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The map label for this gene is ribH [H]

Identifier: 88657824

GI number: 88657824

Start: 798300

End: 798749

Strand: Direct

Name: ribH [H]

Synonym: ECH_0783

Alternate gene names: 88657824

Gene position: 798300-798749 (Clockwise)

Preceding gene: 88658314

Following gene: 88658441

Centisome position: 67.87

GC content: 32.0

Gene sequence:

>450_bases
ATGTCAAATGATCATATCAATATACTAATAGTAGTATCACAATTTTATTCTGATGTAGCAGATCTTTTATTAAATGGTGC
AGTAGATCAATTAAAAAAATATTCTAAACCTGTAAAATATGATATAGTATACGTTCCAGGATCTTTTGAAATACCCGCGG
CTATAGTGTTTGCAATAATGAGTGACAGACATCACTATGATGGATACATTGCTTTAGGTTGTGTTATTAAAGGACAAACA
GATCATTATTATTATGTATGTAAGGGGGTAACAACAGCTCTAAGTGAAATTGCAACTCACCATGCTGTTCCTATGGGTTT
TGGAGTAATTACAGCTGGAAGTTTAGAAATAGCAATGGCAAGAGCAGATATCAATAAAAGAAATGTTGGTGGAAATGCTG
CCAAAGCAGCTTTAACGATGATTGAATTACATAACAAATTTTTAAGTTAA

Upstream 100 bases:

>100_bases
TATGTAGCAATTCGATTACAATAGTGCAACAATTAATAATAAAGCATTATGTAACTAAAAAATTCAATTTTTACAAAACC
GTGCAACAGGAGGATTAATT

Downstream 100 bases:

>100_bases
AATTATGAAAGATAATATATGCCACACACATTTGTGGCATTCAAAAAAAACAACAACTAGGTTCCTCGCTATACAAGGAA
CCTATTCTATGATATTTAAT

Product: 6,7-dimethyl-8-ribityllumazine synthase

Products: NA

Alternate protein names: DMRL synthase; Lumazine synthase; Riboflavin synthase beta chain [H]

Number of amino acids: Translated: 149; Mature: 148

Protein sequence:

>149_residues
MSNDHINILIVVSQFYSDVADLLLNGAVDQLKKYSKPVKYDIVYVPGSFEIPAAIVFAIMSDRHHYDGYIALGCVIKGQT
DHYYYVCKGVTTALSEIATHHAVPMGFGVITAGSLEIAMARADINKRNVGGNAAKAALTMIELHNKFLS

Sequences:

>Translated_149_residues
MSNDHINILIVVSQFYSDVADLLLNGAVDQLKKYSKPVKYDIVYVPGSFEIPAAIVFAIMSDRHHYDGYIALGCVIKGQT
DHYYYVCKGVTTALSEIATHHAVPMGFGVITAGSLEIAMARADINKRNVGGNAAKAALTMIELHNKFLS
>Mature_148_residues
SNDHINILIVVSQFYSDVADLLLNGAVDQLKKYSKPVKYDIVYVPGSFEIPAAIVFAIMSDRHHYDGYIALGCVIKGQTD
HYYYVCKGVTTALSEIATHHAVPMGFGVITAGSLEIAMARADINKRNVGGNAAKAALTMIELHNKFLS

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The beta subunit catalyzes

COG id: COG0054

COG function: function code H; Riboflavin synthase beta-chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DMRL synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786617, Length=138, Percent_Identity=36.9565217391304, Blast_Score=95, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002180 [H]

Pfam domain/function: PF00885 DMRL_synthase [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 16234; Mature: 16103

Theoretical pI: Translated: 7.21; Mature: 7.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNDHINILIVVSQFYSDVADLLLNGAVDQLKKYSKPVKYDIVYVPGSFEIPAAIVFAIM
CCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHH
SDRHHYDGYIALGCVIKGQTDHYYYVCKGVTTALSEIATHHAVPMGFGVITAGSLEIAMA
HCCCCCCCEEEEEEEEECCCCCEEEEECCHHHHHHHHHHHCCCCCCCCEEECCCEEEEEE
RADINKRNVGGNAAKAALTMIELHNKFLS
ECCCCCCCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SNDHINILIVVSQFYSDVADLLLNGAVDQLKKYSKPVKYDIVYVPGSFEIPAAIVFAIM
CCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHH
SDRHHYDGYIALGCVIKGQTDHYYYVCKGVTTALSEIATHHAVPMGFGVITAGSLEIAMA
HCCCCCCCEEEEEEEEECCCCCEEEEECCHHHHHHHHHHHCCCCCCCCEEECCCEEEEEE
RADINKRNVGGNAAKAALTMIELHNKFLS
ECCCCCCCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA