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The map label for this gene is atpA

Identifier: 89053538

GI number: 89053538

Start: 1001410

End: 1002948

Strand: Direct

Name: atpA

Synonym: Jann_1047

Alternate gene names: 89053538

Gene position: 1001410-1002948 (Clockwise)

Preceding gene: 89053537

Following gene: 89053539

Centisome position: 23.19

GC content: 61.47

Gene sequence:

>1539_bases
ATGGCTATCCAAGCAGCTGAGATTTCTCAGATCCTCAAAGACCAGATCAAAAGCTTCGGGCAGGATGCCCAGGTTGCGGA
AGTCGGTCGGGTTCTGTCTGTGGGCGACGGCATTGCCCGCGTCTATGGCCTCGACAACGTGCAGGCCGGTGAGATGGTCG
AATTCCCCGGCGGCATTCAGGGCATGGCCCTGAACCTTGAAGCCGATAACGTGGGTGTCGTGATCTTCGGCTCTGACCGG
GACATCAAGGAAGGCGACACGGTCAAGCGCACGAATTCCATCGTGGACGTGCCCGCGGGCAATGAGCTGCTGGGTCGTGT
CGTGGACGGTCTGGGCAACCCGCTGGACGGCAAGGGCCCGATCAACGCGTCCGAGCGTCGCGTGGCTGACAGCAAAGCGC
CGGGCATCATCCCGCGCAAATCGGTGCATGAGCCGATGGCGACGGGCCTGAAAGCCATCGACGCCATGATCCCCGTTGGC
CGTGGCCAGCGCGAGCTGATCATTGGCGACCGTCAGACCGGCAAAACCGCCGTGGCGCTGGACACGATCCTGAACCAGAA
GTCGTATAACGACGCCGCTGGCGACGATGAGAACAAGAAGCTCTATTGCATCTACGTTGCTGTGGGCCAGAAGCGCTCCA
CCGTGGCGCAGCTGGTGAAGAAGCTGGAAGAGACGGGCGCGATCGAATATTCGATCGTTGTGGCCGCTACCGCGTCGGAC
CCCGCACCGATGCAGTTCCTGGCCCCTTACGCCGCGACCGCCATGGCGGAGTTCTTCCGCGACAACGGGCGTCACGCGCT
GATCGTGTATGATGACCTGTCCAAGCAGGCCGTGTCCTACCGCCAGATGTCCCTGCTTCTGCGTCGCCCGCCGGGCCGTG
AAGCCTATCCCGGTGACGTGTTCTACCTGCACTCCCGCCTGCTGGAGCGGTCTTCAAAGCTGAACGAGGACAATGGCGGC
GGGTCCCTGACGGCGCTGCCCGTTATCGAAACCCAGGGCGGTGACGTGTCCGCGTTTATTCCGACCAACGTGATCTCCAT
CACCGACGGTCAGATCTTCCTTGAGACGGAATTGTTCTTCCAGGGCATCCGTCCGGCTGTGAACACCGGTCTGTCGGTGT
CGCGGGTTGGCTCTTCGGCTCAGACCAAGGCGATGTCCTCGGTCGCGGGCCCGGTGAAGCTGTCGCTGGCGCAGTATCGC
GAGATGGCGGCCTTCGCGCAGTTCGGCTCGGACCTTGACGCCTCCACCCAGCGTTTGCTGGCCCGTGGTGCACGCCTGAC
GGAGTTGATGAAGCAGCCCCAGTATTCGCCGCTGACCAACGCCGAGATTGTCACCATGATCTTCGCGGGCACCAACGGGT
TCCTGGATGAGATCAAGGTCTCTGATGTCGGGCGTTTTGAGGAGGGTTTGCTGAACCACATGCGGTCCAACAAGAAGGAC
GTGCTGGATTGGATCACCAATGAGGATCCCAAGATCAAGGGTGATGCCGCCGACAAACTGAAGGCTGCCATCGAAGAATT
CGCCGCCGATTTCGCGTAA

Upstream 100 bases:

>100_bases
TCATCGGCGGTCTTATTGTTAAAATTGGCTCGAAGATGATCGACACCTCGGTCCGCTCCAAGCTGAACGCACTCCAGAAT
ACCATGAAAGAGGTCGGATA

Downstream 100 bases:

>100_bases
GGGAGATTTGGCATGCCCAATCTCAAGGACCTAAAAAACCGGATCGCGTCGGTCAAATCGACCCGCAAGATCACCAAGGC
GATGCAAATGGTCGCCGCTG

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha; F-ATPase subunit alpha

Number of amino acids: Translated: 512; Mature: 511

Protein sequence:

>512_residues
MAIQAAEISQILKDQIKSFGQDAQVAEVGRVLSVGDGIARVYGLDNVQAGEMVEFPGGIQGMALNLEADNVGVVIFGSDR
DIKEGDTVKRTNSIVDVPAGNELLGRVVDGLGNPLDGKGPINASERRVADSKAPGIIPRKSVHEPMATGLKAIDAMIPVG
RGQRELIIGDRQTGKTAVALDTILNQKSYNDAAGDDENKKLYCIYVAVGQKRSTVAQLVKKLEETGAIEYSIVVAATASD
PAPMQFLAPYAATAMAEFFRDNGRHALIVYDDLSKQAVSYRQMSLLLRRPPGREAYPGDVFYLHSRLLERSSKLNEDNGG
GSLTALPVIETQGGDVSAFIPTNVISITDGQIFLETELFFQGIRPAVNTGLSVSRVGSSAQTKAMSSVAGPVKLSLAQYR
EMAAFAQFGSDLDASTQRLLARGARLTELMKQPQYSPLTNAEIVTMIFAGTNGFLDEIKVSDVGRFEEGLLNHMRSNKKD
VLDWITNEDPKIKGDAADKLKAAIEEFAADFA

Sequences:

>Translated_512_residues
MAIQAAEISQILKDQIKSFGQDAQVAEVGRVLSVGDGIARVYGLDNVQAGEMVEFPGGIQGMALNLEADNVGVVIFGSDR
DIKEGDTVKRTNSIVDVPAGNELLGRVVDGLGNPLDGKGPINASERRVADSKAPGIIPRKSVHEPMATGLKAIDAMIPVG
RGQRELIIGDRQTGKTAVALDTILNQKSYNDAAGDDENKKLYCIYVAVGQKRSTVAQLVKKLEETGAIEYSIVVAATASD
PAPMQFLAPYAATAMAEFFRDNGRHALIVYDDLSKQAVSYRQMSLLLRRPPGREAYPGDVFYLHSRLLERSSKLNEDNGG
GSLTALPVIETQGGDVSAFIPTNVISITDGQIFLETELFFQGIRPAVNTGLSVSRVGSSAQTKAMSSVAGPVKLSLAQYR
EMAAFAQFGSDLDASTQRLLARGARLTELMKQPQYSPLTNAEIVTMIFAGTNGFLDEIKVSDVGRFEEGLLNHMRSNKKD
VLDWITNEDPKIKGDAADKLKAAIEEFAADFA
>Mature_511_residues
AIQAAEISQILKDQIKSFGQDAQVAEVGRVLSVGDGIARVYGLDNVQAGEMVEFPGGIQGMALNLEADNVGVVIFGSDRD
IKEGDTVKRTNSIVDVPAGNELLGRVVDGLGNPLDGKGPINASERRVADSKAPGIIPRKSVHEPMATGLKAIDAMIPVGR
GQRELIIGDRQTGKTAVALDTILNQKSYNDAAGDDENKKLYCIYVAVGQKRSTVAQLVKKLEETGAIEYSIVVAATASDP
APMQFLAPYAATAMAEFFRDNGRHALIVYDDLSKQAVSYRQMSLLLRRPPGREAYPGDVFYLHSRLLERSSKLNEDNGGG
SLTALPVIETQGGDVSAFIPTNVISITDGQIFLETELFFQGIRPAVNTGLSVSRVGSSAQTKAMSSVAGPVKLSLAQYRE
MAAFAQFGSDLDASTQRLLARGARLTELMKQPQYSPLTNAEIVTMIFAGTNGFLDEIKVSDVGRFEEGLLNHMRSNKKDV
LDWITNEDPKIKGDAADKLKAAIEEFAADFA

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family

Homologues:

Organism=Homo sapiens, GI50345984, Length=506, Percent_Identity=67.9841897233202, Blast_Score=710, Evalue=0.0,
Organism=Homo sapiens, GI4757810, Length=506, Percent_Identity=67.9841897233202, Blast_Score=710, Evalue=0.0,
Organism=Homo sapiens, GI19913426, Length=358, Percent_Identity=27.9329608938547, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI19913428, Length=358, Percent_Identity=27.0949720670391, Blast_Score=113, Evalue=6e-25,
Organism=Homo sapiens, GI32189394, Length=322, Percent_Identity=22.6708074534161, Blast_Score=83, Evalue=8e-16,
Organism=Homo sapiens, GI19913424, Length=250, Percent_Identity=26, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI1790172, Length=520, Percent_Identity=52.3076923076923, Blast_Score=545, Evalue=1e-156,
Organism=Escherichia coli, GI1790170, Length=428, Percent_Identity=24.5327102803738, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI1788251, Length=279, Percent_Identity=29.0322580645161, Blast_Score=103, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI71988063, Length=506, Percent_Identity=67.5889328063241, Blast_Score=704, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71988080, Length=506, Percent_Identity=67.5889328063241, Blast_Score=703, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71988074, Length=506, Percent_Identity=62.8458498023715, Blast_Score=639, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17570191, Length=330, Percent_Identity=26.0606060606061, Blast_Score=114, Evalue=9e-26,
Organism=Caenorhabditis elegans, GI17510931, Length=303, Percent_Identity=27.3927392739274, Blast_Score=114, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI71988068, Length=76, Percent_Identity=57.8947368421053, Blast_Score=95, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI25144756, Length=359, Percent_Identity=22.5626740947075, Blast_Score=82, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17509265, Length=52, Percent_Identity=61.5384615384615, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17565854, Length=256, Percent_Identity=24.609375, Blast_Score=67, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6319370, Length=508, Percent_Identity=67.9133858267717, Blast_Score=717, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319603, Length=336, Percent_Identity=29.4642857142857, Blast_Score=127, Evalue=4e-30,
Organism=Saccharomyces cerevisiae, GI6322581, Length=381, Percent_Identity=23.3595800524934, Blast_Score=93, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24658560, Length=508, Percent_Identity=66.5354330708661, Blast_Score=702, Evalue=0.0,
Organism=Drosophila melanogaster, GI281361666, Length=334, Percent_Identity=27.8443113772455, Blast_Score=119, Evalue=6e-27,
Organism=Drosophila melanogaster, GI24646341, Length=334, Percent_Identity=27.8443113772455, Blast_Score=119, Evalue=6e-27,
Organism=Drosophila melanogaster, GI17136796, Length=334, Percent_Identity=27.8443113772455, Blast_Score=119, Evalue=6e-27,
Organism=Drosophila melanogaster, GI24638766, Length=430, Percent_Identity=22.7906976744186, Blast_Score=89, Evalue=7e-18,
Organism=Drosophila melanogaster, GI28574560, Length=374, Percent_Identity=23.2620320855615, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI20129479, Length=248, Percent_Identity=26.6129032258064, Blast_Score=66, Evalue=7e-11,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ATPA_JANSC (Q28TJ8)

Other databases:

- EMBL:   CP000264
- RefSeq:   YP_508989.1
- HSSP:   P19483
- ProteinModelPortal:   Q28TJ8
- SMR:   Q28TJ8
- STRING:   Q28TJ8
- GeneID:   3933491
- GenomeReviews:   CP000264_GR
- KEGG:   jan:Jann_1047
- eggNOG:   COG0056
- HOGENOM:   HBG565875
- OMA:   GSDRDIK
- PhylomeDB:   Q28TJ8
- ProtClustDB:   PRK09281
- BioCyc:   JSP290400:JANN_1047-MONOMER
- HAMAP:   MF_01346
- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100
- PANTHER:   PTHR15184:SF3
- TIGRFAMs:   TIGR00962

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N; SSF47917 ATPase_a/b_C; SSF50615 ATPase_a/b_N

EC number: =3.6.3.14

Molecular weight: Translated: 55027; Mature: 54896

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIQAAEISQILKDQIKSFGQDAQVAEVGRVLSVGDGIARVYGLDNVQAGEMVEFPGGIQ
CCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHCCCCCCCCCCEEECCCCCC
GMALNLEADNVGVVIFGSDRDIKEGDTVKRTNSIVDVPAGNELLGRVVDGLGNPLDGKGP
EEEEEEECCCEEEEEECCCCCCCCCCCEECCCCEEECCCCHHHHHHHHHHCCCCCCCCCC
INASERRVADSKAPGIIPRKSVHEPMATGLKAIDAMIPVGRGQRELIIGDRQTGKTAVAL
CCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHH
DTILNQKSYNDAAGDDENKKLYCIYVAVGQKRSTVAQLVKKLEETGAIEYSIVVAATASD
HHHHCCCCCCCCCCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHCCCEEEEEEEEEECCC
PAPMQFLAPYAATAMAEFFRDNGRHALIVYDDLSKQAVSYRQMSLLLRRPPGREAYPGDV
CCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCHH
FYLHSRLLERSSKLNEDNGGGSLTALPVIETQGGDVSAFIPTNVISITDGQIFLETELFF
HHHHHHHHHHHHCCCCCCCCCCEEEEEEEEECCCCEEEEECCCEEEEECCEEEEEHHHHH
QGIRPAVNTGLSVSRVGSSAQTKAMSSVAGPVKLSLAQYREMAAFAQFGSDLDASTQRLL
HCCCHHHHCCCCHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
ARGARLTELMKQPQYSPLTNAEIVTMIFAGTNGFLDEIKVSDVGRFEEGLLNHMRSNKKD
HCCHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCHHHCCHHCCCHHHHHHHHHHHCCHHH
VLDWITNEDPKIKGDAADKLKAAIEEFAADFA
HHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AIQAAEISQILKDQIKSFGQDAQVAEVGRVLSVGDGIARVYGLDNVQAGEMVEFPGGIQ
CCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHCCCCCCCCCCEEECCCCCC
GMALNLEADNVGVVIFGSDRDIKEGDTVKRTNSIVDVPAGNELLGRVVDGLGNPLDGKGP
EEEEEEECCCEEEEEECCCCCCCCCCCEECCCCEEECCCCHHHHHHHHHHCCCCCCCCCC
INASERRVADSKAPGIIPRKSVHEPMATGLKAIDAMIPVGRGQRELIIGDRQTGKTAVAL
CCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHH
DTILNQKSYNDAAGDDENKKLYCIYVAVGQKRSTVAQLVKKLEETGAIEYSIVVAATASD
HHHHCCCCCCCCCCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHCCCEEEEEEEEEECCC
PAPMQFLAPYAATAMAEFFRDNGRHALIVYDDLSKQAVSYRQMSLLLRRPPGREAYPGDV
CCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCHH
FYLHSRLLERSSKLNEDNGGGSLTALPVIETQGGDVSAFIPTNVISITDGQIFLETELFF
HHHHHHHHHHHHCCCCCCCCCCEEEEEEEEECCCCEEEEECCCEEEEECCEEEEEHHHHH
QGIRPAVNTGLSVSRVGSSAQTKAMSSVAGPVKLSLAQYREMAAFAQFGSDLDASTQRLL
HCCCHHHHCCCCHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
ARGARLTELMKQPQYSPLTNAEIVTMIFAGTNGFLDEIKVSDVGRFEEGLLNHMRSNKKD
HCCHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCHHHCCHHCCCHHHHHHHHHHHCCHHH
VLDWITNEDPKIKGDAADKLKAAIEEFAADFA
HHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA