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The map label for this gene is putA [H]

Identifier: 89256175

GI number: 89256175

Start: 789223

End: 793287

Strand: Direct

Name: putA [H]

Synonym: FTL_0805

Alternate gene names: 89256175

Gene position: 789223-793287 (Clockwise)

Preceding gene: 89256174

Following gene: 89256176

Centisome position: 41.63

GC content: 35.65

Gene sequence:

>4065_bases
ATGAATGACTTACTAAATCACTCAGGAGAATATCCTATTTCTAAAGAAATAATGAATATATATAAATATTGGCTTATCGA
TGAAAAAGAAGCCATGACAAAGCTTGTTGAAAAAGCTCATATGTCAAGCGTTCAAAAGGCACAAGTTAGAGAAAGGGCTT
ATGGCTTAGTAGAAAAAGTCAGAAAGAATAGACTCAAAAAGTCTGGCATTGATGCGTTTATGATCGAGTATGACTTATCA
TCAGAAGAAGGGGTAGTGCTGATGTGTTTAGCTGAAGCGCTGCTAAGAGTACCTGATAAATATACTATTGATCTGCTTAT
CAAAGATAAGCTTACAAGTGCTGCGTGGAAAAACCATGTTGGTATGGAAAAGCATCTATTTGTTAATGCTGCGACATGGA
GTTTGATGTTAACTGGTAAAATTCTTAAAGATCCGCATCGTTCTTATAGAAAAGTTTTTCAAAATTTTCTTAAAAAAACT
AGTGAGCCAGTAATTCGTCAAGCAATGAAACAAGCAATGAAAATTGTTGGTAAGCAATATGTACTTGGTGAAACTATCGA
AGAAGCTCTAAAGGTATCAGAAGCTAAAGTAGCCAGAGGCTATAGCTATTCTTATGATATGCTTGGTGAAGCTGCAATGA
CAATGGATGATGCTGAGTACTATTATAGTCAGTATCTTCATGCAATACATGAGTTAGCTAAGTATGCTACAAATACGGAA
ATCAAAAAAAATCCAGGAATTTCTATCAAATTATCTGCTTTACATCCACGCTATGAGGTTGCAAAGCACCAAAGAGTTCA
TACAGAATTATATCCAAAACTGCTTAAGCTTACGCAATTAGCAAAAGATTATAATGTTGGGATGAATATCGATGCTGAAG
AAACAGAAAGATTACAAATATCATTAGAACTAGTAGAAAGACTAGCTCATGAGCCATCTTTAGAAGGTTTTAATGGTATT
GGTATTGTTGTTCAGGCATACCAAAAAAGAGCTCCTTATGTATTAGATTATTTAGCAAATCTTGCTAAGAAAACTAATAG
AAGATTTATGATCCGCTTAGTTAAGGGGGCGTATTGGGATGCCGAAATTAAGCATGCGCAAGAGCAAGGTTTAGCAGGTT
ATCCAGTATTTACGCGTAAATATCACACAGACGTCTCATATCAGGCTTGTGTTAAACAGCTTTTTGAGAATCATCAATAT
ATCTATCCTCAGTTTGCAACGCATAATGCTCAGACTGTCGCTGTAGTATTTGAGTTAGCTAATGGTAATAGAGATTTTGA
ATTTCAGTGTTTACATGGTATGGGCGATGCGCTATATGACAATGTCGTTGGTAAAGAAGGCTATGAAGATATTCCATGTA
GAATATATGCACCAGTTGGTGGTCATAAGCATCTTTTAGCATATCTAGTAAGAAGACTGCTAGAAAATGGTGCTAATAGC
TCATTCGTAAATAGAATAGTAGACGAGAATTTACCTATTGAAGAATTAATAGAGGATCCTGTTAAAAAAGCTATCGATCA
TGGTTGTGGTCAGCATCCTAATATTCCTTATCCAAAAGATATAGTCTCACCAAGATTAAATTCACAAGGTCATAATACTA
ATGATTTTGCTGTTTTGGCTGATATGTATAAGCAAATAGAAAAATATACGCACAAAAATACATATAAAGCAAAACCGATA
GTTTCTGGTATTGATCTTGATAAAACAATTACTGAAAGTGTTATAAATCCAAATACTAATGAAGTCATCGGTAGCGTAAT
CAATGCTGATGCTAAAATTGCTAAAAGAGCACTAAAAAATGCTCAAAGTGCATTTGAAGAGTGGAGTAATACACCAGCAA
CAAAAAGAGCAGATATTCTAGAGAAATTTGCTGATCTTTTAGAACAAGATACTAATAAATTTATTGCTATAGCAATGATT
GAAGCTGGTAAAACCTTGGCTAATGCTATAGATGAGGTTAGAGAGGCTGTAGATTTTTGTCGTTATTATGCTGCACAAGC
TAGAAAAGAATTTAATGGTCCTATTGAATTGCCAGCTTTATCAGATCATCTTAAGCAGATAGAGTTTACCGGTCGCGGAG
CTATGGTATGTATTAGCCCTTGGAATTTCCCATTGGCAATATTCTTAGGACAGATAACAGCTGTTTTAGCAGCTGGTAAT
ACAGTAGTTGCTAAACCAGCAGAGCAGACGCCAATAATAGCTTATAAGGCTGTTAAGCTTTTATTTAAAGCTGGTTTACC
TAAAAATGTTTTACAATTTACGCCTGGTGATGGTGCAACAGTTGGTAGTGCTCTGGTTAAGAGCCCAGTATGTAAAGGTG
TGATTTTCACAGGCTCTACAGAGGTTGCAGCTATTATAAATCAGACTTTGGCAAACAAATCTAGTGAAATAGTACCATTT
ATTGCTGAGACAGGTGGACAAAACGCTATGATTGTTGACTCATCATCGCTTCCTGAGCAGGTTACCGCAGATGTGATACG
TTCAGCTTTTGATAGCGCGGGACAACGCTGTTCAGCATTACGTATCTTATGTCTTCAAGAAGATATCGCTGATAACTATA
TTAAGATGATAGTTGGTGCAATGAAAGAACTTAAAATAGGCGATTCTAAATATATTGATACTGATGTTGGTCCTGTGATC
GATAAAGAGGCTGCTGATAATCTAAATGCGTATATTGAAGAGAAAAAAAGCCAGTTTAAGCTTATATATCAATCTCAACC
TAACCAAGATACACAAAAGGGCACATTTGTGATGCCTACTGCTTTTGAGATAGATAAAATATCTGATTTGGGTAGAGAGC
AGTTTGGTCCAATTTTACATATCTTGCGCTTTAAGGCTAATCAACTAGATAAGCTTATCAACGACATCAATGCTACAGGA
TATGGTCTAACAGCCGGTGTGCATAGTCGAATTAATGAAGTGATGAACTATGTTAAAAATAACCTTAAAGCTGGTAATAT
CTATGTAAATAGGAATATTGTTGGTGCTGTTGTTGGTGTCCAACCATTTGGTGGTCAAGGCAAATCTGGAACAGGTCCTA
AAGCTGGCGGCCCTTATTATATGCATCGTTTAGCTAATGAAAAATTATCAGGAGTAGGTGCCGTTGAAGAGATCTACAAT
CCTGAAAAAATAGCTGAATATGAAAAGCAGACTAACAAGCTTATCAAAGATAAATATACTATCACAAATATTGTTGCTGG
TGAGAAAGCTAAAAAAGATAAATATACTAATCTTAAAGCAGCAAATGGTAAAACGATTGGTAAGAAATATGTAGCTTCTG
TGAATACTGTAGATAATGCTATAGAAATTGCTAGTAAAGAGGTAGAGATATGGAATCATGTTAATGCTGAACAAAGAGCT
GCCACTATTGAGAAATTCTTAGAACTATTAGAGAAAGAGCGTTATTTGATAGCTTCATCTCTTGTAGTGGAGTCAAATAT
TTCAGTTGAGGATGCTCATATCCAAATAGATAAAACTATTCAGCAGGTGGCATACTATTGCCTACAAGCTAAAAAAGAGT
TTGCTCATCCACAACTTTTACCTGGACCTACAGGAGAGATTGATGAGTTAAGCTTAAAAGGTCGAGGTGTTGTAGTAAGT
ATGTGTTCAAGTTCTGATTTACTGATCAGATTTGTTGGTCAAACTGCTGCGGCTTTACTAGCGGGTAATACTGTAGTAGC
TAAGCCAGCATATACCGGTAATTTAACTGCTTATAATATTGTTAAATTAATGTTAAAAGCGGGAATAGACTCTAAAGTAC
TTCATCTAGTGTTGTCAGATGATGAAGAGATAACATCAGCTTTATTATTTAATAGTAAGGTTGCACTAGTTTCCTTCTCT
GGTAGTGTTTCTGCGGTTAAACAGGTTCATCAGGCTTTAGTATTACGTAGAGGTGCGATTATACCTTTTGTTGCTGAGAG
TATTGCTAAAAATGGCAAATGTACAAGCTTAGCAATAGAAACAGCTTCACCATTGTATTTACGCAGGTTTGTAGTTGAAA
AAACCGTAAGTGTTGATACAACTGCCTCTGGTGGTAATGCTTCTTTAATGAGCCTAGAAGAATAA

Upstream 100 bases:

>100_bases
GTTACTCCGCCACAAAGATATCAACAACTTATAGACAAAATTATCAAAGAAAAGAAAAAATTTAATCAAACTAAATTAAA
GTAGCTAAAAGGTGTGTTAT

Downstream 100 bases:

>100_bases
AAAATATTGCAAACTTATTTTCTTGATGATAATTTAAATCTTAGATTATTAACTTTCTACTAACTTTATAGGTTAGTCAT
TATCAAATAATCACAGTGAA

Product: bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase

Products: NA

Alternate protein names: Proline dehydrogenase; Proline oxidase; Delta-1-pyrroline-5-carboxylate dehydrogenase; P5C dehydrogenase [H]

Number of amino acids: Translated: 1354; Mature: 1354

Protein sequence:

>1354_residues
MNDLLNHSGEYPISKEIMNIYKYWLIDEKEAMTKLVEKAHMSSVQKAQVRERAYGLVEKVRKNRLKKSGIDAFMIEYDLS
SEEGVVLMCLAEALLRVPDKYTIDLLIKDKLTSAAWKNHVGMEKHLFVNAATWSLMLTGKILKDPHRSYRKVFQNFLKKT
SEPVIRQAMKQAMKIVGKQYVLGETIEEALKVSEAKVARGYSYSYDMLGEAAMTMDDAEYYYSQYLHAIHELAKYATNTE
IKKNPGISIKLSALHPRYEVAKHQRVHTELYPKLLKLTQLAKDYNVGMNIDAEETERLQISLELVERLAHEPSLEGFNGI
GIVVQAYQKRAPYVLDYLANLAKKTNRRFMIRLVKGAYWDAEIKHAQEQGLAGYPVFTRKYHTDVSYQACVKQLFENHQY
IYPQFATHNAQTVAVVFELANGNRDFEFQCLHGMGDALYDNVVGKEGYEDIPCRIYAPVGGHKHLLAYLVRRLLENGANS
SFVNRIVDENLPIEELIEDPVKKAIDHGCGQHPNIPYPKDIVSPRLNSQGHNTNDFAVLADMYKQIEKYTHKNTYKAKPI
VSGIDLDKTITESVINPNTNEVIGSVINADAKIAKRALKNAQSAFEEWSNTPATKRADILEKFADLLEQDTNKFIAIAMI
EAGKTLANAIDEVREAVDFCRYYAAQARKEFNGPIELPALSDHLKQIEFTGRGAMVCISPWNFPLAIFLGQITAVLAAGN
TVVAKPAEQTPIIAYKAVKLLFKAGLPKNVLQFTPGDGATVGSALVKSPVCKGVIFTGSTEVAAIINQTLANKSSEIVPF
IAETGGQNAMIVDSSSLPEQVTADVIRSAFDSAGQRCSALRILCLQEDIADNYIKMIVGAMKELKIGDSKYIDTDVGPVI
DKEAADNLNAYIEEKKSQFKLIYQSQPNQDTQKGTFVMPTAFEIDKISDLGREQFGPILHILRFKANQLDKLINDINATG
YGLTAGVHSRINEVMNYVKNNLKAGNIYVNRNIVGAVVGVQPFGGQGKSGTGPKAGGPYYMHRLANEKLSGVGAVEEIYN
PEKIAEYEKQTNKLIKDKYTITNIVAGEKAKKDKYTNLKAANGKTIGKKYVASVNTVDNAIEIASKEVEIWNHVNAEQRA
ATIEKFLELLEKERYLIASSLVVESNISVEDAHIQIDKTIQQVAYYCLQAKKEFAHPQLLPGPTGEIDELSLKGRGVVVS
MCSSSDLLIRFVGQTAAALLAGNTVVAKPAYTGNLTAYNIVKLMLKAGIDSKVLHLVLSDDEEITSALLFNSKVALVSFS
GSVSAVKQVHQALVLRRGAIIPFVAESIAKNGKCTSLAIETASPLYLRRFVVEKTVSVDTTASGGNASLMSLEE

Sequences:

>Translated_1354_residues
MNDLLNHSGEYPISKEIMNIYKYWLIDEKEAMTKLVEKAHMSSVQKAQVRERAYGLVEKVRKNRLKKSGIDAFMIEYDLS
SEEGVVLMCLAEALLRVPDKYTIDLLIKDKLTSAAWKNHVGMEKHLFVNAATWSLMLTGKILKDPHRSYRKVFQNFLKKT
SEPVIRQAMKQAMKIVGKQYVLGETIEEALKVSEAKVARGYSYSYDMLGEAAMTMDDAEYYYSQYLHAIHELAKYATNTE
IKKNPGISIKLSALHPRYEVAKHQRVHTELYPKLLKLTQLAKDYNVGMNIDAEETERLQISLELVERLAHEPSLEGFNGI
GIVVQAYQKRAPYVLDYLANLAKKTNRRFMIRLVKGAYWDAEIKHAQEQGLAGYPVFTRKYHTDVSYQACVKQLFENHQY
IYPQFATHNAQTVAVVFELANGNRDFEFQCLHGMGDALYDNVVGKEGYEDIPCRIYAPVGGHKHLLAYLVRRLLENGANS
SFVNRIVDENLPIEELIEDPVKKAIDHGCGQHPNIPYPKDIVSPRLNSQGHNTNDFAVLADMYKQIEKYTHKNTYKAKPI
VSGIDLDKTITESVINPNTNEVIGSVINADAKIAKRALKNAQSAFEEWSNTPATKRADILEKFADLLEQDTNKFIAIAMI
EAGKTLANAIDEVREAVDFCRYYAAQARKEFNGPIELPALSDHLKQIEFTGRGAMVCISPWNFPLAIFLGQITAVLAAGN
TVVAKPAEQTPIIAYKAVKLLFKAGLPKNVLQFTPGDGATVGSALVKSPVCKGVIFTGSTEVAAIINQTLANKSSEIVPF
IAETGGQNAMIVDSSSLPEQVTADVIRSAFDSAGQRCSALRILCLQEDIADNYIKMIVGAMKELKIGDSKYIDTDVGPVI
DKEAADNLNAYIEEKKSQFKLIYQSQPNQDTQKGTFVMPTAFEIDKISDLGREQFGPILHILRFKANQLDKLINDINATG
YGLTAGVHSRINEVMNYVKNNLKAGNIYVNRNIVGAVVGVQPFGGQGKSGTGPKAGGPYYMHRLANEKLSGVGAVEEIYN
PEKIAEYEKQTNKLIKDKYTITNIVAGEKAKKDKYTNLKAANGKTIGKKYVASVNTVDNAIEIASKEVEIWNHVNAEQRA
ATIEKFLELLEKERYLIASSLVVESNISVEDAHIQIDKTIQQVAYYCLQAKKEFAHPQLLPGPTGEIDELSLKGRGVVVS
MCSSSDLLIRFVGQTAAALLAGNTVVAKPAYTGNLTAYNIVKLMLKAGIDSKVLHLVLSDDEEITSALLFNSKVALVSFS
GSVSAVKQVHQALVLRRGAIIPFVAESIAKNGKCTSLAIETASPLYLRRFVVEKTVSVDTTASGGNASLMSLEE
>Mature_1354_residues
MNDLLNHSGEYPISKEIMNIYKYWLIDEKEAMTKLVEKAHMSSVQKAQVRERAYGLVEKVRKNRLKKSGIDAFMIEYDLS
SEEGVVLMCLAEALLRVPDKYTIDLLIKDKLTSAAWKNHVGMEKHLFVNAATWSLMLTGKILKDPHRSYRKVFQNFLKKT
SEPVIRQAMKQAMKIVGKQYVLGETIEEALKVSEAKVARGYSYSYDMLGEAAMTMDDAEYYYSQYLHAIHELAKYATNTE
IKKNPGISIKLSALHPRYEVAKHQRVHTELYPKLLKLTQLAKDYNVGMNIDAEETERLQISLELVERLAHEPSLEGFNGI
GIVVQAYQKRAPYVLDYLANLAKKTNRRFMIRLVKGAYWDAEIKHAQEQGLAGYPVFTRKYHTDVSYQACVKQLFENHQY
IYPQFATHNAQTVAVVFELANGNRDFEFQCLHGMGDALYDNVVGKEGYEDIPCRIYAPVGGHKHLLAYLVRRLLENGANS
SFVNRIVDENLPIEELIEDPVKKAIDHGCGQHPNIPYPKDIVSPRLNSQGHNTNDFAVLADMYKQIEKYTHKNTYKAKPI
VSGIDLDKTITESVINPNTNEVIGSVINADAKIAKRALKNAQSAFEEWSNTPATKRADILEKFADLLEQDTNKFIAIAMI
EAGKTLANAIDEVREAVDFCRYYAAQARKEFNGPIELPALSDHLKQIEFTGRGAMVCISPWNFPLAIFLGQITAVLAAGN
TVVAKPAEQTPIIAYKAVKLLFKAGLPKNVLQFTPGDGATVGSALVKSPVCKGVIFTGSTEVAAIINQTLANKSSEIVPF
IAETGGQNAMIVDSSSLPEQVTADVIRSAFDSAGQRCSALRILCLQEDIADNYIKMIVGAMKELKIGDSKYIDTDVGPVI
DKEAADNLNAYIEEKKSQFKLIYQSQPNQDTQKGTFVMPTAFEIDKISDLGREQFGPILHILRFKANQLDKLINDINATG
YGLTAGVHSRINEVMNYVKNNLKAGNIYVNRNIVGAVVGVQPFGGQGKSGTGPKAGGPYYMHRLANEKLSGVGAVEEIYN
PEKIAEYEKQTNKLIKDKYTITNIVAGEKAKKDKYTNLKAANGKTIGKKYVASVNTVDNAIEIASKEVEIWNHVNAEQRA
ATIEKFLELLEKERYLIASSLVVESNISVEDAHIQIDKTIQQVAYYCLQAKKEFAHPQLLPGPTGEIDELSLKGRGVVVS
MCSSSDLLIRFVGQTAAALLAGNTVVAKPAYTGNLTAYNIVKLMLKAGIDSKVLHLVLSDDEEITSALLFNSKVALVSFS
GSVSAVKQVHQALVLRRGAIIPFVAESIAKNGKCTSLAIETASPLYLRRFVVEKTVSVDTTASGGNASLMSLEE

Specific function: Oxidizes proline to glutamate for use as a carbon and nitrogen source and also function as a transcriptional repressor of the put operon [H]

COG id: COG4230

COG function: function code C; Delta 1-pyrroline-5-carboxylate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI21361176, Length=450, Percent_Identity=33.1111111111111, Blast_Score=196, Evalue=1e-49,
Organism=Homo sapiens, GI25777730, Length=455, Percent_Identity=32.0879120879121, Blast_Score=196, Evalue=2e-49,
Organism=Homo sapiens, GI153266822, Length=454, Percent_Identity=31.057268722467, Blast_Score=196, Evalue=2e-49,
Organism=Homo sapiens, GI25777732, Length=454, Percent_Identity=31.4977973568282, Blast_Score=195, Evalue=3e-49,
Organism=Homo sapiens, GI238814322, Length=465, Percent_Identity=31.8279569892473, Blast_Score=192, Evalue=3e-48,
Organism=Homo sapiens, GI21614513, Length=469, Percent_Identity=32.409381663113, Blast_Score=191, Evalue=5e-48,
Organism=Homo sapiens, GI25777736, Length=477, Percent_Identity=29.769392033543, Blast_Score=188, Evalue=4e-47,
Organism=Homo sapiens, GI25777734, Length=477, Percent_Identity=29.769392033543, Blast_Score=188, Evalue=4e-47,
Organism=Homo sapiens, GI238859541, Length=477, Percent_Identity=29.769392033543, Blast_Score=187, Evalue=4e-47,
Organism=Homo sapiens, GI12007648, Length=452, Percent_Identity=31.4159292035398, Blast_Score=187, Evalue=6e-47,
Organism=Homo sapiens, GI25777724, Length=450, Percent_Identity=30.6666666666667, Blast_Score=178, Evalue=3e-44,
Organism=Homo sapiens, GI25777728, Length=408, Percent_Identity=30.6372549019608, Blast_Score=164, Evalue=6e-40,
Organism=Homo sapiens, GI115387104, Length=458, Percent_Identity=27.7292576419214, Blast_Score=155, Evalue=4e-37,
Organism=Homo sapiens, GI4507229, Length=463, Percent_Identity=28.0777537796976, Blast_Score=154, Evalue=4e-37,
Organism=Homo sapiens, GI25952152, Length=445, Percent_Identity=30.561797752809, Blast_Score=154, Evalue=8e-37,
Organism=Homo sapiens, GI188035924, Length=463, Percent_Identity=26.5658747300216, Blast_Score=146, Evalue=1e-34,
Organism=Homo sapiens, GI310128103, Length=463, Percent_Identity=26.5658747300216, Blast_Score=145, Evalue=2e-34,
Organism=Homo sapiens, GI310128093, Length=453, Percent_Identity=26.4900662251656, Blast_Score=145, Evalue=3e-34,
Organism=Homo sapiens, GI25777721, Length=476, Percent_Identity=27.5210084033613, Blast_Score=144, Evalue=6e-34,
Organism=Homo sapiens, GI25777726, Length=450, Percent_Identity=27.7777777777778, Blast_Score=136, Evalue=1e-31,
Organism=Homo sapiens, GI11095441, Length=393, Percent_Identity=25.9541984732824, Blast_Score=117, Evalue=7e-26,
Organism=Homo sapiens, GI310128091, Length=401, Percent_Identity=26.1845386533666, Blast_Score=116, Evalue=1e-25,
Organism=Homo sapiens, GI310128087, Length=283, Percent_Identity=28.6219081272085, Blast_Score=111, Evalue=5e-24,
Organism=Homo sapiens, GI310128101, Length=211, Percent_Identity=29.8578199052133, Blast_Score=94, Evalue=1e-18,
Organism=Homo sapiens, GI310128099, Length=211, Percent_Identity=29.8578199052133, Blast_Score=93, Evalue=1e-18,
Organism=Homo sapiens, GI4502043, Length=324, Percent_Identity=25.3086419753086, Blast_Score=91, Evalue=1e-17,
Organism=Homo sapiens, GI238814371, Length=324, Percent_Identity=25.3086419753086, Blast_Score=91, Evalue=1e-17,
Organism=Homo sapiens, GI71773324, Length=331, Percent_Identity=24.773413897281, Blast_Score=90, Evalue=1e-17,
Organism=Homo sapiens, GI206597441, Length=429, Percent_Identity=24.4755244755245, Blast_Score=89, Evalue=2e-17,
Organism=Homo sapiens, GI206597439, Length=429, Percent_Identity=24.4755244755245, Blast_Score=89, Evalue=2e-17,
Organism=Homo sapiens, GI22907049, Length=429, Percent_Identity=24.4755244755245, Blast_Score=89, Evalue=2e-17,
Organism=Homo sapiens, GI301500698, Length=269, Percent_Identity=28.6245353159851, Blast_Score=87, Evalue=1e-16,
Organism=Homo sapiens, GI73695881, Length=357, Percent_Identity=24.6498599439776, Blast_Score=86, Evalue=2e-16,
Organism=Homo sapiens, GI73695879, Length=357, Percent_Identity=24.6498599439776, Blast_Score=86, Evalue=2e-16,
Organism=Homo sapiens, GI310128089, Length=337, Percent_Identity=26.1127596439169, Blast_Score=84, Evalue=1e-15,
Organism=Homo sapiens, GI223972651, Length=743, Percent_Identity=22.0726783310902, Blast_Score=81, Evalue=8e-15,
Organism=Homo sapiens, GI73466520, Length=330, Percent_Identity=24.2424242424242, Blast_Score=79, Evalue=4e-14,
Organism=Homo sapiens, GI310128095, Length=314, Percent_Identity=25.1592356687898, Blast_Score=79, Evalue=4e-14,
Organism=Homo sapiens, GI4557303, Length=330, Percent_Identity=24.2424242424242, Blast_Score=78, Evalue=5e-14,
Organism=Homo sapiens, GI310128097, Length=250, Percent_Identity=25.2, Blast_Score=69, Evalue=4e-11,
Organism=Escherichia coli, GI1787250, Length=1026, Percent_Identity=50.3898635477583, Blast_Score=1003, Evalue=0.0,
Organism=Escherichia coli, GI87081896, Length=468, Percent_Identity=29.0598290598291, Blast_Score=182, Evalue=2e-46,
Organism=Escherichia coli, GI1787558, Length=451, Percent_Identity=30.1552106430155, Blast_Score=175, Evalue=2e-44,
Organism=Escherichia coli, GI1789015, Length=470, Percent_Identity=28.0851063829787, Blast_Score=173, Evalue=8e-44,
Organism=Escherichia coli, GI1787715, Length=446, Percent_Identity=30.0448430493274, Blast_Score=160, Evalue=5e-40,
Organism=Escherichia coli, GI1788042, Length=447, Percent_Identity=28.6353467561521, Blast_Score=156, Evalue=8e-39,
Organism=Escherichia coli, GI1787684, Length=459, Percent_Identity=28.7581699346405, Blast_Score=152, Evalue=2e-37,
Organism=Escherichia coli, GI1786504, Length=462, Percent_Identity=27.9220779220779, Blast_Score=149, Evalue=8e-37,
Organism=Escherichia coli, GI87082295, Length=457, Percent_Identity=25.8205689277899, Blast_Score=129, Evalue=2e-30,
Organism=Escherichia coli, GI87081926, Length=446, Percent_Identity=25.7847533632287, Blast_Score=113, Evalue=9e-26,
Organism=Caenorhabditis elegans, GI17534447, Length=480, Percent_Identity=31.6666666666667, Blast_Score=185, Evalue=1e-46,
Organism=Caenorhabditis elegans, GI25144435, Length=454, Percent_Identity=30.8370044052863, Blast_Score=177, Evalue=5e-44,
Organism=Caenorhabditis elegans, GI133930964, Length=556, Percent_Identity=28.2374100719424, Blast_Score=174, Evalue=4e-43,
Organism=Caenorhabditis elegans, GI115532534, Length=408, Percent_Identity=32.5980392156863, Blast_Score=172, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI17562198, Length=461, Percent_Identity=30.3687635574837, Blast_Score=168, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI32564736, Length=409, Percent_Identity=30.5623471882641, Blast_Score=158, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI115534176, Length=462, Percent_Identity=29.004329004329, Blast_Score=157, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI17534119, Length=474, Percent_Identity=27.2151898734177, Blast_Score=152, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI25143874, Length=458, Percent_Identity=28.3842794759825, Blast_Score=148, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI25143876, Length=458, Percent_Identity=28.3842794759825, Blast_Score=148, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI71995606, Length=471, Percent_Identity=28.0254777070064, Blast_Score=144, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI32564151, Length=427, Percent_Identity=30.2107728337237, Blast_Score=142, Evalue=9e-34,
Organism=Caenorhabditis elegans, GI17551164, Length=449, Percent_Identity=27.6169265033408, Blast_Score=142, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI71986308, Length=468, Percent_Identity=28.2051282051282, Blast_Score=135, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI71995613, Length=422, Percent_Identity=28.1990521327014, Blast_Score=134, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI71990744, Length=326, Percent_Identity=31.2883435582822, Blast_Score=114, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI17564084, Length=338, Percent_Identity=26.6272189349112, Blast_Score=100, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI25146391, Length=344, Percent_Identity=24.7093023255814, Blast_Score=85, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI32566756, Length=344, Percent_Identity=25, Blast_Score=84, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI25146394, Length=344, Percent_Identity=25, Blast_Score=84, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6323821, Length=460, Percent_Identity=31.5217391304348, Blast_Score=178, Evalue=7e-45,
Organism=Saccharomyces cerevisiae, GI6321826, Length=477, Percent_Identity=30.8176100628931, Blast_Score=175, Evalue=5e-44,
Organism=Saccharomyces cerevisiae, GI6323822, Length=459, Percent_Identity=30.5010893246187, Blast_Score=174, Evalue=8e-44,
Organism=Saccharomyces cerevisiae, GI6325196, Length=461, Percent_Identity=30.3687635574837, Blast_Score=166, Evalue=2e-41,
Organism=Saccharomyces cerevisiae, GI6320917, Length=457, Percent_Identity=30.1969365426696, Blast_Score=166, Evalue=3e-41,
Organism=Saccharomyces cerevisiae, GI6324950, Length=453, Percent_Identity=29.5805739514349, Blast_Score=165, Evalue=4e-41,
Organism=Saccharomyces cerevisiae, GI6319478, Length=446, Percent_Identity=27.3542600896861, Blast_Score=146, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6321828, Length=478, Percent_Identity=24.4769874476987, Blast_Score=119, Evalue=4e-27,
Organism=Saccharomyces cerevisiae, GI6323757, Length=329, Percent_Identity=26.4437689969605, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI281362580, Length=466, Percent_Identity=31.7596566523605, Blast_Score=198, Evalue=3e-50,
Organism=Drosophila melanogaster, GI62472918, Length=466, Percent_Identity=31.7596566523605, Blast_Score=198, Evalue=3e-50,
Organism=Drosophila melanogaster, GI62472926, Length=466, Percent_Identity=31.7596566523605, Blast_Score=198, Evalue=3e-50,
Organism=Drosophila melanogaster, GI62472936, Length=466, Percent_Identity=31.7596566523605, Blast_Score=198, Evalue=3e-50,
Organism=Drosophila melanogaster, GI21356737, Length=466, Percent_Identity=31.7596566523605, Blast_Score=198, Evalue=3e-50,
Organism=Drosophila melanogaster, GI20129399, Length=450, Percent_Identity=30.4444444444444, Blast_Score=187, Evalue=4e-47,
Organism=Drosophila melanogaster, GI24668425, Length=513, Percent_Identity=29.8245614035088, Blast_Score=184, Evalue=4e-46,
Organism=Drosophila melanogaster, GI24668417, Length=513, Percent_Identity=29.8245614035088, Blast_Score=184, Evalue=4e-46,
Organism=Drosophila melanogaster, GI24668413, Length=513, Percent_Identity=29.8245614035088, Blast_Score=184, Evalue=4e-46,
Organism=Drosophila melanogaster, GI24585660, Length=465, Percent_Identity=29.0322580645161, Blast_Score=183, Evalue=7e-46,
Organism=Drosophila melanogaster, GI24650465, Length=453, Percent_Identity=29.8013245033113, Blast_Score=168, Evalue=3e-41,
Organism=Drosophila melanogaster, GI28571802, Length=464, Percent_Identity=28.6637931034483, Blast_Score=160, Evalue=9e-39,
Organism=Drosophila melanogaster, GI28571800, Length=464, Percent_Identity=28.6637931034483, Blast_Score=160, Evalue=9e-39,
Organism=Drosophila melanogaster, GI28571798, Length=464, Percent_Identity=28.6637931034483, Blast_Score=159, Evalue=1e-38,
Organism=Drosophila melanogaster, GI28571796, Length=464, Percent_Identity=28.6637931034483, Blast_Score=159, Evalue=1e-38,
Organism=Drosophila melanogaster, GI28571794, Length=464, Percent_Identity=28.6637931034483, Blast_Score=159, Evalue=1e-38,
Organism=Drosophila melanogaster, GI28571806, Length=464, Percent_Identity=28.6637931034483, Blast_Score=159, Evalue=1e-38,
Organism=Drosophila melanogaster, GI24666674, Length=451, Percent_Identity=27.7161862527716, Blast_Score=147, Evalue=5e-35,
Organism=Drosophila melanogaster, GI28574525, Length=495, Percent_Identity=25.2525252525253, Blast_Score=137, Evalue=6e-32,
Organism=Drosophila melanogaster, GI24638878, Length=459, Percent_Identity=26.3616557734205, Blast_Score=115, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24638876, Length=457, Percent_Identity=26.4770240700219, Blast_Score=115, Evalue=3e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR005933
- InterPro:   IPR002872 [H]

