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The map label for this gene is hipA [C]

Identifier: 89256450

GI number: 89256450

Start: 1069990

End: 1071246

Strand: Reverse

Name: hipA [C]

Synonym: FTL_1125

Alternate gene names: 89256450

Gene position: 1071246-1069990 (Counterclockwise)

Preceding gene: 89256451

Following gene: 89256443

Centisome position: 56.5

GC content: 30.63

Gene sequence:

>1257_bases
ATGTCTAACCAACTAAATGTCCATTTGAAAGACATACATATTGGATATCTAAAAAAACAAGGTTCAAAACTAAGCTTTAA
CTATTCAAAAGAATATTTAGATTCAGAGAATGCTCAGCCTATATCCATAAGTATTCCTTTATCTGAAAACGAGTATAAGC
ATGATGTAGTTCACCCATTTTTTTCTGGATTACTGCCTGATGAGCCGGCTAGATCAAGATTAGCAAAATATTTACATATC
TCTAATAAGAATACTTTTGAGCTTCTTAAAGCTATTGGTGGCGAGTGTGCTGGTGCTATATCAGTATATGATGGACAACC
ATCAGTTGATAATAACACAGAGAATGATTATCGTATTTTAAAAGATGACGAAGCTTATAGGCTTTTTAATGAACTTAAAG
TTCGTCCTTTGCTTATTGGTGAAGATGATTTTAGAATCTCTGGCGCCGGTGCTCAAGATAAAATGATAATAGCTTTTGTA
GATAATCAAGTTGCTATTCCTCTACACAATACTCCATCTACTCATATTATTAAACCAGCAATTGATGAGCTAGATGATAC
TGTCTTTAATGAGTTTTTTTGTATGAGATTGGCTAGTGCTATGGGATTAAACACTTCAAAGCCAGATATTATTTGGCTGG
AAAATAATCCTTTTTATGTAGTAGAGAGATATGATAGAGAATTCACACCTGACGGAAAAATTATTAGACTTCATCAAGAA
GATTTCTGTCAAGCTTTGGATATTGAACCAGATGTTAAATACCAAAATGAAGGTGGGCCTTCATTTATTGACTGTTTTGA
ATTGATAAATACTCTTATTAAATATGGTAAGATGTCTACGATTAATAAAGTAGCTCTGTTTGATGCTAGTATTTTCAATT
TCTTAATCGGAAATGGCGATGCTCATGCAAAAAACTTTTCACTATTATATAGAAACTTAAAAATAGAGCTTGCTCCTTTA
TATGATATTTTATCAACTATAATTTATAGTCAACCATATCAAAAGGCTAAAATGTCAATGAATGTTGATAGTAAATGTAA
GTTTTGCCAAATACAAAAAAGACACTTTGTGGAATTAGGTAAATCTATTGGCTTCAAAGAGGGCTATTGCATAAAAAGAA
TAGAAAGCATAGCTAGTAAAATATTGCCAATAGCAAAACAGCTACAACAAGAATTAAACATTAACAATAAATATAAATCT
GAAATTTATCAAAATATTATAGATCTTATAGAACAAACATCTAAACAACTAAGTTAA

Upstream 100 bases:

>100_bases
AAAATGGTAAAAATACGGCTCATATCGGAAAGGTTATACAACTTGCTAGTAGTTTAGGCTTGGTAATTTCTGTTGGCTGT
GATTGGATGGAGGACTGATA

Downstream 100 bases:

>100_bases
TTCAATACAGTGGTATACAAAGAATTACATCTAGCTAAAAGCATTGTAAATAAAGGGTTTTATTTTATTGCTCGAATCCA
GTTGCGTACCAGTAATTATT

Product: transcription regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 418; Mature: 417

Protein sequence:

>418_residues
MSNQLNVHLKDIHIGYLKKQGSKLSFNYSKEYLDSENAQPISISIPLSENEYKHDVVHPFFSGLLPDEPARSRLAKYLHI
SNKNTFELLKAIGGECAGAISVYDGQPSVDNNTENDYRILKDDEAYRLFNELKVRPLLIGEDDFRISGAGAQDKMIIAFV
DNQVAIPLHNTPSTHIIKPAIDELDDTVFNEFFCMRLASAMGLNTSKPDIIWLENNPFYVVERYDREFTPDGKIIRLHQE
DFCQALDIEPDVKYQNEGGPSFIDCFELINTLIKYGKMSTINKVALFDASIFNFLIGNGDAHAKNFSLLYRNLKIELAPL
YDILSTIIYSQPYQKAKMSMNVDSKCKFCQIQKRHFVELGKSIGFKEGYCIKRIESIASKILPIAKQLQQELNINNKYKS
EIYQNIIDLIEQTSKQLS

Sequences:

>Translated_418_residues
MSNQLNVHLKDIHIGYLKKQGSKLSFNYSKEYLDSENAQPISISIPLSENEYKHDVVHPFFSGLLPDEPARSRLAKYLHI
SNKNTFELLKAIGGECAGAISVYDGQPSVDNNTENDYRILKDDEAYRLFNELKVRPLLIGEDDFRISGAGAQDKMIIAFV
DNQVAIPLHNTPSTHIIKPAIDELDDTVFNEFFCMRLASAMGLNTSKPDIIWLENNPFYVVERYDREFTPDGKIIRLHQE
DFCQALDIEPDVKYQNEGGPSFIDCFELINTLIKYGKMSTINKVALFDASIFNFLIGNGDAHAKNFSLLYRNLKIELAPL
YDILSTIIYSQPYQKAKMSMNVDSKCKFCQIQKRHFVELGKSIGFKEGYCIKRIESIASKILPIAKQLQQELNINNKYKS
EIYQNIIDLIEQTSKQLS
>Mature_417_residues
SNQLNVHLKDIHIGYLKKQGSKLSFNYSKEYLDSENAQPISISIPLSENEYKHDVVHPFFSGLLPDEPARSRLAKYLHIS
NKNTFELLKAIGGECAGAISVYDGQPSVDNNTENDYRILKDDEAYRLFNELKVRPLLIGEDDFRISGAGAQDKMIIAFVD
NQVAIPLHNTPSTHIIKPAIDELDDTVFNEFFCMRLASAMGLNTSKPDIIWLENNPFYVVERYDREFTPDGKIIRLHQED
FCQALDIEPDVKYQNEGGPSFIDCFELINTLIKYGKMSTINKVALFDASIFNFLIGNGDAHAKNFSLLYRNLKIELAPLY
DILSTIIYSQPYQKAKMSMNVDSKCKFCQIQKRHFVELGKSIGFKEGYCIKRIESIASKILPIAKQLQQELNINNKYKSE
IYQNIIDLIEQTSKQLS

Specific function: Unbalanced Or Excessive Expression Of Hipa Is Toxic To The Cell. [C]

COG id: COG3550

COG function: function code R; Uncharacterized protein related to capsule biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To E.coli hipA, H.influenzae HI_0665 and y4dM [H]

Homologues:

Organism=Escherichia coli, GI1787785, Length=442, Percent_Identity=30.7692307692308, Blast_Score=175, Evalue=4e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012893
- InterPro:   IPR012894
- InterPro:   IPR017508 [H]

Pfam domain/function: PF07804 HipA_C; PF07805 HipA_N [H]

EC number: NA

Molecular weight: Translated: 47723; Mature: 47592

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNQLNVHLKDIHIGYLKKQGSKLSFNYSKEYLDSENAQPISISIPLSENEYKHDVVHPF
CCCCEEEEEEEEEEEEECCCCCEEEECCCHHHHCCCCCCEEEEEEECCCCCCCHHHHHHH
FSGLLPDEPARSRLAKYLHISNKNTFELLKAIGGECAGAISVYDGQPSVDNNTENDYRIL
HHCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCEEEE
KDDEAYRLFNELKVRPLLIGEDDFRISGAGAQDKMIIAFVDNQVAIPLHNTPSTHIIKPA
CCCHHHHHHHHCCCCEEEECCCCCEEECCCCCCCEEEEEECCEEEEEECCCCCCCEECHH
IDELDDTVFNEFFCMRLASAMGLNTSKPDIIWLENNPFYVVERYDREFTPDGKIIRLHQE
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCEEEEEECCCCCCCCCCEEEECHH
DFCQALDIEPDVKYQNEGGPSFIDCFELINTLIKYGKMSTINKVALFDASIFNFLIGNGD
HHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCC
AHAKNFSLLYRNLKIELAPLYDILSTIIYSQPYQKAKMSMNVDSKCKFCQIQKRHFVELG
CCHHHHHEEEEECEEEEHHHHHHHHHHHHCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHH
KSIGFKEGYCIKRIESIASKILPIAKQLQQELNINNKYKSEIYQNIIDLIEQTSKQLS
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SNQLNVHLKDIHIGYLKKQGSKLSFNYSKEYLDSENAQPISISIPLSENEYKHDVVHPF
CCCEEEEEEEEEEEEECCCCCEEEECCCHHHHCCCCCCEEEEEEECCCCCCCHHHHHHH
FSGLLPDEPARSRLAKYLHISNKNTFELLKAIGGECAGAISVYDGQPSVDNNTENDYRIL
HHCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCEEEE
KDDEAYRLFNELKVRPLLIGEDDFRISGAGAQDKMIIAFVDNQVAIPLHNTPSTHIIKPA
CCCHHHHHHHHCCCCEEEECCCCCEEECCCCCCCEEEEEECCEEEEEECCCCCCCEECHH
IDELDDTVFNEFFCMRLASAMGLNTSKPDIIWLENNPFYVVERYDREFTPDGKIIRLHQE
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCEEEEEECCCCCCCCCCEEEECHH
DFCQALDIEPDVKYQNEGGPSFIDCFELINTLIKYGKMSTINKVALFDASIFNFLIGNGD
HHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCC
AHAKNFSLLYRNLKIELAPLYDILSTIIYSQPYQKAKMSMNVDSKCKFCQIQKRHFVELG
CCHHHHHEEEEECEEEEHHHHHHHHHHHHCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHH
KSIGFKEGYCIKRIESIASKILPIAKQLQQELNINNKYKSEIYQNIIDLIEQTSKQLS
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]