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The map label for this gene is rpiA

Identifier: 89256123

GI number: 89256123

Start: 725411

End: 726085

Strand: Reverse

Name: rpiA

Synonym: FTL_0736

Alternate gene names: 89256123

Gene position: 726085-725411 (Counterclockwise)

Preceding gene: 89256124

Following gene: 89256120

Centisome position: 38.3

GC content: 34.52

Gene sequence:

>675_bases
ATGTTTTTTAATAAAAAAAATAACCAAGATGAGTTAAAAAAGCTTGCCGCAACTGAAGCTGCAAAAAGTATTACTACAGA
AATTACTTTAGGAGTCGGTACAGGAAGTACTGTTGGATTTTTAATCGAAGAACTTGTAAACTATAGAGACAAGATCAAAA
CTGTAGTATCAAGCTCGGAAGATTCAACCCGCAAACTCAAAGCGCTTGGTTTTGATGTAGTTGATCTTAATTATGCTGGT
GAGATTGATTTATACATTGATGGTGCAGATGAGTGCAACAATCACAAAGAACTCATCAAAGGTGGTGGTGCGGCTCTGAC
ACGTGAGAAAATTTGTGTGGCTGCTGCTAAGAAATTTATCTGTATCATTGATGAGTCAAAAAAAGTTAATACATTAGGTA
ATTTTCCTCTTCCTATAGAAGTTATCCCAATGGCAAGAAGCTATATAGCACGTCAAATAGTAAAGCTTGGCGGTCAACCA
GTATATAGAGAACAGACAATTACAGATAATGGTAATGTTATTCTGGATGTATATAATTTAAAAATTGATAACCCTCTAAA
ACTTGAAACAGAACTAAATCAAATCACAGGCGTTGTCACTAATGGCATCTTCGCTTTAAAACCTGCTGATACTGTGATTA
TGGCTACAAAAGATAGTAATATTGTTGTACTTTAA

Upstream 100 bases:

>100_bases
CCAATAATATGGCAATTTATTGCTACTTTAGCATGTATGATTATCTATATTGTCAAAGGAAGTATTTTTAGTAACATATT
TAGTAAGAGAAAGTTTTAAA

Downstream 100 bases:

>100_bases
TAAATCTGCTAAATAAGTGTCATTATTGAAATATTAAAAAATAATTATCACCAGATATTAACTCTTTGTTCTGGATCTAA
GTACATTCCATATCCAAATT

Product: ribose-5-phosphate isomerase A

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI

Number of amino acids: Translated: 224; Mature: 224

Protein sequence:

>224_residues
MFFNKKNNQDELKKLAATEAAKSITTEITLGVGTGSTVGFLIEELVNYRDKIKTVVSSSEDSTRKLKALGFDVVDLNYAG
EIDLYIDGADECNNHKELIKGGGAALTREKICVAAAKKFICIIDESKKVNTLGNFPLPIEVIPMARSYIARQIVKLGGQP
VYREQTITDNGNVILDVYNLKIDNPLKLETELNQITGVVTNGIFALKPADTVIMATKDSNIVVL

Sequences:

>Translated_224_residues
MFFNKKNNQDELKKLAATEAAKSITTEITLGVGTGSTVGFLIEELVNYRDKIKTVVSSSEDSTRKLKALGFDVVDLNYAG
EIDLYIDGADECNNHKELIKGGGAALTREKICVAAAKKFICIIDESKKVNTLGNFPLPIEVIPMARSYIARQIVKLGGQP
VYREQTITDNGNVILDVYNLKIDNPLKLETELNQITGVVTNGIFALKPADTVIMATKDSNIVVL
>Mature_224_residues
MFFNKKNNQDELKKLAATEAAKSITTEITLGVGTGSTVGFLIEELVNYRDKIKTVVSSSEDSTRKLKALGFDVVDLNYAG
EIDLYIDGADECNNHKELIKGGGAALTREKICVAAAKKFICIIDESKKVNTLGNFPLPIEVIPMARSYIARQIVKLGGQP
VYREQTITDNGNVILDVYNLKIDNPLKLETELNQITGVVTNGIFALKPADTVIMATKDSNIVVL

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family

Homologues:

Organism=Homo sapiens, GI94536842, Length=226, Percent_Identity=34.5132743362832, Blast_Score=102, Evalue=2e-22,
Organism=Escherichia coli, GI1789280, Length=211, Percent_Identity=54.0284360189574, Blast_Score=235, Evalue=1e-63,
Organism=Caenorhabditis elegans, GI17551758, Length=229, Percent_Identity=34.4978165938865, Blast_Score=100, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6324669, Length=196, Percent_Identity=31.6326530612245, Blast_Score=76, Evalue=5e-15,
Organism=Drosophila melanogaster, GI281364072, Length=193, Percent_Identity=34.1968911917098, Blast_Score=83, Evalue=2e-16,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): RPIA_FRAT1 (Q14H27)

Other databases:

- EMBL:   AM286280
- RefSeq:   YP_667299.1
- ProteinModelPortal:   Q14H27
- SMR:   Q14H27
- STRING:   Q14H27
- GeneID:   4200772
- GenomeReviews:   AM286280_GR
- KEGG:   ftf:FTF1208
- eggNOG:   COG0120
- HOGENOM:   HBG515603
- OMA:   DKSIVGV
- PhylomeDB:   Q14H27
- ProtClustDB:   PRK00702
- BioCyc:   FTUL393115:FTF1208-MONOMER
- HAMAP:   MF_00170
- InterPro:   IPR004788
- InterPro:   IPR020672
- PANTHER:   PTHR11934
- TIGRFAMs:   TIGR00021

Pfam domain/function: PF06026 Rib_5-P_isom_A

EC number: =5.3.1.6

Molecular weight: Translated: 24467; Mature: 24467

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFFNKKNNQDELKKLAATEAAKSITTEITLGVGTGSTVGFLIEELVNYRDKIKTVVSSSE
CCCCCCCCHHHHHHHHHHHHHHHHEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCC
DSTRKLKALGFDVVDLNYAGEIDLYIDGADECNNHKELIKGGGAALTREKICVAAAKKFI
CHHHHHHHHCCEEEEECCCCEEEEEECCCHHCCCHHHHHHCCCCHHHHHHHHHHHHCEEE
CIIDESKKVNTLGNFPLPIEVIPMARSYIARQIVKLGGQPVYREQTITDNGNVILDVYNL
EEEECCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHCCCCCCCCEEECCCCCEEEEEEEE
KIDNPLKLETELNQITGVVTNGIFALKPADTVIMATKDSNIVVL
EECCCEEEHHHHHHHHHHHHCCEEEECCCCEEEEEECCCCEEEC
>Mature Secondary Structure
MFFNKKNNQDELKKLAATEAAKSITTEITLGVGTGSTVGFLIEELVNYRDKIKTVVSSSE
CCCCCCCCHHHHHHHHHHHHHHHHEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCC
DSTRKLKALGFDVVDLNYAGEIDLYIDGADECNNHKELIKGGGAALTREKICVAAAKKFI
CHHHHHHHHCCEEEEECCCCEEEEEECCCHHCCCHHHHHHCCCCHHHHHHHHHHHHCEEE
CIIDESKKVNTLGNFPLPIEVIPMARSYIARQIVKLGGQPVYREQTITDNGNVILDVYNL
EEEECCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHCCCCCCCCEEECCCCCEEEEEEEE
KIDNPLKLETELNQITGVVTNGIFALKPADTVIMATKDSNIVVL
EECCCEEEHHHHHHHHHHHHCCEEEECCCCEEEEEECCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA