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The map label for this gene is mltA [H]

Identifier: 89256510

GI number: 89256510

Start: 1137112

End: 1138263

Strand: Reverse

Name: mltA [H]

Synonym: FTL_1189

Alternate gene names: 89256510

Gene position: 1138263-1137112 (Counterclockwise)

Preceding gene: 89256514

Following gene: 89256509

Centisome position: 60.04

GC content: 32.55

Gene sequence:

>1152_bases
ATGGATATTAAAAAAGTAAAAGAAACCTTAAAAAAAATAGTTATCATAGTTAGCTTAATACTTATAACTGGGTGTGCTAA
TATTACTGCGCAACAATATTTATCAAAAAAATATTCAAAAAATATAGATTATAAAAAATCAAGCTTCGAAGACTTAGCCA
ACTGGGATAGTGCTGATCAGCTTGAGTCTTTTAATACTTTTAAAAAATCTTGTGAAAAGATATTAGAAGAAAATAAACTA
GAATATTCAAACTGGATAAATATCTGCCATAAGGTTATAAATACAGATTTAAAAACTAAACAACAAGCTAAATTATTTTT
TGAGCAGAATTTCACTCCATACCAAATAATATATAAAGGAAAAGATACAGGTTTATTTACAGGCTATTATGAACCTTCGA
TGAAAGGTAGCTTAGTCAAAACTATGGAATATACCGTACCTATCTATCGCACACCTGATAACTTAGTAAAAAAACCTAAA
GATGATGATAGTTTTTCTTTCGGAATGTATCAAGATGGTAAATTTGTTCCTTATTACTCACGTGAAGAAATATCAAAAGG
TGATCTACTTCCAAAAAAAGATGTTTTAGTATGGGTAAAATCAAAAGTTGACCGAACATTTTTACAAATCCAAGGCTCTG
GTCGCATCGAAACTGACAGTGGTGACATTCTTATAGGTTACGATAGCCAAAATGGTCATGAATATAAGCCCATAGGTAAA
TATTTACTTGATCACGGTTATATGAGTGCTAAGCAAATGTCTATGCAAGCGATAAAAGCATGGCTAGATGAGAATAAAGA
TAAAATCGATGATGTACTAAACTATGACCCTTCTTTTGTGTTTTTTAGATACATTGATCGCAAAAATGCTGTTGGTGCAC
AAGATGTTGAACTAACACCTGGATATTCTCTTGCTGTTGATAACAAATACTATCTGTATGGCGTACCCTTATGGTTAGAG
ACAGATTATTTTGCTGATAATCATGATGATACAAAACCTCTTGATAGGCTAATGATAGCTCAAGACACAGGTGGTGCTAT
AAAGGGCGCTATCAGAAGTGATGTATTTTGGGGACATGGTAAGCAAGCAGAATTTAACGCCGGCCATATGAATAACCGCG
GCAAACTATGGATACTTTTACCAAATGACTGA

Upstream 100 bases:

>100_bases
ACAACCTTTTATTTTAGTTCTGTTAATACTACAATTTGTTAGATGTCTTATAGATAGTGATTAATTCTGTATTTTCAAGA
AATTATTGGTATTTTTTTAT

Downstream 100 bases:

>100_bases
TACAAAACATTTTGATACTATTATAATTGGTGCTGGAATTTCAGGTATATCTTTAGCACAACGATTAACTGCTGCATCTG
TAAAAAATTGTGTCTTTGAG

Product: membrane-bound lytic murein transglycosylase A (MLT) family protein

Products: Muramic Acid Residue [C]

Alternate protein names: Mlt38; Murein hydrolase A [H]

Number of amino acids: Translated: 383; Mature: 383

Protein sequence:

>383_residues
MDIKKVKETLKKIVIIVSLILITGCANITAQQYLSKKYSKNIDYKKSSFEDLANWDSADQLESFNTFKKSCEKILEENKL
EYSNWINICHKVINTDLKTKQQAKLFFEQNFTPYQIIYKGKDTGLFTGYYEPSMKGSLVKTMEYTVPIYRTPDNLVKKPK
DDDSFSFGMYQDGKFVPYYSREEISKGDLLPKKDVLVWVKSKVDRTFLQIQGSGRIETDSGDILIGYDSQNGHEYKPIGK
YLLDHGYMSAKQMSMQAIKAWLDENKDKIDDVLNYDPSFVFFRYIDRKNAVGAQDVELTPGYSLAVDNKYYLYGVPLWLE
TDYFADNHDDTKPLDRLMIAQDTGGAIKGAIRSDVFWGHGKQAEFNAGHMNNRGKLWILLPND

Sequences:

>Translated_383_residues
MDIKKVKETLKKIVIIVSLILITGCANITAQQYLSKKYSKNIDYKKSSFEDLANWDSADQLESFNTFKKSCEKILEENKL
EYSNWINICHKVINTDLKTKQQAKLFFEQNFTPYQIIYKGKDTGLFTGYYEPSMKGSLVKTMEYTVPIYRTPDNLVKKPK
DDDSFSFGMYQDGKFVPYYSREEISKGDLLPKKDVLVWVKSKVDRTFLQIQGSGRIETDSGDILIGYDSQNGHEYKPIGK
YLLDHGYMSAKQMSMQAIKAWLDENKDKIDDVLNYDPSFVFFRYIDRKNAVGAQDVELTPGYSLAVDNKYYLYGVPLWLE
TDYFADNHDDTKPLDRLMIAQDTGGAIKGAIRSDVFWGHGKQAEFNAGHMNNRGKLWILLPND
>Mature_383_residues
MDIKKVKETLKKIVIIVSLILITGCANITAQQYLSKKYSKNIDYKKSSFEDLANWDSADQLESFNTFKKSCEKILEENKL
EYSNWINICHKVINTDLKTKQQAKLFFEQNFTPYQIIYKGKDTGLFTGYYEPSMKGSLVKTMEYTVPIYRTPDNLVKKPK
DDDSFSFGMYQDGKFVPYYSREEISKGDLLPKKDVLVWVKSKVDRTFLQIQGSGRIETDSGDILIGYDSQNGHEYKPIGK
YLLDHGYMSAKQMSMQAIKAWLDENKDKIDDVLNYDPSFVFFRYIDRKNAVGAQDVELTPGYSLAVDNKYYLYGVPLWLE
TDYFADNHDDTKPLDRLMIAQDTGGAIKGAIRSDVFWGHGKQAEFNAGHMNNRGKLWILLPND

Specific function: Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division. Degrades murein glycan strands and insoluble, high-molecular weight murein sacculi [H]

COG id: COG2821

COG function: function code M; Membrane-bound lytic murein transglycosylase

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789179, Length=380, Percent_Identity=27.6315789473684, Blast_Score=125, Evalue=4e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010611
- InterPro:   IPR014733
- InterPro:   IPR005300 [H]

Pfam domain/function: PF06725 3D; PF03562 MltA [H]

EC number: 3.2.1.- [C]

Molecular weight: Translated: 44135; Mature: 44135

Theoretical pI: Translated: 7.12; Mature: 7.12

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIKKVKETLKKIVIIVSLILITGCANITAQQYLSKKYSKNIDYKKSSFEDLANWDSADQ
CCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHH
LESFNTFKKSCEKILEENKLEYSNWINICHKVINTDLKTKQQAKLFFEQNFTPYQIIYKG
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCEEEEEEC
KDTGLFTGYYEPSMKGSLVKTMEYTVPIYRTPDNLVKKPKDDDSFSFGMYQDGKFVPYYS
CCCCEEEEEECCCCCCCEEEEEEEEEEEEECCHHHHCCCCCCCCEEECEECCCCCCCCCC
REEISKGDLLPKKDVLVWVKSKVDRTFLQIQGSGRIETDSGDILIGYDSQNGHEYKPIGK
HHCCCCCCCCCCCCEEEEEHHHCCEEEEEEECCCEEECCCCCEEEEECCCCCCCCCHHHH
YLLDHGYMSAKQMSMQAIKAWLDENKDKIDDVLNYDPSFVFFRYIDRKNAVGAQDVELTP
HHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCEEEEEEECCCCCCCCCCEEECC
GYSLAVDNKYYLYGVPLWLETDYFADNHDDTKPLDRLMIAQDTGGAIKGAIRSDVFWGHG
CEEEEECCEEEEEEEEEEEEECCCCCCCCCCCHHHHEEEEECCCCHHHHHHHHCEEECCC
KQAEFNAGHMNNRGKLWILLPND
CCCCCCCCCCCCCCEEEEEECCC
>Mature Secondary Structure
MDIKKVKETLKKIVIIVSLILITGCANITAQQYLSKKYSKNIDYKKSSFEDLANWDSADQ
CCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHH
LESFNTFKKSCEKILEENKLEYSNWINICHKVINTDLKTKQQAKLFFEQNFTPYQIIYKG
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCEEEEEEC
KDTGLFTGYYEPSMKGSLVKTMEYTVPIYRTPDNLVKKPKDDDSFSFGMYQDGKFVPYYS
CCCCEEEEEECCCCCCCEEEEEEEEEEEEECCHHHHCCCCCCCCEEECEECCCCCCCCCC
REEISKGDLLPKKDVLVWVKSKVDRTFLQIQGSGRIETDSGDILIGYDSQNGHEYKPIGK
HHCCCCCCCCCCCCEEEEEHHHCCEEEEEEECCCEEECCCCCEEEEECCCCCCCCCHHHH
YLLDHGYMSAKQMSMQAIKAWLDENKDKIDDVLNYDPSFVFFRYIDRKNAVGAQDVELTP
HHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCEEEEEEECCCCCCCCCCEEECC
GYSLAVDNKYYLYGVPLWLETDYFADNHDDTKPLDRLMIAQDTGGAIKGAIRSDVFWGHG
CEEEEECCEEEEEEEEEEEEECCCCCCCCCCCHHHHEEEEECCCCHHHHHHHHCEEECCC
KQAEFNAGHMNNRGKLWILLPND
CCCCCCCCCCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Muramic Acid Residue (N-Acetylmuramic Acid And N-Acetylglucosamine Residues) [C]

Specific reaction: Cleavage Of The Beta-1,4-Glycosidic [C]

General reaction: Cleavage Bond [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]