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The map label for this gene is treA [H]

Identifier: 89256474

GI number: 89256474

Start: 1093090

End: 1093644

Strand: Reverse

Name: treA [H]

Synonym: FTL_1150

Alternate gene names: 89256474

Gene position: 1093644-1093090 (Counterclockwise)

Preceding gene: 89256475

Following gene: 89256468

Centisome position: 57.68

GC content: 29.37

Gene sequence:

>555_bases
ATGGTTCACAGAATTTTTACAACAAAAAAAAGCTACCAAGTATCTAGAATTAGCAAAAAAAGAAAACAACTTATTCAGGA
TAAATTTTGGAATAACCAAAAAGAATTTTTTTATGATCTAAATCATGTTAAGAATGAACTTACAGATATTACAAGTCTAG
CTGGAATAGCTCCTTTATTCTTAAACATAGCAACAGATCAGCAAGCACTGAAAGTTGCTAAAATTATAGAAAAAGATTTT
TTAACTGAATATGGCCTTATTACAACTCTTACAAATACAACACAACAATGGGATTCTCCAAATGGTTGGGCTCTATTACA
CTTTGAGGCAGTAATAGGTTTAAATAATTATGGTTTTGATAAACTTGCAAAAACTATTGCAACAAGGTTTATAAATACAG
TTAATGCAAAATTTAAACAAACTGGAAAAATTCGTGAAAAATACGATGTAATAATCCCCGAGCAAAAAGCAGGAGGAGGA
GAGTATATAGTCCAAGATGGTTTTGGCTGGACTAATGGAGTAGTTAAAAGTTTTATTAAAATGTATAATTTATGA

Upstream 100 bases:

>100_bases
GGTTTGCCAAAGCAGATGATTTTAATACCATCCAAACAACTGATATTTTACCTGTTGATTTAAATAGTTATTTATATGGA
TTAGAACATTTACTAGGTAA

Downstream 100 bases:

>100_bases
GAAATAATTCTTAACAAAGTTGTCAAAAAAAGTTTTTATCTATTATGAATAACTAGATTCTATACATGATTTATCAGTTA
ACGACTATAAGAGTTTAAAA

Product: Alpha,alpha-trehalase.

Products: NA

Alternate protein names: Alpha,alpha-trehalase; Alpha,alpha-trehalose glucohydrolase [H]

Number of amino acids: Translated: 184; Mature: 184

Protein sequence:

>184_residues
MVHRIFTTKKSYQVSRISKKRKQLIQDKFWNNQKEFFYDLNHVKNELTDITSLAGIAPLFLNIATDQQALKVAKIIEKDF
LTEYGLITTLTNTTQQWDSPNGWALLHFEAVIGLNNYGFDKLAKTIATRFINTVNAKFKQTGKIREKYDVIIPEQKAGGG
EYIVQDGFGWTNGVVKSFIKMYNL

Sequences:

>Translated_184_residues
MVHRIFTTKKSYQVSRISKKRKQLIQDKFWNNQKEFFYDLNHVKNELTDITSLAGIAPLFLNIATDQQALKVAKIIEKDF
LTEYGLITTLTNTTQQWDSPNGWALLHFEAVIGLNNYGFDKLAKTIATRFINTVNAKFKQTGKIREKYDVIIPEQKAGGG
EYIVQDGFGWTNGVVKSFIKMYNL
>Mature_184_residues
MVHRIFTTKKSYQVSRISKKRKQLIQDKFWNNQKEFFYDLNHVKNELTDITSLAGIAPLFLNIATDQQALKVAKIIEKDF
LTEYGLITTLTNTTQQWDSPNGWALLHFEAVIGLNNYGFDKLAKTIATRFINTVNAKFKQTGKIREKYDVIIPEQKAGGG
EYIVQDGFGWTNGVVKSFIKMYNL

Specific function: Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system [H]

COG id: COG1626

COG function: function code G; Neutral trehalase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 37 family [H]

Homologues:

Organism=Homo sapiens, GI116284412, Length=177, Percent_Identity=33.8983050847458, Blast_Score=73, Evalue=2e-13,
Organism=Escherichia coli, GI1789936, Length=167, Percent_Identity=35.9281437125749, Blast_Score=121, Evalue=3e-29,
Organism=Escherichia coli, GI1787447, Length=176, Percent_Identity=39.7727272727273, Blast_Score=114, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17542196, Length=170, Percent_Identity=30.5882352941176, Blast_Score=81, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI71987755, Length=184, Percent_Identity=35.3260869565217, Blast_Score=75, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17565078, Length=174, Percent_Identity=29.3103448275862, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI25148109, Length=104, Percent_Identity=40.3846153846154, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI25141398, Length=172, Percent_Identity=29.0697674418605, Blast_Score=64, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24656680, Length=177, Percent_Identity=32.2033898305085, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24656675, Length=177, Percent_Identity=32.2033898305085, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24656685, Length=177, Percent_Identity=32.2033898305085, Blast_Score=78, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24656661, Length=177, Percent_Identity=32.2033898305085, Blast_Score=78, Evalue=3e-15,
Organism=Drosophila melanogaster, GI17933716, Length=177, Percent_Identity=32.2033898305085, Blast_Score=78, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24656670, Length=177, Percent_Identity=32.2033898305085, Blast_Score=78, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008928
- InterPro:   IPR001661
- InterPro:   IPR018232 [H]

Pfam domain/function: PF01204 Trehalase [H]

EC number: =3.2.1.28 [H]

Molecular weight: Translated: 21162; Mature: 21162

Theoretical pI: Translated: 10.12; Mature: 10.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVHRIFTTKKSYQVSRISKKRKQLIQDKFWNNQKEFFYDLNHVKNELTDITSLAGIAPLF
CCCCEECCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LNIATDQQALKVAKIIEKDFLTEYGLITTLTNTTQQWDSPNGWALLHFEAVIGLNNYGFD
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCEEEEEEEEEECCCCCCHH
KLAKTIATRFINTVNAKFKQTGKIREKYDVIIPEQKAGGGEYIVQDGFGWTNGVVKSFIK
HHHHHHHHHHHHHHHHHHHHCCCHHHHHCEECCCCCCCCCCEEEECCCCCHHHHHHHHHH
MYNL
HHCC
>Mature Secondary Structure
MVHRIFTTKKSYQVSRISKKRKQLIQDKFWNNQKEFFYDLNHVKNELTDITSLAGIAPLF
CCCCEECCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LNIATDQQALKVAKIIEKDFLTEYGLITTLTNTTQQWDSPNGWALLHFEAVIGLNNYGFD
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCEEEEEEEEEECCCCCCHH
KLAKTIATRFINTVNAKFKQTGKIREKYDVIIPEQKAGGGEYIVQDGFGWTNGVVKSFIK
HHHHHHHHHHHHHHHHHHHHCCCHHHHHCEECCCCCCCCCCEEEECCCCCHHHHHHHHHH
MYNL
HHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]