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The map label for this gene is dctB [H]

Identifier: 89054222

GI number: 89054222

Start: 1722982

End: 1724847

Strand: Reverse

Name: dctB [H]

Synonym: Jann_1731

Alternate gene names: 89054222

Gene position: 1724847-1722982 (Counterclockwise)

Preceding gene: 89054224

Following gene: 89054221

Centisome position: 39.95

GC content: 66.56

Gene sequence:

>1866_bases
ATGCGTGACCGGCCCGCACCCGTTCCTTTGACCCGTCCCCGCGCGACCCGATCGCGCCGGGCGATCTGGGCCGTGGTGCT
GGCGGCCCTTCTGGCGCTTGGCGCGATATTGGCCGCTCTGCCCCGGATCGAGCGCTTTTACCTCCGCCAGGCCGGGACCG
AACATGCGGCCACTCTGGCCCTTGCCACCCAGGTCCTGCGCGGCGCGCTGGAGCGCACGCAAGCGCTGCCCGCCCTGATC
GCGGACCGCACGATTTTGCAACAGCTGCTGGCCGAGCCCGACAATGACGGCATCGTGCCCTTCACCAATGAGTTGTTGCG
CCAATCCGCCCTGTCGCTTGATGTCTCCGATATCTACGTGCTCGATACCGAGGGGCGCACCATTGCGTCGTCCAATTATC
GCACCGATCATTCCTTCATCGGCCAGAGCTTCGCCTACCGCCCCTATTTCCTCGACGCCATGGATGCGGGGTTGGGTCGG
TTCCACGCCCTTGGCACGACATCCGGCCAGCGTGGGTATTTCTTCGCCTCCCCAGTGATCGAGAACACGCGGATCATCGG
CGTTGTCGTCGTCAAGCTGCGCCTTGATGTGTTTGAAGAGGCCTGGGCCGCATCTGACGCGACGGTGATGGTGACCGATA
TCAACAACGTGATTTTCCTGTCCGACCGCCAGGATTGGCACTTTCGCACCACATCCCCCCTGCGCGAGCCGGTGCGGAAC
CTGATCGCGCGCACCCGGCAATACCCCGTGTCGATGCTGTCGCCCCTTGGCCTCGACGTCGCCCCCCTTGACCCTGATCT
GGGCCCTGACCTGGAGCTGGTGGCTGTGGGGGATGAAAGTTTCGTGCGCCAGACCACCCTGATCGCCGCCCCCGGATGGC
GGGTCAGCATCCTGACGCCCACAGGGCCTGCCCTGCAACAGGCCTGGACCGCCGCGCTGTTGCTGGCGCTGGTTGTCGTT
ATGCTCGGCTTTGTGGCGGCCACCATGCTTGGACGGCGCGCGCGGTTGATCGAGCGGTTGGCGGCAGAGCAATCGCTGGC
CAGCCTGCTGGAGGCCCGCGTGACCGAGCGGACCGGAGAGTTGAAGGCCGAGGTGGAGGAGCGTCGCGCGACCGAGGCGC
GTTTGCGCAAGACCCAGGCGGAGCTGGTGCAGGCGGGCAAGCTGGCGGCCCTTGGGCAAATGTCCGCCGCACTTAGCCAT
GAGTTCAATCAGCCGCTGGCGGCGGTCAAATCCTACGCTGAGAATGCGGGCACCTTCCTGGATCGGGGCCGCATGGATGA
GGCGCGCGGCAATATTCAGCGGATCAGCGGTTTGGCCGACCGGATGGCCGCAATATCCAAACACCTGCGCAACTTCGCGC
GGCGCCCCGGTGACAAGACCGGCCCGGTGCCGCTCCGGCCCGTGATCGCAGATGCATTGGAGTTGATGGCCCCGCGCCTG
CGCGACGCGGATGTGCGCTATGATCCGCCCCGGGTCGAGGTTTGGGCGCGCGGCGGTCGGGTGCGCCTGCAACAGGTGGT
GGTGAACCTTCTGGGCAATGCGCTGGACGCGATGGCCCAGGTGGATCCTCCGACAATCGAGATCACGCTGACGGGCGGCG
ACGCCCCGCAGATCGCCGTGCGCGACATCGGCCCCGGCCTCTCGGACGAGGCGCTGGCCCATGCCTTCGATCCCTTTTTC
ACCACCAAGGAGCCGGGACAGGGCCTTGGGCTCGGCCTGTCGATCTCCTACAATATCATCGGCGACTTTGGGGGGCGTTT
GTCGGCCGAGAACCACGCCGGGGGCGGCGCGATCTTCCGCGTCACGCTGGAGGCCGCCACGCCTCAGGCCCCGGGTCTTG
AAGCACGGGAGCTGGCCGCCGAATGA

Upstream 100 bases:

>100_bases
GCGCGGGGAAATTTCTGCGATCGTGGACGCAAGCGCCAAGCCCGCCCCGGGTGCCGCGTTCCCCTAGTCAGCCTGCCAGC
GGCCTGCCATAGATGGGGCC

Downstream 100 bases:

>100_bases
CCCAAACGCCCGTCCTTTTCGTCGATGATGAGCCTGATCTGCGGATCGCGGGCGAGCAGACCCTGTCACTGGCCGATCTG
CCGGTCATTGCCTGCGCCCG

Product: periplasmic sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 621; Mature: 621

Protein sequence:

>621_residues
MRDRPAPVPLTRPRATRSRRAIWAVVLAALLALGAILAALPRIERFYLRQAGTEHAATLALATQVLRGALERTQALPALI
ADRTILQQLLAEPDNDGIVPFTNELLRQSALSLDVSDIYVLDTEGRTIASSNYRTDHSFIGQSFAYRPYFLDAMDAGLGR
FHALGTTSGQRGYFFASPVIENTRIIGVVVVKLRLDVFEEAWAASDATVMVTDINNVIFLSDRQDWHFRTTSPLREPVRN
LIARTRQYPVSMLSPLGLDVAPLDPDLGPDLELVAVGDESFVRQTTLIAAPGWRVSILTPTGPALQQAWTAALLLALVVV
MLGFVAATMLGRRARLIERLAAEQSLASLLEARVTERTGELKAEVEERRATEARLRKTQAELVQAGKLAALGQMSAALSH
EFNQPLAAVKSYAENAGTFLDRGRMDEARGNIQRISGLADRMAAISKHLRNFARRPGDKTGPVPLRPVIADALELMAPRL
RDADVRYDPPRVEVWARGGRVRLQQVVVNLLGNALDAMAQVDPPTIEITLTGGDAPQIAVRDIGPGLSDEALAHAFDPFF
TTKEPGQGLGLGLSISYNIIGDFGGRLSAENHAGGGAIFRVTLEAATPQAPGLEARELAAE

Sequences:

>Translated_621_residues
MRDRPAPVPLTRPRATRSRRAIWAVVLAALLALGAILAALPRIERFYLRQAGTEHAATLALATQVLRGALERTQALPALI
ADRTILQQLLAEPDNDGIVPFTNELLRQSALSLDVSDIYVLDTEGRTIASSNYRTDHSFIGQSFAYRPYFLDAMDAGLGR
FHALGTTSGQRGYFFASPVIENTRIIGVVVVKLRLDVFEEAWAASDATVMVTDINNVIFLSDRQDWHFRTTSPLREPVRN
LIARTRQYPVSMLSPLGLDVAPLDPDLGPDLELVAVGDESFVRQTTLIAAPGWRVSILTPTGPALQQAWTAALLLALVVV
MLGFVAATMLGRRARLIERLAAEQSLASLLEARVTERTGELKAEVEERRATEARLRKTQAELVQAGKLAALGQMSAALSH
EFNQPLAAVKSYAENAGTFLDRGRMDEARGNIQRISGLADRMAAISKHLRNFARRPGDKTGPVPLRPVIADALELMAPRL
RDADVRYDPPRVEVWARGGRVRLQQVVVNLLGNALDAMAQVDPPTIEITLTGGDAPQIAVRDIGPGLSDEALAHAFDPFF
TTKEPGQGLGLGLSISYNIIGDFGGRLSAENHAGGGAIFRVTLEAATPQAPGLEARELAAE
>Mature_621_residues
MRDRPAPVPLTRPRATRSRRAIWAVVLAALLALGAILAALPRIERFYLRQAGTEHAATLALATQVLRGALERTQALPALI
ADRTILQQLLAEPDNDGIVPFTNELLRQSALSLDVSDIYVLDTEGRTIASSNYRTDHSFIGQSFAYRPYFLDAMDAGLGR
FHALGTTSGQRGYFFASPVIENTRIIGVVVVKLRLDVFEEAWAASDATVMVTDINNVIFLSDRQDWHFRTTSPLREPVRN
LIARTRQYPVSMLSPLGLDVAPLDPDLGPDLELVAVGDESFVRQTTLIAAPGWRVSILTPTGPALQQAWTAALLLALVVV
MLGFVAATMLGRRARLIERLAAEQSLASLLEARVTERTGELKAEVEERRATEARLRKTQAELVQAGKLAALGQMSAALSH
EFNQPLAAVKSYAENAGTFLDRGRMDEARGNIQRISGLADRMAAISKHLRNFARRPGDKTGPVPLRPVIADALELMAPRL
RDADVRYDPPRVEVWARGGRVRLQQVVVNLLGNALDAMAQVDPPTIEITLTGGDAPQIAVRDIGPGLSDEALAHAFDPFF
TTKEPGQGLGLGLSISYNIIGDFGGRLSAENHAGGGAIFRVTLEAATPQAPGLEARELAAE

Specific function: Member of the two-component regulatory system dctB/dctD involved in the transport of C4-dicarboxylates. DctB functions as a membrane-associated protein kinase that phosphorylates dctD in response to environmental signals [H]

COG id: COG4191

COG function: function code T; Signal transduction histidine kinase regulating C4-dicarboxylate transport system

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=228, Percent_Identity=28.9473684210526, Blast_Score=86, Evalue=8e-18,
Organism=Escherichia coli, GI1788549, Length=266, Percent_Identity=27.4436090225564, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87081816, Length=277, Percent_Identity=29.9638989169675, Blast_Score=73, Evalue=7e-14,
Organism=Escherichia coli, GI145693157, Length=263, Percent_Identity=28.1368821292776, Blast_Score=67, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR017055
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 67354; Mature: 67354

Theoretical pI: Translated: 6.75; Mature: 6.75

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDRPAPVPLTRPRATRSRRAIWAVVLAALLALGAILAALPRIERFYLRQAGTEHAATLA
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
LATQVLRGALERTQALPALIADRTILQQLLAEPDNDGIVPFTNELLRQSALSLDVSDIYV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCEEEE
LDTEGRTIASSNYRTDHSFIGQSFAYRPYFLDAMDAGLGRFHALGTTSGQRGYFFASPVI
EECCCCEEECCCCCCHHHHHCCCCCCCCEEHHHHHCCCHHHEEECCCCCCCCEEEECCCC
ENTRIIGVVVVKLRLDVFEEAWAASDATVMVTDINNVIFLSDRQDWHFRTTSPLREPVRN
CCCEEEEHEEEHHHHHHHHHHHCCCCCEEEEEECCCEEEEECCCCCCEECCHHHHHHHHH
LIARTRQYPVSMLSPLGLDVAPLDPDLGPDLELVAVGDESFVRQTTLIAAPGWRVSILTP
HHHHHHCCCHHHHCCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHEEEECCCCEEEEECC
TGPALQQAWTAALLLALVVVMLGFVAATMLGRRARLIERLAAEQSLASLLEARVTERTGE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKAEVEERRATEARLRKTQAELVQAGKLAALGQMSAALSHEFNQPLAAVKSYAENAGTFL
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
DRGRMDEARGNIQRISGLADRMAAISKHLRNFARRPGDKTGPVPLRPVIADALELMAPRL
HCCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCC
RDADVRYDPPRVEVWARGGRVRLQQVVVNLLGNALDAMAQVDPPTIEITLTGGDAPQIAV
CCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCEEEE
RDIGPGLSDEALAHAFDPFFTTKEPGQGLGLGLSISYNIIGDFGGRLSAENHAGGGAIFR
ECCCCCCCHHHHHHHHCCCCCCCCCCCCCEEEEEEEEEEEECCCCCCCCCCCCCCCEEEE
VTLEAATPQAPGLEARELAAE
EEEECCCCCCCCCCHHHHCCC
>Mature Secondary Structure
MRDRPAPVPLTRPRATRSRRAIWAVVLAALLALGAILAALPRIERFYLRQAGTEHAATLA
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
LATQVLRGALERTQALPALIADRTILQQLLAEPDNDGIVPFTNELLRQSALSLDVSDIYV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCEEEE
LDTEGRTIASSNYRTDHSFIGQSFAYRPYFLDAMDAGLGRFHALGTTSGQRGYFFASPVI
EECCCCEEECCCCCCHHHHHCCCCCCCCEEHHHHHCCCHHHEEECCCCCCCCEEEECCCC
ENTRIIGVVVVKLRLDVFEEAWAASDATVMVTDINNVIFLSDRQDWHFRTTSPLREPVRN
CCCEEEEHEEEHHHHHHHHHHHCCCCCEEEEEECCCEEEEECCCCCCEECCHHHHHHHHH
LIARTRQYPVSMLSPLGLDVAPLDPDLGPDLELVAVGDESFVRQTTLIAAPGWRVSILTP
HHHHHHCCCHHHHCCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHEEEECCCCEEEEECC
TGPALQQAWTAALLLALVVVMLGFVAATMLGRRARLIERLAAEQSLASLLEARVTERTGE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKAEVEERRATEARLRKTQAELVQAGKLAALGQMSAALSHEFNQPLAAVKSYAENAGTFL
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
DRGRMDEARGNIQRISGLADRMAAISKHLRNFARRPGDKTGPVPLRPVIADALELMAPRL
HCCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCC
RDADVRYDPPRVEVWARGGRVRLQQVVVNLLGNALDAMAQVDPPTIEITLTGGDAPQIAV
CCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCEEEE
RDIGPGLSDEALAHAFDPFFTTKEPGQGLGLGLSISYNIIGDFGGRLSAENHAGGGAIFR
ECCCCCCCHHHHHHHHCCCCCCCCCCCCCEEEEEEEEEEEECCCCCCCCCCCCCCCEEEE
VTLEAATPQAPGLEARELAAE
EEEECCCCCCCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2134335; 2793824; 11481431; 2551890; 2695394 [H]