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The map label for this gene is lysK [H]

Identifier: 88607876

GI number: 88607876

Start: 633323

End: 634867

Strand: Reverse

Name: lysK [H]

Synonym: APH_0607

Alternate gene names: 88607876

Gene position: 634867-633323 (Counterclockwise)

Preceding gene: 88607320

Following gene: 88607839

Centisome position: 43.15

GC content: 39.81

Gene sequence:

>1545_bases
ATGAAGGGAGAAGTGGTATCTTGGCCGTTTATAGAAGCTGAAAAAATTTTAAAGGCATTTGGTGATAGCGAGGAAATAAT
ACTTGCTACAGGGTATGGTCCGTCCGGATTGCCTCATATAGGAACTTTTGGTGAAGTACAAAGAACAGTATATGTAGCTA
ATGCACTGCGAGAGATCTCTCCTAAAACTAAAACAAGGATTTTAGCATTCTCTGATGATATGGATGGGTTGCGGAAAGTT
CCTGATAACGTACCAAACCGTGAAATGCTAGAGAAACATCTGGGACAGTTACTGACCTCAATACCTGATCCGTTCGGCAC
ATCCTCAAGCTATGGCCATCATATGAACGGCACTTTCTGTGCTTTTTTAGACAGATTTGGGTTTGAATACGAATTTATTA
GTGCAACAGAGTGCTACAGATCCGGTAGATATGATGATGTACTGCTACGGCTACTAAGAAATTATGATAAGGCCGTAAGC
ATACTGTTGCCAACACTTGGCGAAGAGCGTCAAAAAACTTATAGTCCGTTTCTGCCCATATGTGAAAAAACATCTAGAGT
GCTGCAGGTGACTATAGTCAAAACAGACGTAGAAAAAGGAACTATTTTTTATCAAAATGAAGACGGAGACTTGGTAGAGG
TAAAAGTAACCGGTGGACATTGTAAATTACAGTGGAAAGCTGATTGGGGAATGCGTTGGGCCGCTTTTGGTGTGCATTAT
GAATCTCATGGTAAAGACCTAACTCCTTCTGCTAAACCGTCTGCAGAAATCTGTAAACTCCTAGGTAGAAGGCCTCCTGT
TCTGTTTCCATATGAACTTTTTCTTGATAAAGAAGGGAAGAAAATTTCCAAATCTAAGGGCAATGGTTTCTCTGTAGAAG
AGTGGCTTGCATGCGCACCGTATGAGAGCCTAGCCCTCTATATGTTTCAAAACCCGAAAAGGGCTAAGCGCTTGTGTTCT
GAAGTAGTGCCAAAATTTGTAGATGACTATCTGTCATTATTACATAAATACAATGAGGCTCCTAGTACTCACAATCCTGT
ATGGCATATACACAACGGTAATGTTCCTAAAGTAGAGCTGTATGGTTTAACTTTTTGTCTACTCATCAACATAGCATCAG
CGTGCAATGCAAACGATGTTGCGATGTTGGAGCAACTCATAAAAATATATAGGGACGGGATTGATTTAGAGAACAATACT
CTACTAAGTAGGTTATTAGAGTTCTCTGTTGCGTATTGCAGGGCATTTGTTATGCCGTCTAGATCATATAAAACACCTAC
TGCTGAGGAGAGCAACATGTTACTTGATCTAGCAAATACTCTTTCTTGCATGGATGACAGTAAATCACCTGATGAAATAC
AAAATGAAGTATTTGAGGTTGGAAAGAAGTATCTACAGCCTAGTGATCTACGTATGTGGTTTAAGATGCTGTACGAAGTG
TTACTTGGACAGAGTGATGGGCCTAGATTTGGGTCTTTTGTAAAATTGTATGGTATTGAGAATACAGTACAGTTAATAAA
GCGTAGTATTTCTGCTACTGAATAG

Upstream 100 bases:

>100_bases
AAATTACAGGCATTTTCTTAGTGCTGGGTAACATTGTAATTAAGTAAGTTATACTTATAAAAATAATGAATATTTGCATG
CTGGTGGTGGAGCAAAACAT

Downstream 100 bases:

>100_bases
GAGGAGTCACACCATAATATGAGTATTGTAGCATCTATTTTTGGGTTGTTTTTTTGTGAGTAATGTTGACGAATCAGAGC
TGGTGAAGTTCTCAAATTTG

Product: lysyl-tRNA synthetase

Products: NA

Alternate protein names: Lysine--tRNA ligase; LysRS [H]

Number of amino acids: Translated: 514; Mature: 514

Protein sequence:

>514_residues
MKGEVVSWPFIEAEKILKAFGDSEEIILATGYGPSGLPHIGTFGEVQRTVYVANALREISPKTKTRILAFSDDMDGLRKV
PDNVPNREMLEKHLGQLLTSIPDPFGTSSSYGHHMNGTFCAFLDRFGFEYEFISATECYRSGRYDDVLLRLLRNYDKAVS
ILLPTLGEERQKTYSPFLPICEKTSRVLQVTIVKTDVEKGTIFYQNEDGDLVEVKVTGGHCKLQWKADWGMRWAAFGVHY
ESHGKDLTPSAKPSAEICKLLGRRPPVLFPYELFLDKEGKKISKSKGNGFSVEEWLACAPYESLALYMFQNPKRAKRLCS
EVVPKFVDDYLSLLHKYNEAPSTHNPVWHIHNGNVPKVELYGLTFCLLINIASACNANDVAMLEQLIKIYRDGIDLENNT
LLSRLLEFSVAYCRAFVMPSRSYKTPTAEESNMLLDLANTLSCMDDSKSPDEIQNEVFEVGKKYLQPSDLRMWFKMLYEV
LLGQSDGPRFGSFVKLYGIENTVQLIKRSISATE

Sequences:

>Translated_514_residues
MKGEVVSWPFIEAEKILKAFGDSEEIILATGYGPSGLPHIGTFGEVQRTVYVANALREISPKTKTRILAFSDDMDGLRKV
PDNVPNREMLEKHLGQLLTSIPDPFGTSSSYGHHMNGTFCAFLDRFGFEYEFISATECYRSGRYDDVLLRLLRNYDKAVS
ILLPTLGEERQKTYSPFLPICEKTSRVLQVTIVKTDVEKGTIFYQNEDGDLVEVKVTGGHCKLQWKADWGMRWAAFGVHY
ESHGKDLTPSAKPSAEICKLLGRRPPVLFPYELFLDKEGKKISKSKGNGFSVEEWLACAPYESLALYMFQNPKRAKRLCS
EVVPKFVDDYLSLLHKYNEAPSTHNPVWHIHNGNVPKVELYGLTFCLLINIASACNANDVAMLEQLIKIYRDGIDLENNT
LLSRLLEFSVAYCRAFVMPSRSYKTPTAEESNMLLDLANTLSCMDDSKSPDEIQNEVFEVGKKYLQPSDLRMWFKMLYEV
LLGQSDGPRFGSFVKLYGIENTVQLIKRSISATE
>Mature_514_residues
MKGEVVSWPFIEAEKILKAFGDSEEIILATGYGPSGLPHIGTFGEVQRTVYVANALREISPKTKTRILAFSDDMDGLRKV
PDNVPNREMLEKHLGQLLTSIPDPFGTSSSYGHHMNGTFCAFLDRFGFEYEFISATECYRSGRYDDVLLRLLRNYDKAVS
ILLPTLGEERQKTYSPFLPICEKTSRVLQVTIVKTDVEKGTIFYQNEDGDLVEVKVTGGHCKLQWKADWGMRWAAFGVHY
ESHGKDLTPSAKPSAEICKLLGRRPPVLFPYELFLDKEGKKISKSKGNGFSVEEWLACAPYESLALYMFQNPKRAKRLCS
EVVPKFVDDYLSLLHKYNEAPSTHNPVWHIHNGNVPKVELYGLTFCLLINIASACNANDVAMLEQLIKIYRDGIDLENNT
LLSRLLEFSVAYCRAFVMPSRSYKTPTAEESNMLLDLANTLSCMDDSKSPDEIQNEVFEVGKKYLQPSDLRMWFKMLYEV
LLGQSDGPRFGSFVKLYGIENTVQLIKRSISATE

Specific function: Unknown

COG id: COG1384

COG function: function code J; Lysyl-tRNA synthetase (class I)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008925
- InterPro:   IPR020751
- InterPro:   IPR001412
- InterPro:   IPR002904
- InterPro:   IPR020754
- InterPro:   IPR020756
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01921 tRNA-synt_1f [H]

EC number: =6.1.1.6 [H]

Molecular weight: Translated: 58187; Mature: 58187

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGEVVSWPFIEAEKILKAFGDSEEIILATGYGPSGLPHIGTFGEVQRTVYVANALREIS
CCCCEECCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCC
PKTKTRILAFSDDMDGLRKVPDNVPNREMLEKHLGQLLTSIPDPFGTSSSYGHHMNGTFC
CCHHEEEEEECCCHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHH
AFLDRFGFEYEFISATECYRSGRYDDVLLRLLRNYDKAVSILLPTLGEERQKTYSPFLPI
HHHHHHCCCEEEECHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHH
CEKTSRVLQVTIVKTDVEKGTIFYQNEDGDLVEVKVTGGHCKLQWKADWGMRWAAFGVHY
HHCCCCEEEEEEEEEECCCCEEEEECCCCCEEEEEEECCEEEEEEECCCCCEEEEEEEEE
ESHGKDLTPSAKPSAEICKLLGRRPPVLFPYELFLDKEGKKISKSKGNGFSVEEWLACAP
CCCCCCCCCCCCCHHHHHHHHCCCCCEEECHHHEECCCCCCHHCCCCCCCCHHHHHHHCC
YESLALYMFQNPKRAKRLCSEVVPKFVDDYLSLLHKYNEAPSTHNPVWHIHNGNVPKVEL
HHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCEEEE
YGLTFCLLINIASACNANDVAMLEQLIKIYRDGIDLENNTLLSRLLEFSVAYCRAFVMPS
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
RSYKTPTAEESNMLLDLANTLSCMDDSKSPDEIQNEVFEVGKKYLQPSDLRMWFKMLYEV
CCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LLGQSDGPRFGSFVKLYGIENTVQLIKRSISATE
HHCCCCCCCCCCEEEEECCHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKGEVVSWPFIEAEKILKAFGDSEEIILATGYGPSGLPHIGTFGEVQRTVYVANALREIS
CCCCEECCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCC
PKTKTRILAFSDDMDGLRKVPDNVPNREMLEKHLGQLLTSIPDPFGTSSSYGHHMNGTFC
CCHHEEEEEECCCHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHH
AFLDRFGFEYEFISATECYRSGRYDDVLLRLLRNYDKAVSILLPTLGEERQKTYSPFLPI
HHHHHHCCCEEEECHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHH
CEKTSRVLQVTIVKTDVEKGTIFYQNEDGDLVEVKVTGGHCKLQWKADWGMRWAAFGVHY
HHCCCCEEEEEEEEEECCCCEEEEECCCCCEEEEEEECCEEEEEEECCCCCEEEEEEEEE
ESHGKDLTPSAKPSAEICKLLGRRPPVLFPYELFLDKEGKKISKSKGNGFSVEEWLACAP
CCCCCCCCCCCCCHHHHHHHHCCCCCEEECHHHEECCCCCCHHCCCCCCCCHHHHHHHCC
YESLALYMFQNPKRAKRLCSEVVPKFVDDYLSLLHKYNEAPSTHNPVWHIHNGNVPKVEL
HHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCEEEE
YGLTFCLLINIASACNANDVAMLEQLIKIYRDGIDLENNTLLSRLLEFSVAYCRAFVMPS
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
RSYKTPTAEESNMLLDLANTLSCMDDSKSPDEIQNEVFEVGKKYLQPSDLRMWFKMLYEV
CCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LLGQSDGPRFGSFVKLYGIENTVQLIKRSISATE
HHCCCCCCCCCCEEEEECCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9823893 [H]