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The map label for this gene is ppiD [H]

Identifier: 88657679

GI number: 88657679

Start: 740907

End: 742811

Strand: Direct

Name: ppiD [H]

Synonym: ECH_0731

Alternate gene names: 88657679

Gene position: 740907-742811 (Clockwise)

Preceding gene: 88658465

Following gene: 88658172

Centisome position: 62.99

GC content: 28.87

Gene sequence:

>1905_bases
ATGCGTATACACATGAAATCTAAAGCTTTTTTCGTAAAACCGCTGCTTATAATTTTAGTATGTTCTTTAGTCTTTATAGC
ATTTGGAGCATCTTTTTTCCCTGGTAGCTTTAACAACGAAAAATATATTGCAAAAATCGGACACGAAAAATTATCATTAC
AAGATTATACAAGTGCATATCATGATGAATTAAGGTATATACAACATGTGCTCAATCGTCCATTAACAGAGGAGCAAATT
GCGCAATTTAATATTAAACTTTCTACATTAAACAAGCTGATTGAAAACAAAGTCTTAACAAAATTTGCTGATTCACTAAA
TCTCAAAGTAGGAGAAAACAGCATATTAAATCACATAAAAAGCATAAAGTTCTTTCAAGACGAAAATGGAAACTTTGATA
AAACAAAATTTAACATTGGATTGTCAAATGCAGGGCTTACAGAAAGGTTATACATAAACAAATTAGAAAAAGCATTTCCT
ATAACCATGCTCATGAGTTGTTTATTCAGCGGAACACAAAACACTTACACTCAATATCATCCAGAGTTAATAAAGCAAAT
TTTACAAAATCTGCATCAAGCACGTACTATAGATGTTATAGAAATATCCCCTACAACCAATGACATTTCTGTCCCAAATA
TTGATGAGCTAAAAAAATTGTATGAAGAAAAACGCAAAAGTGGAAATCTAACATTTCCAGAAAGTAGAGTTATAGAATAT
GTAACAATTGACCATGAAAACTTTATTAACCAAACAAATGTAACACAAGAAGAAATAGATAATAAAATAAAAGCTGACGA
ATTAGATGAACAAAGAGATATATTTAATTTAGTATTTAGTACTAAAAATGAAGCTGAAACTGCTTTAAAAGCATTAAATG
AAGGTACAGACTTTGACAGTATAGTTACAAATATTGCTCACACCACTCTAGATAATATAACATTGTTCAACATTGTAAAG
AATACACTTCCTAATGATATAAGAAATCAAGTATTTTCCCTAAAAGAAGGAGAAATAAGTCCTATATTACACAGCATGTT
TGGATGGCATATAATAAAAATAAAAAATATTCACAAAATCTCCACTAAAGATCTAGCAGAATTAAGTGAAAAAATTGCCC
AAAATATTAAAAAGAAAAAAGCTACTGACCTTTTATACACAGAAATCCAGGCTATAAATGATAAGATTAATAACGGTACA
TCTATTCAAGAAATAGCAGAATCATATAACTTATCTATAAAAACAGCAAATGTTGATATCTCAGGCAAAGATCCATCTGA
TAACAAAATTAAAATGTTAGAAACAAATTATGATGCAATCGTTTTAGCTGCATTTTCAGCTCAATTAAACAAACCTTCCA
ACTTCACAGACAATGACGGTTATTTTTTTAGTGTCAATGTTACTAAGATAGAACCATCAAGAGAAAAAACTTTTGATGAA
AGTAAGGAACAATTAGTATACGAATGGCAGCATGATTTAAAAGCTCAAAAATTATCTAAGCTAACACAAGAGGTTGTCAT
AAAACTTAAATCAGGTATAGACATAAATAATATTGATGGTGTATTACTAAAGCCGAACCAAGTAGTTTATAGGAACAGCG
TTGCTGCAGTAGATAATCCTGGCCAAAATTATCCTAGTGATCTTATAAATGAAATTTTTCATCTTAAAAAAGGAGAAATC
AGTAAAAATTATCAACATGATATCAGTTCTTCAGAACAAAAAATGCTAATAGCAATATTGAAAGATATAAAAAATGCTGA
TCAAGTAAGCAACGTAGATTTCAAAAACATTCAGGAAAAAATTGCAAATGATAACTTAGAATCGCTAAAAAATCAACTAA
TAGCACATCTAATAAAAAAATATTCCGTTAAAATTAACCAAAATTTAATTGATAATGTGCGGTAG

Upstream 100 bases:

>100_bases
ATATCTGTAAATTTTTTTATAAAAAGTGCCTTTATGATTTCCAATGAAAATATTTGCATGAGATTTTTTGTCTGATATAT
TAAACACGTTTAATACTTAT

Downstream 100 bases:

>100_bases
TCTGATCTCTCACAATAAAATGCAGCTTAAGTTTGCATAAATTAATTTAGAATAATAAGCAATTACAGTCAATTAAAAGG
AACCATTACCTATACATATA

Product: rotamase family protein

Products: NA

Alternate protein names: PPIase D; Rotamase D [H]

Number of amino acids: Translated: 634; Mature: 634

Protein sequence:

>634_residues
MRIHMKSKAFFVKPLLIILVCSLVFIAFGASFFPGSFNNEKYIAKIGHEKLSLQDYTSAYHDELRYIQHVLNRPLTEEQI
AQFNIKLSTLNKLIENKVLTKFADSLNLKVGENSILNHIKSIKFFQDENGNFDKTKFNIGLSNAGLTERLYINKLEKAFP
ITMLMSCLFSGTQNTYTQYHPELIKQILQNLHQARTIDVIEISPTTNDISVPNIDELKKLYEEKRKSGNLTFPESRVIEY
VTIDHENFINQTNVTQEEIDNKIKADELDEQRDIFNLVFSTKNEAETALKALNEGTDFDSIVTNIAHTTLDNITLFNIVK
NTLPNDIRNQVFSLKEGEISPILHSMFGWHIIKIKNIHKISTKDLAELSEKIAQNIKKKKATDLLYTEIQAINDKINNGT
SIQEIAESYNLSIKTANVDISGKDPSDNKIKMLETNYDAIVLAAFSAQLNKPSNFTDNDGYFFSVNVTKIEPSREKTFDE
SKEQLVYEWQHDLKAQKLSKLTQEVVIKLKSGIDINNIDGVLLKPNQVVYRNSVAAVDNPGQNYPSDLINEIFHLKKGEI
SKNYQHDISSSEQKMLIAILKDIKNADQVSNVDFKNIQEKIANDNLESLKNQLIAHLIKKYSVKINQNLIDNVR

Sequences:

>Translated_634_residues
MRIHMKSKAFFVKPLLIILVCSLVFIAFGASFFPGSFNNEKYIAKIGHEKLSLQDYTSAYHDELRYIQHVLNRPLTEEQI
AQFNIKLSTLNKLIENKVLTKFADSLNLKVGENSILNHIKSIKFFQDENGNFDKTKFNIGLSNAGLTERLYINKLEKAFP
ITMLMSCLFSGTQNTYTQYHPELIKQILQNLHQARTIDVIEISPTTNDISVPNIDELKKLYEEKRKSGNLTFPESRVIEY
VTIDHENFINQTNVTQEEIDNKIKADELDEQRDIFNLVFSTKNEAETALKALNEGTDFDSIVTNIAHTTLDNITLFNIVK
NTLPNDIRNQVFSLKEGEISPILHSMFGWHIIKIKNIHKISTKDLAELSEKIAQNIKKKKATDLLYTEIQAINDKINNGT
SIQEIAESYNLSIKTANVDISGKDPSDNKIKMLETNYDAIVLAAFSAQLNKPSNFTDNDGYFFSVNVTKIEPSREKTFDE
SKEQLVYEWQHDLKAQKLSKLTQEVVIKLKSGIDINNIDGVLLKPNQVVYRNSVAAVDNPGQNYPSDLINEIFHLKKGEI
SKNYQHDISSSEQKMLIAILKDIKNADQVSNVDFKNIQEKIANDNLESLKNQLIAHLIKKYSVKINQNLIDNVR
>Mature_634_residues
MRIHMKSKAFFVKPLLIILVCSLVFIAFGASFFPGSFNNEKYIAKIGHEKLSLQDYTSAYHDELRYIQHVLNRPLTEEQI
AQFNIKLSTLNKLIENKVLTKFADSLNLKVGENSILNHIKSIKFFQDENGNFDKTKFNIGLSNAGLTERLYINKLEKAFP
ITMLMSCLFSGTQNTYTQYHPELIKQILQNLHQARTIDVIEISPTTNDISVPNIDELKKLYEEKRKSGNLTFPESRVIEY
VTIDHENFINQTNVTQEEIDNKIKADELDEQRDIFNLVFSTKNEAETALKALNEGTDFDSIVTNIAHTTLDNITLFNIVK
NTLPNDIRNQVFSLKEGEISPILHSMFGWHIIKIKNIHKISTKDLAELSEKIAQNIKKKKATDLLYTEIQAINDKINNGT
SIQEIAESYNLSIKTANVDISGKDPSDNKIKMLETNYDAIVLAAFSAQLNKPSNFTDNDGYFFSVNVTKIEPSREKTFDE
SKEQLVYEWQHDLKAQKLSKLTQEVVIKLKSGIDINNIDGVLLKPNQVVYRNSVAAVDNPGQNYPSDLINEIFHLKKGEI
SKNYQHDISSSEQKMLIAILKDIKNADQVSNVDFKNIQEKIANDNLESLKNQLIAHLIKKYSVKINQNLIDNVR

Specific function: PPIases accelerate the folding of proteins. Seems to be involved in the folding of outer membrane proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786645, Length=600, Percent_Identity=23, Blast_Score=100, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 72379; Mature: 72379

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIHMKSKAFFVKPLLIILVCSLVFIAFGASFFPGSFNNEKYIAKIGHEKLSLQDYTSAY
CEEEECCCHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCCEEECCCHHCCHHHHHHHH
HDELRYIQHVLNRPLTEEQIAQFNIKLSTLNKLIENKVLTKFADSLNLKVGENSILNHIK
HHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCEEECCHHHHHHHH
SIKFFQDENGNFDKTKFNIGLSNAGLTERLYINKLEKAFPITMLMSCLFSGTQNTYTQYH
HHHEEECCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHC
PELIKQILQNLHQARTIDVIEISPTTNDISVPNIDELKKLYEEKRKSGNLTFPESRVIEY
HHHHHHHHHHHHHHCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHEEEE
VTIDHENFINQTNVTQEEIDNKIKADELDEQRDIFNLVFSTKNEAETALKALNEGTDFDS
EEECCHHHCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHH
IVTNIAHTTLDNITLFNIVKNTLPNDIRNQVFSLKEGEISPILHSMFGWHIIKIKNIHKI
HHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHCEEEEEECCCCCC
STKDLAELSEKIAQNIKKKKATDLLYTEIQAINDKINNGTSIQEIAESYNLSIKTANVDI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCEEEEEEEEE
SGKDPSDNKIKMLETNYDAIVLAAFSAQLNKPSNFTDNDGYFFSVNVTKIEPSREKTFDE
CCCCCCCCCEEEEECCCCEEEEEEHHHHCCCCCCCCCCCCEEEEEEEEEECCCHHHHHHH
SKEQLVYEWQHDLKAQKLSKLTQEVVIKLKSGIDINNIDGVLLKPNQVVYRNSVAAVDNP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCEEEEECCEEECCCC
GQNYPSDLINEIFHLKKGEISKNYQHDISSSEQKMLIAILKDIKNADQVSNVDFKNIQEK
CCCCHHHHHHHHHHCCCCCCCCCHHHCCCCCHHHHHHHHHHHHCCHHHHCCCCHHHHHHH
IANDNLESLKNQLIAHLIKKYSVKINQNLIDNVR
HCCCCHHHHHHHHHHHHHHHHHHHCCHHHHCCCC
>Mature Secondary Structure
MRIHMKSKAFFVKPLLIILVCSLVFIAFGASFFPGSFNNEKYIAKIGHEKLSLQDYTSAY
CEEEECCCHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCCEEECCCHHCCHHHHHHHH
HDELRYIQHVLNRPLTEEQIAQFNIKLSTLNKLIENKVLTKFADSLNLKVGENSILNHIK
HHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCEEECCHHHHHHHH
SIKFFQDENGNFDKTKFNIGLSNAGLTERLYINKLEKAFPITMLMSCLFSGTQNTYTQYH
HHHEEECCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHC
PELIKQILQNLHQARTIDVIEISPTTNDISVPNIDELKKLYEEKRKSGNLTFPESRVIEY
HHHHHHHHHHHHHHCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHEEEE
VTIDHENFINQTNVTQEEIDNKIKADELDEQRDIFNLVFSTKNEAETALKALNEGTDFDS
EEECCHHHCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHH
IVTNIAHTTLDNITLFNIVKNTLPNDIRNQVFSLKEGEISPILHSMFGWHIIKIKNIHKI
HHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHCEEEEEECCCCCC
STKDLAELSEKIAQNIKKKKATDLLYTEIQAINDKINNGTSIQEIAESYNLSIKTANVDI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCEEEEEEEEE
SGKDPSDNKIKMLETNYDAIVLAAFSAQLNKPSNFTDNDGYFFSVNVTKIEPSREKTFDE
CCCCCCCCCEEEEECCCCEEEEEEHHHHCCCCCCCCCCCCEEEEEEEEEECCCHHHHHHH
SKEQLVYEWQHDLKAQKLSKLTQEVVIKLKSGIDINNIDGVLLKPNQVVYRNSVAAVDNP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCEEEEECCEEECCCC
GQNYPSDLINEIFHLKKGEISKNYQHDISSSEQKMLIAILKDIKNADQVSNVDFKNIQEK
CCCCHHHHHHHHHHCCCCCCCCCHHHCCCCCHHHHHHHHHHHHCCHHHHCCCCHHHHHHH
IANDNLESLKNQLIAHLIKKYSVKINQNLIDNVR
HCCCCHHHHHHHHHHHHHHHHHHHCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]