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The map label for this gene is ruvA

Identifier: 89053456

GI number: 89053456

Start: 922320

End: 922991

Strand: Direct

Name: ruvA

Synonym: Jann_0965

Alternate gene names: 89053456

Gene position: 922320-922991 (Clockwise)

Preceding gene: 89053455

Following gene: 89053457

Centisome position: 21.36

GC content: 66.96

Gene sequence:

>672_bases
ATGATTGGCAAGCTGACCGGACGTCTGGATTACAAGGGCAGCGACCATGCGCTGATCGACGTCGGCGGCGTGGGGTATGT
CGTCCATTGTTCGGACCGGACGCTGGCGGCGTTGCCAGCGCGCGGAGAAGTGGTAGCGCTTTATACAGATCTGCTGGTGC
GCGAGGATCTGTTGCAACTCTTCGGGTTCCTCAGCCCCTATGAGAAGGAATGGCACCGGCTGCTGACCTCGGTCCAGGGG
GTGGGGGCCAAGGCCTCCATGGCGATCCTGGGCACGCTGGGAGTGGAGGGGGCGGCCCGCGCGATCACGTTGGGCGATGC
CACGGCGATCAAGGCGGCACCGGGCGTTGGACCCAAGCTGGCGCAACGGGTGGTGATGGAGTTGAAGGACAAAGCGCCCG
CGGTGATGGCGATGGGCGGGACGCTGGATGACGCGATGGACGATGTCGTTGACGATATGCCCGGTGAGAGCGCGGCGCCC
GCGCCCGCGCCACAGCCCCGCGCGCCGAAACGGCCGGCATCCAACGCCCAGGCGGAGGCGCTTTCCGCGCTGCAAAATCT
GGGCTACGGCCCGTCAGATGCGGCCCAGGCCGTGGCGCAAGCAGCAGAGAGCGCGTCGAACACACCGGAGTTGATCCGCG
CGGCCCTGCGGCTTCTGGCCCCGAAAGAGTGA

Upstream 100 bases:

>100_bases
CCGTGGGACCGGACGCCGCCGATGCGCTGGCGATTGCGATCTGTCACTCGTTCCATGTGGCCACCGCCGGACGTCTGGCC
GCCGCCATCGGAGCGGCGCG

Downstream 100 bases:

>100_bases
CCGGGATGCGTGCGCGTGTCGCCCGTGTGGTCAATGGCCGGTGGGGTTGCCATAAGGAGGCGACATGACGGATTCTGACC
CAACCCTGCGCCCTGATCGC

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 223; Mature: 223

Protein sequence:

>223_residues
MIGKLTGRLDYKGSDHALIDVGGVGYVVHCSDRTLAALPARGEVVALYTDLLVREDLLQLFGFLSPYEKEWHRLLTSVQG
VGAKASMAILGTLGVEGAARAITLGDATAIKAAPGVGPKLAQRVVMELKDKAPAVMAMGGTLDDAMDDVVDDMPGESAAP
APAPQPRAPKRPASNAQAEALSALQNLGYGPSDAAQAVAQAAESASNTPELIRAALRLLAPKE

Sequences:

>Translated_223_residues
MIGKLTGRLDYKGSDHALIDVGGVGYVVHCSDRTLAALPARGEVVALYTDLLVREDLLQLFGFLSPYEKEWHRLLTSVQG
VGAKASMAILGTLGVEGAARAITLGDATAIKAAPGVGPKLAQRVVMELKDKAPAVMAMGGTLDDAMDDVVDDMPGESAAP
APAPQPRAPKRPASNAQAEALSALQNLGYGPSDAAQAVAQAAESASNTPELIRAALRLLAPKE
>Mature_223_residues
MIGKLTGRLDYKGSDHALIDVGGVGYVVHCSDRTLAALPARGEVVALYTDLLVREDLLQLFGFLSPYEKEWHRLLTSVQG
VGAKASMAILGTLGVEGAARAITLGDATAIKAAPGVGPKLAQRVVMELKDKAPAVMAMGGTLDDAMDDVVDDMPGESAAP
APAPQPRAPKRPASNAQAEALSALQNLGYGPSDAAQAVAQAAESASNTPELIRAALRLLAPKE

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family

Homologues:

Organism=Escherichia coli, GI1788168, Length=217, Percent_Identity=33.6405529953917, Blast_Score=109, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVA_JANSC (Q28TT0)

Other databases:

- EMBL:   CP000264
- RefSeq:   YP_508907.1
- ProteinModelPortal:   Q28TT0
- SMR:   Q28TT0
- STRING:   Q28TT0
- GeneID:   3933409
- GenomeReviews:   CP000264_GR
- KEGG:   jan:Jann_0965
- eggNOG:   COG0632
- HOGENOM:   HBG635309
- OMA:   AQRIVLD
- ProtClustDB:   PRK00116
- BioCyc:   JSP290400:JANN_0965-MONOMER
- HAMAP:   MF_00031
- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994
- Gene3D:   G3DSA:2.40.50.140
- SMART:   SM00278
- TIGRFAMs:   TIGR00084

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N; SSF50249 Nucleic_acid_OB; SSF47781 RuvA_2_like; SSF46929 RuvA_C-like

EC number: =3.6.4.12

Molecular weight: Translated: 23047; Mature: 23047

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGKLTGRLDYKGSDHALIDVGGVGYVVHCSDRTLAALPARGEVVALYTDLLVREDLLQL
CCCCCCCCCCCCCCCCEEEEECCCEEEEEECCCCEEECCCCCCEEHHHHHHHHHHHHHHH
FGFLSPYEKEWHRLLTSVQGVGAKASMAILGTLGVEGAARAITLGDATAIKAAPGVGPKL
HHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEEEECCCHHHCCCCCCCHHH
AQRVVMELKDKAPAVMAMGGTLDDAMDDVVDDMPGESAAPAPAPQPRAPKRPASNAQAEA
HHHHHHHHHHCCCEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHH
LSALQNLGYGPSDAAQAVAQAAESASNTPELIRAALRLLAPKE
HHHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure
MIGKLTGRLDYKGSDHALIDVGGVGYVVHCSDRTLAALPARGEVVALYTDLLVREDLLQL
CCCCCCCCCCCCCCCCEEEEECCCEEEEEECCCCEEECCCCCCEEHHHHHHHHHHHHHHH
FGFLSPYEKEWHRLLTSVQGVGAKASMAILGTLGVEGAARAITLGDATAIKAAPGVGPKL
HHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEEEECCCHHHCCCCCCCHHH
AQRVVMELKDKAPAVMAMGGTLDDAMDDVVDDMPGESAAPAPAPQPRAPKRPASNAQAEA
HHHHHHHHHHCCCEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHH
LSALQNLGYGPSDAAQAVAQAAESASNTPELIRAALRLLAPKE
HHHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA