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The map label for this gene is cfa [H]

Identifier: 89054481

GI number: 89054481

Start: 1989500

End: 1990711

Strand: Direct

Name: cfa [H]

Synonym: Jann_1990

Alternate gene names: 89054481

Gene position: 1989500-1990711 (Clockwise)

Preceding gene: 89054480

Following gene: 89054482

Centisome position: 46.07

GC content: 58.83

Gene sequence:

>1212_bases
ATGACTGCACTGACGTCTCTGGAGGGGCAAAAGAACTTGCCCCGCTACTTCAAGGCTGTGTTTGAACAGGCCAAGGGGCT
GGAGCATGGACGCATCGACTTTCGCCTTCCCGATGGGCGTCTGTTCCGGGTGGAGGGCTCCAAACCCGGCCCGGTGGGGG
AGCTGGATATCCACAACGTCGACATCTTCGCGCGCCTGATCCGCGAGGGGGACCTGGGGTTCTGTGACGCCTACCTTGAT
GAATGGTGGTCCACGCCGGACTTGCAGGCCTTCCTGGACGTGGTCCACGCCGATAACGACGAGGTCTATGACGGTTTCCT
CGGCATGGGGCTGATCCGCGCCTATGAGAAATTCCGCTTCTGGTTGATCCGCAACACCAAGGCGCAGGCGAAGAAGAACA
TCTCGGCCCATTATGATCTGGGCAATGAGTTCTATGGCCTCTGGCTGGACGACACGATGACCTATTCCAGCGCGTTGTTT
GAGACGGGACAGGAAAGCCTTGAGGTGGCGCAGACGGCCAAATATGCCTCCATGGTCGATCAGATGGGGGCCGTGGCGGG
TGACCATGTGCTGGAGATCGGCTGCGGGTGGGGCGGCTTCGCCGAATACGCCGCGAAGGAGCGGGGCATCAAGGTCACGG
GCCTGACGATCAGCCAGGAACAGCATGATTATGCGGTCAAGCGCATTGCAGACGCGGGCCTCACCGACATGGTGGACATC
AAACTGCAGGACTACCGTGACGAACAGGGCACATATGACGGCATCGCCTCCATCGAGATGTTTGAGGCCGTCGGAGAGCA
ATATTGGCCCACCTATTTCGACACGCTCCGCAACCGCCTGAAGCCCGGCAAGGCAGCCACGTTGCAGATCATCACTGTGC
AGGATCGCCGATGGGACGTCTACAGAAAGGGCGTTGATTTCATTCAGAAATATATCTTTCCAGGCGGCATGCTGCCCGCC
CCAAAGGTGCTGGCCGAGCAGATTGAACGGGCGGGTCTGAGCATCGCGCATTCGGTGGAATTTGGCGAAAGCTACTCCCA
AACCTGCCGCCGCTGGCACGAGACATTCAACGCCAAATGGGACCAGATCGCAGCCATGGGCTTTGACGATCGGTTCCGGC
GGATGTGGAATTTCTATCTGACCTCTTGCGCGGCCACGTTCCATTTCGGAAACTGTGATGTGACGCAGATCACGGTTCGC
AAACCGGTCTGA

Upstream 100 bases:

>100_bases
CTGACGCCAATGTGTCAAAGAAATCTGACAGATCGCACGAATGTGGCTTGCCCAACCGGCACATGGCTTACATGTACGTG
ACTGGATTAAAGGGAAAATC

Downstream 100 bases:

>100_bases
GGCGGGCGCAGCCCTGTCCGGGCTCGGTCAATGGGCCGAATGAATGAGGGACAGGCACATGCCCACGGGCGCAAAACTGG
TCGGGGCGATCCTATTCTTT

Product: cyclopropane-fatty-acyl-phospholipid synthase

Products: NA

Alternate protein names: CFA synthase; Cyclopropane fatty acid synthase [H]

Number of amino acids: Translated: 403; Mature: 402

Protein sequence:

>403_residues
MTALTSLEGQKNLPRYFKAVFEQAKGLEHGRIDFRLPDGRLFRVEGSKPGPVGELDIHNVDIFARLIREGDLGFCDAYLD
EWWSTPDLQAFLDVVHADNDEVYDGFLGMGLIRAYEKFRFWLIRNTKAQAKKNISAHYDLGNEFYGLWLDDTMTYSSALF
ETGQESLEVAQTAKYASMVDQMGAVAGDHVLEIGCGWGGFAEYAAKERGIKVTGLTISQEQHDYAVKRIADAGLTDMVDI
KLQDYRDEQGTYDGIASIEMFEAVGEQYWPTYFDTLRNRLKPGKAATLQIITVQDRRWDVYRKGVDFIQKYIFPGGMLPA
PKVLAEQIERAGLSIAHSVEFGESYSQTCRRWHETFNAKWDQIAAMGFDDRFRRMWNFYLTSCAATFHFGNCDVTQITVR
KPV

Sequences:

>Translated_403_residues
MTALTSLEGQKNLPRYFKAVFEQAKGLEHGRIDFRLPDGRLFRVEGSKPGPVGELDIHNVDIFARLIREGDLGFCDAYLD
EWWSTPDLQAFLDVVHADNDEVYDGFLGMGLIRAYEKFRFWLIRNTKAQAKKNISAHYDLGNEFYGLWLDDTMTYSSALF
ETGQESLEVAQTAKYASMVDQMGAVAGDHVLEIGCGWGGFAEYAAKERGIKVTGLTISQEQHDYAVKRIADAGLTDMVDI
KLQDYRDEQGTYDGIASIEMFEAVGEQYWPTYFDTLRNRLKPGKAATLQIITVQDRRWDVYRKGVDFIQKYIFPGGMLPA
PKVLAEQIERAGLSIAHSVEFGESYSQTCRRWHETFNAKWDQIAAMGFDDRFRRMWNFYLTSCAATFHFGNCDVTQITVR
KPV
>Mature_402_residues
TALTSLEGQKNLPRYFKAVFEQAKGLEHGRIDFRLPDGRLFRVEGSKPGPVGELDIHNVDIFARLIREGDLGFCDAYLDE
WWSTPDLQAFLDVVHADNDEVYDGFLGMGLIRAYEKFRFWLIRNTKAQAKKNISAHYDLGNEFYGLWLDDTMTYSSALFE
TGQESLEVAQTAKYASMVDQMGAVAGDHVLEIGCGWGGFAEYAAKERGIKVTGLTISQEQHDYAVKRIADAGLTDMVDIK
LQDYRDEQGTYDGIASIEMFEAVGEQYWPTYFDTLRNRLKPGKAATLQIITVQDRRWDVYRKGVDFIQKYIFPGGMLPAP
KVLAEQIERAGLSIAHSVEFGESYSQTCRRWHETFNAKWDQIAAMGFDDRFRRMWNFYLTSCAATFHFGNCDVTQITVRK
PV

Specific function: Transfers a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge [H]

COG id: COG2230

COG function: function code M; Cyclopropane fatty acid synthase and related methyltransferases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CFA/CMAS family [H]

Homologues:

Organism=Escherichia coli, GI1787951, Length=371, Percent_Identity=33.6927223719677, Blast_Score=186, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI133904226, Length=383, Percent_Identity=36.8146214099217, Blast_Score=237, Evalue=1e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003333 [H]

Pfam domain/function: PF02353 CMAS [H]

EC number: =2.1.1.79 [H]

Molecular weight: Translated: 45927; Mature: 45796

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTALTSLEGQKNLPRYFKAVFEQAKGLEHGRIDFRLPDGRLFRVEGSKPGPVGELDIHNV
CCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCEEEEEECCCCCCCCCEECCHH
DIFARLIREGDLGFCDAYLDEWWSTPDLQAFLDVVHADNDEVYDGFLGMGLIRAYEKFRF
HHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHE
WLIRNTKAQAKKNISAHYDLGNEFYGLWLDDTMTYSSALFETGQESLEVAQTAKYASMVD
EEEECCHHHHHHCCCEEECCCCCEEEEEECCHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
QMGAVAGDHVLEIGCGWGGFAEYAAKERGIKVTGLTISQEQHDYAVKRIADAGLTDMVDI
HHHHHCCCCEEEEECCCCHHHHHHHHHCCEEEEEEEECCHHHHHHHHHHHHCCCCEEEEE
KLQDYRDEQGTYDGIASIEMFEAVGEQYWPTYFDTLRNRLKPGKAATLQIITVQDRRWDV
EEECCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCEEEEEEEEECCCHHH
YRKGVDFIQKYIFPGGMLPAPKVLAEQIERAGLSIAHSVEFGESYSQTCRRWHETFNAKW
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCEEEHHHCCHHHHHHHHHHHHHHCCCH
DQIAAMGFDDRFRRMWNFYLTSCAATFHFGNCDVTQITVRKPV
HHHHHCCCCHHHHHHHHHHHHHHHHHEECCCCCEEEEEEECCC
>Mature Secondary Structure 
TALTSLEGQKNLPRYFKAVFEQAKGLEHGRIDFRLPDGRLFRVEGSKPGPVGELDIHNV
CCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCEEEEEECCCCCCCCCEECCHH
DIFARLIREGDLGFCDAYLDEWWSTPDLQAFLDVVHADNDEVYDGFLGMGLIRAYEKFRF
HHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHE
WLIRNTKAQAKKNISAHYDLGNEFYGLWLDDTMTYSSALFETGQESLEVAQTAKYASMVD
EEEECCHHHHHHCCCEEECCCCCEEEEEECCHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
QMGAVAGDHVLEIGCGWGGFAEYAAKERGIKVTGLTISQEQHDYAVKRIADAGLTDMVDI
HHHHHCCCCEEEEECCCCHHHHHHHHHCCEEEEEEEECCHHHHHHHHHHHHCCCCEEEEE
KLQDYRDEQGTYDGIASIEMFEAVGEQYWPTYFDTLRNRLKPGKAATLQIITVQDRRWDV
EEECCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCEEEEEEEEECCCHHH
YRKGVDFIQKYIFPGGMLPAPKVLAEQIERAGLSIAHSVEFGESYSQTCRRWHETFNAKW
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCEEEHHHCCHHHHHHHHHHHHHHCCCH
DQIAAMGFDDRFRRMWNFYLTSCAATFHFGNCDVTQITVRKPV
HHHHHCCCCHHHHHHHHHHHHHHHHHEECCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]