Click here to switch to the map view.

The map label for this gene is gap [H]

Identifier: 89256470

GI number: 89256470

Start: 1088189

End: 1089190

Strand: Direct

Name: gap [H]

Synonym: FTL_1146

Alternate gene names: 89256470

Gene position: 1088189-1089190 (Clockwise)

Preceding gene: 89256469

Following gene: 89256471

Centisome position: 57.39

GC content: 38.02

Gene sequence:

>1002_bases
ATGAGAGTTGCAATTAATGGTTTCGGTAGAATTGGTCGTTTAGCATTTCGTCAAATGTTTGGTAAAGATAACATTGAGAT
TGTCGCGATTAATGATTTAACAAATCCTGAGATGTTAGCACACTTATTGAAATATGATTCTGCTCAAGGTAGATTCTCAA
AAGCAGCTGTAACAGTAGCAAAAGAAAGTTCTATAGTTGTCGATGGTAAAGAGATTAAAATATATGCTGAAAAAGATGCA
GCTAATCTACCTTGGGGCGAGTTAAATGTCGATGTTGTACTAGAGTGCACTGGTTTTTATGTATCAAAAGCAAAGTCACA
AGCTCATATTGATGCAGGTGCTAAAAAAGTAGTTATTTCAGCGCCAGCTGGTAATGACCTACCAACAGTTGTCTTTAGTG
TTAATCATGACATCCTCAGCGCAGATGATAAAATCATATCAGCGGCTTCTTGTACAACTAATTGTCTAGCTCCTATGGCT
AAAGCTCTTCATGATCTAGCAAACATTGAAAGTGGTTTTATGACCACTATTCATGCATATACAGGTGACCAAAATACTTT
AGATGCTCCTCATGCGAAAAATGACTTCCGTCGTGCAAGAGCTGCTGCTGTAAATATTGTACCTAACTCAACTGGTGCCG
CTAAAGCTATTGGTTTAGTGATTCCTGAACTTGCTGGTAAGTTAGATGGGGCTGCTCAGCGTGTCCCTGTTGCTACTGGT
TCTTTAACTGAGCTTGTTGCTGTCGTATCTAAGAAGGTAACAGCTGAAGATGTTAATGCTGCGATGAAAGCTGCTGCAAA
TAAATCTTTTGGTTACACAGAAGAAGAGCTAGTATCTAGTGATATCATCGGGATTTCTGAAGGATCGTTATTCGATGCAA
CTCAAACTAAAGTTACTTCACTAGGTGATAAATCTCTAGTTAAAGTAGTATCTTGGTATGACAATGAAATGTCTTATACA
AATCAAATGGTTAGAGTAGTAGAGTACTTCGGAGCTCTATAA

Upstream 100 bases:

>100_bases
TTATTTAAACATTTTGGATTTACTGTAGAAAATATTAGCAATATTGTTGCTAAATATGTTTAATAAACTTTCGCAAGATA
ATATCTTAAGGAGATTAAAA

Downstream 100 bases:

>100_bases
ACATTATAGGTGATATAAATGAGTTTTCTAACATTGAAAGATGTTGATTTAAAAGATAAAAAAGTCTTGGTTCGTGTTGA
CTTCAACGTACCTGTTAAAG

Product: glyceraldehyde-3-phosphate dehydrogenase

Products: NA

Alternate protein names: GAPDH [H]

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MRVAINGFGRIGRLAFRQMFGKDNIEIVAINDLTNPEMLAHLLKYDSAQGRFSKAAVTVAKESSIVVDGKEIKIYAEKDA
ANLPWGELNVDVVLECTGFYVSKAKSQAHIDAGAKKVVISAPAGNDLPTVVFSVNHDILSADDKIISAASCTTNCLAPMA
KALHDLANIESGFMTTIHAYTGDQNTLDAPHAKNDFRRARAAAVNIVPNSTGAAKAIGLVIPELAGKLDGAAQRVPVATG
SLTELVAVVSKKVTAEDVNAAMKAAANKSFGYTEEELVSSDIIGISEGSLFDATQTKVTSLGDKSLVKVVSWYDNEMSYT
NQMVRVVEYFGAL

Sequences:

>Translated_333_residues
MRVAINGFGRIGRLAFRQMFGKDNIEIVAINDLTNPEMLAHLLKYDSAQGRFSKAAVTVAKESSIVVDGKEIKIYAEKDA
ANLPWGELNVDVVLECTGFYVSKAKSQAHIDAGAKKVVISAPAGNDLPTVVFSVNHDILSADDKIISAASCTTNCLAPMA
KALHDLANIESGFMTTIHAYTGDQNTLDAPHAKNDFRRARAAAVNIVPNSTGAAKAIGLVIPELAGKLDGAAQRVPVATG
SLTELVAVVSKKVTAEDVNAAMKAAANKSFGYTEEELVSSDIIGISEGSLFDATQTKVTSLGDKSLVKVVSWYDNEMSYT
NQMVRVVEYFGAL
>Mature_333_residues
MRVAINGFGRIGRLAFRQMFGKDNIEIVAINDLTNPEMLAHLLKYDSAQGRFSKAAVTVAKESSIVVDGKEIKIYAEKDA
ANLPWGELNVDVVLECTGFYVSKAKSQAHIDAGAKKVVISAPAGNDLPTVVFSVNHDILSADDKIISAASCTTNCLAPMA
KALHDLANIESGFMTTIHAYTGDQNTLDAPHAKNDFRRARAAAVNIVPNSTGAAKAIGLVIPELAGKLDGAAQRVPVATG
SLTELVAVVSKKVTAEDVNAAMKAAANKSFGYTEEELVSSDIIGISEGSLFDATQTKVTSLGDKSLVKVVSWYDNEMSYT
NQMVRVVEYFGAL

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=335, Percent_Identity=42.6865671641791, Blast_Score=263, Evalue=1e-70,
Organism=Homo sapiens, GI7657116, Length=336, Percent_Identity=42.8571428571429, Blast_Score=256, Evalue=2e-68,
Organism=Escherichia coli, GI1788079, Length=334, Percent_Identity=46.7065868263473, Blast_Score=293, Evalue=2e-80,
Organism=Escherichia coli, GI1789295, Length=333, Percent_Identity=43.2432432432432, Blast_Score=249, Evalue=2e-67,
Organism=Caenorhabditis elegans, GI17568413, Length=339, Percent_Identity=45.1327433628319, Blast_Score=270, Evalue=8e-73,
Organism=Caenorhabditis elegans, GI32566163, Length=339, Percent_Identity=45.1327433628319, Blast_Score=270, Evalue=8e-73,
Organism=Caenorhabditis elegans, GI17534677, Length=337, Percent_Identity=45.4005934718101, Blast_Score=269, Evalue=1e-72,
Organism=Caenorhabditis elegans, GI17534679, Length=337, Percent_Identity=45.4005934718101, Blast_Score=268, Evalue=3e-72,
Organism=Saccharomyces cerevisiae, GI6321631, Length=335, Percent_Identity=48.0597014925373, Blast_Score=301, Evalue=1e-82,
Organism=Saccharomyces cerevisiae, GI6322409, Length=334, Percent_Identity=47.0059880239521, Blast_Score=298, Evalue=8e-82,
Organism=Saccharomyces cerevisiae, GI6322468, Length=334, Percent_Identity=46.7065868263473, Blast_Score=295, Evalue=1e-80,
Organism=Drosophila melanogaster, GI19922412, Length=332, Percent_Identity=44.578313253012, Blast_Score=271, Evalue=5e-73,
Organism=Drosophila melanogaster, GI17933600, Length=334, Percent_Identity=43.7125748502994, Blast_Score=265, Evalue=4e-71,
Organism=Drosophila melanogaster, GI18110149, Length=334, Percent_Identity=43.7125748502994, Blast_Score=265, Evalue=4e-71,
Organism=Drosophila melanogaster, GI85725000, Length=334, Percent_Identity=43.7125748502994, Blast_Score=263, Evalue=2e-70,
Organism=Drosophila melanogaster, GI22023983, Length=334, Percent_Identity=43.7125748502994, Blast_Score=263, Evalue=2e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 35414; Mature: 35414

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVAINGFGRIGRLAFRQMFGKDNIEIVAINDLTNPEMLAHLLKYDSAQGRFSKAAVTVA
CEEEECCCCHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHCCCCCCCCHHHEEEEE
KESSIVVDGKEIKIYAEKDAANLPWGELNVDVVLECTGFYVSKAKSQAHIDAGAKKVVIS
ECCEEEEECCEEEEEECCCCCCCCCCCCCEEEEEEECCHHHHHCCCHHHHCCCCCEEEEE
APAGNDLPTVVFSVNHDILSADDKIISAASCTTNCLAPMAKALHDLANIESGFMTTIHAY
CCCCCCCCEEEEEECCCEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEE
TGDQNTLDAPHAKNDFRRARAAAVNIVPNSTGAAKAIGLVIPELAGKLDGAAQRVPVATG
CCCCCCCCCCCCHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHCCCCCCHHCCCCCCC
SLTELVAVVSKKVTAEDVNAAMKAAANKSFGYTEEELVSSDIIGISEGSLFDATQTKVTS
HHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCHHHHHHHCCEECCCCCEECCHHHHHHH
LGDKSLVKVVSWYDNEMSYTNQMVRVVEYFGAL
CCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRVAINGFGRIGRLAFRQMFGKDNIEIVAINDLTNPEMLAHLLKYDSAQGRFSKAAVTVA
CEEEECCCCHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHCCCCCCCCHHHEEEEE
KESSIVVDGKEIKIYAEKDAANLPWGELNVDVVLECTGFYVSKAKSQAHIDAGAKKVVIS
ECCEEEEECCEEEEEECCCCCCCCCCCCCEEEEEEECCHHHHHCCCHHHHCCCCCEEEEE
APAGNDLPTVVFSVNHDILSADDKIISAASCTTNCLAPMAKALHDLANIESGFMTTIHAY
CCCCCCCCEEEEEECCCEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEE
TGDQNTLDAPHAKNDFRRARAAAVNIVPNSTGAAKAIGLVIPELAGKLDGAAQRVPVATG
CCCCCCCCCCCCHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHCCCCCCHHCCCCCCC
SLTELVAVVSKKVTAEDVNAAMKAAANKSFGYTEEELVSSDIIGISEGSLFDATQTKVTS
HHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCHHHHHHHCCEECCCCCEECCHHHHHHH
LGDKSLVKVVSWYDNEMSYTNQMVRVVEYFGAL
CCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10463150; 11466286 [H]