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The map label for this gene is asd [H]

Identifier: 89255904

GI number: 89255904

Start: 479944

End: 480993

Strand: Reverse

Name: asd [H]

Synonym: FTL_0494

Alternate gene names: 89255904

Gene position: 480993-479944 (Counterclockwise)

Preceding gene: 89255913

Following gene: 89255893

Centisome position: 25.37

GC content: 34.38

Gene sequence:

>1050_bases
ATGTCTCGTATGATCGAATCAAAAGATTTTGATTGTATTTTGCCAACGTTTTTTTCGACATCTCAGGTAAGGCAGCTGCC
AACAGGTTTTATGCAACAATATGGAGCGTTACAAGATGCCTATAGTATCGACCAACTAAGTAGTATGGATATACTTCTAA
GTTGCCAAGGTGGTGAATATACCAAAGAAATACACCACAAATTAAGAGAAGCCGGCTGGCAAGGTTTCTGGATAGACGCT
GCATCGACACTACGCTTAGACAAAGATAATACTCTAGTTCTAGACCCTCTAAATCACGATCAAATAATTAATGCTATTGA
TAATGGTAAAAAAGATTTTATCGGTAGTAATTGTACTGTTAGTCTAATGTCACTAGCTATAGCTGGACTACTCAAAGAAG
ATCTTGTTGAATGGGTTAACTCTAGTACTTATCAAGCAATTTCAGGAGCGGGTGCCGCAGCAATGCAAGAACTACTTCAA
CAAACAAGCCTTTTAAGCAAAATTGATAATAGAGATGAAGATATTCTAATTAGAGAAAAAATTCTCAGAGAATTATCAAA
AGACTCATCAAAAATCCCTCAACAAAAAACTGTACAAACTTTGGCTTATAATCTATTACCTTGGATAGATGTTGGTATGC
CTAGTGGACAAACAAAAGAAGAGTACAAAGCAGCTACAGAACTTAATAAAATTCTAGATACTAAAAAAACAATCCCTGTC
GATGGTATATGTGTCAGAGTACCAAGTCTAAGATCACACTCTCAAGCATTAACAGTCAAACTTAGACAGAAATTAACAAT
TGAAGAAATTAAGCAAAAAATATCTCAAGGTAATGAATGGGTTAAAGTAATAGATAATAATAAAGAAGATACTTTAAAAT
ACCTAACACCTCAAGCTACTTCAGGAACTCTTGATATTGCTATAGGTCGTATCAAATCATCGTTATTAGCTGATGATATA
TTTCATTGTTTCACAGTAGGTGATCAGCTATTACGGGGAGCTGCTGAGCCCCTTAGAAGAGTTTTAAATATTATTAAAAA
TAAAATCTGA

Upstream 100 bases:

>100_bases
AACATTTTTTATTTTTTCTGCAGTAGCAAGGCTACTCCCACCAAACTTATGCCTTAAAGTTGGTTTTATTGGTTGGCGCA
GAATAGTCGGCTCAGTTTTA

Downstream 100 bases:

>100_bases
GATAAAAAATCTTAGAAAGTTTAAAAGATAATTATCAATACTTTTAGGCTATTCCCAAACATAGCCTTTTGGCAAATCAC
AAGATACGCCTTTTTGACTT

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 349; Mature: 348

Protein sequence:

>349_residues
MSRMIESKDFDCILPTFFSTSQVRQLPTGFMQQYGALQDAYSIDQLSSMDILLSCQGGEYTKEIHHKLREAGWQGFWIDA
ASTLRLDKDNTLVLDPLNHDQIINAIDNGKKDFIGSNCTVSLMSLAIAGLLKEDLVEWVNSSTYQAISGAGAAAMQELLQ
QTSLLSKIDNRDEDILIREKILRELSKDSSKIPQQKTVQTLAYNLLPWIDVGMPSGQTKEEYKAATELNKILDTKKTIPV
DGICVRVPSLRSHSQALTVKLRQKLTIEEIKQKISQGNEWVKVIDNNKEDTLKYLTPQATSGTLDIAIGRIKSSLLADDI
FHCFTVGDQLLRGAAEPLRRVLNIIKNKI

Sequences:

>Translated_349_residues
MSRMIESKDFDCILPTFFSTSQVRQLPTGFMQQYGALQDAYSIDQLSSMDILLSCQGGEYTKEIHHKLREAGWQGFWIDA
ASTLRLDKDNTLVLDPLNHDQIINAIDNGKKDFIGSNCTVSLMSLAIAGLLKEDLVEWVNSSTYQAISGAGAAAMQELLQ
QTSLLSKIDNRDEDILIREKILRELSKDSSKIPQQKTVQTLAYNLLPWIDVGMPSGQTKEEYKAATELNKILDTKKTIPV
DGICVRVPSLRSHSQALTVKLRQKLTIEEIKQKISQGNEWVKVIDNNKEDTLKYLTPQATSGTLDIAIGRIKSSLLADDI
FHCFTVGDQLLRGAAEPLRRVLNIIKNKI
>Mature_348_residues
SRMIESKDFDCILPTFFSTSQVRQLPTGFMQQYGALQDAYSIDQLSSMDILLSCQGGEYTKEIHHKLREAGWQGFWIDAA
STLRLDKDNTLVLDPLNHDQIINAIDNGKKDFIGSNCTVSLMSLAIAGLLKEDLVEWVNSSTYQAISGAGAAAMQELLQQ
TSLLSKIDNRDEDILIREKILRELSKDSSKIPQQKTVQTLAYNLLPWIDVGMPSGQTKEEYKAATELNKILDTKKTIPVD
GICVRVPSLRSHSQALTVKLRQKLTIEEIKQKISQGNEWVKVIDNNKEDTLKYLTPQATSGTLDIAIGRIKSSLLADDIF
HCFTVGDQLLRGAAEPLRRVLNIIKNKI

Specific function: Second step in the common biosynthetic pathway leading from Asp to the cell wall precursor meso-diaminopimelate, to Lys, to Met, to Ile and to Thr. [C]

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1789841, Length=347, Percent_Identity=47.2622478386167, Blast_Score=345, Evalue=3e-96,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR011534
- InterPro:   IPR012080
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 39039; Mature: 38908

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS01103 ASD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRMIESKDFDCILPTFFSTSQVRQLPTGFMQQYGALQDAYSIDQLSSMDILLSCQGGEY
CCCCCCCCCCCEECHHHHCHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCH
TKEIHHKLREAGWQGFWIDAASTLRLDKDNTLVLDPLNHDQIINAIDNGKKDFIGSNCTV
HHHHHHHHHHCCCCEEEEECCCEEEECCCCEEEECCCCHHHHHHHHHCCCHHHCCCCHHH
SLMSLAIAGLLKEDLVEWVNSSTYQAISGAGAAAMQELLQQTSLLSKIDNRDEDILIREK
HHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
ILRELSKDSSKIPQQKTVQTLAYNLLPWIDVGMPSGQTKEEYKAATELNKILDTKKTIPV
HHHHHHCCHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCC
DGICVRVPSLRSHSQALTVKLRQKLTIEEIKQKISQGNEWVKVIDNNKEDTLKYLTPQAT
CCEEEECCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCEEEEECCCCHHHHHHCCCCCC
SGTLDIAIGRIKSSLLADDIFHCFTVGDQLLRGAAEPLRRVLNIIKNKI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SRMIESKDFDCILPTFFSTSQVRQLPTGFMQQYGALQDAYSIDQLSSMDILLSCQGGEY
CCCCCCCCCCEECHHHHCHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCH
TKEIHHKLREAGWQGFWIDAASTLRLDKDNTLVLDPLNHDQIINAIDNGKKDFIGSNCTV
HHHHHHHHHHCCCCEEEEECCCEEEECCCCEEEECCCCHHHHHHHHHCCCHHHCCCCHHH
SLMSLAIAGLLKEDLVEWVNSSTYQAISGAGAAAMQELLQQTSLLSKIDNRDEDILIREK
HHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
ILRELSKDSSKIPQQKTVQTLAYNLLPWIDVGMPSGQTKEEYKAATELNKILDTKKTIPV
HHHHHHCCHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCC
DGICVRVPSLRSHSQALTVKLRQKLTIEEIKQKISQGNEWVKVIDNNKEDTLKYLTPQAT
CCEEEECCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCEEEEECCCCHHHHHHCCCCCC
SGTLDIAIGRIKSSLLADDIFHCFTVGDQLLRGAAEPLRRVLNIIKNKI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]