Click here to switch to the map view.

The map label for this gene is engD [H]

Identifier: 89256304

GI number: 89256304

Start: 923220

End: 924311

Strand: Reverse

Name: engD [H]

Synonym: FTL_0955

Alternate gene names: 89256304

Gene position: 924311-923220 (Counterclockwise)

Preceding gene: 89256305

Following gene: 89256303

Centisome position: 48.75

GC content: 34.71

Gene sequence:

>1092_bases
ATGGGATTTAAATGTGGTATAGTAGGTTTACCAAATGTTGGCAAATCAACTCTTTTTAATGCTCTTACAGAAGCAGGAAT
TGATGCAGAAAATTACCCTTTTTGTACAATTGATCCAAATGTTGGGATCGTTTCAGTACCAGATCAAAGACTTAATGAAT
TAGCAAAAATTGTTAAGCCAGAAAGAATAATAACGACAACAATGGAGTTTGTAGATATTGCTGGACTTGTCACTGGAGCA
AGTAAAGGCGAAGGCTTAGGTAATAAATTCCTTGCAAATATTCGTGAAACAGATGCTATAGCTCATGTTGTAAGATGCTT
TGAAGATGACAATATAATTCATGTTAGTGGTAAAGTTGATCCTATAGATGATATTAATATTATCAATATGGAGCTAATCC
TAGCTGATATCGAATATTGTGATAGAACTGTACAAAGATTCGCAAAAATGAAAAAATCAGGTGATAAAGAAGCTTTAGCT
AAAGCAGATTTTTATACTAGATTAAAAGAGCACTTAGAATCAGAGAAGCATGCAAGGACTTTTGAGATGAATGAGGATGA
AACTAAATGGCTAAAACAAACTCCTCTATTAACTAGTAAGCCTGTCCTGTATATTGCAAATGTCAATGAAAATGGTTTTG
AAAATAATCCCCTTCTAGATAAGGTTGTAGAATATGCTAAAGCTGAAAACTCAAATGTTGTGCCAGTTTGTGCTGCTATG
GAACAAGAAATTTCTCAGCTAGAAGCTGATGAAAAACTAGAATTTTTAGCTGATATGGGTCTATCAGAAACTGGTTTAGA
TAGAGTTATTAAAGCTGGTTACGCCTTACTCAACTTGCATACATATTTAACAGCAGGTGTCAAAGAAGTAAGAGCATGGA
CAATCCCTATAGGAGCAACTGCACCACAAGCGGCTGGAGTAATCCATACTGACTTTGAACGTGGTTTTATCAGAGCTGAA
GTTATCGCATACGATGATTACATTAAATATAATGGTGAAAAAGGTGCCAAAGAAGCAGGTAAAGCTCGTCTTGAAGGTAA
AGAATACATCATGAAAGATGGGGATGTAGTTAACTTTAGATTTAATGTATAG

Upstream 100 bases:

>100_bases
TATTGATAATGGTATCTGTTTTTTAGATGATATAATAAATTACAAATTAGAACCTGTAATGCAGAAGCTACATACAAAAT
AATATATAAGGAATAAAATA

Downstream 100 bases:

>100_bases
TCAAACTTTCAAAAATGTCTAAAATAATTAATAATTGTCTTATATGGTTATCAGTGCTAAGTATAGTTGGTTGTAATACT
TCATTTACTTATCCTAATTA

Product: GTP-dependent nucleic acid-binding protein EngD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 363; Mature: 362

Protein sequence:

>363_residues
MGFKCGIVGLPNVGKSTLFNALTEAGIDAENYPFCTIDPNVGIVSVPDQRLNELAKIVKPERIITTTMEFVDIAGLVTGA
SKGEGLGNKFLANIRETDAIAHVVRCFEDDNIIHVSGKVDPIDDINIINMELILADIEYCDRTVQRFAKMKKSGDKEALA
KADFYTRLKEHLESEKHARTFEMNEDETKWLKQTPLLTSKPVLYIANVNENGFENNPLLDKVVEYAKAENSNVVPVCAAM
EQEISQLEADEKLEFLADMGLSETGLDRVIKAGYALLNLHTYLTAGVKEVRAWTIPIGATAPQAAGVIHTDFERGFIRAE
VIAYDDYIKYNGEKGAKEAGKARLEGKEYIMKDGDVVNFRFNV

Sequences:

>Translated_363_residues
MGFKCGIVGLPNVGKSTLFNALTEAGIDAENYPFCTIDPNVGIVSVPDQRLNELAKIVKPERIITTTMEFVDIAGLVTGA
SKGEGLGNKFLANIRETDAIAHVVRCFEDDNIIHVSGKVDPIDDINIINMELILADIEYCDRTVQRFAKMKKSGDKEALA
KADFYTRLKEHLESEKHARTFEMNEDETKWLKQTPLLTSKPVLYIANVNENGFENNPLLDKVVEYAKAENSNVVPVCAAM
EQEISQLEADEKLEFLADMGLSETGLDRVIKAGYALLNLHTYLTAGVKEVRAWTIPIGATAPQAAGVIHTDFERGFIRAE
VIAYDDYIKYNGEKGAKEAGKARLEGKEYIMKDGDVVNFRFNV
>Mature_362_residues
GFKCGIVGLPNVGKSTLFNALTEAGIDAENYPFCTIDPNVGIVSVPDQRLNELAKIVKPERIITTTMEFVDIAGLVTGAS
KGEGLGNKFLANIRETDAIAHVVRCFEDDNIIHVSGKVDPIDDINIINMELILADIEYCDRTVQRFAKMKKSGDKEALAK
ADFYTRLKEHLESEKHARTFEMNEDETKWLKQTPLLTSKPVLYIANVNENGFENNPLLDKVVEYAKAENSNVVPVCAAME
QEISQLEADEKLEFLADMGLSETGLDRVIKAGYALLNLHTYLTAGVKEVRAWTIPIGATAPQAAGVIHTDFERGFIRAEV
IAYDDYIKYNGEKGAKEAGKARLEGKEYIMKDGDVVNFRFNV

Specific function: GTP-dependent nucleic acid-binding protein which may act as a translation factor [H]

COG id: COG0012

COG function: function code J; Predicted GTPase, probable translation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI58761500, Length=368, Percent_Identity=44.5652173913043, Blast_Score=307, Evalue=8e-84,
Organism=Homo sapiens, GI58761502, Length=218, Percent_Identity=38.5321100917431, Blast_Score=157, Evalue=2e-38,
Organism=Escherichia coli, GI1787454, Length=363, Percent_Identity=65.2892561983471, Blast_Score=501, Evalue=1e-143,
Organism=Escherichia coli, GI1789574, Length=134, Percent_Identity=27.6119402985075, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17509631, Length=365, Percent_Identity=41.3698630136986, Blast_Score=295, Evalue=2e-80,
Organism=Saccharomyces cerevisiae, GI6319499, Length=372, Percent_Identity=38.4408602150538, Blast_Score=246, Evalue=4e-66,
Organism=Saccharomyces cerevisiae, GI6321773, Length=382, Percent_Identity=36.6492146596859, Blast_Score=217, Evalue=3e-57,
Organism=Saccharomyces cerevisiae, GI6321649, Length=143, Percent_Identity=37.7622377622378, Blast_Score=77, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24640873, Length=366, Percent_Identity=40.7103825136612, Blast_Score=284, Evalue=7e-77,
Organism=Drosophila melanogaster, GI24640877, Length=366, Percent_Identity=40.7103825136612, Blast_Score=284, Evalue=7e-77,
Organism=Drosophila melanogaster, GI24640875, Length=366, Percent_Identity=40.7103825136612, Blast_Score=284, Evalue=7e-77,
Organism=Drosophila melanogaster, GI24640879, Length=325, Percent_Identity=38.1538461538462, Blast_Score=228, Evalue=3e-60,
Organism=Drosophila melanogaster, GI24585318, Length=160, Percent_Identity=31.25, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR004396
- InterPro:   IPR013029
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR012676
- InterPro:   IPR023192 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF06071 YchF-GTPase_C [H]

EC number: NA

Molecular weight: Translated: 40243; Mature: 40112

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGFKCGIVGLPNVGKSTLFNALTEAGIDAENYPFCTIDPNVGIVSVPDQRLNELAKIVKP
CCEEECEEECCCCCHHHHHHHHHHHCCCCCCCCEEEECCCCCEEECCHHHHHHHHHHHCC
ERIITTTMEFVDIAGLVTGASKGEGLGNKFLANIRETDAIAHVVRCFEDDNIIHVSGKVD
CHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCC
PIDDINIINMELILADIEYCDRTVQRFAKMKKSGDKEALAKADFYTRLKEHLESEKHART
CCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCC
FEMNEDETKWLKQTPLLTSKPVLYIANVNENGFENNPLLDKVVEYAKAENSNVVPVCAAM
CCCCCHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCEEHHHHHH
EQEISQLEADEKLEFLADMGLSETGLDRVIKAGYALLNLHTYLTAGVKEVRAWTIPIGAT
HHHHHHHCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCC
APQAAGVIHTDFERGFIRAEVIAYDDYIKYNGEKGAKEAGKARLEGKEYIMKDGDVVNFR
CCCCCCCEEECCCCCEEEEEEEEEECEEEECCCCCHHHHHHHHCCCHHHEECCCCEEEEE
FNV
ECC
>Mature Secondary Structure 
GFKCGIVGLPNVGKSTLFNALTEAGIDAENYPFCTIDPNVGIVSVPDQRLNELAKIVKP
CEEECEEECCCCCHHHHHHHHHHHCCCCCCCCEEEECCCCCEEECCHHHHHHHHHHHCC
ERIITTTMEFVDIAGLVTGASKGEGLGNKFLANIRETDAIAHVVRCFEDDNIIHVSGKVD
CHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCC
PIDDINIINMELILADIEYCDRTVQRFAKMKKSGDKEALAKADFYTRLKEHLESEKHART
CCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCC
FEMNEDETKWLKQTPLLTSKPVLYIANVNENGFENNPLLDKVVEYAKAENSNVVPVCAAM
CCCCCHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCEEHHHHHH
EQEISQLEADEKLEFLADMGLSETGLDRVIKAGYALLNLHTYLTAGVKEVRAWTIPIGAT
HHHHHHHCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCC
APQAAGVIHTDFERGFIRAEVIAYDDYIKYNGEKGAKEAGKARLEGKEYIMKDGDVVNFR
CCCCCCCEEECCCCCEEEEEEEEEECEEEECCCCCHHHHHHHHCCCHHHEECCCCEEEEE
FNV
ECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA