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The map label for this gene is hss [H]

Identifier: 89053447

GI number: 89053447

Start: 915177

End: 916598

Strand: Direct

Name: hss [H]

Synonym: Jann_0956

Alternate gene names: 89053447

Gene position: 915177-916598 (Clockwise)

Preceding gene: 89053446

Following gene: 89053449

Centisome position: 21.19

GC content: 62.87

Gene sequence:

>1422_bases
ATGGCCACGACGCATCCGATTTACGCAAAGATCGACGGACCCATCGTTATGATCGGCTTCGGGTCAATCGGCAAAGGCAC
CTGGCCCCTGATCAAGCGGCATTTCGACTATGATCCCGCCCGTTTCACCGTGATTGAACCCGACATCCATCAGCATGATT
TTCTGCGCGAGCACGGTCTGTCCTTCACGGATGCGGCGCTGACGCCGGACAATTACCGCGAGGTTCTTGGCACGCTTCTG
GAGCCGGGGAAGGGGTTCTGCGTGAACCTGTCGGTCGATACCTCGTCGCTGGACTTGATGCGCTTTTGCCGTGAGATCGA
GGTGCCCTACATCGACACCGTGGTGGAGCCGTGGGCGGGCTATTACTTCGGGACGACCGACAATGCGGCCCGGACGAATT
ACGCGCTTCGCCAAGCGGTGCGGGACGAGAAAGCGGCCAATCCGGGCGGATCCACGGCGGTGTCGTGCTGCGGCGCGAAC
CCCGGCATGGTCAGCTGGTTCGTGAAGGAGGGTCTTCTGGCTTTGGCCAAGGACACGGGCCATGACGTCGACGCCCCGAA
GGATCGCGAGGGGTGGGCCAGGCTGATGCAATCGCTCGGTGTCAAAGGCGTCCATATCGCGGAGCGGGATACACAGGTGC
GTCTTGCCCCGCGCCCGCGCGATGTGTTCGTGAACACCTGGTCCGTTGAAGGCTTCATCTCCGAAGGGTTCCAGCCCGCC
GAGCTTGGCTGGGGCACGCACGAGCCATGGTTCCCCGAGACCGGCCACCGGCAGGACGAAGGCTGCAAGGCCGCGATCTG
GCTGGAGCGTCCCGGCGCCGTGACGCGTGTCCATACCTGGTGCCCGACACCGGGTCCGCAATTCGGCTATCTGGTCACTC
ATAACGAGGCGGTGTCGATCAGCGATTATTACACCGTCGGCGAGGGGCACGAGCCGGAGTTCCGCCCGACCTGTCACTAC
GCCTACCATCCCTGCGATGATGCCGTCCTTTCGCTCCATGAGATGTTCGGGGGCGGGGTGACCCAGACGGCGCACCACAT
TCTGGGCGAGGATGAGATCGTGGAGGGCATCGACGAGTTGGGCGTGCTTCTCTACGGCCACGAAAAGAATGCGCTGTGGT
TTGGCTCGCGGCTGTCGAATGAGGAGGCGAAGGGCCTCGCGCCGTATCAGAACGCGACCGGCCTGCAGGTCACCAGCGCG
GTTCTGGCGGGGATGGTCTGGGCGTTGGAAAACCCTGGCGCAGGCATCGTGGAGAGCGATGAAATGGACCATGCCCGCTG
TCTGGAAGTACAGCGCCCGTACCTTGGCCCGGTGGAGGCCCATTATACCGACTGGACACCGCTGGAAAACCGGTGGGAGC
TGTTTGACGAGAACATGGACCGCGAGGAACCCTGGGCGTTCAGAAACGTTCTGGCGACGTGA

Upstream 100 bases:

>100_bases
AGTCAAGGTCCGTGGGCGCGTTGACCGCGGGGGCCAAGGAAGCCGGTTCCTTTTCTGCGGCCTGCGCCCTATGACACGCC
CAGATAAAAGGGGAGAGATC

Downstream 100 bases:

>100_bases
TTTCAGGAGGGTTGCAAGGTTGAGAAATCTCGTAACCTCATGATTTCAATGACTAATAACGATATTGCTTTTCGGGGCGT
GTGACCGGGACACAGCCTGT

Product: homospermidine synthase

Products: NA

Alternate protein names: HSS [H]

Number of amino acids: Translated: 473; Mature: 472

Protein sequence:

>473_residues
MATTHPIYAKIDGPIVMIGFGSIGKGTWPLIKRHFDYDPARFTVIEPDIHQHDFLREHGLSFTDAALTPDNYREVLGTLL
EPGKGFCVNLSVDTSSLDLMRFCREIEVPYIDTVVEPWAGYYFGTTDNAARTNYALRQAVRDEKAANPGGSTAVSCCGAN
PGMVSWFVKEGLLALAKDTGHDVDAPKDREGWARLMQSLGVKGVHIAERDTQVRLAPRPRDVFVNTWSVEGFISEGFQPA
ELGWGTHEPWFPETGHRQDEGCKAAIWLERPGAVTRVHTWCPTPGPQFGYLVTHNEAVSISDYYTVGEGHEPEFRPTCHY
AYHPCDDAVLSLHEMFGGGVTQTAHHILGEDEIVEGIDELGVLLYGHEKNALWFGSRLSNEEAKGLAPYQNATGLQVTSA
VLAGMVWALENPGAGIVESDEMDHARCLEVQRPYLGPVEAHYTDWTPLENRWELFDENMDREEPWAFRNVLAT

Sequences:

>Translated_473_residues
MATTHPIYAKIDGPIVMIGFGSIGKGTWPLIKRHFDYDPARFTVIEPDIHQHDFLREHGLSFTDAALTPDNYREVLGTLL
EPGKGFCVNLSVDTSSLDLMRFCREIEVPYIDTVVEPWAGYYFGTTDNAARTNYALRQAVRDEKAANPGGSTAVSCCGAN
PGMVSWFVKEGLLALAKDTGHDVDAPKDREGWARLMQSLGVKGVHIAERDTQVRLAPRPRDVFVNTWSVEGFISEGFQPA
ELGWGTHEPWFPETGHRQDEGCKAAIWLERPGAVTRVHTWCPTPGPQFGYLVTHNEAVSISDYYTVGEGHEPEFRPTCHY
AYHPCDDAVLSLHEMFGGGVTQTAHHILGEDEIVEGIDELGVLLYGHEKNALWFGSRLSNEEAKGLAPYQNATGLQVTSA
VLAGMVWALENPGAGIVESDEMDHARCLEVQRPYLGPVEAHYTDWTPLENRWELFDENMDREEPWAFRNVLAT
>Mature_472_residues
ATTHPIYAKIDGPIVMIGFGSIGKGTWPLIKRHFDYDPARFTVIEPDIHQHDFLREHGLSFTDAALTPDNYREVLGTLLE
PGKGFCVNLSVDTSSLDLMRFCREIEVPYIDTVVEPWAGYYFGTTDNAARTNYALRQAVRDEKAANPGGSTAVSCCGANP
GMVSWFVKEGLLALAKDTGHDVDAPKDREGWARLMQSLGVKGVHIAERDTQVRLAPRPRDVFVNTWSVEGFISEGFQPAE
LGWGTHEPWFPETGHRQDEGCKAAIWLERPGAVTRVHTWCPTPGPQFGYLVTHNEAVSISDYYTVGEGHEPEFRPTCHYA
YHPCDDAVLSLHEMFGGGVTQTAHHILGEDEIVEGIDELGVLLYGHEKNALWFGSRLSNEEAKGLAPYQNATGLQVTSAV
LAGMVWALENPGAGIVESDEMDHARCLEVQRPYLGPVEAHYTDWTPLENRWELFDENMDREEPWAFRNVLAT

Specific function: Involved in the NAD(+)-dependent synthesis of the polyamine homospermidine from putrescine [H]

COG id: COG5310

COG function: function code Q; Homospermidine synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023181
- InterPro:   IPR016040
- InterPro:   IPR005097 [H]

Pfam domain/function: PF03435 Saccharop_dh [H]

EC number: =2.5.1.44 [H]

Molecular weight: Translated: 52669; Mature: 52538

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATTHPIYAKIDGPIVMIGFGSIGKGTWPLIKRHFDYDPARFTVIEPDIHQHDFLREHGL
CCCCCCEEEEECCCEEEEECCCCCCCHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHCC
SFTDAALTPDNYREVLGTLLEPGKGFCVNLSVDTSSLDLMRFCREIEVPYIDTVVEPWAG
CCCCCCCCCHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHCCCCHHHHHHHCCCC
YYFGTTDNAARTNYALRQAVRDEKAANPGGSTAVSCCGANPGMVSWFVKEGLLALAKDTG
EEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCHHHHHHHHCHHEEHHCCC
HDVDAPKDREGWARLMQSLGVKGVHIAERDTQVRLAPRPRDVFVNTWSVEGFISEGFQPA
CCCCCCCCHHHHHHHHHHCCCCCEEEECCCCEEEECCCCCEEEEEEEEECHHHHCCCCCH
ELGWGTHEPWFPETGHRQDEGCKAAIWLERPGAVTRVHTWCPTPGPQFGYLVTHNEAVSI
HCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCEEEEEEECCCCCCCEEEEEECCCEEEE
SDYYTVGEGHEPEFRPTCHYAYHPCDDAVLSLHEMFGGGVTQTAHHILGEDEIVEGIDEL
CCEEECCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHC
GVLLYGHEKNALWFGSRLSNEEAKGLAPYQNATGLQVTSAVLAGMVWALENPGAGIVESD
CEEEEECCCCCEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHEECCCCCCCEECC
EMDHARCLEVQRPYLGPVEAHYTDWTPLENRWELFDENMDREEPWAFRNVLAT
CCCHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHCC
>Mature Secondary Structure 
ATTHPIYAKIDGPIVMIGFGSIGKGTWPLIKRHFDYDPARFTVIEPDIHQHDFLREHGL
CCCCCEEEEECCCEEEEECCCCCCCHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHCC
SFTDAALTPDNYREVLGTLLEPGKGFCVNLSVDTSSLDLMRFCREIEVPYIDTVVEPWAG
CCCCCCCCCHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHCCCCHHHHHHHCCCC
YYFGTTDNAARTNYALRQAVRDEKAANPGGSTAVSCCGANPGMVSWFVKEGLLALAKDTG
EEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCHHHHHHHHCHHEEHHCCC
HDVDAPKDREGWARLMQSLGVKGVHIAERDTQVRLAPRPRDVFVNTWSVEGFISEGFQPA
CCCCCCCCHHHHHHHHHHCCCCCEEEECCCCEEEECCCCCEEEEEEEEECHHHHCCCCCH
ELGWGTHEPWFPETGHRQDEGCKAAIWLERPGAVTRVHTWCPTPGPQFGYLVTHNEAVSI
HCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCEEEEEEECCCCCCCEEEEEECCCEEEE
SDYYTVGEGHEPEFRPTCHYAYHPCDDAVLSLHEMFGGGVTQTAHHILGEDEIVEGIDEL
CCEEECCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHC
GVLLYGHEKNALWFGSRLSNEEAKGLAPYQNATGLQVTSAVLAGMVWALENPGAGIVESD
CEEEEECCCCCEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHEECCCCCCCEECC
EMDHARCLEVQRPYLGPVEAHYTDWTPLENRWELFDENMDREEPWAFRNVLAT
CCCHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]