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The map label for this gene is tyrP-A [H]

Identifier: 89256195

GI number: 89256195

Start: 818006

End: 818743

Strand: Reverse

Name: tyrP-A [H]

Synonym: FTL_0835

Alternate gene names: 89256195

Gene position: 818743-818006 (Counterclockwise)

Preceding gene: 89256196

Following gene: 89256194

Centisome position: 43.18

GC content: 26.56

Gene sequence:

>738_bases
ATGTTAGCAGCTTATATATCAGCTATAGGTTCATCCTTTGAAAGCTTATTGAATATAAATTATATAGTTATTGAGATATG
CTTTGTTATTATTTTTGGTGGTTTTATTTTAAAAGGTACAGGCTCTGCCGAATGGCTAAATAGAATTTTTCTAAGTCTAA
AATTAATAATCATACTTTTTACTATAATATTGCTATTTAGATCAATACATCTAACAAATCTAGGTAGTTATAGTTTTAGT
AATTTCAAACAACTAATAATAGCTTTACCTATTTTAGCCACAACATTTTCAGCACACATAATAATCCCTAGTGTTGTAAA
TTATGTAGGACCACATCCAAAACATATTAGAAGAATTATCATAATTGCATCATTTATCATATTAGCAATATACATATGCT
GGATAATCTCAATATTTGGTAATATCGCAATTTATGGTAGTAAAAATAGTTTCGCTGAAATACTTAAATCGCTTAGTTCT
GAGGATAGTGTCACTCAGCTTATATATATTCTCAAAGCAAATATAAAATCCTTAGAAATTATAAGTTTTATATACTCTTT
TATTACAATATCAGTAACTACAGCTTTTATAACCCTTTCATTAGCACTAAAAGACTTAATATTGGATAGGTTTAAAATGG
CTAATTTATTATTTCAAGAAACTTTTCTTAATTGCATTATCTATTGTTGGCTTATTCTCACTAATAATGCTTGTATCCTG
TCCTTTATATATGGTTAG

Upstream 100 bases:

>100_bases
CATTTTGAGAAAGGTATCAGTTATCTAGGCTTAGCACATAAACTTTTTAAAAAAACCTGGGATTGCTGTCTATATTTGTG
CATTTGGGATACTTTATGGT

Downstream 100 bases:

>100_bases
AATTTTACGTAAGCGTAATTATCAAATAATTTACAAATCTATGCAAAATAGTAAATTCAATAATCTTGCCCTACTTAGTG
CAGCTGTAATAATTATCTTT

Product: aromatic amino acid HAAP transporter

Products: Proton [Cytoplasm]; L-tyrosine [Cytoplasm] [C]

Alternate protein names: Tyrosine permease 1 [H]

Number of amino acids: Translated: 245; Mature: 245

Protein sequence:

>245_residues
MLAAYISAIGSSFESLLNINYIVIEICFVIIFGGFILKGTGSAEWLNRIFLSLKLIIILFTIILLFRSIHLTNLGSYSFS
NFKQLIIALPILATTFSAHIIIPSVVNYVGPHPKHIRRIIIIASFIILAIYICWIISIFGNIAIYGSKNSFAEILKSLSS
EDSVTQLIYILKANIKSLEIISFIYSFITISVTTAFITLSLALKDLILDRFKMANLLFQETFLNCIIYCWLILTNNACIL
SFIYG

Sequences:

>Translated_245_residues
MLAAYISAIGSSFESLLNINYIVIEICFVIIFGGFILKGTGSAEWLNRIFLSLKLIIILFTIILLFRSIHLTNLGSYSFS
NFKQLIIALPILATTFSAHIIIPSVVNYVGPHPKHIRRIIIIASFIILAIYICWIISIFGNIAIYGSKNSFAEILKSLSS
EDSVTQLIYILKANIKSLEIISFIYSFITISVTTAFITLSLALKDLILDRFKMANLLFQETFLNCIIYCWLILTNNACIL
SFIYG
>Mature_245_residues
MLAAYISAIGSSFESLLNINYIVIEICFVIIFGGFILKGTGSAEWLNRIFLSLKLIIILFTIILLFRSIHLTNLGSYSFS
NFKQLIIALPILATTFSAHIIIPSVVNYVGPHPKHIRRIIIIASFIILAIYICWIISIFGNIAIYGSKNSFAEILKSLSS
EDSVTQLIYILKANIKSLEIISFIYSFITISVTTAFITLSLALKDLILDRFKMANLLFQETFLNCIIYCWLILTNNACIL
SFIYG

Specific function: Involved in transporting tyrosine across the cytoplasmic membrane [H]

COG id: COG0814

COG function: function code E; Amino acid permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid/polyamine transporter 2 family. Mtr/TnaB/TyrP permease subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788218, Length=219, Percent_Identity=27.3972602739726, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1789552, Length=266, Percent_Identity=25.5639097744361, Blast_Score=61, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002091
- InterPro:   IPR013061
- InterPro:   IPR013059
- InterPro:   IPR018227 [H]

Pfam domain/function: PF03222 Trp_Tyr_perm [H]

EC number: NA

Molecular weight: Translated: 27544; Mature: 27544

Theoretical pI: Translated: 8.91; Mature: 8.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAAYISAIGSSFESLLNINYIVIEICFVIIFGGFILKGTGSAEWLNRIFLSLKLIIILF
CHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHH
TIILLFRSIHLTNLGSYSFSNFKQLIIALPILATTFSAHIIIPSVVNYVGPHPKHIRRII
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
IIASFIILAIYICWIISIFGNIAIYGSKNSFAEILKSLSSEDSVTQLIYILKANIKSLEI
HHHHHHHHHHHHHHHHHHHHCEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHH
ISFIYSFITISVTTAFITLSLALKDLILDRFKMANLLFQETFLNCIIYCWLILTNNACIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
SFIYG
EEECC
>Mature Secondary Structure
MLAAYISAIGSSFESLLNINYIVIEICFVIIFGGFILKGTGSAEWLNRIFLSLKLIIILF
CHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHH
TIILLFRSIHLTNLGSYSFSNFKQLIIALPILATTFSAHIIIPSVVNYVGPHPKHIRRII
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
IIASFIILAIYICWIISIFGNIAIYGSKNSFAEILKSLSSEDSVTQLIYILKANIKSLEI
HHHHHHHHHHHHHHHHHHHHCEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHH
ISFIYSFITISVTTAFITLSLALKDLILDRFKMANLLFQETFLNCIIYCWLILTNNACIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
SFIYG
EEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-tyrosine [Periplasm] [C]

Specific reaction: Proton [Periplasm] + L-tyrosine [Periplasm] = Proton [Cytoplasm] + L-tyrosine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]