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The map label for this gene is ccmG [H]

Identifier: 88607544

GI number: 88607544

Start: 145621

End: 146121

Strand: Reverse

Name: ccmG [H]

Synonym: APH_0141

Alternate gene names: 88607544

Gene position: 146121-145621 (Counterclockwise)

Preceding gene: 88607157

Following gene: 88607008

Centisome position: 9.93

GC content: 40.72

Gene sequence:

>501_bases
ATGCGCATAGTAGTAATAAGCGTGCTGTGTTTATTTTGCGCTTTTTCAGCCATCGTATTTTTTACTTACTACAGGCGCAA
CAGTGCCACATTTTCTTACGATATAGTATTGCCTACCATATTCGGTAACAGTACAGAATTTAACACCTCAGAGATCAAGA
AAAAAAGACGTGCGTTTGTGGTGAATGTGTTTGCTTCCTGGTGTACTGTTTGTATGCAGGAGCACCAAACATGGAAAGAA
ATCTCTAAAAGAACCCCCATCGATCTTTATGGCATAGACTACATAGATATAGAGGATAACGCACTGGCTTGGCTGCAGGA
ACCTGATAACCCTTATATTGCAATTGCGGCCGATTACTCCGGAAAAGCAGCAAAGGCATTTGGGGTTACGGGAGTACCTG
AAACTTTTATTTTCAACAAAAAAGGTGAATTAGTGCTCCATATAAAGGGTTCTATAACCTGGGAACTATGGCAAGAACGT
GTCGCAAAACTCATCTCATAA

Upstream 100 bases:

>100_bases
AGCAAAATTAAGCTTTCCCTAGTGATCTGTTGCGAAAACTATAAAGTCAATGCACACTGCATGCACTATCCCGTAACATG
ATCAACTTAGGGAGTATTAC

Downstream 100 bases:

>100_bases
ACGTATACATACAAAGCCTCGGTAAGTAAGAGTTTTGTGCTGCTAGCATAAACAATAACCATTCAAATAAGACAGGCAGT
TCAACTTATGCAATTAACTG

Product: putative thiol:disulfide oxidoreductase

Products: NA

Alternate protein names: Cytochrome c biogenesis protein CcmG [H]

Number of amino acids: Translated: 166; Mature: 166

Protein sequence:

>166_residues
MRIVVISVLCLFCAFSAIVFFTYYRRNSATFSYDIVLPTIFGNSTEFNTSEIKKKRRAFVVNVFASWCTVCMQEHQTWKE
ISKRTPIDLYGIDYIDIEDNALAWLQEPDNPYIAIAADYSGKAAKAFGVTGVPETFIFNKKGELVLHIKGSITWELWQER
VAKLIS

Sequences:

>Translated_166_residues
MRIVVISVLCLFCAFSAIVFFTYYRRNSATFSYDIVLPTIFGNSTEFNTSEIKKKRRAFVVNVFASWCTVCMQEHQTWKE
ISKRTPIDLYGIDYIDIEDNALAWLQEPDNPYIAIAADYSGKAAKAFGVTGVPETFIFNKKGELVLHIKGSITWELWQER
VAKLIS
>Mature_166_residues
MRIVVISVLCLFCAFSAIVFFTYYRRNSATFSYDIVLPTIFGNSTEFNTSEIKKKRRAFVVNVFASWCTVCMQEHQTWKE
ISKRTPIDLYGIDYIDIEDNALAWLQEPDNPYIAIAADYSGKAAKAFGVTGVPETFIFNKKGELVLHIKGSITWELWQER
VAKLIS

Specific function: Required for disulfide bond formation in some periplasmic proteins. Also act as a disulfide oxidoreductase in cytochromes c biogenesis. The cysteines of apocytochromes c must be in the reduced state for covalent linkage between the two moieties to occur [

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1788523, Length=174, Percent_Identity=25.8620689655172, Blast_Score=78, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004799
- InterPro:   IPR013740
- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF08534 Redoxin [H]

EC number: NA

Molecular weight: Translated: 19012; Mature: 19012

Theoretical pI: Translated: 7.93; Mature: 7.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIVVISVLCLFCAFSAIVFFTYYRRNSATFSYDIVLPTIFGNSTEFNTSEIKKKRRAFV
CEEHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEEECCCCCCCHHHHHHHHHHHH
VNVFASWCTVCMQEHQTWKEISKRTPIDLYGIDYIDIEDNALAWLQEPDNPYIAIAADYS
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCEEEEECCCEEEEEECCCCCEEEEEECCC
GKAAKAFGVTGVPETFIFNKKGELVLHIKGSITWELWQERVAKLIS
CCCEEECCCCCCCHHEEECCCCCEEEEECCCEEHHHHHHHHHHHCC
>Mature Secondary Structure
MRIVVISVLCLFCAFSAIVFFTYYRRNSATFSYDIVLPTIFGNSTEFNTSEIKKKRRAFV
CEEHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEEECCCCCCCHHHHHHHHHHHH
VNVFASWCTVCMQEHQTWKEISKRTPIDLYGIDYIDIEDNALAWLQEPDNPYIAIAADYS
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCEEEEECCCEEEEEECCCCCEEEEEECCC
GKAAKAFGVTGVPETFIFNKKGELVLHIKGSITWELWQERVAKLIS
CCCEEECCCCCCCHHEEECCCCCEEEEECCCEEHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9220005 [H]