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The map label for this gene is thyX [H]

Identifier: 88606875

GI number: 88606875

Start: 165198

End: 166064

Strand: Direct

Name: thyX [H]

Synonym: APH_0163

Alternate gene names: 88606875

Gene position: 165198-166064 (Clockwise)

Preceding gene: 88607770

Following gene: 88607041

Centisome position: 11.23

GC content: 43.83

Gene sequence:

>867_bases
ATGGTGGATGAGGCTACGGAATATACGAAGCGTTTGGTAGTGCCGGCACTTGAGAATGTGTTATATCAGGAACATAAGGT
GTTGGATCATGGTTTTGTGCGGGTTATTGACTACATGGGGTCTGATGCCTCGATTGTTCAAGCAGCGCGGGTTTCATACG
GTAAGGGAACTAAACAAGTAAGTCAAGATGCCGCGCTTATAGGGTATCTTATGAGGCATGCTCATACGTCTCCTTTTGAA
ATGTGTGAGATAAAGTTTCACATAAAATTGCCTATTTTCGTGGCGCGTCAATGGGTTAGGCATAGGACTGCTAGTATAAA
TGAGAGTTCTGCTAGGTATTCTGTAGTTGAGAACGAGTTTTACATTCCGGAAGCTTGCGATGTTGCAGAGCAGTCTTCTA
ACAATGCTCAGGGTAGGGGTAATCCTCTAACGTCAGAGGTGGCTCAGAATGTAATAGGCATGTTTAAGGACAACTCTGAC
AGTATGTATGCATCTTATGAATCAATGTTGAGTGATGGTGTTGCGAGAGAGTTAGCTAGAATGACTCTTCCTTTGAACTG
CTACACGCACTGGTATTGGAAAGTGGATTTGCATAATTTGCTCAGGTTTGTGACTCTACGCTTAGGAAGTGGGGCTCAGT
ACGAGTTGCGCGCTTACGCTGGAAAAATATTGGATATAATTGCACTGTGGGTTCCTATGGTGTATGCAGCATATATGGAG
TATTGCTTTGAATCAAAGACCTTATCCAAAAGCGCGTTATCTGTCATTAGGATGCTGTTGAAAGGTGAGAAAGTCTCTAG
GGAAGACGTGGGCATGAGTAAGAGGGAATGGGGTGAACTGATGGCTACTTTGTATCCTGATGAGTAG

Upstream 100 bases:

>100_bases
TACTATCATGAATTGTACTAAGACTTGTCCCAAGGATCTGAATCCTGCTAAGGCGATAGCGAAAATAAAGCAGATGATGA
TAAAAGGATTGGAGCTCTAG

Downstream 100 bases:

>100_bases
TAAAATATTCTTATCGAATTTGCATCTGTCGCTAGTATAGGCGGCTCAGCTGGTTGCATTTTTGGGATTTGACCATTGAG
AGCTGACACTTTGAACCATG

Product: FAD-dependent thymidylate synthase

Products: NA

Alternate protein names: TS; TSase [H]

Number of amino acids: Translated: 288; Mature: 288

Protein sequence:

>288_residues
MVDEATEYTKRLVVPALENVLYQEHKVLDHGFVRVIDYMGSDASIVQAARVSYGKGTKQVSQDAALIGYLMRHAHTSPFE
MCEIKFHIKLPIFVARQWVRHRTASINESSARYSVVENEFYIPEACDVAEQSSNNAQGRGNPLTSEVAQNVIGMFKDNSD
SMYASYESMLSDGVARELARMTLPLNCYTHWYWKVDLHNLLRFVTLRLGSGAQYELRAYAGKILDIIALWVPMVYAAYME
YCFESKTLSKSALSVIRMLLKGEKVSREDVGMSKREWGELMATLYPDE

Sequences:

>Translated_288_residues
MVDEATEYTKRLVVPALENVLYQEHKVLDHGFVRVIDYMGSDASIVQAARVSYGKGTKQVSQDAALIGYLMRHAHTSPFE
MCEIKFHIKLPIFVARQWVRHRTASINESSARYSVVENEFYIPEACDVAEQSSNNAQGRGNPLTSEVAQNVIGMFKDNSD
SMYASYESMLSDGVARELARMTLPLNCYTHWYWKVDLHNLLRFVTLRLGSGAQYELRAYAGKILDIIALWVPMVYAAYME
YCFESKTLSKSALSVIRMLLKGEKVSREDVGMSKREWGELMATLYPDE
>Mature_288_residues
MVDEATEYTKRLVVPALENVLYQEHKVLDHGFVRVIDYMGSDASIVQAARVSYGKGTKQVSQDAALIGYLMRHAHTSPFE
MCEIKFHIKLPIFVARQWVRHRTASINESSARYSVVENEFYIPEACDVAEQSSNNAQGRGNPLTSEVAQNVIGMFKDNSD
SMYASYESMLSDGVARELARMTLPLNCYTHWYWKVDLHNLLRFVTLRLGSGAQYELRAYAGKILDIIALWVPMVYAAYME
YCFESKTLSKSALSVIRMLLKGEKVSREDVGMSKREWGELMATLYPDE

Specific function: Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate [H]

COG id: COG1351

COG function: function code F; Predicted alternative thymidylate synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thyX (flavin-dependent thymidylate synthase) domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003669 [H]

Pfam domain/function: PF02511 Thy1 [H]

EC number: =2.1.1.148 [H]

Molecular weight: Translated: 32771; Mature: 32771

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVDEATEYTKRLVVPALENVLYQEHKVLDHGFVRVIDYMGSDASIVQAARVSYGKGTKQV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHH
SQDAALIGYLMRHAHTSPFEMCEIKFHIKLPIFVARQWVRHRTASINESSARYSVVENEF
HHHHHHHHHHHHHCCCCCCCEEEEEEEEECHHHHHHHHHHHHHCCCCCCCCCEEEECCCC
YIPEACDVAEQSSNNAQGRGNPLTSEVAQNVIGMFKDNSDSMYASYESMLSDGVARELAR
CCCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
MTLPLNCYTHWYWKVDLHNLLRFVTLRLGSGAQYELRAYAGKILDIIALWVPMVYAAYME
HHCCEEEEEEEEEEECHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
YCFESKTLSKSALSVIRMLLKGEKVSREDVGMSKREWGELMATLYPDE
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCHHHHHHHHHHCCCCC
>Mature Secondary Structure
MVDEATEYTKRLVVPALENVLYQEHKVLDHGFVRVIDYMGSDASIVQAARVSYGKGTKQV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHH
SQDAALIGYLMRHAHTSPFEMCEIKFHIKLPIFVARQWVRHRTASINESSARYSVVENEF
HHHHHHHHHHHHHCCCCCCCEEEEEEEEECHHHHHHHHHHHHHCCCCCCCCCEEEECCCC
YIPEACDVAEQSSNNAQGRGNPLTSEVAQNVIGMFKDNSDSMYASYESMLSDGVARELAR
CCCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
MTLPLNCYTHWYWKVDLHNLLRFVTLRLGSGAQYELRAYAGKILDIIALWVPMVYAAYME
HHCCEEEEEEEEEEECHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
YCFESKTLSKSALSVIRMLLKGEKVSREDVGMSKREWGELMATLYPDE
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA