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The map label for this gene is yciR [C]

Identifier: 89054522

GI number: 89054522

Start: 2036403

End: 2038112

Strand: Reverse

Name: yciR [C]

Synonym: Jann_2031

Alternate gene names: 89054522

Gene position: 2038112-2036403 (Counterclockwise)

Preceding gene: 89054523

Following gene: 89054521

Centisome position: 47.2

GC content: 53.1

Gene sequence:

>1710_bases
TTGGGACATCATTCCAAGAAAAATCAGTCGACTGGTCCGGTGTCCATCGACGTCCCGATGGTCGGTGATCCGGCGCATGT
TCTCCGCGGATTGCTCACAGCCCAAGTCGGGATCGTGTGCCTGTCAGACTCGGGTGACATCTCCTTCGTGAGCAGAGAGT
TTCTTGCAGCATTTGGCCAGCAATCGCTTGATCCCGGAACTGTCATTGGGCAGCCCTATCAAGCTGTCTTCGACGCAGCG
TTGGAACCTTATGACATATCTGAAACACGCAAGACTGCTCTGGCGACCGGATTGGCCGTATCAAAGACACAACCAGATGT
CGCCTGGTCCTCAAACCCTGCGGGCGGCAGCATCGGTATCCTGACCGGCTCTGCGACCGAGCTGTCGCAATCTGCGCCCA
TGTTTGAACCAGATGAACTGACAGGTTTAGGGAACCGAAAGTATCTCAAGGCTTGTTTTGAGGCTATCGCCCAAGAAGAT
AGTGGCGCGATCGCGCTCTTTCTCGACCTCGATCACTTCAAGCAGGTCAATGATACGCTCGGTCATGCCATTGGAGACAA
ACTGCTTTGCAAAGTTGCGGACCGGCTCCGAAAATCCGTGCGGGAAGGCGACATAGTTGTGCGGATCGGCGGGGATGAGT
TCGCGATTTTGCTGATTAATTGGGATCAGTCCGCGGCCGAAGACGTAGCGGCACGCATTATCAAGGTGATCGGCAGGCCA
TTTCTAATTGAAGGCCATCAAGTCACAATAGGCGTAAGCATCGGAATGGCCGTCCGGCTACCGAACGAGCGGGAATCCGA
GAAGTTGCTGCAACGGGCAGACGTCGCCTTGTATGAAAGCAAGCGTCTTGGCCGCAATCGCTTTCACTGGTTCAAAGATG
CGATGTTGATCGAGTTGCAACAGCGGCGCGACACAGAGATCGATCTTCGTAAGGCCGTCTTATTGGGCCAATTTGGTGTT
GTTTTCCAACCGCAGATGAACTTTCAAGACCAAGACATCACTGGCTTTGAGGCCCTTGTCCGGTGGAACCACCCGCTTCG
CGGAGTGATCGCGCCGATTGAATTTATTGAAATTGCGGAAGAAACTGGCCTAATTGTGGAAATTGGGACCTGGGTGCTGG
CCGAGGCATGTCAGGCTGCCGCCGGATGGCCAGAGGACATCGCGGTCGCCGTCAATATTTCGCCCGTACAATTTGAAGAT
GAGGGCTTTATGGTGTCCGTTCAGACGGCTCTACAGAAATCGAAACTTCAGCCGCATCGATTGGAACTGGAGATCACCGA
AGCAACGCTCCTCTCAAACGAAGAAGCTGTTTTGGCGCGTATGAATGAACTCCAAGGGCTTGGCATCAAGATATCTCTAG
ATGACTTTGGCATCGGCTACTCGTCTTTGAATTACCTGCGCAAGTACCCATTCGACAAGGTGAAAATCGACCAATCCTTT
GTGCGCGAACCCTTTGCGGACGAGAGTTCCCATCAGATTGTGGAGGCCGTTGCACATCTTGGCTCAGCTCTAGGCATGAC
GGTACTGGCCGAAGGTGTAGAAACGCACGAGCAAATGGAACGCATCCGATCAAAGGGTTGCGCATCTATTCAAGGCTATC
TGGTTGGTCGTCCGATCCCGCTCGACGACATTACATCTTTTCTCACGTCTTTACCGAACGAGATTGGCGGGAGAAAACCT
TTGCCCGCAATACAAGGAGACACGACATGA

Upstream 100 bases:

>100_bases
TATCATTTTAGACGCATCGGACCTGAGCCAGAGCACGTTTCAACCAAACATTCATATCTCGCGCTGTAACAAAACACCCA
TCACAGGGAGGAAAGACGCG

Downstream 100 bases:

>100_bases
CAGACGGGGACCTTCTTCGCGTTGTGTATTTTAGCTTTCAGAATACCGACATCGATCATGACGAGATAGATCAGCATGTG
AACGAGATCCTGAAAAAATC

Product: diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 569; Mature: 568

Protein sequence:

>569_residues
MGHHSKKNQSTGPVSIDVPMVGDPAHVLRGLLTAQVGIVCLSDSGDISFVSREFLAAFGQQSLDPGTVIGQPYQAVFDAA
LEPYDISETRKTALATGLAVSKTQPDVAWSSNPAGGSIGILTGSATELSQSAPMFEPDELTGLGNRKYLKACFEAIAQED
SGAIALFLDLDHFKQVNDTLGHAIGDKLLCKVADRLRKSVREGDIVVRIGGDEFAILLINWDQSAAEDVAARIIKVIGRP
FLIEGHQVTIGVSIGMAVRLPNERESEKLLQRADVALYESKRLGRNRFHWFKDAMLIELQQRRDTEIDLRKAVLLGQFGV
VFQPQMNFQDQDITGFEALVRWNHPLRGVIAPIEFIEIAEETGLIVEIGTWVLAEACQAAAGWPEDIAVAVNISPVQFED
EGFMVSVQTALQKSKLQPHRLELEITEATLLSNEEAVLARMNELQGLGIKISLDDFGIGYSSLNYLRKYPFDKVKIDQSF
VREPFADESSHQIVEAVAHLGSALGMTVLAEGVETHEQMERIRSKGCASIQGYLVGRPIPLDDITSFLTSLPNEIGGRKP
LPAIQGDTT

Sequences:

>Translated_569_residues
MGHHSKKNQSTGPVSIDVPMVGDPAHVLRGLLTAQVGIVCLSDSGDISFVSREFLAAFGQQSLDPGTVIGQPYQAVFDAA
LEPYDISETRKTALATGLAVSKTQPDVAWSSNPAGGSIGILTGSATELSQSAPMFEPDELTGLGNRKYLKACFEAIAQED
SGAIALFLDLDHFKQVNDTLGHAIGDKLLCKVADRLRKSVREGDIVVRIGGDEFAILLINWDQSAAEDVAARIIKVIGRP
FLIEGHQVTIGVSIGMAVRLPNERESEKLLQRADVALYESKRLGRNRFHWFKDAMLIELQQRRDTEIDLRKAVLLGQFGV
VFQPQMNFQDQDITGFEALVRWNHPLRGVIAPIEFIEIAEETGLIVEIGTWVLAEACQAAAGWPEDIAVAVNISPVQFED
EGFMVSVQTALQKSKLQPHRLELEITEATLLSNEEAVLARMNELQGLGIKISLDDFGIGYSSLNYLRKYPFDKVKIDQSF
VREPFADESSHQIVEAVAHLGSALGMTVLAEGVETHEQMERIRSKGCASIQGYLVGRPIPLDDITSFLTSLPNEIGGRKP
LPAIQGDTT
>Mature_568_residues
GHHSKKNQSTGPVSIDVPMVGDPAHVLRGLLTAQVGIVCLSDSGDISFVSREFLAAFGQQSLDPGTVIGQPYQAVFDAAL
EPYDISETRKTALATGLAVSKTQPDVAWSSNPAGGSIGILTGSATELSQSAPMFEPDELTGLGNRKYLKACFEAIAQEDS
GAIALFLDLDHFKQVNDTLGHAIGDKLLCKVADRLRKSVREGDIVVRIGGDEFAILLINWDQSAAEDVAARIIKVIGRPF
LIEGHQVTIGVSIGMAVRLPNERESEKLLQRADVALYESKRLGRNRFHWFKDAMLIELQQRRDTEIDLRKAVLLGQFGVV
FQPQMNFQDQDITGFEALVRWNHPLRGVIAPIEFIEIAEETGLIVEIGTWVLAEACQAAAGWPEDIAVAVNISPVQFEDE
GFMVSVQTALQKSKLQPHRLELEITEATLLSNEEAVLARMNELQGLGIKISLDDFGIGYSSLNYLRKYPFDKVKIDQSFV
REPFADESSHQIVEAVAHLGSALGMTVLAEGVETHEQMERIRSKGCASIQGYLVGRPIPLDDITSFLTSLPNEIGGRKPL
PAIQGDTT

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=408, Percent_Identity=35.5392156862745, Blast_Score=261, Evalue=1e-70,
Organism=Escherichia coli, GI87081921, Length=423, Percent_Identity=33.096926713948, Blast_Score=249, Evalue=5e-67,
Organism=Escherichia coli, GI226510982, Length=411, Percent_Identity=27.007299270073, Blast_Score=163, Evalue=3e-41,
Organism=Escherichia coli, GI1788502, Length=257, Percent_Identity=33.4630350194552, Blast_Score=148, Evalue=1e-36,
Organism=Escherichia coli, GI87081980, Length=249, Percent_Identity=34.9397590361446, Blast_Score=139, Evalue=6e-34,
Organism=Escherichia coli, GI87081845, Length=251, Percent_Identity=33.0677290836653, Blast_Score=138, Evalue=9e-34,
Organism=Escherichia coli, GI1787055, Length=260, Percent_Identity=30.7692307692308, Blast_Score=135, Evalue=8e-33,
Organism=Escherichia coli, GI1786507, Length=234, Percent_Identity=34.1880341880342, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1790496, Length=247, Percent_Identity=29.1497975708502, Blast_Score=128, Evalue=8e-31,
Organism=Escherichia coli, GI1788849, Length=225, Percent_Identity=35.5555555555556, Blast_Score=121, Evalue=1e-28,
Organism=Escherichia coli, GI87082096, Length=199, Percent_Identity=29.6482412060301, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1788381, Length=463, Percent_Identity=25.0539956803456, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1786584, Length=206, Percent_Identity=32.0388349514563, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI87081743, Length=245, Percent_Identity=27.7551020408163, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1787262, Length=157, Percent_Identity=35.6687898089172, Blast_Score=96, Evalue=9e-21,
Organism=Escherichia coli, GI145693134, Length=164, Percent_Identity=37.1951219512195, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1788956, Length=149, Percent_Identity=35.5704697986577, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI87081881, Length=163, Percent_Identity=39.2638036809816, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI1787816, Length=154, Percent_Identity=36.3636363636364, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI87081977, Length=150, Percent_Identity=32, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1787802, Length=127, Percent_Identity=37.7952755905512, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI87082007, Length=160, Percent_Identity=33.75, Blast_Score=76, Evalue=7e-15,
Organism=Escherichia coli, GI87081974, Length=154, Percent_Identity=33.1168831168831, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1788085, Length=171, Percent_Identity=29.2397660818713, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1787056, Length=179, Percent_Identity=32.9608938547486, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI1787410, Length=153, Percent_Identity=25.4901960784314, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330
- InterPro:   IPR000014
- InterPro:   IPR013767 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT; PF00989 PAS [H]

EC number: NA

Molecular weight: Translated: 62150; Mature: 62018

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGHHSKKNQSTGPVSIDVPMVGDPAHVLRGLLTAQVGIVCLSDSGDISFVSREFLAAFGQ
CCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHEEEEEEECCCCCHHHHHHHHHHHCC
QSLDPGTVIGQPYQAVFDAALEPYDISETRKTALATGLAVSKTQPDVAWSSNPAGGSIGI
CCCCCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHCCEEECCCCCCCCCCCCCCCEEEE
LTGSATELSQSAPMFEPDELTGLGNRKYLKACFEAIAQEDSGAIALFLDLDHFKQVNDTL
EECCHHHHHCCCCCCCCHHCCCCCCHHHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHH
GHAIGDKLLCKVADRLRKSVREGDIVVRIGGDEFAILLINWDQSAAEDVAARIIKVIGRP
HHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEEECCCHHHHHHHHHHHHHHCCC
FLIEGHQVTIGVSIGMAVRLPNERESEKLLQRADVALYESKRLGRNRFHWFKDAMLIELQ
EEEECCEEEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
QRRDTEIDLRKAVLLGQFGVVFQPQMNFQDQDITGFEALVRWNHPLRGVIAPIEFIEIAE
HHCCCCHHHHHHHHHHCCCEEECCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHH
ETGLIVEIGTWVLAEACQAAAGWPEDIAVAVNISPVQFEDEGFMVSVQTALQKSKLQPHR
HCCCEEEEHHHHHHHHHHHHCCCCCCEEEEEECCCEEECCCCCEEEHHHHHHHHCCCCCE
LELEITEATLLSNEEAVLARMNELQGLGIKISLDDFGIGYSSLNYLRKYPFDKVKIDQSF
EEEEEEHHHHHCCCHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHCCCCCEEECHHH
VREPFADESSHQIVEAVAHLGSALGMTVLAEGVETHEQMERIRSKGCASIQGYLVGRPIP
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCC
LDDITSFLTSLPNEIGGRKPLPAIQGDTT
HHHHHHHHHHCHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
GHHSKKNQSTGPVSIDVPMVGDPAHVLRGLLTAQVGIVCLSDSGDISFVSREFLAAFGQ
CCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHEEEEEEECCCCCHHHHHHHHHHHCC
QSLDPGTVIGQPYQAVFDAALEPYDISETRKTALATGLAVSKTQPDVAWSSNPAGGSIGI
CCCCCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHCCEEECCCCCCCCCCCCCCCEEEE
LTGSATELSQSAPMFEPDELTGLGNRKYLKACFEAIAQEDSGAIALFLDLDHFKQVNDTL
EECCHHHHHCCCCCCCCHHCCCCCCHHHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHH
GHAIGDKLLCKVADRLRKSVREGDIVVRIGGDEFAILLINWDQSAAEDVAARIIKVIGRP
HHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEEECCCHHHHHHHHHHHHHHCCC
FLIEGHQVTIGVSIGMAVRLPNERESEKLLQRADVALYESKRLGRNRFHWFKDAMLIELQ
EEEECCEEEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
QRRDTEIDLRKAVLLGQFGVVFQPQMNFQDQDITGFEALVRWNHPLRGVIAPIEFIEIAE
HHCCCCHHHHHHHHHHCCCEEECCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHH
ETGLIVEIGTWVLAEACQAAAGWPEDIAVAVNISPVQFEDEGFMVSVQTALQKSKLQPHR
HCCCEEEEHHHHHHHHHHHHCCCCCCEEEEEECCCEEECCCCCEEEHHHHHHHHCCCCCE
LELEITEATLLSNEEAVLARMNELQGLGIKISLDDFGIGYSSLNYLRKYPFDKVKIDQSF
EEEEEEHHHHHCCCHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHCCCCCEEECHHH
VREPFADESSHQIVEAVAHLGSALGMTVLAEGVETHEQMERIRSKGCASIQGYLVGRPIP
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCC
LDDITSFLTSLPNEIGGRKPLPAIQGDTT
HHHHHHHHHHCHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11259647 [H]