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The map label for this gene is aglR [H]

Identifier: 89054436

GI number: 89054436

Start: 1935989

End: 1937023

Strand: Reverse

Name: aglR [H]

Synonym: Jann_1945

Alternate gene names: 89054436

Gene position: 1937023-1935989 (Counterclockwise)

Preceding gene: 89054443

Following gene: 89054435

Centisome position: 44.86

GC content: 66.09

Gene sequence:

>1035_bases
ATGAACCTCAGGGAGTTGTCCGAATCTCTCGGGCTGAGCCAGACCACCGTCAGCCGCGCTTTGAATGGCTACCCCGAGGT
GCGCGAAGCGACGCGCCTGCGGGTGCAGAAGGCGGCAGAGGCGGCGAACTACCTGCCCAACTCGCGGGCCCGCAGGCTGG
CAACGGGCCGCGCCATGGCCATCGGTCATGTGATGCCGCTTAACGGGCGGGAGGAGTTGGTGAACCCGATCTTTGCCGAT
TTCATCGCCGGTGCGGGGGAAGTCTATGGCAAGGACGGGTTCGACCTGCACCTGTCGATGGTCCCCGCAGATTGCACCGA
AGCCGCCTACAGGCAGATGGCGGCCAATGCGTCGGTCGATGCGGTCATGGTGCAGGCGCCCACATTGGATGATGCGCGCG
TGCCGCTGCTGAAAGATCTCGGGCTGCCCTTCCTGATCCATGGCCGCACCGCGGATCCGCAGGGCTACAGCTGGCTCGAC
GTCGCCAACGTCCGCGCCTTCCGCCGCGCCACCGATCTTCTGCTGGATCTGGGGCACCGACGGATCGCGCTTTTGAATGG
ACAGGAGACGCTGGATTTCGCCCTGCGCCGTCGGCGCGGGTTTGAAGAGGCCCTGACCGCCCGGGGCCTGACCCCCCGTC
CCGACTTCCTGCATTCGGACGTCATGACGGAGCAATACGGCTATCGCACGGCGCGCGCGCTGCTGGACCGCGATGACGCG
CCCACGGCCTTTGTCGTCTCGTCGATCATTCCGGCCATCGGCGTGCGTCGCGCCGCCGGAGAGCGCGGGCTGCGCACCGG
CCACGACATCTCGATCATCTGCCATGACGACGTGCTGAGTTATATCGACAACGATGGCATGAACGCCCCGGAAGGGCCGG
CCTTTACTGCCACCCGCTCCTCCATCCGTGCGGCGGGGCGGCGGTGCGCGGAGATCCTGCTCAGCCTCATCGACGATCCC
GACCAGCCCCATATTCAGGAGATCTGGGAGACTGATCTTACCCTCGGACGGTCCACGGGACCCGCTCCAACCTAG

Upstream 100 bases:

>100_bases
AATTCCAGAAGGCTGCGCGTGAAATTGTTTCTTTGACATTGGCCCCGCCCCTTGCATACCTTTCGCCGAAATTCCAAGCG
CTTTGAAAGACGCCGCAACC

Downstream 100 bases:

>100_bases
CGCGCCCAACGGTGCAGCAGCCCCCAGCGAAGGACACAATCATGGATTTCAAACGCTCCGATTTCCCGGAGGGCTTTCGC
TTCGGGGTCGCGACCTCCGC

Product: LacI family transcription regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 344; Mature: 344

Protein sequence:

>344_residues
MNLRELSESLGLSQTTVSRALNGYPEVREATRLRVQKAAEAANYLPNSRARRLATGRAMAIGHVMPLNGREELVNPIFAD
FIAGAGEVYGKDGFDLHLSMVPADCTEAAYRQMAANASVDAVMVQAPTLDDARVPLLKDLGLPFLIHGRTADPQGYSWLD
VANVRAFRRATDLLLDLGHRRIALLNGQETLDFALRRRRGFEEALTARGLTPRPDFLHSDVMTEQYGYRTARALLDRDDA
PTAFVVSSIIPAIGVRRAAGERGLRTGHDISIICHDDVLSYIDNDGMNAPEGPAFTATRSSIRAAGRRCAEILLSLIDDP
DQPHIQEIWETDLTLGRSTGPAPT

Sequences:

>Translated_344_residues
MNLRELSESLGLSQTTVSRALNGYPEVREATRLRVQKAAEAANYLPNSRARRLATGRAMAIGHVMPLNGREELVNPIFAD
FIAGAGEVYGKDGFDLHLSMVPADCTEAAYRQMAANASVDAVMVQAPTLDDARVPLLKDLGLPFLIHGRTADPQGYSWLD
VANVRAFRRATDLLLDLGHRRIALLNGQETLDFALRRRRGFEEALTARGLTPRPDFLHSDVMTEQYGYRTARALLDRDDA
PTAFVVSSIIPAIGVRRAAGERGLRTGHDISIICHDDVLSYIDNDGMNAPEGPAFTATRSSIRAAGRRCAEILLSLIDDP
DQPHIQEIWETDLTLGRSTGPAPT
>Mature_344_residues
MNLRELSESLGLSQTTVSRALNGYPEVREATRLRVQKAAEAANYLPNSRARRLATGRAMAIGHVMPLNGREELVNPIFAD
FIAGAGEVYGKDGFDLHLSMVPADCTEAAYRQMAANASVDAVMVQAPTLDDARVPLLKDLGLPFLIHGRTADPQGYSWLD
VANVRAFRRATDLLLDLGHRRIALLNGQETLDFALRRRRGFEEALTARGLTPRPDFLHSDVMTEQYGYRTARALLDRDDA
PTAFVVSSIIPAIGVRRAAGERGLRTGHDISIICHDDVLSYIDNDGMNAPEGPAFTATRSSIRAAGRRCAEILLSLIDDP
DQPHIQEIWETDLTLGRSTGPAPT

Specific function: Probable regulatory protein for the binding-protein- dependent transport system for alpha-glucosides such as sucrose, maltose and trehalose [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790369, Length=283, Percent_Identity=25.7950530035336, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1787580, Length=318, Percent_Identity=22.9559748427673, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1786540, Length=338, Percent_Identity=26.9230769230769, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1789068, Length=286, Percent_Identity=26.2237762237762, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1787948, Length=282, Percent_Identity=25.886524822695, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788474, Length=318, Percent_Identity=24.5283018867925, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1789202, Length=293, Percent_Identity=26.2798634812287, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI48994940, Length=230, Percent_Identity=25.6521739130435, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1787906, Length=274, Percent_Identity=25.1824817518248, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 37652; Mature: 37652

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLRELSESLGLSQTTVSRALNGYPEVREATRLRVQKAAEAANYLPNSRARRLATGRAMA
CCHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCHHH
IGHVMPLNGREELVNPIFADFIAGAGEVYGKDGFDLHLSMVPADCTEAAYRQMAANASVD
HCEEECCCCHHHHHHHHHHHHHHCCCHHCCCCCCEEEEEECCCHHHHHHHHHHHCCCCCC
AVMVQAPTLDDARVPLLKDLGLPFLIHGRTADPQGYSWLDVANVRAFRRATDLLLDLGHR
EEEEECCCCCCCCCCHHHHCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCC
RIALLNGQETLDFALRRRRGFEEALTARGLTPRPDFLHSDVMTEQYGYRTARALLDRDDA
EEEEECCCHHHHHHHHHHCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
PTAFVVSSIIPAIGVRRAAGERGLRTGHDISIICHDDVLSYIDNDGMNAPEGPAFTATRS
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECHHHHHHHCCCCCCCCCCCCCHHHHH
SIRAAGRRCAEILLSLIDDPDQPHIQEIWETDLTLGRSTGPAPT
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MNLRELSESLGLSQTTVSRALNGYPEVREATRLRVQKAAEAANYLPNSRARRLATGRAMA
CCHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCHHH
IGHVMPLNGREELVNPIFADFIAGAGEVYGKDGFDLHLSMVPADCTEAAYRQMAANASVD
HCEEECCCCHHHHHHHHHHHHHHCCCHHCCCCCCEEEEEECCCHHHHHHHHHHHCCCCCC
AVMVQAPTLDDARVPLLKDLGLPFLIHGRTADPQGYSWLDVANVRAFRRATDLLLDLGHR
EEEEECCCCCCCCCCHHHHCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCC
RIALLNGQETLDFALRRRRGFEEALTARGLTPRPDFLHSDVMTEQYGYRTARALLDRDDA
EEEEECCCHHHHHHHHHHCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
PTAFVVSSIIPAIGVRRAAGERGLRTGHDISIICHDDVLSYIDNDGMNAPEGPAFTATRS
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECHHHHHHHCCCCCCCCCCCCCHHHHH
SIRAAGRRCAEILLSLIDDPDQPHIQEIWETDLTLGRSTGPAPT
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10400573; 11481430 [H]