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The map label for this gene is ubiG [H]

Identifier: 88607839

GI number: 88607839

Start: 632557

End: 633267

Strand: Reverse

Name: ubiG [H]

Synonym: APH_0606

Alternate gene names: 88607839

Gene position: 633267-632557 (Counterclockwise)

Preceding gene: 88607876

Following gene: 88607122

Centisome position: 43.04

GC content: 39.94

Gene sequence:

>711_bases
GTGAGTAATGTTGACGAATCAGAGCTGGTGAAGTTCTCAAATTTGGCTTCAGAATGGTGGGATGGGGAGTCTTTTTCAGC
TTTGCACAGGATAAATCCTTTGCGCGTTCAGTATATTCTTGAAAATTTACAAGAGGCTACTAACTCAGGTAAAAGGCTTT
TGGATATCGGTTGTGGTGGTGGGCTTATTTGCGAAGCCATGGCAAGGCTTGGTTTTAGTGTCACTGGAGTAGATCCATGT
AGAGAAGGAATAGAAGCTGCTAGACAGCACGCTGCTATCGAAGGCTTAGATATAGAGTACCATTTTACGGATATAGAGTC
TTTTATACACTCCTCAGAGTGTTCTTCTTACGATATCATCACCTTAATGGAAGTTGTAGAGCATATCCCTGATTTGACTG
AATTTTTATCTAGCTCCTGTAAGTTACTGAAACCTGGAGGTATGCTTTTCATTTCTACACTAAACAGAACTATCAAATCC
ATGTTACTTGGTAAGATAGCTGCGGAGTATATACTTCGCATGGTGCCTCCTGGCACGCACCAGTGGAAGAAGTTTGTCAA
GCCTTCAGAGATTCACGATGCCCTATTAAAAAGCAGAGTGCTCGTTAAAGATATAAAAGGCATTACCTATAAAATATTGC
ATAACGATTGGGTCTTAAATGATAGAGATATAAGTGTAAACTACATATTAGCCGCTCAAAAAGAGCAATAA

Upstream 100 bases:

>100_bases
AATACAGTACAGTTAATAAAGCGTAGTATTTCTGCTACTGAATAGGAGGAGTCACACCATAATATGAGTATTGTAGCATC
TATTTTTGGGTTGTTTTTTT

Downstream 100 bases:

>100_bases
TCTACTTAGTGATGTTTATACGTAGTGTGTACCACAGAATGTACTACTATTTAGGTTAGGTGTTATAGGCATTTCTTTTG
CCGTCGTGAATACCATATAG

Product: 3-demethylubiquinone-9 3-methyltransferase

Products: NA

Alternate protein names: 3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase; DHHB methyltransferase [H]

Number of amino acids: Translated: 236; Mature: 235

Protein sequence:

>236_residues
MSNVDESELVKFSNLASEWWDGESFSALHRINPLRVQYILENLQEATNSGKRLLDIGCGGGLICEAMARLGFSVTGVDPC
REGIEAARQHAAIEGLDIEYHFTDIESFIHSSECSSYDIITLMEVVEHIPDLTEFLSSSCKLLKPGGMLFISTLNRTIKS
MLLGKIAAEYILRMVPPGTHQWKKFVKPSEIHDALLKSRVLVKDIKGITYKILHNDWVLNDRDISVNYILAAQKEQ

Sequences:

>Translated_236_residues
MSNVDESELVKFSNLASEWWDGESFSALHRINPLRVQYILENLQEATNSGKRLLDIGCGGGLICEAMARLGFSVTGVDPC
REGIEAARQHAAIEGLDIEYHFTDIESFIHSSECSSYDIITLMEVVEHIPDLTEFLSSSCKLLKPGGMLFISTLNRTIKS
MLLGKIAAEYILRMVPPGTHQWKKFVKPSEIHDALLKSRVLVKDIKGITYKILHNDWVLNDRDISVNYILAAQKEQ
>Mature_235_residues
SNVDESELVKFSNLASEWWDGESFSALHRINPLRVQYILENLQEATNSGKRLLDIGCGGGLICEAMARLGFSVTGVDPCR
EGIEAARQHAAIEGLDIEYHFTDIESFIHSSECSSYDIITLMEVVEHIPDLTEFLSSSCKLLKPGGMLFISTLNRTIKSM
LLGKIAAEYILRMVPPGTHQWKKFVKPSEIHDALLKSRVLVKDIKGITYKILHNDWVLNDRDISVNYILAAQKEQ

Specific function: Ubiquinone biosynthesis. [C]

COG id: COG2227

COG function: function code H; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. UbiG/COQ3 family [H]

Homologues:

Organism=Homo sapiens, GI118600965, Length=247, Percent_Identity=36.8421052631579, Blast_Score=166, Evalue=1e-41,
Organism=Escherichia coli, GI1788564, Length=234, Percent_Identity=42.7350427350427, Blast_Score=192, Evalue=1e-50,
Organism=Caenorhabditis elegans, GI115533050, Length=224, Percent_Identity=37.0535714285714, Blast_Score=157, Evalue=4e-39,
Organism=Saccharomyces cerevisiae, GI6324476, Length=284, Percent_Identity=29.9295774647887, Blast_Score=108, Evalue=7e-25,
Organism=Drosophila melanogaster, GI281365311, Length=248, Percent_Identity=33.4677419354839, Blast_Score=143, Evalue=1e-34,
Organism=Drosophila melanogaster, GI24585589, Length=239, Percent_Identity=33.0543933054393, Blast_Score=141, Evalue=3e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013216
- InterPro:   IPR010233 [H]

Pfam domain/function: PF08241 Methyltransf_11 [H]

EC number: =2.1.1.64 [H]

Molecular weight: Translated: 26524; Mature: 26393

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNVDESELVKFSNLASEWWDGESFSALHRINPLRVQYILENLQEATNSGKRLLDIGCGG
CCCCCHHHHHHHHHHHHHHCCCCCHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEEECCCC
GLICEAMARLGFSVTGVDPCREGIEAARQHAAIEGLDIEYHFTDIESFIHSSECSSYDII
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHCCCCCCHHH
TLMEVVEHIPDLTEFLSSSCKLLKPGGMLFISTLNRTIKSMLLGKIAAEYILRMVPPGTH
HHHHHHHHCCHHHHHHHCCCCEECCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
QWKKFVKPSEIHDALLKSRVLVKDIKGITYKILHNDWVLNDRDISVNYILAAQKEQ
HHHHCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCEEECCCCCEEEEEEEECCCC
>Mature Secondary Structure 
SNVDESELVKFSNLASEWWDGESFSALHRINPLRVQYILENLQEATNSGKRLLDIGCGG
CCCCHHHHHHHHHHHHHHCCCCCHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEEECCCC
GLICEAMARLGFSVTGVDPCREGIEAARQHAAIEGLDIEYHFTDIESFIHSSECSSYDII
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHCCCCCCHHH
TLMEVVEHIPDLTEFLSSSCKLLKPGGMLFISTLNRTIKSMLLGKIAAEYILRMVPPGTH
HHHHHHHHCCHHHHHHHCCCCEECCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
QWKKFVKPSEIHDALLKSRVLVKDIKGITYKILHNDWVLNDRDISVNYILAAQKEQ
HHHHCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCEEECCCCCEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA