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The map label for this gene is zraS [C]

Identifier: 88607151

GI number: 88607151

Start: 608606

End: 611050

Strand: Reverse

Name: zraS [C]

Synonym: APH_0582

Alternate gene names: 88607151

Gene position: 611050-608606 (Counterclockwise)

Preceding gene: 88607412

Following gene: 88607755

Centisome position: 41.53

GC content: 37.22

Gene sequence:

>2445_bases
ATGATTCGTGACTATGGAATTACAAAGATAAAAGCCGCAATTGTGGTGATATTACCATTACTTTGTATTTTCAGCATATA
CCTGTTCGGCATCGAAAACGGGTACGTTAGTATGGTGTTTAACTGTTTATTCACAAGCGCCATCGTCCTAGTGCTCTTAC
AAAAGCTAAGTCGCTATCCTAAGGTTATAGCTGCTATTGAGTATCAGAATATGATTTTTGCAAATGCATTAAATCACGAT
ACAGAGTTTTGCTTGATATTAAACGGACAGGGAAATGTTGTATACTCAGATGCCAGGTTCAATACGCGATTCCAAAATTT
TACTCAAAATGGCAATCTGAACCTATATAACGTGCTTAAATTAGGTAATTTGAGCGATAAGGAAATATCGAGATTTTTAG
GTGCCTTAAAGAACAAATCACCTGTACGAACATATTGTTCAGTCAGTAAGAAAAATACCGTTTCAAACTTCTCTCTTATC
CTTGATCCGATAGTAAATAATCCTCAAGTTGACATAAATACCGAAGCAACATTTAGTCTATTTCTTAGCCCCCTTTCAAG
GCCCCAGGACTACTTCGTACTTAAAGCAGTAAAAATTACGAAGGAAGACGTGCATGAAAAGCTATTAAATAGACACAACG
TAGGATCTTACTTACTCAGTCAGGATGGGGTCATAATTTCTGCAAATGCAACGTTTTTAAAAATTTTTGAGTTAGACACT
TTAAAGCGTCATACATTATTGAGCGACTTTCTTAGCAAAAACCAATCAGATAGCGAAACCGATGAAGTTGTATTTTTGAC
ATCAACTGGCACAATGTTCAGAGCATATGTCACACAAGAAGTCTTTCACGATAAAAATAACAATAGCTACATATATGGAT
TAATCACGCCTAAAAAATTCGATCTCACCGATTATCAGTTAAACCCGTGCTTTATCCATTCTCCCATCGCTATTGCACAG
TGCAACATGGATGGAAAAATTATAAAGTACAACAAAGCGTTTGAGGCACTTGTAGATAAGCAACATCAAGAATACATATA
CTCTCACCTTACGGCCGTATACAGTAAGAAGATAAAAAAGTACTTACAAAACAGCGTTATAAACAATATGTCCATAGAGG
GACAGCTCTGCAACAAGACTTACGTTAAGATATACATGAACAAGCTGATACATAATAACACTGTATCAGTGGTGTGCTAC
ATAACTGACAGCGCTGACCGTAAAAGTTTAGAAACTCAATTGGAACAATCGCAAAAAGTACAAGCAATTGGTCAATTAAC
CGGTGGGATAGCACACGATTTTAATAATATACTGACCGCAATTATAGGATTTTGCGACCTGTTACTTATTCAACACCCTG
CTACCGACCCTTCGTTTAGGGATATTATGCAAATAAAGCAGAATGCTAATCGTGCTGCCAATTTAATTAGGCAACTGATG
GCATTTTCACGCAAACAGACTCTACAACCCAAGATTCTAGACATAAACAACATTGTTGCAGATCTAGCACAAATGATAAA
GAGGCTCATCAGTGAGGATATCGAACTCAATATTTACTATCAGGAAAACATAGGGCTTGTAATGGTTGATCTTAGTCAGC
TAGAGCAGGTAATTGTCAATCTAGTAGTAAATGCAAAATCTGCTATGAGCTCTGGCGGAGCATTAACTATAAGAACCTAC
AATTTTACAGTAGATGCCTCAACTACACCTAAGGGTATGTTTGCACCAGATAAAGATCGAATCGAGCATGGTGAGTACGT
TGTACTTGAAGTCATAGACACTGGACATGGAATAGATAAAAACATAATGAAGAAGATTTTTGATCCCTTCTTCTCAACAC
AAAGTGATACTTATGGCACAGGCTTGGGACTCTCAACTGTATATGGCATAGTAAAGCAAACCGGTGGTTACATATACGTA
AAGAGTAAGGTAGGAGAAGGTACAAAGTTTATGATCTTCCTACCAAGAATATACGCAACTGAAGGTCAAGAAGTAGGAAA
TCGCTCCGTATCAGATGAAAATACAGTAGAAAAAGAACTATTAGAAGGAGGGCTACTATTACCTAATGCAGCAACTGTTT
TGCTTGTAGAAGACGAGGATCCAGTCAGGGCATTTACTTCGAAAGCGTTGTCACGCAGGGGTTTTAATGTCATAGATACA
AATTCGGGAAAAGATGCCATAATTGCAGCATCCGATAACCACATAGATGTTATTATCAGCGACGTGGTAATGCCAGGTAC
TAGTGGACCTGAAACCGTAAATGAAGTGTTAAAAATACAACCCAACACCAAGGTTATATTTGTCTCTGGATATGCTGAAG
AAGTGTTCCATCAGCAACATAAAGGGATAGATTTCAATGAAATACTATTTTTATCAAAACCATTTACATTAAAGCAATTA
TTACAAAAAGTAGATGAGGCTCTAGCGTGCAAAGGCCAGAAATAA

Upstream 100 bases:

>100_bases
GGGGCGCTTAATCGGCCTTTTCTGTGTTGAGCAACGAGCTGGGAGTTGGTAGGTGCATAAGAGGTATACAGACAGTGAAC
GGAATCATAAAGTCGACTTT

Downstream 100 bases:

>100_bases
GCACAATATGCACAGAAATATAATATCCCTAGAGAGGACTTGTCGATATGAGTAGTACGCTGCTTTTAATATACACTACA
ATGCCAGATCATGATAGCGC

Product: sensor histidine kinase/response regulator

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 814; Mature: 814

Protein sequence:

>814_residues
MIRDYGITKIKAAIVVILPLLCIFSIYLFGIENGYVSMVFNCLFTSAIVLVLLQKLSRYPKVIAAIEYQNMIFANALNHD
TEFCLILNGQGNVVYSDARFNTRFQNFTQNGNLNLYNVLKLGNLSDKEISRFLGALKNKSPVRTYCSVSKKNTVSNFSLI
LDPIVNNPQVDINTEATFSLFLSPLSRPQDYFVLKAVKITKEDVHEKLLNRHNVGSYLLSQDGVIISANATFLKIFELDT
LKRHTLLSDFLSKNQSDSETDEVVFLTSTGTMFRAYVTQEVFHDKNNNSYIYGLITPKKFDLTDYQLNPCFIHSPIAIAQ
CNMDGKIIKYNKAFEALVDKQHQEYIYSHLTAVYSKKIKKYLQNSVINNMSIEGQLCNKTYVKIYMNKLIHNNTVSVVCY
ITDSADRKSLETQLEQSQKVQAIGQLTGGIAHDFNNILTAIIGFCDLLLIQHPATDPSFRDIMQIKQNANRAANLIRQLM
AFSRKQTLQPKILDINNIVADLAQMIKRLISEDIELNIYYQENIGLVMVDLSQLEQVIVNLVVNAKSAMSSGGALTIRTY
NFTVDASTTPKGMFAPDKDRIEHGEYVVLEVIDTGHGIDKNIMKKIFDPFFSTQSDTYGTGLGLSTVYGIVKQTGGYIYV
KSKVGEGTKFMIFLPRIYATEGQEVGNRSVSDENTVEKELLEGGLLLPNAATVLLVEDEDPVRAFTSKALSRRGFNVIDT
NSGKDAIIAASDNHIDVIISDVVMPGTSGPETVNEVLKIQPNTKVIFVSGYAEEVFHQQHKGIDFNEILFLSKPFTLKQL
LQKVDEALACKGQK

Sequences:

>Translated_814_residues
MIRDYGITKIKAAIVVILPLLCIFSIYLFGIENGYVSMVFNCLFTSAIVLVLLQKLSRYPKVIAAIEYQNMIFANALNHD
TEFCLILNGQGNVVYSDARFNTRFQNFTQNGNLNLYNVLKLGNLSDKEISRFLGALKNKSPVRTYCSVSKKNTVSNFSLI
LDPIVNNPQVDINTEATFSLFLSPLSRPQDYFVLKAVKITKEDVHEKLLNRHNVGSYLLSQDGVIISANATFLKIFELDT
LKRHTLLSDFLSKNQSDSETDEVVFLTSTGTMFRAYVTQEVFHDKNNNSYIYGLITPKKFDLTDYQLNPCFIHSPIAIAQ
CNMDGKIIKYNKAFEALVDKQHQEYIYSHLTAVYSKKIKKYLQNSVINNMSIEGQLCNKTYVKIYMNKLIHNNTVSVVCY
ITDSADRKSLETQLEQSQKVQAIGQLTGGIAHDFNNILTAIIGFCDLLLIQHPATDPSFRDIMQIKQNANRAANLIRQLM
AFSRKQTLQPKILDINNIVADLAQMIKRLISEDIELNIYYQENIGLVMVDLSQLEQVIVNLVVNAKSAMSSGGALTIRTY
NFTVDASTTPKGMFAPDKDRIEHGEYVVLEVIDTGHGIDKNIMKKIFDPFFSTQSDTYGTGLGLSTVYGIVKQTGGYIYV
KSKVGEGTKFMIFLPRIYATEGQEVGNRSVSDENTVEKELLEGGLLLPNAATVLLVEDEDPVRAFTSKALSRRGFNVIDT
NSGKDAIIAASDNHIDVIISDVVMPGTSGPETVNEVLKIQPNTKVIFVSGYAEEVFHQQHKGIDFNEILFLSKPFTLKQL
LQKVDEALACKGQK
>Mature_814_residues
MIRDYGITKIKAAIVVILPLLCIFSIYLFGIENGYVSMVFNCLFTSAIVLVLLQKLSRYPKVIAAIEYQNMIFANALNHD
TEFCLILNGQGNVVYSDARFNTRFQNFTQNGNLNLYNVLKLGNLSDKEISRFLGALKNKSPVRTYCSVSKKNTVSNFSLI
LDPIVNNPQVDINTEATFSLFLSPLSRPQDYFVLKAVKITKEDVHEKLLNRHNVGSYLLSQDGVIISANATFLKIFELDT
LKRHTLLSDFLSKNQSDSETDEVVFLTSTGTMFRAYVTQEVFHDKNNNSYIYGLITPKKFDLTDYQLNPCFIHSPIAIAQ
CNMDGKIIKYNKAFEALVDKQHQEYIYSHLTAVYSKKIKKYLQNSVINNMSIEGQLCNKTYVKIYMNKLIHNNTVSVVCY
ITDSADRKSLETQLEQSQKVQAIGQLTGGIAHDFNNILTAIIGFCDLLLIQHPATDPSFRDIMQIKQNANRAANLIRQLM
AFSRKQTLQPKILDINNIVADLAQMIKRLISEDIELNIYYQENIGLVMVDLSQLEQVIVNLVVNAKSAMSSGGALTIRTY
NFTVDASTTPKGMFAPDKDRIEHGEYVVLEVIDTGHGIDKNIMKKIFDPFFSTQSDTYGTGLGLSTVYGIVKQTGGYIYV
KSKVGEGTKFMIFLPRIYATEGQEVGNRSVSDENTVEKELLEGGLLLPNAATVLLVEDEDPVRAFTSKALSRRGFNVIDT
NSGKDAIIAASDNHIDVIISDVVMPGTSGPETVNEVLKIQPNTKVIFVSGYAEEVFHQQHKGIDFNEILFLSKPFTLKQL
LQKVDEALACKGQK

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=250, Percent_Identity=28.4, Blast_Score=112, Evalue=9e-26,
Organism=Escherichia coli, GI1788549, Length=267, Percent_Identity=27.3408239700375, Blast_Score=108, Evalue=9e-25,
Organism=Escherichia coli, GI1788713, Length=530, Percent_Identity=21.8867924528302, Blast_Score=83, Evalue=6e-17,
Organism=Escherichia coli, GI1790300, Length=262, Percent_Identity=28.2442748091603, Blast_Score=76, Evalue=1e-14,
Organism=Escherichia coli, GI1786912, Length=275, Percent_Identity=26.1818181818182, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI48994928, Length=522, Percent_Identity=22.0306513409962, Blast_Score=74, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 91212; Mature: 91212

Theoretical pI: Translated: 7.22; Mature: 7.22

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRDYGITKIKAAIVVILPLLCIFSIYLFGIENGYVSMVFNCLFTSAIVLVLLQKLSRYP
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
KVIAAIEYQNMIFANALNHDTEFCLILNGQGNVVYSDARFNTRFQNFTQNGNLNLYNVLK
CEEEEEEHHHHHEEHHCCCCCCEEEEECCCCCEEEECCCCCCHHHHHCCCCCEEEEEEEE
LGNLSDKEISRFLGALKNKSPVRTYCSVSKKNTVSNFSLILDPIVNNPQVDINTEATFSL
ECCCCHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCHHEEEECCCCCCCEEECCCHHHHH
FLSPLSRPQDYFVLKAVKITKEDVHEKLLNRHNVGSYLLSQDGVIISANATFLKIFELDT
HHHHCCCCCCEEEEEEEHHHHHHHHHHHHHHCCCCCCEECCCCEEEECCCCEEEEEEHHH
LKRHTLLSDFLSKNQSDSETDEVVFLTSTGTMFRAYVTQEVFHDKNNNSYIYGLITPKKF
HHHHHHHHHHHHCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCEEEEEECCCEE
DLTDYQLNPCFIHSPIAIAQCNMDGKIIKYNKAFEALVDKQHQEYIYSHLTAVYSKKIKK
CCCCEECCCEEEECCEEEEEECCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YLQNSVINNMSIEGQLCNKTYVKIYMNKLIHNNTVSVVCYITDSADRKSLETQLEQSQKV
HHHHHHHCCCCCCCEECCHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHHHHHH
QAIGQLTGGIAHDFNNILTAIIGFCDLLLIQHPATDPSFRDIMQIKQNANRAANLIRQLM
HHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCHHHHHHHHHHHH
AFSRKQTLQPKILDINNIVADLAQMIKRLISEDIELNIYYQENIGLVMVDLSQLEQVIVN
HHHHHHCCCCCEECHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEEHHHHHHHHHH
LVVNAKSAMSSGGALTIRTYNFTVDASTTPKGMFAPDKDRIEHGEYVVLEVIDTGHGIDK
HHHCCHHHHCCCCEEEEEEEEEEEECCCCCCCCCCCCHHHCCCCCEEEEEEEECCCCCCH
NIMKKIFDPFFSTQSDTYGTGLGLSTVYGIVKQTGGYIYVKSKVGEGTKFMIFLPRIYAT
HHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCEEEEEECEEECC
EGQEVGNRSVSDENTVEKELLEGGLLLPNAATVLLVEDEDPVRAFTSKALSRRGFNVIDT
CCHHHCCCCCCCCHHHHHHHHCCCEECCCCEEEEEEECCCHHHHHHHHHHHHCCCEEEEC
NSGKDAIIAASDNHIDVIISDVVMPGTSGPETVNEVLKIQPNTKVIFVSGYAEEVFHQQH
CCCCCEEEEECCCCEEEEEEEEECCCCCCHHHHHHHEEECCCCEEEEEECHHHHHHHHHH
KGIDFNEILFLSKPFTLKQLLQKVDEALACKGQK
CCCCHHHEEEECCCHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MIRDYGITKIKAAIVVILPLLCIFSIYLFGIENGYVSMVFNCLFTSAIVLVLLQKLSRYP
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
KVIAAIEYQNMIFANALNHDTEFCLILNGQGNVVYSDARFNTRFQNFTQNGNLNLYNVLK
CEEEEEEHHHHHEEHHCCCCCCEEEEECCCCCEEEECCCCCCHHHHHCCCCCEEEEEEEE
LGNLSDKEISRFLGALKNKSPVRTYCSVSKKNTVSNFSLILDPIVNNPQVDINTEATFSL
ECCCCHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCHHEEEECCCCCCCEEECCCHHHHH
FLSPLSRPQDYFVLKAVKITKEDVHEKLLNRHNVGSYLLSQDGVIISANATFLKIFELDT
HHHHCCCCCCEEEEEEEHHHHHHHHHHHHHHCCCCCCEECCCCEEEECCCCEEEEEEHHH
LKRHTLLSDFLSKNQSDSETDEVVFLTSTGTMFRAYVTQEVFHDKNNNSYIYGLITPKKF
HHHHHHHHHHHHCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCEEEEEECCCEE
DLTDYQLNPCFIHSPIAIAQCNMDGKIIKYNKAFEALVDKQHQEYIYSHLTAVYSKKIKK
CCCCEECCCEEEECCEEEEEECCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YLQNSVINNMSIEGQLCNKTYVKIYMNKLIHNNTVSVVCYITDSADRKSLETQLEQSQKV
HHHHHHHCCCCCCCEECCHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHHHHHH
QAIGQLTGGIAHDFNNILTAIIGFCDLLLIQHPATDPSFRDIMQIKQNANRAANLIRQLM
HHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCHHHHHHHHHHHH
AFSRKQTLQPKILDINNIVADLAQMIKRLISEDIELNIYYQENIGLVMVDLSQLEQVIVN
HHHHHHCCCCCEECHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEEHHHHHHHHHH
LVVNAKSAMSSGGALTIRTYNFTVDASTTPKGMFAPDKDRIEHGEYVVLEVIDTGHGIDK
HHHCCHHHHCCCCEEEEEEEEEEEECCCCCCCCCCCCHHHCCCCCEEEEEEEECCCCCCH
NIMKKIFDPFFSTQSDTYGTGLGLSTVYGIVKQTGGYIYVKSKVGEGTKFMIFLPRIYAT
HHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCEEEEEECEEECC
EGQEVGNRSVSDENTVEKELLEGGLLLPNAATVLLVEDEDPVRAFTSKALSRRGFNVIDT
CCHHHCCCCCCCCHHHHHHHHCCCEECCCCEEEEEEECCCHHHHHHHHHHHHCCCEEEEC
NSGKDAIIAASDNHIDVIISDVVMPGTSGPETVNEVLKIQPNTKVIFVSGYAEEVFHQQH
CCCCCEEEEECCCCEEEEEEEEECCCCCCHHHHHHHEEECCCCEEEEEECHHHHHHHHHH
KGIDFNEILFLSKPFTLKQLLQKVDEALACKGQK
CCCCHHHEEEECCCHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA