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The map label for this gene is cutA1 [H]

Identifier: 88658405

GI number: 88658405

Start: 762535

End: 762855

Strand: Direct

Name: cutA1 [H]

Synonym: ECH_0756

Alternate gene names: 88658405

Gene position: 762535-762855 (Clockwise)

Preceding gene: 88657797

Following gene: 88657985

Centisome position: 64.83

GC content: 32.09

Gene sequence:

>321_bases
ATGAAAAACATCTCTTTACTCTATACTACTACTCCTACTTACGAAGATGCATACCGCATAAGCAATATTCTGTTAGAAAA
CAAGCTAATAGCATGTGCTAATATATTTAGTAACATTACATCAGTATATGTCTGGGAAGATGAAATACATAACAACACTG
AATGTGCTATCATATTAAAAACGACAAATGACTTAGTCCAACATGCTACAAATAAAATACAAGCAATCCACCCATATGAT
ACTCCTGCAATCATCACAATAGATCCAACCAATGCAAATGACAAATTTATACAATGGGTAAATGACTGTACTGCTTTATA
A

Upstream 100 bases:

>100_bases
ATAACCTTTATTACATACAAGCAATATTTAGCTATAAAACTTGATCTAAACTCGTTTTTACAATAAAAACCATAATATCT
AAACTACAATAAAATTATAT

Downstream 100 bases:

>100_bases
GCTTGCTATCACATAAAAAAGAACAACACACAATAAAAATACTAGAGCTCTAAACAGATATATACTTGCTACCATAATAT
TTCAATCATACAACTGTCTA

Product: divalent ion tolerance protein CutA1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 106; Mature: 106

Protein sequence:

>106_residues
MKNISLLYTTTPTYEDAYRISNILLENKLIACANIFSNITSVYVWEDEIHNNTECAIILKTTNDLVQHATNKIQAIHPYD
TPAIITIDPTNANDKFIQWVNDCTAL

Sequences:

>Translated_106_residues
MKNISLLYTTTPTYEDAYRISNILLENKLIACANIFSNITSVYVWEDEIHNNTECAIILKTTNDLVQHATNKIQAIHPYD
TPAIITIDPTNANDKFIQWVNDCTAL
>Mature_106_residues
MKNISLLYTTTPTYEDAYRISNILLENKLIACANIFSNITSVYVWEDEIHNNTECAIILKTTNDLVQHATNKIQAIHPYD
TPAIITIDPTNANDKFIQWVNDCTAL

Specific function: Involved in resistance toward heavy metals [H]

COG id: COG1324

COG function: function code P; Uncharacterized protein involved in tolerance to divalent cations

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CutA family [H]

Homologues:

Organism=Homo sapiens, GI62526026, Length=102, Percent_Identity=30.3921568627451, Blast_Score=75, Evalue=8e-15,
Organism=Homo sapiens, GI62526024, Length=102, Percent_Identity=30.3921568627451, Blast_Score=75, Evalue=1e-14,
Organism=Homo sapiens, GI62526022, Length=102, Percent_Identity=30.3921568627451, Blast_Score=75, Evalue=1e-14,
Organism=Homo sapiens, GI7706244, Length=102, Percent_Identity=30.3921568627451, Blast_Score=75, Evalue=1e-14,
Organism=Homo sapiens, GI62198241, Length=102, Percent_Identity=30.3921568627451, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1790579, Length=92, Percent_Identity=31.5217391304348, Blast_Score=62, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI32565476, Length=99, Percent_Identity=31.3131313131313, Blast_Score=69, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24641937, Length=96, Percent_Identity=32.2916666666667, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004323
- InterPro:   IPR011322 [H]

Pfam domain/function: PF03091 CutA1 [H]

EC number: NA

Molecular weight: Translated: 12045; Mature: 12045

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNISLLYTTTPTYEDAYRISNILLENKLIACANIFSNITSVYVWEDEIHNNTECAIILK
CCCEEEEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHCCEEEEEECHHCCCCCEEEEEEE
TTNDLVQHATNKIQAIHPYDTPAIITIDPTNANDKFIQWVNDCTAL
CCHHHHHHHHCCEEEECCCCCCEEEEEECCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MKNISLLYTTTPTYEDAYRISNILLENKLIACANIFSNITSVYVWEDEIHNNTECAIILK
CCCEEEEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHCCEEEEEECHHCCCCCEEEEEEE
TTNDLVQHATNKIQAIHPYDTPAIITIDPTNANDKFIQWVNDCTAL
CCHHHHHHHHCCEEEECCCCCCEEEEEECCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9679194 [H]