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The map label for this gene is ruvC

Identifier: 89053455

GI number: 89053455

Start: 921748

End: 922323

Strand: Direct

Name: ruvC

Synonym: Jann_0964

Alternate gene names: 89053455

Gene position: 921748-922323 (Clockwise)

Preceding gene: 89053453

Following gene: 89053456

Centisome position: 21.35

GC content: 65.45

Gene sequence:

>576_bases
ATGTTCGCGTTTCGTGCTAACCGCTCCAAAAGGCCGGGCAACAGGCGGCCAGACATCAGGCGGCGGGCAGTCATGCGTAT
TATTGGAATCGATCCGGGGCTCAGATCCCTTGGGTGGGGGGTGATTGAGGCCTCCGGCGGACGTCTCAGCCATGTTGCCA
ATGGCCAATGCAAGACCGAGGGCCGGGATGTCCCCTTGCGTCTGCTGTCGCTTCACACACAACTCAGCGCGATTGTCGCC
CGCTACGCCCCGGATGCGGCGGCGGTGGAACAGACCTTTGTGAACCGGGACGGGGCCGGGACCCTGAAGCTGGGTCAGGC
CCGCGGCATCGCCGTTTTGGTGCCTGCGCAGGCGGGGCTCGACGTGGGCGAATACGCCCCCAATGCGGTCAAGAAGGCGG
TTGTCGGCGTCGGACACGCGGACAAGACACAGGTGGAGCATATGGTGAAGCTGCAATTGCCCGGATGTGCCCCCGTGGGA
CCGGACGCCGCCGATGCGCTGGCGATTGCGATCTGTCACTCGTTCCATGTGGCCACCGCCGGACGTCTGGCCGCCGCCAT
CGGAGCGGCGCGATGA

Upstream 100 bases:

>100_bases
AAACGTGATTTTTTGTCGCCTTTGTCGGTGTGGCGGGGCCCGTGTCGAAAATGGATCATGAGATGTCGAAACTGTCCGTC
GAGTGCAGAGGCGCTTGGCG

Downstream 100 bases:

>100_bases
TTGGCAAGCTGACCGGACGTCTGGATTACAAGGGCAGCGACCATGCGCTGATCGACGTCGGCGGCGTGGGGTATGTCGTC
CATTGTTCGGACCGGACGCT

Product: Holliday junction resolvase

Products: NA

Alternate protein names: Holliday junction nuclease ruvC; Holliday junction resolvase ruvC [H]

Number of amino acids: Translated: 191; Mature: 191

Protein sequence:

>191_residues
MFAFRANRSKRPGNRRPDIRRRAVMRIIGIDPGLRSLGWGVIEASGGRLSHVANGQCKTEGRDVPLRLLSLHTQLSAIVA
RYAPDAAAVEQTFVNRDGAGTLKLGQARGIAVLVPAQAGLDVGEYAPNAVKKAVVGVGHADKTQVEHMVKLQLPGCAPVG
PDAADALAIAICHSFHVATAGRLAAAIGAAR

Sequences:

>Translated_191_residues
MFAFRANRSKRPGNRRPDIRRRAVMRIIGIDPGLRSLGWGVIEASGGRLSHVANGQCKTEGRDVPLRLLSLHTQLSAIVA
RYAPDAAAVEQTFVNRDGAGTLKLGQARGIAVLVPAQAGLDVGEYAPNAVKKAVVGVGHADKTQVEHMVKLQLPGCAPVG
PDAADALAIAICHSFHVATAGRLAAAIGAAR
>Mature_191_residues
MFAFRANRSKRPGNRRPDIRRRAVMRIIGIDPGLRSLGWGVIEASGGRLSHVANGQCKTEGRDVPLRLLSLHTQLSAIVA
RYAPDAAAVEQTFVNRDGAGTLKLGQARGIAVLVPAQAGLDVGEYAPNAVKKAVVGVGHADKTQVEHMVKLQLPGCAPVG
PDAADALAIAICHSFHVATAGRLAAAIGAAR

Specific function: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leav

COG id: COG0817

COG function: function code L; Holliday junction resolvasome, endonuclease subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvC family [H]

Homologues:

Organism=Escherichia coli, GI1788170, Length=130, Percent_Identity=43.8461538461538, Blast_Score=114, Evalue=3e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012337
- InterPro:   IPR020563
- InterPro:   IPR002176 [H]

Pfam domain/function: PF02075 RuvC [H]

EC number: =3.1.22.4 [H]

Molecular weight: Translated: 19960; Mature: 19960

Theoretical pI: Translated: 11.07; Mature: 11.07

Prosite motif: PS01321 RUVC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFAFRANRSKRPGNRRPDIRRRAVMRIIGIDPGLRSLGWGVIEASGGRLSHVANGQCKTE
CCEECCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHCCEEEECCCCEEEEECCCCCCCC
GRDVPLRLLSLHTQLSAIVARYAPDAAAVEQTFVNRDGAGTLKLGQARGIAVLVPAQAGL
CCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEECCCCCEEEEEECCCCC
DVGEYAPNAVKKAVVGVGHADKTQVEHMVKLQLPGCAPVGPDAADALAIAICHSFHVATA
CHHHCCHHHHHHHHHCCCCCCHHHHHHEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHH
GRLAAAIGAAR
HHHHHHHHCCC
>Mature Secondary Structure
MFAFRANRSKRPGNRRPDIRRRAVMRIIGIDPGLRSLGWGVIEASGGRLSHVANGQCKTE
CCEECCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHCCEEEECCCCEEEEECCCCCCCC
GRDVPLRLLSLHTQLSAIVARYAPDAAAVEQTFVNRDGAGTLKLGQARGIAVLVPAQAGL
CCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEECCCCCEEEEEECCCCC
DVGEYAPNAVKKAVVGVGHADKTQVEHMVKLQLPGCAPVGPDAADALAIAICHSFHVATA
CHHHCCHHHHHHHHHCCCCCCHHHHHHEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHH
GRLAAAIGAAR
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA