Click here to switch to the map view.

The map label for this gene is corC [H]

Identifier: 89256241

GI number: 89256241

Start: 861874

End: 862716

Strand: Reverse

Name: corC [H]

Synonym: FTL_0883

Alternate gene names: 89256241

Gene position: 862716-861874 (Counterclockwise)

Preceding gene: 89256242

Following gene: 89256240

Centisome position: 45.5

GC content: 30.25

Gene sequence:

>843_bases
ATGGCAGATAATAATCCTTTTATAAAAAGACTTACCTCAAGCATTTTTAATATAAAAAGTGAAGAAGCTCTTATCTATGC
TATCAATAGAGCTGCTGCTAATGAGGTTATTGATAAGACATCACAAAATATGCTAATAGGTGCGATGAAAATATCGTCAT
TAGATGTTGGTGATATTATGATATCGCATACAAAAATAGTTGCTGTAGATATGTCTATGTCTATTAGAGAGATCTTAAAA
AAGACGATAAACTCTAGTCATACGCGACTACCAGTCTACTGTGAAAACAAATCTGAAATACTAGGAATTTTACACTCAAA
AGACCTACTAAAACTAATCTTTGAAAAAGAAATTGAATCAGCTGATGATGAAGAACTCAAAGCAGAAGATATTAAAAATA
TTCTGCGCCCTGCTATCTTTATCCCTGAGACAAAAAAACTCAATGCTATGCTCAAAGATTTCAAAAATAGTCAAAATCAT
ATTGCTATAGTAGTTGATGAATATGGAGCTATTTCTGGATTAATAACTATTGAGGATGTTTTAGAAGAAATAGTCGGTGA
TATTGAGGATGAGTTTGATATCACTAGCCAAAATATAGTTAAAATGACAGATGATAAGTTTATATTAGATGCTACAACTA
CTATAGAAGACTTCAATGAATATTTTGCCACATCAATAGATGACAATAGTGATTATGACACTATTGCTGGGATGATTATT
CAAACTTTAGAGTGTTTACCTCAAAAAGGTGATAGCATTGTCGTTGATGGCTTGAAATTTACAGTTCAAGAAGCAGATAA
TAGAAAAATTATTAAAATTTTAGTCGAAAAATTTAAGAAATAA

Upstream 100 bases:

>100_bases
CACCAAGATGATCAAGAAGCCGAAGTGATGGAGAATTTAGAAATACAACTACTAGCACAGCTAGGAATAGCTAATCCATA
TATTGAACAAGAGAATCAAA

Downstream 100 bases:

>100_bases
TGAAGAAGTTAATATTTAGAATAGTTCTGCCACTATTAAGTGGTGCAATACTTACTTTAGCATTTGCACCTTTCCGTATA
GATATACTAGCTTTAATATC

Product: metal ion transporter protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 280; Mature: 279

Protein sequence:

>280_residues
MADNNPFIKRLTSSIFNIKSEEALIYAINRAAANEVIDKTSQNMLIGAMKISSLDVGDIMISHTKIVAVDMSMSIREILK
KTINSSHTRLPVYCENKSEILGILHSKDLLKLIFEKEIESADDEELKAEDIKNILRPAIFIPETKKLNAMLKDFKNSQNH
IAIVVDEYGAISGLITIEDVLEEIVGDIEDEFDITSQNIVKMTDDKFILDATTTIEDFNEYFATSIDDNSDYDTIAGMII
QTLECLPQKGDSIVVDGLKFTVQEADNRKIIKILVEKFKK

Sequences:

>Translated_280_residues
MADNNPFIKRLTSSIFNIKSEEALIYAINRAAANEVIDKTSQNMLIGAMKISSLDVGDIMISHTKIVAVDMSMSIREILK
KTINSSHTRLPVYCENKSEILGILHSKDLLKLIFEKEIESADDEELKAEDIKNILRPAIFIPETKKLNAMLKDFKNSQNH
IAIVVDEYGAISGLITIEDVLEEIVGDIEDEFDITSQNIVKMTDDKFILDATTTIEDFNEYFATSIDDNSDYDTIAGMII
QTLECLPQKGDSIVVDGLKFTVQEADNRKIIKILVEKFKK
>Mature_279_residues
ADNNPFIKRLTSSIFNIKSEEALIYAINRAAANEVIDKTSQNMLIGAMKISSLDVGDIMISHTKIVAVDMSMSIREILKK
TINSSHTRLPVYCENKSEILGILHSKDLLKLIFEKEIESADDEELKAEDIKNILRPAIFIPETKKLNAMLKDFKNSQNHI
AIVVDEYGAISGLITIEDVLEEIVGDIEDEFDITSQNIVKMTDDKFILDATTTIEDFNEYFATSIDDNSDYDTIAGMIIQ
TLECLPQKGDSIVVDGLKFTVQEADNRKIIKILVEKFKK

Specific function: Plays a role in the transport of magnesium and cobalt ions [H]

COG id: COG4535

COG function: function code P; Putative Mg2+ and Co2+ transporter CorC

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=222, Percent_Identity=30.1801801801802, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI94681046, Length=171, Percent_Identity=31.5789473684211, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI1786879, Length=273, Percent_Identity=37.3626373626374, Blast_Score=176, Evalue=2e-45,
Organism=Escherichia coli, GI145693175, Length=218, Percent_Identity=28.8990825688073, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI87082033, Length=250, Percent_Identity=26, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1790664, Length=257, Percent_Identity=25.6809338521401, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI1788119, Length=231, Percent_Identity=27.7056277056277, Blast_Score=79, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC [H]

EC number: NA

Molecular weight: Translated: 31499; Mature: 31367

Theoretical pI: Translated: 4.42; Mature: 4.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADNNPFIKRLTSSIFNIKSEEALIYAINRAAANEVIDKTSQNMLIGAMKISSLDVGDIM
CCCCCHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHCCCCEEEEEEEECCCCCCCEE
ISHTKIVAVDMSMSIREILKKTINSSHTRLPVYCENKSEILGILHSKDLLKLIFEKEIES
EECEEEEEEECCHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCC
ADDEELKAEDIKNILRPAIFIPETKKLNAMLKDFKNSQNHIAIVVDEYGAISGLITIEDV
CCCHHHHHHHHHHHHHCCEECCCHHHHHHHHHHHCCCCCEEEEEEECCCCCEEEEEHHHH
LEEIVGDIEDEFDITSQNIVKMTDDKFILDATTTIEDFNEYFATSIDDNSDYDTIAGMII
HHHHHHCCCHHCCCCCCCEEEECCCCEEEEEHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
QTLECLPQKGDSIVVDGLKFTVQEADNRKIIKILVEKFKK
HHHHHCCCCCCEEEEECEEEEEECCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
ADNNPFIKRLTSSIFNIKSEEALIYAINRAAANEVIDKTSQNMLIGAMKISSLDVGDIM
CCCCHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHCCCCEEEEEEEECCCCCCCEE
ISHTKIVAVDMSMSIREILKKTINSSHTRLPVYCENKSEILGILHSKDLLKLIFEKEIES
EECEEEEEEECCHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCC
ADDEELKAEDIKNILRPAIFIPETKKLNAMLKDFKNSQNHIAIVVDEYGAISGLITIEDV
CCCHHHHHHHHHHHHHCCEECCCHHHHHHHHHHHCCCCCEEEEEEECCCCCEEEEEHHHH
LEEIVGDIEDEFDITSQNIVKMTDDKFILDATTTIEDFNEYFATSIDDNSDYDTIAGMII
HHHHHHCCCHHCCCCCCCEEEECCCCEEEEEHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
QTLECLPQKGDSIVVDGLKFTVQEADNRKIIKILVEKFKK
HHHHHCCCCCCEEEEECEEEEEECCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12522265 [H]