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The map label for this gene is hscB [H]

Identifier: 88658431

GI number: 88658431

Start: 638768

End: 639211

Strand: Direct

Name: hscB [H]

Synonym: ECH_0632

Alternate gene names: 88658431

Gene position: 638768-639211 (Clockwise)

Preceding gene: 88657844

Following gene: 88658120

Centisome position: 54.31

GC content: 25.23

Gene sequence:

>444_bases
ATGTATAAAGACTATTTTTCATTATTCAAGTTAAAACCACAATTCTCTATAAACATGCAAACATTAGAACAGAATTACAT
AGCATTACAAAGCAATTACCATCCAGATTTATTCTCTTTAAAATTAGAGAAAAAATTGGCATTAGATACTATAACAGAAA
TAAACAAAGCATATCAAACTTTAAAATCTTCTATAAAAAGAGCAGAATACTTATTAGAAATCAAGGGAATTACTACTAAT
AAAAATGATATTAATATACTAGAAGAAATATTTAACATACAAGAATCAAACAGCATTGATCTTCAAAATCAAATTTTATT
ATCCACTAAAGCTATGGAAAATGCTTTTTCTGTAGAAGATTTTAACGAAGCCGCAAAACAGGTAGTAAGATTAAAATATC
TTAAAAAAATTCAAGAGGATAGGAGTATTACTTCATGCAATTAG

Upstream 100 bases:

>100_bases
AATGGAACAGAAATGGACCATGTAGAAAACAAAATATCTTCAGGTTTTACATTTAATAATCCTAATGAGAAAGGAAGATG
TGGATGTGGGGAGAGTTTCT

Downstream 100 bases:

>100_bases
TAAACATAACAGAACCAGAAACTAGTGAAAAAGTATTAGCATTTGGAATAGATTTAGGAACTACTAATTCTTTAATTTCT
ATGATTGATAGTGAAGGCAA

Product: co-chaperone Hsc20

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 147; Mature: 147

Protein sequence:

>147_residues
MYKDYFSLFKLKPQFSINMQTLEQNYIALQSNYHPDLFSLKLEKKLALDTITEINKAYQTLKSSIKRAEYLLEIKGITTN
KNDINILEEIFNIQESNSIDLQNQILLSTKAMENAFSVEDFNEAAKQVVRLKYLKKIQEDRSITSCN

Sequences:

>Translated_147_residues
MYKDYFSLFKLKPQFSINMQTLEQNYIALQSNYHPDLFSLKLEKKLALDTITEINKAYQTLKSSIKRAEYLLEIKGITTN
KNDINILEEIFNIQESNSIDLQNQILLSTKAMENAFSVEDFNEAAKQVVRLKYLKKIQEDRSITSCN
>Mature_147_residues
MYKDYFSLFKLKPQFSINMQTLEQNYIALQSNYHPDLFSLKLEKKLALDTITEINKAYQTLKSSIKRAEYLLEIKGITTN
KNDINILEEIFNIQESNSIDLQNQILLSTKAMENAFSVEDFNEAAKQVVRLKYLKKIQEDRSITSCN

Specific function: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward hscA [H]

COG id: COG1076

COG function: function code O; DnaJ-domain-containing proteins 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 J domain [H]

Homologues:

Organism=Escherichia coli, GI1788876, Length=76, Percent_Identity=39.4736842105263, Blast_Score=61, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001623
- InterPro:   IPR009073
- InterPro:   IPR004640
- InterPro:   IPR015609 [H]

Pfam domain/function: PF00226 DnaJ; PF07743 HSCB_C [H]

EC number: NA

Molecular weight: Translated: 17169; Mature: 17169

Theoretical pI: Translated: 7.35; Mature: 7.35

Prosite motif: PS50076 DNAJ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYKDYFSLFKLKPQFSINMQTLEQNYIALQSNYHPDLFSLKLEKKLALDTITEINKAYQT
CCCHHHHHHHCCCCCCCHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LKSSIKRAEYLLEIKGITTNKNDINILEEIFNIQESNSIDLQNQILLSTKAMENAFSVED
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCHHH
FNEAAKQVVRLKYLKKIQEDRSITSCN
HHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MYKDYFSLFKLKPQFSINMQTLEQNYIALQSNYHPDLFSLKLEKKLALDTITEINKAYQT
CCCHHHHHHHCCCCCCCHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LKSSIKRAEYLLEIKGITTNKNDINILEEIFNIQESNSIDLQNQILLSTKAMENAFSVED
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCHHH
FNEAAKQVVRLKYLKKIQEDRSITSCN
HHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA