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The map label for this gene is cutA [H]

Identifier: 88607755

GI number: 88607755

Start: 608223

End: 608558

Strand: Reverse

Name: cutA [H]

Synonym: APH_0581

Alternate gene names: 88607755

Gene position: 608558-608223 (Counterclockwise)

Preceding gene: 88607151

Following gene: 88607352

Centisome position: 41.36

GC content: 35.42

Gene sequence:

>336_bases
ATGAGTAGTACGCTGCTTTTAATATACACTACAATGCCAGATCATGATAGCGCTCGTAATATGAGTGAACTTTTACTACG
GGAAAAACTCATATCCTGTTCTAATATGATTAATGGTATAACATCCATGTATATATGGAATGGGGATATTAATACTAGCA
CCGAATGCATAGTAATAATGAAGACTACTGCCGGTTTATATGAAGAGATTGCGAAAAAAATAAAGGAACTTCACCCTTAT
AACACACCAGCAATATTCTCAATCCCTACTCATAACTGCGACCCAGAATTCTTAAAGTGGGTAAATTCCTCTACCTATAG
AGATATTGACTGCTAA

Upstream 100 bases:

>100_bases
AGCAATTATTACAAAAAGTAGATGAGGCTCTAGCGTGCAAAGGCCAGAAATAAGCACAATATGCACAGAAATATAATATC
CCTAGAGAGGACTTGTCGAT

Downstream 100 bases:

>100_bases
AGCCATTCTTAGACACTGAAGAAAGATGGAGTTTTAGTTATAGTGAGTGTGTTGCTCGCGTTTTTGGGAATCTCCGTCAC
AGTTGTTGCCTCGATTGCTA

Product: periplasmic divalent cation tolerance protein CutA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 111; Mature: 110

Protein sequence:

>111_residues
MSSTLLLIYTTMPDHDSARNMSELLLREKLISCSNMINGITSMYIWNGDINTSTECIVIMKTTAGLYEEIAKKIKELHPY
NTPAIFSIPTHNCDPEFLKWVNSSTYRDIDC

Sequences:

>Translated_111_residues
MSSTLLLIYTTMPDHDSARNMSELLLREKLISCSNMINGITSMYIWNGDINTSTECIVIMKTTAGLYEEIAKKIKELHPY
NTPAIFSIPTHNCDPEFLKWVNSSTYRDIDC
>Mature_110_residues
SSTLLLIYTTMPDHDSARNMSELLLREKLISCSNMINGITSMYIWNGDINTSTECIVIMKTTAGLYEEIAKKIKELHPYN
TPAIFSIPTHNCDPEFLKWVNSSTYRDIDC

Specific function: Involved in resistance toward heavy metals [H]

COG id: COG1324

COG function: function code P; Uncharacterized protein involved in tolerance to divalent cations

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CutA family [H]

Homologues:

Organism=Homo sapiens, GI62526026, Length=97, Percent_Identity=26.8041237113402, Blast_Score=67, Evalue=3e-12,
Organism=Homo sapiens, GI62198241, Length=97, Percent_Identity=26.8041237113402, Blast_Score=67, Evalue=3e-12,
Organism=Homo sapiens, GI62526024, Length=97, Percent_Identity=26.8041237113402, Blast_Score=67, Evalue=3e-12,
Organism=Homo sapiens, GI62526022, Length=97, Percent_Identity=26.8041237113402, Blast_Score=67, Evalue=3e-12,
Organism=Homo sapiens, GI7706244, Length=97, Percent_Identity=26.8041237113402, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1790579, Length=99, Percent_Identity=33.3333333333333, Blast_Score=80, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI32565476, Length=101, Percent_Identity=32.6732673267327, Blast_Score=77, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24641937, Length=101, Percent_Identity=29.7029702970297, Blast_Score=77, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004323
- InterPro:   IPR011322 [H]

Pfam domain/function: PF03091 CutA1 [H]

EC number: NA

Molecular weight: Translated: 12669; Mature: 12538

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
9.0 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
8.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSTLLLIYTTMPDHDSARNMSELLLREKLISCSNMINGITSMYIWNGDINTSTECIVIM
CCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCEEEEE
KTTAGLYEEIAKKIKELHPYNTPAIFSIPTHNCDPEFLKWVNSSTYRDIDC
ECCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
SSTLLLIYTTMPDHDSARNMSELLLREKLISCSNMINGITSMYIWNGDINTSTECIVIM
CCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCEEEEE
KTTAGLYEEIAKKIKELHPYNTPAIFSIPTHNCDPEFLKWVNSSTYRDIDC
ECCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9679194 [H]