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The map label for this gene is fabZ [H]

Identifier: 89255945

GI number: 89255945

Start: 521733

End: 522224

Strand: Direct

Name: fabZ [H]

Synonym: FTL_0538

Alternate gene names: 89255945

Gene position: 521733-522224 (Clockwise)

Preceding gene: 89255944

Following gene: 89255946

Centisome position: 27.52

GC content: 37.6

Gene sequence:

>492_bases
ATGAGCCAGTTTAATCAAAATAATAAACAGATAGATGTAATGGGGATTAGAAAAATCTTACCTCACAGGTATCCTTTTGC
ACTTTTGGATAAGATCGTTGATTGGAGTGTTGAAGATAGAACGATTGTTGCACAAAAAAATGTCACTATAAATGAAGATT
TTTTCAATGGACATTTTCCTGATTTCCCAGTTATGCCTGGTGTACTGATAGTTGAAGCGATGGCTCAAGCAACGGCAATA
CTTGGTGAACTAATGGCAGAGACATTGTTCGCACATGTTGTTGAGAAAGCTGGTGGTGGTAGAAGAACATTCATGCTAGC
TGGTATTGATAAGGTAAGGGTCAAAAGACCTGTAGTACCAGGAGATGTGTTAGTAATTGAGTCGCGTATGGTAAAACAAA
AAAATATTATCTGTACAGCAGAGTCAGTCGCAAAGGTTGATGGACAAATTGTTTGTTCAGCTGAATTAATGGCAGCATAT
AAGGACTACTAA

Upstream 100 bases:

>100_bases
TTCAATGGGGTAGGTTCGTAGCTAAATTAGCTAAGATTGATACTCTAATTACAAAAGTAAAGCAACTAGAAGAAAAAATT
AAATAAGTAAGGATTGTTTA

Downstream 100 bases:

>100_bases
TCGTGATACATAGTTTGGCAGTAGTACATGAGAGCGCCAAAATAGCCGATAGTGCTATAATAGGGCCATTCTGTGTTATT
GGGAAGAATGTTGTTATTGG

Product: (3R)-hydroxymyristoyl-ACP dehydratase

Products: trans-Delta2-enoyl-acyl-ACP; H2O [C]

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase [H]

Number of amino acids: Translated: 163; Mature: 162

Protein sequence:

>163_residues
MSQFNQNNKQIDVMGIRKILPHRYPFALLDKIVDWSVEDRTIVAQKNVTINEDFFNGHFPDFPVMPGVLIVEAMAQATAI
LGELMAETLFAHVVEKAGGGRRTFMLAGIDKVRVKRPVVPGDVLVIESRMVKQKNIICTAESVAKVDGQIVCSAELMAAY
KDY

Sequences:

>Translated_163_residues
MSQFNQNNKQIDVMGIRKILPHRYPFALLDKIVDWSVEDRTIVAQKNVTINEDFFNGHFPDFPVMPGVLIVEAMAQATAI
LGELMAETLFAHVVEKAGGGRRTFMLAGIDKVRVKRPVVPGDVLVIESRMVKQKNIICTAESVAKVDGQIVCSAELMAAY
KDY
>Mature_162_residues
SQFNQNNKQIDVMGIRKILPHRYPFALLDKIVDWSVEDRTIVAQKNVTINEDFFNGHFPDFPVMPGVLIVEAMAQATAIL
GELMAETLFAHVVEKAGGGRRTFMLAGIDKVRVKRPVVPGDVLVIESRMVKQKNIICTAESVAKVDGQIVCSAELMAAYK
DY

Specific function: Involved in saturated fatty acids biosynthesis [H]

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786377, Length=155, Percent_Identity=43.8709677419355, Blast_Score=130, Evalue=5e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013114
- InterPro:   IPR010084 [H]

Pfam domain/function: PF07977 FabA [H]

EC number: 4.2.1.- [C]

Molecular weight: Translated: 18151; Mature: 18019

Theoretical pI: Translated: 7.51; Mature: 7.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQFNQNNKQIDVMGIRKILPHRYPFALLDKIVDWSVEDRTIVAQKNVTINEDFFNGHFP
CCCCCCCCCEEEEEEHHHHCCCCCCHHHHHHHHCCCCCCCEEEEECCCEECCCCCCCCCC
DFPVMPGVLIVEAMAQATAILGELMAETLFAHVVEKAGGGRRTFMLAGIDKVRVKRPVVP
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHCCCCCC
GDVLVIESRMVKQKNIICTAESVAKVDGQIVCSAELMAAYKDY
CCEEEEHHHHHHHCCEEEEHHHHHHCCCEEEEHHHHHHHHCCC
>Mature Secondary Structure 
SQFNQNNKQIDVMGIRKILPHRYPFALLDKIVDWSVEDRTIVAQKNVTINEDFFNGHFP
CCCCCCCCEEEEEEHHHHCCCCCCHHHHHHHHCCCCCCCEEEEECCCEECCCCCCCCCC
DFPVMPGVLIVEAMAQATAILGELMAETLFAHVVEKAGGGRRTFMLAGIDKVRVKRPVVP
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHCCCCCC
GDVLVIESRMVKQKNIICTAESVAKVDGQIVCSAELMAAYKDY
CCEEEEHHHHHHHCCEEEEHHHHHHCCCEEEEHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: D-3-hydroxy-acyl-ACP [C]

Specific reaction: D-3-hydroxy-acyl-ACP = trans-Delta2-enoyl-acyl-ACP + H2O [C]

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA