Click here to switch to the map view.

The map label for this gene is nuoC

Identifier: 89053662

GI number: 89053662

Start: 1135516

End: 1136139

Strand: Direct

Name: nuoC

Synonym: Jann_1171

Alternate gene names: 89053662

Gene position: 1135516-1136139 (Clockwise)

Preceding gene: 89053661

Following gene: 89053663

Centisome position: 26.3

GC content: 62.5

Gene sequence:

>624_bases
ATGAGTGATGCCCTGAAAGAACTGGCCGAATATCTGTCCGAGAAGCGCTCGGACGATGTGGTGTCCACCGATGTTAACGC
GATGGGAGAGTTGAGCGTCACCGTCGCGCCCGCGCAGATGGTGGGGTTCATCGAGTTCCTCAAGACCGACCGCACCTGCC
GGTTCTCGACCCTGATCGACATCACGGCGGTCGATTACCCCAGCCGGGACCGCCGGTTTGACGTGGTCTACCACTTCCTC
AGCATGTACCAGAACCACCGCGTGCGCGTGCGAGCCGCGATCCGGGAGGAGGACACGCTGCCGTCGATCAGTGGCGTGCA
TCCAGGCGCGGGCTGGTACGAGCGGGAGATCTACGACATGTTCGGGATCCTGTTCACCGGCCATGCGGACCTGCGCCGCC
TGCTGACGGATTACGGCTTCCGCGGCCACCCGCTGCGCAAGGATTTCCCCACCACCGGCTACACCGAAGTGCGCTATGAC
GAAGAGCTGAAACGTGTCGTCTATGAGCCGGTGAGCCTGGTCCAGGAATACCGCCAGTTTGATTTCATGTCCCCCTGGGA
AGGCGCGCAATACGTGCTGCCGGGCGATGAGAAGGCGGACGACAAAGCGGGGGAGACGGCATGA

Upstream 100 bases:

>100_bases
GCCCGGCTGCCCCCCCACGGCGGAGGCGCTTTTGTATGGTATCCTCCAGTTGCAGCGGAAGATCCGCCGCACCGGCACGA
TTGCAAGGTAAGGCGAGATC

Downstream 100 bases:

>100_bases
GCGCATCGCCGACCCTGAAGGGCGCCTGCCTCTGCGGGAAGTCCACGTTCACGGCGGAACGCGGGCCGGATGGAAGCGGC
GTCTGTCATTGCGACATGTG

Product: NADH dehydrogenase subunit C

Products: NA

Alternate protein names: NADH dehydrogenase I subunit C; NDH-1 subunit C

Number of amino acids: Translated: 207; Mature: 206

Protein sequence:

>207_residues
MSDALKELAEYLSEKRSDDVVSTDVNAMGELSVTVAPAQMVGFIEFLKTDRTCRFSTLIDITAVDYPSRDRRFDVVYHFL
SMYQNHRVRVRAAIREEDTLPSISGVHPGAGWYEREIYDMFGILFTGHADLRRLLTDYGFRGHPLRKDFPTTGYTEVRYD
EELKRVVYEPVSLVQEYRQFDFMSPWEGAQYVLPGDEKADDKAGETA

Sequences:

>Translated_207_residues
MSDALKELAEYLSEKRSDDVVSTDVNAMGELSVTVAPAQMVGFIEFLKTDRTCRFSTLIDITAVDYPSRDRRFDVVYHFL
SMYQNHRVRVRAAIREEDTLPSISGVHPGAGWYEREIYDMFGILFTGHADLRRLLTDYGFRGHPLRKDFPTTGYTEVRYD
EELKRVVYEPVSLVQEYRQFDFMSPWEGAQYVLPGDEKADDKAGETA
>Mature_206_residues
SDALKELAEYLSEKRSDDVVSTDVNAMGELSVTVAPAQMVGFIEFLKTDRTCRFSTLIDITAVDYPSRDRRFDVVYHFLS
MYQNHRVRVRAAIREEDTLPSISGVHPGAGWYEREIYDMFGILFTGHADLRRLLTDYGFRGHPLRKDFPTTGYTEVRYDE
ELKRVVYEPVSLVQEYRQFDFMSPWEGAQYVLPGDEKADDKAGETA

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0852

COG function: function code C; NADH:ubiquinone oxidoreductase 27 kD subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 30 kDa subunit family

Homologues:

Organism=Homo sapiens, GI4758788, Length=207, Percent_Identity=46.3768115942029, Blast_Score=194, Evalue=5e-50,
Organism=Escherichia coli, GI145693162, Length=174, Percent_Identity=29.8850574712644, Blast_Score=89, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71990788, Length=183, Percent_Identity=46.9945355191257, Blast_Score=181, Evalue=3e-46,
Organism=Caenorhabditis elegans, GI32563621, Length=183, Percent_Identity=46.9945355191257, Blast_Score=180, Evalue=4e-46,
Organism=Drosophila melanogaster, GI24656494, Length=183, Percent_Identity=48.6338797814208, Blast_Score=192, Evalue=2e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUOC_JANSC (Q28T74)

Other databases:

- EMBL:   CP000264
- RefSeq:   YP_509113.1
- ProteinModelPortal:   Q28T74
- SMR:   Q28T74
- STRING:   Q28T74
- GeneID:   3933615
- GenomeReviews:   CP000264_GR
- KEGG:   jan:Jann_1171
- eggNOG:   COG0852
- HOGENOM:   HBG727675
- OMA:   VVYEPVR
- ProtClustDB:   PRK06074
- BioCyc:   JSP290400:JANN_1171-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_01357
- InterPro:   IPR010218
- InterPro:   IPR001268
- InterPro:   IPR020396
- ProDom:   PD001581
- TIGRFAMs:   TIGR01961

Pfam domain/function: PF00329 Complex1_30kDa

EC number: =1.6.99.5

Molecular weight: Translated: 23860; Mature: 23729

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: PS00542 COMPLEX1_30K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDALKELAEYLSEKRSDDVVSTDVNAMGELSVTVAPAQMVGFIEFLKTDRTCRFSTLID
CCHHHHHHHHHHHHHCCCCCHHHCCCCCCCEEEEECHHHHHHHHHHHHCCCCEEHHHEEE
ITAVDYPSRDRRFDVVYHFLSMYQNHRVRVRAAIREEDTLPSISGVHPGAGWYEREIYDM
EEECCCCCCCCHHHHHHHHHHHHHCCCEEEEEEHHHCCCCCCCCCCCCCCCHHHHHHHHH
FGILFTGHADLRRLLTDYGFRGHPLRKDFPTTGYTEVRYDEELKRVVYEPVSLVQEYRQF
HHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
DFMSPWEGAQYVLPGDEKADDKAGETA
CCCCCCCCCEEECCCCCCCCCCCCCCC
>Mature Secondary Structure 
SDALKELAEYLSEKRSDDVVSTDVNAMGELSVTVAPAQMVGFIEFLKTDRTCRFSTLID
CHHHHHHHHHHHHHCCCCCHHHCCCCCCCEEEEECHHHHHHHHHHHHCCCCEEHHHEEE
ITAVDYPSRDRRFDVVYHFLSMYQNHRVRVRAAIREEDTLPSISGVHPGAGWYEREIYDM
EEECCCCCCCCHHHHHHHHHHHHHCCCEEEEEEHHHCCCCCCCCCCCCCCCHHHHHHHHH
FGILFTGHADLRRLLTDYGFRGHPLRKDFPTTGYTEVRYDEELKRVVYEPVSLVQEYRQF
HHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
DFMSPWEGAQYVLPGDEKADDKAGETA
CCCCCCCCCEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA