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The map label for this gene is ttdR [H]

Identifier: 89256497

GI number: 89256497

Start: 1127680

End: 1128132

Strand: Direct

Name: ttdR [H]

Synonym: FTL_1176

Alternate gene names: 89256497

Gene position: 1127680-1128132 (Clockwise)

Preceding gene: 89256482

Following gene: 89256500

Centisome position: 59.48

GC content: 28.92

Gene sequence:

>453_bases
ATGAATTTTGATGATATTTTCCTTTTTGTTAAGCTTGTTAATATTGGAACATTTACCGAATTAGCAAAACAGTTAAATGT
TTCTCAGAGCACAGTTTCACGGAGGATTCAAAGTTTAGAAGAATCTATTAATACTAAGTTGATAAAGAGAAATTCAAGAG
GTGTTATCGAAGTAACCACAGAAGGACAATCTCTATATAACAATTTTAGTTATATTGAAGAACAAGCTGTTGTGACATTT
CAAAAGTGGATTAATAATTCAAAACAAATCAAAGGTATTTTAAGAGTAGGAGTACCAAAGTTGTTTTTTGATAACCTTGT
TGCTCCAAAGCTTGATACATTTTATACACGCTATCCTAATGTACAATTAGTATTTAGTTATACTGCTGGAATTGTTGATT
TAGTAAAAGATAATATAGACATAGCGATTACAAAAAAAACCAACAACGAATAA

Upstream 100 bases:

>100_bases
AAAATTAGTCAATTAACTTACGCTAATAGTATATTTGTAGTAGTATTAATTTGTCTGTAGCAAAAAATGCATAACTATTA
TGCGTAAATAGAGGACCACT

Downstream 100 bases:

>100_bases
TTGCACTATAAAAACACTTCTTAAATCCAAGAATAAGCTTTATGCGTCTAAAAAATATATTCAAGAAAAAGGGGTTCCTG
AGACAATAAAGGAATTAGAA

Product: LysR transcriptional regulator family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 150; Mature: 150

Protein sequence:

>150_residues
MNFDDIFLFVKLVNIGTFTELAKQLNVSQSTVSRRIQSLEESINTKLIKRNSRGVIEVTTEGQSLYNNFSYIEEQAVVTF
QKWINNSKQIKGILRVGVPKLFFDNLVAPKLDTFYTRYPNVQLVFSYTAGIVDLVKDNIDIAITKKTNNE

Sequences:

>Translated_150_residues
MNFDDIFLFVKLVNIGTFTELAKQLNVSQSTVSRRIQSLEESINTKLIKRNSRGVIEVTTEGQSLYNNFSYIEEQAVVTF
QKWINNSKQIKGILRVGVPKLFFDNLVAPKLDTFYTRYPNVQLVFSYTAGIVDLVKDNIDIAITKKTNNE
>Mature_150_residues
MNFDDIFLFVKLVNIGTFTELAKQLNVSQSTVSRRIQSLEESINTKLIKRNSRGVIEVTTEGQSLYNNFSYIEEQAVVTF
QKWINNSKQIKGILRVGVPKLFFDNLVAPKLDTFYTRYPNVQLVFSYTAGIVDLVKDNIDIAITKKTNNE

Specific function: Positive regulator required for L-tartrate-dependent anaerobic growth on glycerol. Induces expression of the ttdA-ttdB- ygjE operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789440, Length=150, Percent_Identity=32, Blast_Score=77, Evalue=5e-16,
Organism=Escherichia coli, GI1786401, Length=144, Percent_Identity=25.6944444444444, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI145693193, Length=143, Percent_Identity=29.3706293706294, Blast_Score=68, Evalue=3e-13,
Organism=Escherichia coli, GI1788297, Length=147, Percent_Identity=27.2108843537415, Blast_Score=64, Evalue=5e-12,
Organism=Escherichia coli, GI1789173, Length=127, Percent_Identity=30.7086614173228, Blast_Score=62, Evalue=1e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 17175; Mature: 17175

Theoretical pI: Translated: 9.64; Mature: 9.64

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFDDIFLFVKLVNIGTFTELAKQLNVSQSTVSRRIQSLEESINTKLIKRNSRGVIEVTT
CCHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEE
EGQSLYNNFSYIEEQAVVTFQKWINNSKQIKGILRVGVPKLFFDNLVAPKLDTFYTRYPN
CCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHCCCCCHHHHHHCCCC
VQLVFSYTAGIVDLVKDNIDIAITKKTNNE
EEEEEEHHHHHHHHHHCCCCEEEEECCCCC
>Mature Secondary Structure
MNFDDIFLFVKLVNIGTFTELAKQLNVSQSTVSRRIQSLEESINTKLIKRNSRGVIEVTT
CCHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEE
EGQSLYNNFSYIEEQAVVTFQKWINNSKQIKGILRVGVPKLFFDNLVAPKLDTFYTRYPN
CCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHCCCCCHHHHHHCCCC
VQLVFSYTAGIVDLVKDNIDIAITKKTNNE
EEEEEEHHHHHHHHHHCCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]