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The map label for this gene is aaeR [H]

Identifier: 89256514

GI number: 89256514

Start: 1142201

End: 1142989

Strand: Reverse

Name: aaeR [H]

Synonym: FTL_1193

Alternate gene names: 89256514

Gene position: 1142989-1142201 (Counterclockwise)

Preceding gene: 89256520

Following gene: 89256510

Centisome position: 60.28

GC content: 27.0

Gene sequence:

>789_bases
ATGCAAATCTTAGAAACAAAATATAGAAAATCACTATTTAATCGTAATACTAGGACTGTACACTTGACAGAATATGGAAA
ACTACTTTATGAAAAAGCTAGTTTAATACTAAACGAATTAGAAGCCACAGAAGAAAAAATTTTTGCCGAAGATATCCTAA
TAGATAGCGAATTAAAGATTTCTGTACCAAATTCATTTGGTATTAAATATCTTTGCAATATATTTTCTAAATTTGCTATT
GATTATCCAAAATATAAACTAAATATCAACTTATCAGATAGTTATATAAACATTATTGATGAAGATTTCGATTTAGTTAT
AAGAATTGGTGCTCTAGATGACTCAAATTTAATTACTAAAAAACTTATGCCGATGCCTAGTTTATTATGTGCAAGTGAAC
AATATTTAAAAAATTATGGCATACCTAAAACAATAAAAGATTTAGAGAATCATCTATTTATCCAATATAACAATCACAGC
TCATCAAATCGCATAATCCTAGAATCCGTCAATAAAACTGAGATAATAAATGTAAGACAAAGAATCGTAACTAATAGTGC
TGGAATGATGCTCCAGAGTTGTTTAGATGGCTTAGGCATAGCAAAGTTACCATTATTTGAAATTATCGATAAACTTCACG
ATAAAAAGCTAGTTCATCTATTACCTAATAACAGAAATCCTATAGAAAAAAATCTCTATTTAATAAGTTCAAGAGATAAA
TACAGATTAAAGAAAGTTAGGTTACTAAGCGCTTATATAGAGAAAAATTTGCCAAAGATTGAATTATAA

Upstream 100 bases:

>100_bases
TAAAGCACCTTTCTGTCATCAACATCCCCCGAACCAGAACTTATATGGATTAAATTATTAAGCAGCTATAGGCATATCTC
CACCAGTAGTATCAAAACAA

Downstream 100 bases:

>100_bases
AAGAATATAGATATTACTCAAAGAATTTTTTAGCGTAATCTTTAACATTGTCAAACCATGTTTTACTCTTTGGAGCATGC
TTACTTTGATAATCTTCACC

Product: LysR transcriptional regulator family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 262; Mature: 262

Protein sequence:

>262_residues
MQILETKYRKSLFNRNTRTVHLTEYGKLLYEKASLILNELEATEEKIFAEDILIDSELKISVPNSFGIKYLCNIFSKFAI
DYPKYKLNINLSDSYINIIDEDFDLVIRIGALDDSNLITKKLMPMPSLLCASEQYLKNYGIPKTIKDLENHLFIQYNNHS
SSNRIILESVNKTEIINVRQRIVTNSAGMMLQSCLDGLGIAKLPLFEIIDKLHDKKLVHLLPNNRNPIEKNLYLISSRDK
YRLKKVRLLSAYIEKNLPKIEL

Sequences:

>Translated_262_residues
MQILETKYRKSLFNRNTRTVHLTEYGKLLYEKASLILNELEATEEKIFAEDILIDSELKISVPNSFGIKYLCNIFSKFAI
DYPKYKLNINLSDSYINIIDEDFDLVIRIGALDDSNLITKKLMPMPSLLCASEQYLKNYGIPKTIKDLENHLFIQYNNHS
SSNRIILESVNKTEIINVRQRIVTNSAGMMLQSCLDGLGIAKLPLFEIIDKLHDKKLVHLLPNNRNPIEKNLYLISSRDK
YRLKKVRLLSAYIEKNLPKIEL
>Mature_262_residues
MQILETKYRKSLFNRNTRTVHLTEYGKLLYEKASLILNELEATEEKIFAEDILIDSELKISVPNSFGIKYLCNIFSKFAI
DYPKYKLNINLSDSYINIIDEDFDLVIRIGALDDSNLITKKLMPMPSLLCASEQYLKNYGIPKTIKDLENHLFIQYNNHS
SSNRIILESVNKTEIINVRQRIVTNSAGMMLQSCLDGLGIAKLPLFEIIDKLHDKKLVHLLPNNRNPIEKNLYLISSRDK
YRLKKVRLLSAYIEKNLPKIEL

Specific function: Activates transcription of the aaeXAB operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789639, Length=241, Percent_Identity=28.6307053941909, Blast_Score=124, Evalue=6e-30,
Organism=Escherichia coli, GI145693193, Length=246, Percent_Identity=29.2682926829268, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1786401, Length=254, Percent_Identity=27.9527559055118, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI1789440, Length=264, Percent_Identity=25.7575757575758, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI87081978, Length=271, Percent_Identity=27.3062730627306, Blast_Score=94, Evalue=7e-21,
Organism=Escherichia coli, GI1787128, Length=216, Percent_Identity=27.7777777777778, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1787589, Length=213, Percent_Identity=20.18779342723, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 30384; Mature: 30384

Theoretical pI: Translated: 9.13; Mature: 9.13

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQILETKYRKSLFNRNTRTVHLTEYGKLLYEKASLILNELEATEEKIFAEDILIDSELKI
CCCHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCEEE
SVPNSFGIKYLCNIFSKFAIDYPKYKLNINLSDSYINIIDEDFDLVIRIGALDDSNLITK
ECCCCCCHHHHHHHHHHHCCCCCCEEEEEEECCCEEEEECCCEEEEEEEECCCCCCHHHH
KLMPMPSLLCASEQYLKNYGIPKTIKDLENHLFIQYNNHSSSNRIILESVNKTEIINVRQ
HHCCCCHHHHHHHHHHHHCCCCHHHHHHHCCEEEEECCCCCCCEEEEEECCCHHHHHHHH
RIVTNSAGMMLQSCLDGLGIAKLPLFEIIDKLHDKKLVHLLPNNRNPIEKNLYLISSRDK
HHHHCHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCEEEEECCCCCCCCCCCEEEEECCCH
YRLKKVRLLSAYIEKNLPKIEL
HHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MQILETKYRKSLFNRNTRTVHLTEYGKLLYEKASLILNELEATEEKIFAEDILIDSELKI
CCCHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCEEE
SVPNSFGIKYLCNIFSKFAIDYPKYKLNINLSDSYINIIDEDFDLVIRIGALDDSNLITK
ECCCCCCHHHHHHHHHHHCCCCCCEEEEEEECCCEEEEECCCEEEEEEEECCCCCCHHHH
KLMPMPSLLCASEQYLKNYGIPKTIKDLENHLFIQYNNHSSSNRIILESVNKTEIINVRQ
HHCCCCHHHHHHHHHHHHCCCCHHHHHHHCCEEEEECCCCCCCEEEEEECCCHHHHHHHH
RIVTNSAGMMLQSCLDGLGIAKLPLFEIIDKLHDKKLVHLLPNNRNPIEKNLYLISSRDK
HHHHCHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCEEEEECCCCCCCCCCCEEEEECCCH
YRLKKVRLLSAYIEKNLPKIEL
HHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]