGTAAAAAATCTTTCTTACTGACAATACTACTTATG
GGTTTAGCTGCTTTTATGATTGCTATATTACCCTCTTATCAAAATGTTGGTATAATCGCACCACTATTATTTGTTATACT
AAGAATCATTCAAGGTGCTGCGATTGGTGGTGAAATTCCAAGTGCTGTAGTATTCGTCAAAGAATCACTACTAAAACATG
GTGGTTTAGCTTGTGGAATTATAGTTTGTTTTTTGCAGCTTTTGCAACTAGCTGCCTAA

Upstream 100 bases:

>100_bases
AAACTATTAGCTTTTTATAATTTATTAACTATTATAAAGACAATTTGAGTGTAATTATACTTAATTAAAGATGCTTTAAA
AAGATGATTTTAAAACGATT

Downstream 100 bases:

>100_bases
TTTTGCGATATTTTTTGCAGAGATCACTAAAATAGTAACTACATATTTCCTAAGTGATGACTATGCTTGGCATGTTGCAT
TTATGTTTGGAGGTATTGCT

Product: major facilitator transporter

Products: Proton [Cytoplasm]; shikimate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 152; Mature: 152

Protein sequence:

>152_residues
MLTNIGGMLEFYDFVIFGMFAIVLGKTFFPTEGSPALQALSAFTVFAVGYFARPFGGIIFGHIGDKYGRKKSFLLTILLM
GLAAFMIAILPSYQNVGIIAPLLFVILRIIQGAAIGGEIPSAVVFVKESLLKHGGLACGIIVCFLQLLQLAA

Sequences:

>Translated_152_residues
MLTNIGGMLEFYDFVIFGMFAIVLGKTFFPTEGSPALQALSAFTVFAVGYFARPFGGIIFGHIGDKYGRKKSFLLTILLM
GLAAFMIAILPSYQNVGIIAPLLFVILRIIQGAAIGGEIPSAVVFVKESLLKHGGLACGIIVCFLQLLQLAA
>Mature_152_residues
MLTNIGGMLEFYDFVIFGMFAIVLGKTFFPTEGSPALQALSAFTVFAVGYFARPFGGIIFGHIGDKYGRKKSFLLTILLM
GLAAFMIAILPSYQNVGIIAPLLFVILRIIQGAAIGGEIPSAVVFVKESLLKHGGLACGIIVCFLQLLQLAA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Escherichia coli, GI1788292, Length=129, Percent_Identity=46.5116279069767, Blast_Score=121, Evalue=2e-29,
Organism=Escherichia coli, GI1790550, Length=125, Percent_Identity=42.4, Blast_Score=114, Evalue=2e-27,
Organism=Escherichia coli, GI1788942, Length=123, Percent_Identity=38.2113821138211, Blast_Score=93, Evalue=9e-21,
Organism=Escherichia coli, GI1789941, Length=105, Percent_Identity=41.9047619047619, Blast_Score=88, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004736
- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR005828
- InterPro:   IPR005829 [H]

Pfam domain/function: PF00083 Sugar_tr [H]

EC number: NA

Molecular weight: Translated: 16252; Mature: 16252

Theoretical pI: Translated: 9.18; Mature: 9.18

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTNIGGMLEFYDFVIFGMFAIVLGKTFFPTEGSPALQALSAFTVFAVGYFARPFGGIIF
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHH
GHIGDKYGRKKSFLLTILLMGLAAFMIAILPSYQNVGIIAPLLFVILRIIQGAAIGGEIP
HHHCHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCH
SAVVFVKESLLKHGGLACGIIVCFLQLLQLAA
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLTNIGGMLEFYDFVIFGMFAIVLGKTFFPTEGSPALQALSAFTVFAVGYFARPFGGIIF
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHH
GHIGDKYGRKKSFLLTILLMGLAAFMIAILPSYQNVGIIAPLLFVILRIIQGAAIGGEIP
HHHCHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCH
SAVVFVKESLLKHGGLACGIIVCFLQLLQLAA
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; shikimate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + shikimate [Periplasm] = Proton [Cytoplasm] + shikimate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9524262; 9097040; 9278503 [H]