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The map label for this gene is gapB [H]

Identifier: 89054189

GI number: 89054189

Start: 1680112

End: 1681116

Strand: Reverse

Name: gapB [H]

Synonym: Jann_1698

Alternate gene names: 89054189

Gene position: 1681116-1680112 (Counterclockwise)

Preceding gene: 89054191

Following gene: 89054187

Centisome position: 38.93

GC content: 64.68

Gene sequence:

>1005_bases
ATGACGGTCACACTCGGCATCAACGGTTTCGGCCGCATCGGACGGGCCACGCTGGCCTATATCGCCGAGAGCGCGCGCAA
TGATGTGCAGGTGGTCAAGATCAACGCGACGGGCCCGGTGGAGACCTCCGCCCATCTGCTGCGTTACGATTCGGTCCATG
GCCGCTTCCCCGGAGAGGTCCGGGTGGACGGCGACACGATGGACCTTGGGCGCGGGCCGATGAAAATGTTCTCCACCTAC
GATCCGGCACAGCTGGATTGGGATGGCTGCGATGTGGTGCTGGAATGCACCGGCAAGTTCAACGACGGCCATAAATCGGC
AGTGCATCTTGAGCGCGGCGCGAAGAAGGTGCTGATCTCTGCACCGGCCACGAATGTCGACCGCACCGTTGTGTACGGCG
TGAACCATCGCGAGATGCGGGCGGAGGAGCGGATGATCTCCAACGGGTCCTGCACCACCAATTGCCTGGCCCCCCTGGTG
AAGGTGCTGAATGACGCGATTGGCGTTGAGCGGGGCATCATGACCACGATCCACAGCTACACCGGCGATCAGCCGACGCT
GGACCGCCGCCACGATGACCTCTACCGCGCGCGCGCCGCAGCGATGGCCATGATCCCCACCTCCACCGGGGCCGCGAAAG
CCTTGGCCGAGGTCCTGCCCGAGATGGCGGGGCGCCTGGATGGCACCGCCCTGCGCGTGCCCACGCCCAATGTCTCCGCC
GTCGATCTAACGTTCGAGGCGGCCCGCGATGTCACGGTTAACGACGTTAACGATATCGTGGCGGAGGCGGCGAACGGCCA
TATGGGGGCAGTCCTGTCCTATGATCCCGAACCCAAGGTTTCCGTCGACTTCAACCACACCACGCCGTCATCCATCTTTG
CGCCGGACCAGACCAAGGTCGTCGGCGGGCGCACCGTGCGGGTGCTGGCATGGTACGACAACGAATGGGGTTTTTCGGCG
CGCATGGCCGACGTGGCCGGCGCGATGGGCCGGTTGCTGCACTGA

Upstream 100 bases:

>100_bases
CGCCACCGTTTCCGCTAACATGCCGAAATCACGCTCTTTTCGGGTTCCATCGCAGGGCCCGCCGCCCTACCAATTGCGCC
GAAATAGCAAGGAGCGCCCC

Downstream 100 bases:

>100_bases
CGCCTATGCCAGCGGAAGGCCGTGGGTCAGCCGCTGTTTGACCGGGTCCAGGATTTCCACCGTCGTACAATGGAGCCGCC
CACTGCCCGCGTCTTCGACA

Product: glyceraldehyde-3-phosphate dehydrogenase

Products: NA

Alternate protein names: GAPDH [H]

Number of amino acids: Translated: 334; Mature: 333

Protein sequence:

>334_residues
MTVTLGINGFGRIGRATLAYIAESARNDVQVVKINATGPVETSAHLLRYDSVHGRFPGEVRVDGDTMDLGRGPMKMFSTY
DPAQLDWDGCDVVLECTGKFNDGHKSAVHLERGAKKVLISAPATNVDRTVVYGVNHREMRAEERMISNGSCTTNCLAPLV
KVLNDAIGVERGIMTTIHSYTGDQPTLDRRHDDLYRARAAAMAMIPTSTGAAKALAEVLPEMAGRLDGTALRVPTPNVSA
VDLTFEAARDVTVNDVNDIVAEAANGHMGAVLSYDPEPKVSVDFNHTTPSSIFAPDQTKVVGGRTVRVLAWYDNEWGFSA
RMADVAGAMGRLLH

Sequences:

>Translated_334_residues
MTVTLGINGFGRIGRATLAYIAESARNDVQVVKINATGPVETSAHLLRYDSVHGRFPGEVRVDGDTMDLGRGPMKMFSTY
DPAQLDWDGCDVVLECTGKFNDGHKSAVHLERGAKKVLISAPATNVDRTVVYGVNHREMRAEERMISNGSCTTNCLAPLV
KVLNDAIGVERGIMTTIHSYTGDQPTLDRRHDDLYRARAAAMAMIPTSTGAAKALAEVLPEMAGRLDGTALRVPTPNVSA
VDLTFEAARDVTVNDVNDIVAEAANGHMGAVLSYDPEPKVSVDFNHTTPSSIFAPDQTKVVGGRTVRVLAWYDNEWGFSA
RMADVAGAMGRLLH
>Mature_333_residues
TVTLGINGFGRIGRATLAYIAESARNDVQVVKINATGPVETSAHLLRYDSVHGRFPGEVRVDGDTMDLGRGPMKMFSTYD
PAQLDWDGCDVVLECTGKFNDGHKSAVHLERGAKKVLISAPATNVDRTVVYGVNHREMRAEERMISNGSCTTNCLAPLVK
VLNDAIGVERGIMTTIHSYTGDQPTLDRRHDDLYRARAAAMAMIPTSTGAAKALAEVLPEMAGRLDGTALRVPTPNVSAV
DLTFEAARDVTVNDVNDIVAEAANGHMGAVLSYDPEPKVSVDFNHTTPSSIFAPDQTKVVGGRTVRVLAWYDNEWGFSAR
MADVAGAMGRLLH

Specific function: Could Play A Role In Pyridoxal 5'-Phosphate Synthesis. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=331, Percent_Identity=40.1812688821752, Blast_Score=249, Evalue=3e-66,
Organism=Homo sapiens, GI7657116, Length=333, Percent_Identity=39.3393393393393, Blast_Score=228, Evalue=7e-60,
Organism=Escherichia coli, GI1789295, Length=334, Percent_Identity=44.311377245509, Blast_Score=287, Evalue=7e-79,
Organism=Escherichia coli, GI1788079, Length=328, Percent_Identity=42.3780487804878, Blast_Score=256, Evalue=1e-69,
Organism=Caenorhabditis elegans, GI17534679, Length=335, Percent_Identity=43.2835820895522, Blast_Score=262, Evalue=2e-70,
Organism=Caenorhabditis elegans, GI17534677, Length=335, Percent_Identity=42.9850746268657, Blast_Score=261, Evalue=3e-70,
Organism=Caenorhabditis elegans, GI32566163, Length=332, Percent_Identity=43.0722891566265, Blast_Score=261, Evalue=3e-70,
Organism=Caenorhabditis elegans, GI17568413, Length=332, Percent_Identity=43.0722891566265, Blast_Score=261, Evalue=4e-70,
Organism=Saccharomyces cerevisiae, GI6322409, Length=329, Percent_Identity=42.2492401215805, Blast_Score=254, Evalue=1e-68,
Organism=Saccharomyces cerevisiae, GI6322468, Length=329, Percent_Identity=41.6413373860182, Blast_Score=251, Evalue=1e-67,
Organism=Saccharomyces cerevisiae, GI6321631, Length=329, Percent_Identity=42.2492401215805, Blast_Score=250, Evalue=3e-67,
Organism=Drosophila melanogaster, GI17933600, Length=329, Percent_Identity=41.9452887537994, Blast_Score=250, Evalue=1e-66,
Organism=Drosophila melanogaster, GI18110149, Length=329, Percent_Identity=41.9452887537994, Blast_Score=250, Evalue=1e-66,
Organism=Drosophila melanogaster, GI85725000, Length=330, Percent_Identity=42.1212121212121, Blast_Score=245, Evalue=3e-65,
Organism=Drosophila melanogaster, GI22023983, Length=330, Percent_Identity=42.1212121212121, Blast_Score=245, Evalue=3e-65,
Organism=Drosophila melanogaster, GI19922412, Length=330, Percent_Identity=39.6969696969697, Blast_Score=238, Evalue=3e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 35997; Mature: 35866

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVTLGINGFGRIGRATLAYIAESARNDVQVVKINATGPVETSAHLLRYDSVHGRFPGEV
CEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHEEECCCCCCCCCEE
RVDGDTMDLGRGPMKMFSTYDPAQLDWDGCDVVLECTGKFNDGHKSAVHLERGAKKVLIS
EECCCCEECCCCCHHHHCCCCCCEECCCCCEEEEEECCCCCCCCCCEEEECCCCCEEEEE
APATNVDRTVVYGVNHREMRAEERMISNGSCTTNCLAPLVKVLNDAIGVERGIMTTIHSY
CCCCCCCCEEEEECCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHC
TGDQPTLDRRHDDLYRARAAAMAMIPTSTGAAKALAEVLPEMAGRLDGTALRVPTPNVSA
CCCCCCCCCHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHCCCCCCEEECCCCCCEE
VDLTFEAARDVTVNDVNDIVAEAANGHMGAVLSYDPEPKVSVDFNHTTPSSIFAPDQTKV
EEEEEHHCCCCEECCHHHHHHHHCCCCEEEEEEECCCCCEEEEECCCCCCCEECCCCCEE
VGGRTVRVLAWYDNEWGFSARMADVAGAMGRLLH
ECCCEEEEEEEECCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TVTLGINGFGRIGRATLAYIAESARNDVQVVKINATGPVETSAHLLRYDSVHGRFPGEV
EEEEECCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHEEECCCCCCCCCEE
RVDGDTMDLGRGPMKMFSTYDPAQLDWDGCDVVLECTGKFNDGHKSAVHLERGAKKVLIS
EECCCCEECCCCCHHHHCCCCCCEECCCCCEEEEEECCCCCCCCCCEEEECCCCCEEEEE
APATNVDRTVVYGVNHREMRAEERMISNGSCTTNCLAPLVKVLNDAIGVERGIMTTIHSY
CCCCCCCCEEEEECCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHC
TGDQPTLDRRHDDLYRARAAAMAMIPTSTGAAKALAEVLPEMAGRLDGTALRVPTPNVSA
CCCCCCCCCHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHCCCCCCEEECCCCCCEE
VDLTFEAARDVTVNDVNDIVAEAANGHMGAVLSYDPEPKVSVDFNHTTPSSIFAPDQTKV
EEEEEHHCCCCEECCHHHHHHHHCCCCEEEEEEECCCCCEEEEECCCCCCCEECCCCCEE
VGGRTVRVLAWYDNEWGFSARMADVAGAMGRLLH
ECCCEEEEEEEECCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1939098 [H]