Pfam domain/function: PF00171 Aldedh; PF01619 Pro_dh [H]

EC number: =1.5.99.8; =1.5.1.12 [H]

Molecular weight: Translated: 150009; Mature: 150009

Theoretical pI: Translated: 8.00; Mature: 8.00

Prosite motif: PS00070 ALDEHYDE_DEHYDR_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDLLNHSGEYPISKEIMNIYKYWLIDEKEAMTKLVEKAHMSSVQKAQVRERAYGLVEKV
CCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RKNRLKKSGIDAFMIEYDLSSEEGVVLMCLAEALLRVPDKYTIDLLIKDKLTSAAWKNHV
HHHHHHHCCCCEEEEEEECCCCCCEEHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHCC
GMEKHLFVNAATWSLMLTGKILKDPHRSYRKVFQNFLKKTSEPVIRQAMKQAMKIVGKQY
CCCCEEEEEEEEEEEEEECHHHHCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
VLGETIEEALKVSEAKVARGYSYSYDMLGEAAMTMDDAEYYYSQYLHAIHELAKYATNTE
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCC
IKKNPGISIKLSALHPRYEVAKHQRVHTELYPKLLKLTQLAKDYNVGMNIDAEETERLQI
CCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
SLELVERLAHEPSLEGFNGIGIVVQAYQKRAPYVLDYLANLAKKTNRRFMIRLVKGAYWD
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCC
AEIKHAQEQGLAGYPVFTRKYHTDVSYQACVKQLFENHQYIYPQFATHNAQTVAVVFELA
HHHHHHHHCCCCCCCCCHHECCCCCCHHHHHHHHHHCCCEECCCCCCCCCCEEEEEEEEC
NGNRDFEFQCLHGMGDALYDNVVGKEGYEDIPCRIYAPVGGHKHLLAYLVRRLLENGANS
CCCCCEEEEEHHCCCHHHHHHHCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCH
SFVNRIVDENLPIEELIEDPVKKAIDHGCGQHPNIPYPKDIVSPRLNSQGHNTNDFAVLA
HHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCCCCCCCCCCHHHHHH
DMYKQIEKYTHKNTYKAKPIVSGIDLDKTITESVINPNTNEVIGSVINADAKIAKRALKN
HHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHH
AQSAFEEWSNTPATKRADILEKFADLLEQDTNKFIAIAMIEAGKTLANAIDEVREAVDFC
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHH
RYYAAQARKEFNGPIELPALSDHLKQIEFTGRGAMVCISPWNFPLAIFLGQITAVLAAGN
HHHHHHHHHHCCCCCCCCHHHHHHHHHEECCCCCEEEECCCCCHHHHHHHHHHHHHHCCC
TVVAKPAEQTPIIAYKAVKLLFKAGLPKNVLQFTPGDGATVGSALVKSPVCKGVIFTGST
EEEECCCCCCCHHHHHHHHHHHHCCCCCHHHEECCCCCCHHHHHHHHCHHHCCEEEECCC
EVAAIINQTLANKSSEIVPFIAETGGQNAMIVDSSSLPEQVTADVIRSAFDSAGQRCSAL
HHHHHHHHHHHCCCCCCEEEHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
RILCLQEDIADNYIKMIVGAMKELKIGDSKYIDTDVGPVIDKEAADNLNAYIEEKKSQFK
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHEE
LIYQSQPNQDTQKGTFVMPTAFEIDKISDLGREQFGPILHILRFKANQLDKLINDINATG
EEEECCCCCCCCCCEEEECCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
YGLTAGVHSRINEVMNYVKNNLKAGNIYVNRNIVGAVVGVQPFGGQGKSGTGPKAGGPYY
CCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCEEEEEEECCCCCCCCCCCCCCCCCCHHH
MHRLANEKLSGVGAVEEIYNPEKIAEYEKQTNKLIKDKYTITNIVAGEKAKKDKYTNLKA
HHHHHHHHHCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
ANGKTIGKKYVASVNTVDNAIEIASKEVEIWNHVNAEQRAATIEKFLELLEKERYLIASS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LVVESNISVEDAHIQIDKTIQQVAYYCLQAKKEFAHPQLLPGPTGEIDELSLKGRGVVVS
HEEECCCCEEHHHEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCEEEE
MCSSSDLLIRFVGQTAAALLAGNTVVAKPAYTGNLTAYNIVKLMLKAGIDSKVLHLVLSD
ECCCCCHHHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHHHCCCHHEEEEEECC
DEEITSALLFNSKVALVSFSGSVSAVKQVHQALVLRRGAIIPFVAESIAKNGKCTSLAIE
CHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEEEE
TASPLYLRRFVVEKTVSVDTTASGGNASLMSLEE
CCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEECC
>Mature Secondary Structure
MNDLLNHSGEYPISKEIMNIYKYWLIDEKEAMTKLVEKAHMSSVQKAQVRERAYGLVEKV
CCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RKNRLKKSGIDAFMIEYDLSSEEGVVLMCLAEALLRVPDKYTIDLLIKDKLTSAAWKNHV
HHHHHHHCCCCEEEEEEECCCCCCEEHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHCC
GMEKHLFVNAATWSLMLTGKILKDPHRSYRKVFQNFLKKTSEPVIRQAMKQAMKIVGKQY
CCCCEEEEEEEEEEEEEECHHHHCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
VLGETIEEALKVSEAKVARGYSYSYDMLGEAAMTMDDAEYYYSQYLHAIHELAKYATNTE
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCC
IKKNPGISIKLSALHPRYEVAKHQRVHTELYPKLLKLTQLAKDYNVGMNIDAEETERLQI
CCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
SLELVERLAHEPSLEGFNGIGIVVQAYQKRAPYVLDYLANLAKKTNRRFMIRLVKGAYWD
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCC
AEIKHAQEQGLAGYPVFTRKYHTDVSYQACVKQLFENHQYIYPQFATHNAQTVAVVFELA
HHHHHHHHCCCCCCCCCHHECCCCCCHHHHHHHHHHCCCEECCCCCCCCCCEEEEEEEEC
NGNRDFEFQCLHGMGDALYDNVVGKEGYEDIPCRIYAPVGGHKHLLAYLVRRLLENGANS
CCCCCEEEEEHHCCCHHHHHHHCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCH
SFVNRIVDENLPIEELIEDPVKKAIDHGCGQHPNIPYPKDIVSPRLNSQGHNTNDFAVLA
HHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCCCCCCCCCCHHHHHH
DMYKQIEKYTHKNTYKAKPIVSGIDLDKTITESVINPNTNEVIGSVINADAKIAKRALKN
HHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHH
AQSAFEEWSNTPATKRADILEKFADLLEQDTNKFIAIAMIEAGKTLANAIDEVREAVDFC
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHH
RYYAAQARKEFNGPIELPALSDHLKQIEFTGRGAMVCISPWNFPLAIFLGQITAVLAAGN
HHHHHHHHHHCCCCCCCCHHHHHHHHHEECCCCCEEEECCCCCHHHHHHHHHHHHHHCCC
TVVAKPAEQTPIIAYKAVKLLFKAGLPKNVLQFTPGDGATVGSALVKSPVCKGVIFTGST
EEEECCCCCCCHHHHHHHHHHHHCCCCCHHHEECCCCCCHHHHHHHHCHHHCCEEEECCC
EVAAIINQTLANKSSEIVPFIAETGGQNAMIVDSSSLPEQVTADVIRSAFDSAGQRCSAL
HHHHHHHHHHHCCCCCCEEEHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
RILCLQEDIADNYIKMIVGAMKELKIGDSKYIDTDVGPVIDKEAADNLNAYIEEKKSQFK
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHEE
LIYQSQPNQDTQKGTFVMPTAFEIDKISDLGREQFGPILHILRFKANQLDKLINDINATG
EEEECCCCCCCCCCEEEECCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
YGLTAGVHSRINEVMNYVKNNLKAGNIYVNRNIVGAVVGVQPFGGQGKSGTGPKAGGPYY
CCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCEEEEEEECCCCCCCCCCCCCCCCCCHHH
MHRLANEKLSGVGAVEEIYNPEKIAEYEKQTNKLIKDKYTITNIVAGEKAKKDKYTNLKA
HHHHHHHHHCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
ANGKTIGKKYVASVNTVDNAIEIASKEVEIWNHVNAEQRAATIEKFLELLEKERYLIASS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LVVESNISVEDAHIQIDKTIQQVAYYCLQAKKEFAHPQLLPGPTGEIDELSLKGRGVVVS
HEEECCCCEEHHHEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCEEEE
MCSSSDLLIRFVGQTAAALLAGNTVVAKPAYTGNLTAYNIVKLMLKAGIDSKVLHLVLSD
ECCCCCHHHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHHHCCCHHEEEEEECC
DEEITSALLFNSKVALVSFSGSVSAVKQVHQALVLRRGAIIPFVAESIAKNGKCTSLAIE
CHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEEEE
TASPLYLRRFVVEKTVSVDTTASGGNASLMSLEE
CCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7966312; 8905232; 9278503; 3325781; 12514740 [H]