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The map label for this gene is sucC

Identifier: 88658279

GI number: 88658279

Start: 1001342

End: 1002505

Strand: Direct

Name: sucC

Synonym: ECH_0979

Alternate gene names: 88658279

Gene position: 1001342-1002505 (Clockwise)

Preceding gene: 88658072

Following gene: 88657940

Centisome position: 85.13

GC content: 34.02

Gene sequence:

>1164_bases
ATGAATATTCATGAGTATCAGGCAAAGCATATACTGAGCAAGTTTGGTGTAAACGTTCCGAAAGGGGTTGTAGTACATTC
ATTAGGCGAAGTTGATGGTGCTCTCAGTCAGTTAAATTCAAAGGTAGTCGTTGTAAAAGCTCAAATCCATGCTGGTGGTA
GAGGAAAAGCTGGAGGAGTTGTAGTATCTCGTACATTAGATGAAACCAAAACGTCTATAAAGAATATGTTAGGATCAACT
CTGATTACTCATCAGACCTCAAAAGATGGACAGAAAGTAAGAAAAGTATATTTAGAAGAAGGATGCAACATCAAGAAAGA
ATATTATATAAGTGCCATTGTAAATCGTAAACAAGGTCAGGTAAGTATAATATTTTCAACTGAAGGTGGTGTTGACATAG
AAGAAGTAGCTGCAACTTCTCCAGAAAAAGTTATTGTATGCAACATCAACCCAGTATTTGGATTCCAAGGTTTTCATGGA
CGCAATTTATGCTTTGACAGTAATTTAAGTTTAGATCAAACAAGAAAAATTTCTGATATAGCTGGGAAAATATATAAAGC
TGTGTTAAGCACTGATGCTAACCAGATAGAAATTAATCCTCTAGTAGAAACATCATCAGGGGAATTCATTGCTCTTGATG
CAAAAATAAACTTCGATGACAATGCACTATATCGTCATCCTGATATTCAAGAATTACGTGACTATGATGAAGAGATCAAA
GAAGAAATAGAAGCTTCAAAACATGGTTTAAGCTATATAAAGATGGATGGTAATATTGGATGTATGGTAAATGGTGCAGG
CCTTGCTATGGCAACTATGGACATTATAAAATATTACGGTGCTGAACCTGCAAATTTCTTAGATGTAGGTGGAGGAGCAA
GTCAAAAAACTGTTACTGAAGCATTCAAGATTATTCTTGCAGATGATAAGGTTAATGGGATACTAGTTAACATATTTGGT
GGTATAATGCGTTGTGATATAATTGCCAACGGTATTATTGCTGCCATACAAGAAATTGGTATAAATGTTCCACTAGTTGT
AAGGTTATCTGGAACAAATTTTGAATTAGGAAAAAAGTTACTAGATGATTCAAATCTAAATATTATTACAGCAAACGATT
TAAGTGAAGCAGCATACAATATAGTTAATATAGTAAGAAAATAG

Upstream 100 bases:

>100_bases
TTCTCAAGCTGATAATAGCACTAGTGAATGAGCATAAATTTATACTATAGCTCATCTATATTTTTAATCAGTAGTCAGAG
TTCAAGTAAGGTGTATTAAT

Downstream 100 bases:

>100_bases
AGGCGATATGTCCGTTTTAGTAAATAGCAACACAAAAGTTATATGCCAGGGATTTACTGGTGCTCATGGTACATTTCATT
CAGAACAAGCTATTGCTTAT

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MNIHEYQAKHILSKFGVNVPKGVVVHSLGEVDGALSQLNSKVVVVKAQIHAGGRGKAGGVVVSRTLDETKTSIKNMLGST
LITHQTSKDGQKVRKVYLEEGCNIKKEYYISAIVNRKQGQVSIIFSTEGGVDIEEVAATSPEKVIVCNINPVFGFQGFHG
RNLCFDSNLSLDQTRKISDIAGKIYKAVLSTDANQIEINPLVETSSGEFIALDAKINFDDNALYRHPDIQELRDYDEEIK
EEIEASKHGLSYIKMDGNIGCMVNGAGLAMATMDIIKYYGAEPANFLDVGGGASQKTVTEAFKIILADDKVNGILVNIFG
GIMRCDIIANGIIAAIQEIGINVPLVVRLSGTNFELGKKLLDDSNLNIITANDLSEAAYNIVNIVRK

Sequences:

>Translated_387_residues
MNIHEYQAKHILSKFGVNVPKGVVVHSLGEVDGALSQLNSKVVVVKAQIHAGGRGKAGGVVVSRTLDETKTSIKNMLGST
LITHQTSKDGQKVRKVYLEEGCNIKKEYYISAIVNRKQGQVSIIFSTEGGVDIEEVAATSPEKVIVCNINPVFGFQGFHG
RNLCFDSNLSLDQTRKISDIAGKIYKAVLSTDANQIEINPLVETSSGEFIALDAKINFDDNALYRHPDIQELRDYDEEIK
EEIEASKHGLSYIKMDGNIGCMVNGAGLAMATMDIIKYYGAEPANFLDVGGGASQKTVTEAFKIILADDKVNGILVNIFG
GIMRCDIIANGIIAAIQEIGINVPLVVRLSGTNFELGKKLLDDSNLNIITANDLSEAAYNIVNIVRK
>Mature_387_residues
MNIHEYQAKHILSKFGVNVPKGVVVHSLGEVDGALSQLNSKVVVVKAQIHAGGRGKAGGVVVSRTLDETKTSIKNMLGST
LITHQTSKDGQKVRKVYLEEGCNIKKEYYISAIVNRKQGQVSIIFSTEGGVDIEEVAATSPEKVIVCNINPVFGFQGFHG
RNLCFDSNLSLDQTRKISDIAGKIYKAVLSTDANQIEINPLVETSSGEFIALDAKINFDDNALYRHPDIQELRDYDEEIK
EEIEASKHGLSYIKMDGNIGCMVNGAGLAMATMDIIKYYGAEPANFLDVGGGASQKTVTEAFKIILADDKVNGILVNIFG
GIMRCDIIANGIIAAIQEIGINVPLVVRLSGTNFELGKKLLDDSNLNIITANDLSEAAYNIVNIVRK

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain

Homologues:

Organism=Homo sapiens, GI11321583, Length=392, Percent_Identity=45.6632653061224, Blast_Score=322, Evalue=3e-88,
Organism=Homo sapiens, GI157779135, Length=383, Percent_Identity=44.1253263707572, Blast_Score=305, Evalue=5e-83,
Organism=Homo sapiens, GI294862256, Length=362, Percent_Identity=44.475138121547, Blast_Score=290, Evalue=2e-78,
Organism=Escherichia coli, GI1786948, Length=385, Percent_Identity=49.0909090909091, Blast_Score=364, Evalue=1e-102,
Organism=Caenorhabditis elegans, GI17539378, Length=400, Percent_Identity=42, Blast_Score=317, Evalue=5e-87,
Organism=Caenorhabditis elegans, GI17567829, Length=392, Percent_Identity=43.3673469387755, Blast_Score=306, Evalue=1e-83,
Organism=Saccharomyces cerevisiae, GI6321683, Length=396, Percent_Identity=37.6262626262626, Blast_Score=286, Evalue=3e-78,
Organism=Drosophila melanogaster, GI21356231, Length=401, Percent_Identity=43.8902743142145, Blast_Score=306, Evalue=1e-83,
Organism=Drosophila melanogaster, GI161078106, Length=385, Percent_Identity=42.0779220779221, Blast_Score=294, Evalue=8e-80,
Organism=Drosophila melanogaster, GI24645208, Length=385, Percent_Identity=42.0779220779221, Blast_Score=294, Evalue=8e-80,
Organism=Drosophila melanogaster, GI281361397, Length=386, Percent_Identity=42.4870466321244, Blast_Score=293, Evalue=9e-80,
Organism=Drosophila melanogaster, GI281361395, Length=386, Percent_Identity=42.4870466321244, Blast_Score=293, Evalue=9e-80,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SUCC_EHRCR (Q2GFL7)

Other databases:

- EMBL:   CP000236
- RefSeq:   YP_507766.1
- HSSP:   P53590
- ProteinModelPortal:   Q2GFL7
- SMR:   Q2GFL7
- STRING:   Q2GFL7
- GeneID:   3927958
- GenomeReviews:   CP000236_GR
- KEGG:   ech:ECH_0979
- TIGR:   ECH_0979
- eggNOG:   COG0045
- HOGENOM:   HBG315432
- OMA:   IFINILG
- PhylomeDB:   Q2GFL7
- ProtClustDB:   PRK00696
- BioCyc:   ECHA205920:ECH_0979-MONOMER
- HAMAP:   MF_00558
- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102
- Gene3D:   G3DSA:3.30.1490.20
- Gene3D:   G3DSA:3.30.470.20
- Gene3D:   G3DSA:3.40.50.261
- PANTHER:   PTHR11815
- TIGRFAMs:   TIGR01016

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA; SSF52210 CoA_ligase

EC number: =6.2.1.5

Molecular weight: Translated: 41946; Mature: 41946

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: PS50975 ATP_GRASP; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIHEYQAKHILSKFGVNVPKGVVVHSLGEVDGALSQLNSKVVVVKAQIHAGGRGKAGGV
CCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCCE
VVSRTLDETKTSIKNMLGSTLITHQTSKDGQKVRKVYLEEGCNIKKEYYISAIVNRKQGQ
EEEECHHHHHHHHHHHHCCHHEEECCCCHHHHHHHHHHHCCCCCCHHHEEEEEECCCCCE
VSIIFSTEGGVDIEEVAATSPEKVIVCNINPVFGFQGFHGRNLCFDSNLSLDQTRKISDI
EEEEEECCCCCCHHHHHCCCCCEEEEEECCCCCCCCCCCCCCEEECCCCCHHHHHHHHHH
AGKIYKAVLSTDANQIEINPLVETSSGEFIALDAKINFDDNALYRHPDIQELRDYDEEIK
HHHHHHHHHHCCCCEEEEEEEEECCCCCEEEEEEEECCCCCCEECCCCHHHHHHHHHHHH
EEIEASKHGLSYIKMDGNIGCMVNGAGLAMATMDIIKYYGAEPANFLDVGGGASQKTVTE
HHHHHHHCCCEEEEECCCEEEEEECCCHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHH
AFKIILADDKVNGILVNIFGGIMRCDIIANGIIAAIQEIGINVPLVVRLSGTNFELGKKL
HHEEEEECCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHH
LDDSNLNIITANDLSEAAYNIVNIVRK
HCCCCCEEEECCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MNIHEYQAKHILSKFGVNVPKGVVVHSLGEVDGALSQLNSKVVVVKAQIHAGGRGKAGGV
CCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCCE
VVSRTLDETKTSIKNMLGSTLITHQTSKDGQKVRKVYLEEGCNIKKEYYISAIVNRKQGQ
EEEECHHHHHHHHHHHHCCHHEEECCCCHHHHHHHHHHHCCCCCCHHHEEEEEECCCCCE
VSIIFSTEGGVDIEEVAATSPEKVIVCNINPVFGFQGFHGRNLCFDSNLSLDQTRKISDI
EEEEEECCCCCCHHHHHCCCCCEEEEEECCCCCCCCCCCCCCEEECCCCCHHHHHHHHHH
AGKIYKAVLSTDANQIEINPLVETSSGEFIALDAKINFDDNALYRHPDIQELRDYDEEIK
HHHHHHHHHHCCCCEEEEEEEEECCCCCEEEEEEEECCCCCCEECCCCHHHHHHHHHHHH
EEIEASKHGLSYIKMDGNIGCMVNGAGLAMATMDIIKYYGAEPANFLDVGGGASQKTVTE
HHHHHHHCCCEEEEECCCEEEEEECCCHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHH
AFKIILADDKVNGILVNIFGGIMRCDIIANGIIAAIQEIGINVPLVVRLSGTNFELGKKL
HHEEEEECCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHH
LDDSNLNIITANDLSEAAYNIVNIVRK
HCCCCCEEEECCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA