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The map label for this gene is msrB2 [H]

Identifier: 89054634

GI number: 89054634

Start: 2150761

End: 2151210

Strand: Reverse

Name: msrB2 [H]

Synonym: Jann_2143

Alternate gene names: 89054634

Gene position: 2151210-2150761 (Counterclockwise)

Preceding gene: 89054635

Following gene: 89054633

Centisome position: 49.82

GC content: 60.89

Gene sequence:

>450_bases
ATGACCACTTACACCAAAGACCCCGACGTGATCGCCACCCTGACGCCCGAGCAGTTCCGCGTCACACAGCAAGACGCGAC
GGAGCGTCCGGGCACGGGAGAGCTGTTGTATAACAAAGAGCCGGGGATTTACGTCGATATCGTCTCGGGCGAGCCGTTGT
TTGCCTCAGCCGACAAGTACGAATCCGGCTGCGGCTGGCCGAGCTTCACCAAAGCCATCGAGCCTGCCCATGTGAACGAG
TTGCGCGACAGCTCGCTTGGCATGGTCAGGACCGAAGTCCGCTCCACCCACGGTGACAGCCATCTGGGCCACGTCTTTCC
CGATGGCCCGGCCGACCGTGGCGGTCTGCGGTATTGCATCAACTCCGCCTCACTGCGGTTCGTGCATCGCGACGACATGG
AAAACGAAGGCTATGGGGCGTATGTTGATCAAGTGGAGGACGTGGCATGA

Upstream 100 bases:

>100_bases
CCGGCCCGGGGCGTTTTCGTTTGACGCCCCCTGTCGAACACGCCCTTGGACAAATCCCCCGCCACCCCCATATCTTGTGA
ACCAAGATAGCGGAGGCTCC

Downstream 100 bases:

>100_bases
CGGAACGTGCAGTTTTGGCGGGCGGTTGCTTTTGGGGCATGCAGGATCTGATCCGCAAAATGCCCGGAGTTGAGGCCACG
CGCGTGGGTTACACGGGCGG

Product: methionine sulfoxide reductase B

Products: NA

Alternate protein names: Peptide-methionine (R)-S-oxide reductase 2 [H]

Number of amino acids: Translated: 149; Mature: 148

Protein sequence:

>149_residues
MTTYTKDPDVIATLTPEQFRVTQQDATERPGTGELLYNKEPGIYVDIVSGEPLFASADKYESGCGWPSFTKAIEPAHVNE
LRDSSLGMVRTEVRSTHGDSHLGHVFPDGPADRGGLRYCINSASLRFVHRDDMENEGYGAYVDQVEDVA

Sequences:

>Translated_149_residues
MTTYTKDPDVIATLTPEQFRVTQQDATERPGTGELLYNKEPGIYVDIVSGEPLFASADKYESGCGWPSFTKAIEPAHVNE
LRDSSLGMVRTEVRSTHGDSHLGHVFPDGPADRGGLRYCINSASLRFVHRDDMENEGYGAYVDQVEDVA
>Mature_148_residues
TTYTKDPDVIATLTPEQFRVTQQDATERPGTGELLYNKEPGIYVDIVSGEPLFASADKYESGCGWPSFTKAIEPAHVNEL
RDSSLGMVRTEVRSTHGDSHLGHVFPDGPADRGGLRYCINSASLRFVHRDDMENEGYGAYVDQVEDVA

Specific function: Unknown

COG id: COG0229

COG function: function code O; Conserved domain frequently associated with peptide methionine sulfoxide reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrB Met sulfoxide reductase family [H]

Homologues:

Organism=Homo sapiens, GI117606353, Length=125, Percent_Identity=49.6, Blast_Score=113, Evalue=7e-26,
Organism=Homo sapiens, GI301336164, Length=118, Percent_Identity=47.4576271186441, Blast_Score=108, Evalue=2e-24,
Organism=Homo sapiens, GI301336162, Length=118, Percent_Identity=47.4576271186441, Blast_Score=108, Evalue=2e-24,
Organism=Homo sapiens, GI73089054, Length=118, Percent_Identity=47.4576271186441, Blast_Score=108, Evalue=2e-24,
Organism=Homo sapiens, GI37620216, Length=118, Percent_Identity=47.4576271186441, Blast_Score=107, Evalue=3e-24,
Organism=Escherichia coli, GI1788077, Length=120, Percent_Identity=50, Blast_Score=124, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI17553450, Length=127, Percent_Identity=42.5196850393701, Blast_Score=105, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI115532676, Length=128, Percent_Identity=42.1875, Blast_Score=105, Evalue=7e-24,
Organism=Saccharomyces cerevisiae, GI6319816, Length=120, Percent_Identity=39.1666666666667, Blast_Score=89, Evalue=4e-19,
Organism=Drosophila melanogaster, GI221378664, Length=118, Percent_Identity=52.5423728813559, Blast_Score=116, Evalue=4e-27,
Organism=Drosophila melanogaster, GI221378662, Length=125, Percent_Identity=50.4, Blast_Score=115, Evalue=1e-26,
Organism=Drosophila melanogaster, GI45553335, Length=121, Percent_Identity=50.4132231404959, Blast_Score=113, Evalue=4e-26,
Organism=Drosophila melanogaster, GI21356369, Length=121, Percent_Identity=50.4132231404959, Blast_Score=113, Evalue=4e-26,
Organism=Drosophila melanogaster, GI24645799, Length=121, Percent_Identity=50.4132231404959, Blast_Score=113, Evalue=5e-26,
Organism=Drosophila melanogaster, GI24645804, Length=132, Percent_Identity=46.2121212121212, Blast_Score=108, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24645801, Length=132, Percent_Identity=46.2121212121212, Blast_Score=108, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002579
- InterPro:   IPR011057 [H]

Pfam domain/function: PF01641 SelR [H]

EC number: =1.8.4.12 [H]

Molecular weight: Translated: 16441; Mature: 16310

Theoretical pI: Translated: 4.42; Mature: 4.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTYTKDPDVIATLTPEQFRVTQQDATERPGTGELLYNKEPGIYVDIVSGEPLFASADKY
CCCCCCCCCEEEEECHHHEEEECHHCCCCCCCCCEEEECCCCEEEEEECCCCEEECCCCC
ESGCGWPSFTKAIEPAHVNELRDSSLGMVRTEVRSTHGDSHLGHVFPDGPADRGGLRYCI
CCCCCCCHHHHHCCCHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEE
NSASLRFVHRDDMENEGYGAYVDQVEDVA
CCCEEEEEECCCCCCCCCCHHHHHHHCCC
>Mature Secondary Structure 
TTYTKDPDVIATLTPEQFRVTQQDATERPGTGELLYNKEPGIYVDIVSGEPLFASADKY
CCCCCCCCEEEEECHHHEEEECHHCCCCCCCCCEEEECCCCEEEEEECCCCEEECCCCC
ESGCGWPSFTKAIEPAHVNELRDSSLGMVRTEVRSTHGDSHLGHVFPDGPADRGGLRYCI
CCCCCCCHHHHHCCCHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEE
NSASLRFVHRDDMENEGYGAYVDQVEDVA
CCCEEEEEECCCCCCCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481432 [H]