Click here to switch to the map view.

The map label for this gene is ctaC [H]

Identifier: 88658348

GI number: 88658348

Start: 1028187

End: 1028960

Strand: Direct

Name: ctaC [H]

Synonym: ECH_1002

Alternate gene names: 88658348

Gene position: 1028187-1028960 (Clockwise)

Preceding gene: 88657747

Following gene: 88658568

Centisome position: 87.41

GC content: 33.33

Gene sequence:

>774_bases
ATGTTAAGATTTCTGTTTTTTTTTCTCTTTATGTTTAGTTCTCTTGATCTATTTGCAGCACCTGTGCAGTGGCAAATGGG
GTTTCAAGCTCCTGCAACAGAAATAATGGAGTCCATCATAAGGTCCCATAACTTTGTTATGTTTGTTATGTCAGGAGTAG
TAGTTGTTGTTTTCTCCATCATGATCTACGTTCTTATAAGGTTTAGAAAAAAACCAGAAGATAAAATTATCTTCAATACT
AAGAATTCTCATAATGTAGTTTTAGAAATACTGTGGACGTTAATTCCTTTAATAATTGTAGGATTTTTAACCATAAGTAA
TGTTAAACTAATTAGACAAGAACAGAAGATTCCTAAGGTAGAAATGACATTAAAAGCAATTGGTTACCAATGGTATTGGG
GATATGTGTATCCAGATTATAAAAATTTCACTTTCGATAGTTACATGAAAACAACAGATAATTTGGAAGCTCAAGATTTA
CGCCTACTTGAAGTAGACAACAGGGTAGTAGTACCTATTAACACAAACATTCTGCTACAAGTAACAAGCGCAGACGTAAT
ACATAGTTGGACAGTACCAGCTTTGGGAGTAAAAATCGATGCAGTACCAGGCAGATTAAATGAAGCATGGTTTAATATAA
AAACTCCAGGAGTATACTATGGACAGTGTTCAGAACTTTGTGGAAGACTGCATGGATTTATGCCAATAGTAATAGTTGCT
GTTGAAAAAGAACAATTTGACGAATGGATACAAAAAAAGACACTTGAATTATAG

Upstream 100 bases:

>100_bases
ATAATTAATTTTATAAGTCTATACTTCTTAAAAAGTAGTATAAAATTATTGCATTTTGGTCCTCAAAATGATAAAGATGA
ACGGTTAATAGTGTAACATT

Downstream 100 bases:

>100_bases
AGGCATGCATGAGTAGTGAACATACACCACAGGGGATAAGACGTTGGTTGTTTTCAACAAATCACAAAGATATAGGTACA
TTATATATCATTTTTTCCAT

Product: cytochrome c oxidase, subunit II

Products: NA

Alternate protein names: Cytochrome aa3 subunit 2; Cytochrome c oxidase polypeptide II [H]

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MLRFLFFFLFMFSSLDLFAAPVQWQMGFQAPATEIMESIIRSHNFVMFVMSGVVVVVFSIMIYVLIRFRKKPEDKIIFNT
KNSHNVVLEILWTLIPLIIVGFLTISNVKLIRQEQKIPKVEMTLKAIGYQWYWGYVYPDYKNFTFDSYMKTTDNLEAQDL
RLLEVDNRVVVPINTNILLQVTSADVIHSWTVPALGVKIDAVPGRLNEAWFNIKTPGVYYGQCSELCGRLHGFMPIVIVA
VEKEQFDEWIQKKTLEL

Sequences:

>Translated_257_residues
MLRFLFFFLFMFSSLDLFAAPVQWQMGFQAPATEIMESIIRSHNFVMFVMSGVVVVVFSIMIYVLIRFRKKPEDKIIFNT
KNSHNVVLEILWTLIPLIIVGFLTISNVKLIRQEQKIPKVEMTLKAIGYQWYWGYVYPDYKNFTFDSYMKTTDNLEAQDL
RLLEVDNRVVVPINTNILLQVTSADVIHSWTVPALGVKIDAVPGRLNEAWFNIKTPGVYYGQCSELCGRLHGFMPIVIVA
VEKEQFDEWIQKKTLEL
>Mature_257_residues
MLRFLFFFLFMFSSLDLFAAPVQWQMGFQAPATEIMESIIRSHNFVMFVMSGVVVVVFSIMIYVLIRFRKKPEDKIIFNT
KNSHNVVLEILWTLIPLIIVGFLTISNVKLIRQEQKIPKVEMTLKAIGYQWYWGYVYPDYKNFTFDSYMKTTDNLEAQDL
RLLEVDNRVVVPINTNILLQVTSADVIHSWTVPALGVKIDAVPGRLNEAWFNIKTPGVYYGQCSELCGRLHGFMPIVIVA
VEKEQFDEWIQKKTLEL

Specific function: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) [H]

COG id: COG1622

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 2

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome c oxidase subunit 2 family [H]

Homologues:

Organism=Homo sapiens, GI251831110, Length=223, Percent_Identity=39.4618834080717, Blast_Score=180, Evalue=1e-45,
Organism=Saccharomyces cerevisiae, GI6226540, Length=238, Percent_Identity=37.8151260504202, Blast_Score=169, Evalue=3e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001505
- InterPro:   IPR008972
- InterPro:   IPR014222
- InterPro:   IPR015964
- InterPro:   IPR002429
- InterPro:   IPR011759
- InterPro:   IPR005728 [H]

Pfam domain/function: PF00116 COX2; PF02790 COX2_TM [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 29877; Mature: 29877

Theoretical pI: Translated: 7.56; Mature: 7.56

Prosite motif: PS00078 COX2 ; PS50999 COX2_TM ; PS50857 COX2_CUA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRFLFFFLFMFSSLDLFAAPVQWQMGFQAPATEIMESIIRSHNFVMFVMSGVVVVVFSI
CHHHHHHHHHHHCCCHHHCCCCCEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
MIYVLIRFRKKPEDKIIFNTKNSHNVVLEILWTLIPLIIVGFLTISNVKLIRQEQKIPKV
HHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
EMTLKAIGYQWYWGYVYPDYKNFTFDSYMKTTDNLEAQDLRLLEVDNRVVVPINTNILLQ
HHHHHHHCEEEEEEEEECCCCCCCHHHHHHCCCCCCHHCEEEEEECCEEEEEECCCEEEE
VTSADVIHSWTVPALGVKIDAVPGRLNEAWFNIKTPGVYYGQCSELCGRLHGFMPIVIVA
EECCCCEECCCCCCCCEEEECCCCCCCCCEEEECCCCEEECCHHHHHHHHHCCCEEEEEE
VEKEQFDEWIQKKTLEL
ECHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLRFLFFFLFMFSSLDLFAAPVQWQMGFQAPATEIMESIIRSHNFVMFVMSGVVVVVFSI
CHHHHHHHHHHHCCCHHHCCCCCEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
MIYVLIRFRKKPEDKIIFNTKNSHNVVLEILWTLIPLIIVGFLTISNVKLIRQEQKIPKV
HHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
EMTLKAIGYQWYWGYVYPDYKNFTFDSYMKTTDNLEAQDLRLLEVDNRVVVPINTNILLQ
HHHHHHHCEEEEEEEEECCCCCCCHHHHHHCCCCCCHHCEEEEEECCEEEEEECCCEEEE
VTSADVIHSWTVPALGVKIDAVPGRLNEAWFNIKTPGVYYGQCSELCGRLHGFMPIVIVA
EECCCCEECCCCCCCCEEEECCCCCCCCCEEEECCCCEEECCHHHHHHHHHCCCEEEEEE
VEKEQFDEWIQKKTLEL
ECHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]