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The map label for this gene is sir1 [H]

Identifier: 89054264

GI number: 89054264

Start: 1760900

End: 1762561

Strand: Reverse

Name: sir1 [H]

Synonym: Jann_1773

Alternate gene names: 89054264

Gene position: 1762561-1760900 (Counterclockwise)

Preceding gene: 89054265

Following gene: 89054263

Centisome position: 40.82

GC content: 62.7

Gene sequence:

>1662_bases
ATGTACGCCTACACCGATTTCGACCGTGATTTTCTGGCCGAGCGCAACGCCCAGTTCCGCGCGCAGGTCGCGCGTCGCAT
CGACGGCTCCCTGACCGAGGATGAGTTCAAGCCCCTGCGCCTGATGAACGGTCTTTATCTGCAACTCCATGCCTACATGC
TGCGCGTCGCAATCCCCTATGGCACCCTGAACGCTGCACAAATGCGCCAGTTGGCGATGATCGCGGACCGGTGGGACAAG
GGCTATGGCCACTTCACCACGCGCCAGAATATCCAGTACAATTGGCCTGCGCTGCGCGACGTGCCCGATATGCTGGATGC
GTTGGGAGAGGTCGGGATGCACGCCATCCAGACCAGCGGCAACACGATCCGAAACGTGACCGCCGACCACTTCGCCAGTG
CCGCCGCCGAGGAGGTCGCGGACCCCCGCCCCGTGGCCGAACTGATCCGCCAATGGTCCACCGACCACTCGGAATTCCAG
TTCCTGCCGCGCAAATTCAAGGTTGCGGTGACGGGATCGGATCAGGACCGCGCGGTCACGGCCGCCCATGACATCGGTCT
GCGGCTGGTCAAGCGCGAGGGCGAGATCGGCGCGACGGTCCTGGTCGGTGGCGGCCTCGGACGGACGCCGATGATTGGCA
AGGTCCTGGCAGACTTCGTGGCGCTTGACGATCTTCTGCCGTATCTGGAGGCTGTCGTCGCGGTCTATAACCTGTTGGGA
CGGCGTGATAATAAGTACAAAGCGCGGATCAAGATCACCGTCCACGAGAATGGAATCGAGGAGATCCGACGTCTGGTGGA
GGCGGAGTTTGCCCCCCGCAAGGCCGCGTTCAACGGCGCGGACATGGCGATTCTGGAGAATATCCGCGCTGATTTCGCGG
CCCCGGATTTTACCGATGGCCAAGGCGCCTACCCCACCCACTACACCCACGATCCGGTCTTTCGCAGCTTTGTGGACACC
AACACCGTCGCCCATAGACACGCAGATTACGCGATCCTCACCGTGTCGTTGAAGGCCCACGGGGCCACGCCGGGCGATGC
GACCAGCGATCAAATGCGCACGCTCGCCGATATCGCGGAGCGTTTCGCCCATGATGAGCTGCGTATTTCCCATGAGCAAA
ACGTGATCCTGCCCCATATGCCCAAGCGGCACCTGCGCGCCGTTTTTGACCTGCTGCGCGCCGAGGGGTTGGGGACGGCG
AACATCGGGCTGGCGTCTGATATCATTGCCTGCCCCGGCATGGATTACTGCGCGCTGGCGACCGCCCGCTCCATCCCCGT
GGCGCAGGAGATTGCGACGCGGTTCGACGAGCTGAAGCTGGAACACGAGGTGGGTCCGTTGAAGATCAAGATCTCGGGCT
GCATCAATGCCTGCGGGCACCACCATGTGGGGCATATCGGCATCCTGGGCCTCGACCGCGCGGGGGTGGAGAACTACCAG
ATCACCCTTGGTGGCGACGGCGGTCCGGATGCCGTGATCGGCGAACGGGCCGGGCCGGGATTTGCCTATGATGAGGTGGT
GGATGCGATTGAGCGGCTGGTGCGGGCCTATCTTGAGGTGCGTGACAATGCCGACGAGACATTCCTTGAGACCTACCGCC
GCCTCGGCGCCGCACCGTTCAAAGCTGCACTTTATCCCGAGGTGAAAGCCAATGCCGCTTAA

Upstream 100 bases:

>100_bases
CCCCGAGCCGGTCCATTTCCGCGAGGCGTTTCGCACGCGCGGCCCATCGAACTATGCCCACGGCAAGCAAACCGACCTGA
CCGAGCAGGAGGCCTGAACC

Downstream 100 bases:

>100_bases
GGAACTTGCTGAGCGCCGCACGCTTCTGCACCGCAAGAGTGACGCGCAGACCGTGCTGGCCCATGCGCTTGATGATTTGG
CCATCGGCCCGGTCGCCATG

Product: nitrite/sulfite reductase, hemoprotein beta-component, ferrodoxin-like

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 553; Mature: 553

Protein sequence:

>553_residues
MYAYTDFDRDFLAERNAQFRAQVARRIDGSLTEDEFKPLRLMNGLYLQLHAYMLRVAIPYGTLNAAQMRQLAMIADRWDK
GYGHFTTRQNIQYNWPALRDVPDMLDALGEVGMHAIQTSGNTIRNVTADHFASAAAEEVADPRPVAELIRQWSTDHSEFQ
FLPRKFKVAVTGSDQDRAVTAAHDIGLRLVKREGEIGATVLVGGGLGRTPMIGKVLADFVALDDLLPYLEAVVAVYNLLG
RRDNKYKARIKITVHENGIEEIRRLVEAEFAPRKAAFNGADMAILENIRADFAAPDFTDGQGAYPTHYTHDPVFRSFVDT
NTVAHRHADYAILTVSLKAHGATPGDATSDQMRTLADIAERFAHDELRISHEQNVILPHMPKRHLRAVFDLLRAEGLGTA
NIGLASDIIACPGMDYCALATARSIPVAQEIATRFDELKLEHEVGPLKIKISGCINACGHHHVGHIGILGLDRAGVENYQ
ITLGGDGGPDAVIGERAGPGFAYDEVVDAIERLVRAYLEVRDNADETFLETYRRLGAAPFKAALYPEVKANAA

Sequences:

>Translated_553_residues
MYAYTDFDRDFLAERNAQFRAQVARRIDGSLTEDEFKPLRLMNGLYLQLHAYMLRVAIPYGTLNAAQMRQLAMIADRWDK
GYGHFTTRQNIQYNWPALRDVPDMLDALGEVGMHAIQTSGNTIRNVTADHFASAAAEEVADPRPVAELIRQWSTDHSEFQ
FLPRKFKVAVTGSDQDRAVTAAHDIGLRLVKREGEIGATVLVGGGLGRTPMIGKVLADFVALDDLLPYLEAVVAVYNLLG
RRDNKYKARIKITVHENGIEEIRRLVEAEFAPRKAAFNGADMAILENIRADFAAPDFTDGQGAYPTHYTHDPVFRSFVDT
NTVAHRHADYAILTVSLKAHGATPGDATSDQMRTLADIAERFAHDELRISHEQNVILPHMPKRHLRAVFDLLRAEGLGTA
NIGLASDIIACPGMDYCALATARSIPVAQEIATRFDELKLEHEVGPLKIKISGCINACGHHHVGHIGILGLDRAGVENYQ
ITLGGDGGPDAVIGERAGPGFAYDEVVDAIERLVRAYLEVRDNADETFLETYRRLGAAPFKAALYPEVKANAA
>Mature_553_residues
MYAYTDFDRDFLAERNAQFRAQVARRIDGSLTEDEFKPLRLMNGLYLQLHAYMLRVAIPYGTLNAAQMRQLAMIADRWDK
GYGHFTTRQNIQYNWPALRDVPDMLDALGEVGMHAIQTSGNTIRNVTADHFASAAAEEVADPRPVAELIRQWSTDHSEFQ
FLPRKFKVAVTGSDQDRAVTAAHDIGLRLVKREGEIGATVLVGGGLGRTPMIGKVLADFVALDDLLPYLEAVVAVYNLLG
RRDNKYKARIKITVHENGIEEIRRLVEAEFAPRKAAFNGADMAILENIRADFAAPDFTDGQGAYPTHYTHDPVFRSFVDT
NTVAHRHADYAILTVSLKAHGATPGDATSDQMRTLADIAERFAHDELRISHEQNVILPHMPKRHLRAVFDLLRAEGLGTA
NIGLASDIIACPGMDYCALATARSIPVAQEIATRFDELKLEHEVGPLKIKISGCINACGHHHVGHIGILGLDRAGVENYQ
ITLGGDGGPDAVIGERAGPGFAYDEVVDAIERLVRAYLEVRDNADETFLETYRRLGAAPFKAALYPEVKANAA

Specific function: This Enzyme Catalyzes The 6-Electron Reduction Of Sulfite To Sulfide. This Is One Of Several Activities Required For The Biosynthesis Of L-Cysteine From Sulfate. [C]

COG id: COG0155

COG function: function code P; Sulfite reductase, beta subunit (hemoprotein)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family [H]

Homologues:

Organism=Escherichia coli, GI1789122, Length=471, Percent_Identity=25.2653927813163, Blast_Score=86, Evalue=8e-18,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005117
- InterPro:   IPR006067
- InterPro:   IPR006066 [H]

Pfam domain/function: PF01077 NIR_SIR; PF03460 NIR_SIR_ferr [H]

EC number: =1.8.7.1 [H]

Molecular weight: Translated: 61033; Mature: 61033

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYAYTDFDRDFLAERNAQFRAQVARRIDGSLTEDEFKPLRLMNGLYLQLHAYMLRVAIPY
CCCCCCCCHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
GTLNAAQMRQLAMIADRWDKGYGHFTTRQNIQYNWPALRDVPDMLDALGEVGMHAIQTSG
CCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHCCC
NTIRNVTADHFASAAAEEVADPRPVAELIRQWSTDHSEFQFLPRKFKVAVTGSDQDRAVT
CCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHCCCEEEEEEECCCCCCEEH
AAHDIGLRLVKREGEIGATVLVGGGLGRTPMIGKVLADFVALDDLLPYLEAVVAVYNLLG
HHHHHHHHEEECCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
RRDNKYKARIKITVHENGIEEIRRLVEAEFAPRKAAFNGADMAILENIRADFAAPDFTDG
CCCCCEEEEEEEEEECCCHHHHHHHHHHHCCCCHHCCCCCHHHHHHHHHHHCCCCCCCCC
QGAYPTHYTHDPVFRSFVDTNTVAHRHADYAILTVSLKAHGATPGDATSDQMRTLADIAE
CCCCCCCCCCCHHHHHHHHCCHHHHHCCCEEEEEEEEEECCCCCCCCCHHHHHHHHHHHH
RFAHDELRISHEQNVILPHMPKRHLRAVFDLLRAEGLGTANIGLASDIIACPGMDYCALA
HHCCHHHEECCCCCEECCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCHHHHH
TARSIPVAQEIATRFDELKLEHEVGPLKIKISGCINACGHHHVGHIGILGLDRAGVENYQ
HHCCCCHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHCCCCCCCEEEEEECCCCCCCCEE
ITLGGDGGPDAVIGERAGPGFAYDEVVDAIERLVRAYLEVRDNADETFLETYRRLGAAPF
EEECCCCCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCC
KAALYPEVKANAA
HHHCCCCCCCCCC
>Mature Secondary Structure
MYAYTDFDRDFLAERNAQFRAQVARRIDGSLTEDEFKPLRLMNGLYLQLHAYMLRVAIPY
CCCCCCCCHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
GTLNAAQMRQLAMIADRWDKGYGHFTTRQNIQYNWPALRDVPDMLDALGEVGMHAIQTSG
CCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHCCC
NTIRNVTADHFASAAAEEVADPRPVAELIRQWSTDHSEFQFLPRKFKVAVTGSDQDRAVT
CCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHCCCEEEEEEECCCCCCEEH
AAHDIGLRLVKREGEIGATVLVGGGLGRTPMIGKVLADFVALDDLLPYLEAVVAVYNLLG
HHHHHHHHEEECCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
RRDNKYKARIKITVHENGIEEIRRLVEAEFAPRKAAFNGADMAILENIRADFAAPDFTDG
CCCCCEEEEEEEEEECCCHHHHHHHHHHHCCCCHHCCCCCHHHHHHHHHHHCCCCCCCCC
QGAYPTHYTHDPVFRSFVDTNTVAHRHADYAILTVSLKAHGATPGDATSDQMRTLADIAE
CCCCCCCCCCCHHHHHHHHCCHHHHHCCCEEEEEEEEEECCCCCCCCCHHHHHHHHHHHH
RFAHDELRISHEQNVILPHMPKRHLRAVFDLLRAEGLGTANIGLASDIIACPGMDYCALA
HHCCHHHEECCCCCEECCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCHHHHH
TARSIPVAQEIATRFDELKLEHEVGPLKIKISGCINACGHHHVGHIGILGLDRAGVENYQ
HHCCCCHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHCCCCCCCEEEEEECCCCCCCCEE
ITLGGDGGPDAVIGERAGPGFAYDEVVDAIERLVRAYLEVRDNADETFLETYRRLGAAPF
EEECCCCCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCC
KAALYPEVKANAA
HHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA