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The map label for this gene is sdhB [H]

Identifier: 88607770

GI number: 88607770

Start: 164409

End: 165197

Strand: Direct

Name: sdhB [H]

Synonym: APH_0162

Alternate gene names: 88607770

Gene position: 164409-165197 (Clockwise)

Preceding gene: 88607039

Following gene: 88606875

Centisome position: 11.17

GC content: 41.7

Gene sequence:

>789_bases
ATGGTGCAGTTTTCTTTGCCAAAAAACTCCAAGATAAACCCGAATGGTAAGGTATACAATGCTACGGAGGGTGCTAAGCG
CACTGGATGTTTTAAGATATATAGGTGGTCACCTGATGACGGAGAGAATCCGAGGATTGATACCTACTATATAGATTTGG
ACAAATGTGGGCAGATGGTCCTTGATGCGCTAATTAAAGTTAAGAATGAGTATGACTCGACTTTGACTTTTAGGAGGTCA
TGTCGTGAGGGGATATGTGGATCGTGTGCGATGAATATAGATGGCACGAACACTTTGGCATGTACGAAGTATATTTCTGA
TATTAAGGGAGATGTGAAAATATTTCCCTTACCGCATATGGATGTTATCAAAGATTTGGTGCCGGATTTAAGTAATTTTT
ACAAGCAATATAAGTCTATAAGTCCTTGGTTGAAGTCTGATGGTGCGAGGTCTGATAGGGAGGAGCATCTTCAGAGCATA
GAGGACAGGAGTAAGTTGGACAAGGTATACGATTGCATTTTGTGTGCGTGTTGTAGTACAAGTTGTCCGAGTTATTGGTG
GAATCCAGATAAGTATTTGGGACCTGCGGCGTTGTTGCAGGTATACAGGTGGTTGGTTGATAGTAGGGATACGGCGACAG
AGGAGCGTCTTGCGTTTTTAGAGGATGCTTTTAAGTTATACAGGTGTCATACTATCATGAATTGTACTAAGACTTGTCCC
AAGGATCTGAATCCTGCTAAGGCGATAGCGAAAATAAAGCAGATGATGATAAAAGGATTGGAGCTCTAG

Upstream 100 bases:

>100_bases
AAGTGAAGATAGGCTATAAAGAGGTAGCTACTTATACTTTGACAAATGAAGTAGAGTATTTTCCTCCGCAGAAAAGGGTT
TATTAGAGAGGGTTAATAAT

Downstream 100 bases:

>100_bases
ATGGTGGATGAGGCTACGGAATATACGAAGCGTTTGGTAGTGCCGGCACTTGAGAATGTGTTATATCAGGAACATAAGGT
GTTGGATCATGGTTTTGTGC

Product: succinate dehydrogenase iron-sulfur subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 262; Mature: 262

Protein sequence:

>262_residues
MVQFSLPKNSKINPNGKVYNATEGAKRTGCFKIYRWSPDDGENPRIDTYYIDLDKCGQMVLDALIKVKNEYDSTLTFRRS
CREGICGSCAMNIDGTNTLACTKYISDIKGDVKIFPLPHMDVIKDLVPDLSNFYKQYKSISPWLKSDGARSDREEHLQSI
EDRSKLDKVYDCILCACCSTSCPSYWWNPDKYLGPAALLQVYRWLVDSRDTATEERLAFLEDAFKLYRCHTIMNCTKTCP
KDLNPAKAIAKIKQMMIKGLEL

Sequences:

>Translated_262_residues
MVQFSLPKNSKINPNGKVYNATEGAKRTGCFKIYRWSPDDGENPRIDTYYIDLDKCGQMVLDALIKVKNEYDSTLTFRRS
CREGICGSCAMNIDGTNTLACTKYISDIKGDVKIFPLPHMDVIKDLVPDLSNFYKQYKSISPWLKSDGARSDREEHLQSI
EDRSKLDKVYDCILCACCSTSCPSYWWNPDKYLGPAALLQVYRWLVDSRDTATEERLAFLEDAFKLYRCHTIMNCTKTCP
KDLNPAKAIAKIKQMMIKGLEL
>Mature_262_residues
MVQFSLPKNSKINPNGKVYNATEGAKRTGCFKIYRWSPDDGENPRIDTYYIDLDKCGQMVLDALIKVKNEYDSTLTFRRS
CREGICGSCAMNIDGTNTLACTKYISDIKGDVKIFPLPHMDVIKDLVPDLSNFYKQYKSISPWLKSDGARSDREEHLQSI
EDRSKLDKVYDCILCACCSTSCPSYWWNPDKYLGPAALLQVYRWLVDSRDTATEERLAFLEDAFKLYRCHTIMNCTKTCP
KDLNPAKAIAKIKQMMIKGLEL

Specific function: Two Distinct, Membrane-Bound, FAD-Containing Enzymes Are Responsible For The Catalysis Of Fumarate And Succinate Interconversion; The Fumarate Reductase Is Used In Anaerobic Growth, And The Succinate Dehydrogenase Is Used In Aerobic Growth. [C]

COG id: COG0479

COG function: function code C; Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI115387094, Length=240, Percent_Identity=69.5833333333333, Blast_Score=349, Evalue=1e-96,
Organism=Escherichia coli, GI1786943, Length=232, Percent_Identity=53.8793103448276, Blast_Score=263, Evalue=1e-71,
Organism=Escherichia coli, GI1790596, Length=223, Percent_Identity=30.4932735426009, Blast_Score=136, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17533915, Length=233, Percent_Identity=60.9442060085837, Blast_Score=306, Evalue=6e-84,
Organism=Saccharomyces cerevisiae, GI6322987, Length=232, Percent_Identity=64.2241379310345, Blast_Score=319, Evalue=3e-88,
Organism=Drosophila melanogaster, GI17137106, Length=231, Percent_Identity=64.5021645021645, Blast_Score=332, Evalue=1e-91,
Organism=Drosophila melanogaster, GI24643156, Length=234, Percent_Identity=62.3931623931624, Blast_Score=322, Evalue=1e-88,

Paralogues:

None

Copy number: 480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006058
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR004489 [H]

Pfam domain/function: NA

EC number: =1.3.99.1 [H]

Molecular weight: Translated: 29942; Mature: 29942

Theoretical pI: Translated: 8.06; Mature: 8.06

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2 ; PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
8.0 %Cys+Met (Translated Protein)
5.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
8.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVQFSLPKNSKINPNGKVYNATEGAKRTGCFKIYRWSPDDGENPRIDTYYIDLDKCGQMV
CEEECCCCCCCCCCCCCEEECCCCCCCCCCEEEEEECCCCCCCCCEEEEEECHHHHHHHH
LDALIKVKNEYDSTLTFRRSCREGICGSCAMNIDGTNTLACTKYISDIKGDVKIFPLPHM
HHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHCCCCEEEECCCCH
DVIKDLVPDLSNFYKQYKSISPWLKSDGARSDREEHLQSIEDRSKLDKVYDCILCACCST
HHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SCPSYWWNPDKYLGPAALLQVYRWLVDSRDTATEERLAFLEDAFKLYRCHTIMNCTKTCP
CCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
KDLNPAKAIAKIKQMMIKGLEL
CCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVQFSLPKNSKINPNGKVYNATEGAKRTGCFKIYRWSPDDGENPRIDTYYIDLDKCGQMV
CEEECCCCCCCCCCCCCEEECCCCCCCCCCEEEEEECCCCCCCCCEEEEEECHHHHHHHH
LDALIKVKNEYDSTLTFRRSCREGICGSCAMNIDGTNTLACTKYISDIKGDVKIFPLPHM
HHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHCCCCEEEECCCCH
DVIKDLVPDLSNFYKQYKSISPWLKSDGARSDREEHLQSIEDRSKLDKVYDCILCACCST
HHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SCPSYWWNPDKYLGPAALLQVYRWLVDSRDTATEERLAFLEDAFKLYRCHTIMNCTKTCP
CCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
KDLNPAKAIAKIKQMMIKGLEL
CCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA