Click here to switch to the map view.

The map label for this gene is atpH

Identifier: 89053537

GI number: 89053537

Start: 1000850

End: 1001410

Strand: Direct

Name: atpH

Synonym: Jann_1046

Alternate gene names: 89053537

Gene position: 1000850-1001410 (Clockwise)

Preceding gene: 89053536

Following gene: 89053538

Centisome position: 23.18

GC content: 60.07

Gene sequence:

>561_bases
GTGAGCGAACCTGCTTCAATCTCGACCGGCATCGCCGCGCGCTATGCGACCGCGATGTTTGAGCTGGCCGAGGAGGCCAA
AGCGCTTCCTGCCTTGGAAAAGGATGTCGATGCGTTGGACGCGGCCTTGTCCGAGAGCGCGGATTTGCGCGATCTGATCC
ACTCACCGATCTATGGCCGCGATGAGGCGTCCGCCGCAATCGGCGGTGTGGCCGACGCGATGAAGCTACAGGACATGACC
GGCAACACGCTGCGGCTGATGGCGTCCAAGCGCCGCCTGTTCGTGCTGCCTGCGCTGCTGTCCGAGCTGCGCGAGCGTAT
CGCCGACCACAAGGGCGAAGTAACGGCAGAGGTGACCTCGGCCAAGGCGCTGACGAAAACGCAACTGGACAAGCTGACCA
AGTCGCTCAAGGCGCAGGTGGGCAAGACCGTGACCGTAAAAGAGACCGTGGATGAGAACATCATCGGCGGTCTTATTGTT
AAAATTGGCTCGAAGATGATCGACACCTCGGTCCGCTCCAAGCTGAACGCACTCCAGAATACCATGAAAGAGGTCGGATA
A

Upstream 100 bases:

>100_bases
TTACCGGGGAACGGGCGGATGTATGCCGCCCTGACACGACCAGATACGGGATGGCACACAGCCTTTTCCGAGAGAATGTC
GTGCAACTGAAAGGGTTGAT

Downstream 100 bases:

>100_bases
TGGCTATCCAAGCAGCTGAGATTTCTCAGATCCTCAAAGACCAGATCAAAAGCTTCGGGCAGGATGCCCAGGTTGCGGAA
GTCGGTCGGGTTCTGTCTGT

Product: ATP synthase F1 subunit delta

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F(1) sector subunit delta; F-type ATPase subunit delta; F-ATPase subunit delta

Number of amino acids: Translated: 186; Mature: 185

Protein sequence:

>186_residues
MSEPASISTGIAARYATAMFELAEEAKALPALEKDVDALDAALSESADLRDLIHSPIYGRDEASAAIGGVADAMKLQDMT
GNTLRLMASKRRLFVLPALLSELRERIADHKGEVTAEVTSAKALTKTQLDKLTKSLKAQVGKTVTVKETVDENIIGGLIV
KIGSKMIDTSVRSKLNALQNTMKEVG

Sequences:

>Translated_186_residues
MSEPASISTGIAARYATAMFELAEEAKALPALEKDVDALDAALSESADLRDLIHSPIYGRDEASAAIGGVADAMKLQDMT
GNTLRLMASKRRLFVLPALLSELRERIADHKGEVTAEVTSAKALTKTQLDKLTKSLKAQVGKTVTVKETVDENIIGGLIV
KIGSKMIDTSVRSKLNALQNTMKEVG
>Mature_185_residues
SEPASISTGIAARYATAMFELAEEAKALPALEKDVDALDAALSESADLRDLIHSPIYGRDEASAAIGGVADAMKLQDMTG
NTLRLMASKRRLFVLPALLSELRERIADHKGEVTAEVTSAKALTKTQLDKLTKSLKAQVGKTVTVKETVDENIIGGLIVK
IGSKMIDTSVRSKLNALQNTMKEVG

Specific function: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction

COG id: COG0712

COG function: function code C; F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein)

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase delta chain family

Homologues:

Organism=Homo sapiens, GI4502303, Length=178, Percent_Identity=29.2134831460674, Blast_Score=80, Evalue=1e-15,
Organism=Escherichia coli, GI1790173, Length=173, Percent_Identity=25.4335260115607, Blast_Score=63, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71984710, Length=175, Percent_Identity=26.2857142857143, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI71984717, Length=176, Percent_Identity=26.7045454545455, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6320504, Length=180, Percent_Identity=23.8888888888889, Blast_Score=62, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24647054, Length=168, Percent_Identity=33.9285714285714, Blast_Score=95, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ATPD_JANSC (Q28TJ9)

Other databases:

- EMBL:   CP000264
- RefSeq:   YP_508988.1
- ProteinModelPortal:   Q28TJ9
- SMR:   Q28TJ9
- STRING:   Q28TJ9
- GeneID:   3933490
- GenomeReviews:   CP000264_GR
- KEGG:   jan:Jann_1046
- eggNOG:   COG0712
- HOGENOM:   HBG668108
- OMA:   FIAICGE
- PhylomeDB:   Q28TJ9
- BioCyc:   JSP290400:JANN_1046-MONOMER
- HAMAP:   MF_01416
- InterPro:   IPR000711
- InterPro:   IPR020781
- Gene3D:   G3DSA:1.10.520.20
- PANTHER:   PTHR11910
- PRINTS:   PR00125
- TIGRFAMs:   TIGR01145

Pfam domain/function: PF00213 OSCP; SSF47928 ATPsynt_OSCP

EC number: 3.6.3.14

Molecular weight: Translated: 19868; Mature: 19737

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: PS00389 ATPASE_DELTA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEPASISTGIAARYATAMFELAEEAKALPALEKDVDALDAALSESADLRDLIHSPIYGR
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHCCCCCCC
DEASAAIGGVADAMKLQDMTGNTLRLMASKRRLFVLPALLSELRERIADHKGEVTAEVTS
CHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
AKALTKTQLDKLTKSLKAQVGKTVTVKETVDENIIGGLIVKIGSKMIDTSVRSKLNALQN
HHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TMKEVG
HHHHCC
>Mature Secondary Structure 
SEPASISTGIAARYATAMFELAEEAKALPALEKDVDALDAALSESADLRDLIHSPIYGR
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHCCCCCCC
DEASAAIGGVADAMKLQDMTGNTLRLMASKRRLFVLPALLSELRERIADHKGEVTAEVTS
CHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
AKALTKTQLDKLTKSLKAQVGKTVTVKETVDENIIGGLIVKIGSKMIDTSVRSKLNALQN
HHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TMKEVG
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA